JP2017531634A5 - - Google Patents
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- Publication number
- JP2017531634A5 JP2017531634A5 JP2017517121A JP2017517121A JP2017531634A5 JP 2017531634 A5 JP2017531634 A5 JP 2017531634A5 JP 2017517121 A JP2017517121 A JP 2017517121A JP 2017517121 A JP2017517121 A JP 2017517121A JP 2017531634 A5 JP2017531634 A5 JP 2017531634A5
- Authority
- JP
- Japan
- Prior art keywords
- rebaudioside
- udp
- glucose
- reaction mixture
- glycosyltransferase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930188195 rebaudioside Natural products 0.000 claims 59
- HSCJRCZFDFQWRP-JZMIEXBBSA-N UDP-alpha-D-glucose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(=O)C=C2)=O)O1 HSCJRCZFDFQWRP-JZMIEXBBSA-N 0.000 claims 22
- HSCJRCZFDFQWRP-UHFFFAOYSA-N Uridindiphosphoglukose Natural products OC1C(O)C(O)C(CO)OC1OP(O)(=O)OP(O)(=O)OCC1C(O)C(O)C(N2C(NC(=O)C=C2)=O)O1 HSCJRCZFDFQWRP-UHFFFAOYSA-N 0.000 claims 22
- DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 claims 22
- XCCTYIAWTASOJW-XVFCMESISA-N Uridine-5'-Diphosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1N1C(=O)NC(=O)C=C1 XCCTYIAWTASOJW-XVFCMESISA-N 0.000 claims 22
- 239000011541 reaction mixture Substances 0.000 claims 22
- 238000000034 method Methods 0.000 claims 18
- 239000005720 sucrose Substances 0.000 claims 12
- 101100262416 Stevia rebaudiana UGT76G1 gene Proteins 0.000 claims 11
- 229930006000 Sucrose Natural products 0.000 claims 11
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 11
- DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 claims 11
- 239000000758 substrate Substances 0.000 claims 11
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 claims 11
- 229940045145 uridine Drugs 0.000 claims 11
- 102000004190 Enzymes Human genes 0.000 claims 10
- 108090000790 Enzymes Proteins 0.000 claims 10
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 10
- 230000004927 fusion Effects 0.000 claims 10
- 239000008103 glucose Substances 0.000 claims 10
- 230000002194 synthesizing effect Effects 0.000 claims 10
- YWPVROCHNBYFTP-UHFFFAOYSA-N Rubusoside Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC1OC(CO)C(O)C(O)C1O YWPVROCHNBYFTP-UHFFFAOYSA-N 0.000 claims 8
- YWPVROCHNBYFTP-OSHKXICASA-N rubusoside Chemical compound O([C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O YWPVROCHNBYFTP-OSHKXICASA-N 0.000 claims 8
- 102000051366 Glycosyltransferases Human genes 0.000 claims 2
- 108700023372 Glycosyltransferases Proteins 0.000 claims 2
- 235000003599 food sweetener Nutrition 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 239000003765 sweetening agent Substances 0.000 claims 2
- -1 EUGT11 Chemical compound 0.000 claims 1
- 239000004067 bulking agent Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000000945 filler Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462059498P | 2014-10-03 | 2014-10-03 | |
| US62/059,498 | 2014-10-03 | ||
| US201462098929P | 2014-12-31 | 2014-12-31 | |
| US62/098,929 | 2014-12-31 | ||
| PCT/US2015/053777 WO2016054540A1 (en) | 2014-10-03 | 2015-10-02 | Non-caloric sweeteners and methods for synthesizing |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017531634A JP2017531634A (ja) | 2017-10-26 |
| JP2017531634A5 true JP2017531634A5 (cg-RX-API-DMAC7.html) | 2018-10-18 |
| JP6883512B2 JP6883512B2 (ja) | 2021-06-09 |
Family
ID=55631622
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017517349A Active JP6722177B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
| JP2017517121A Active JP6883512B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
| JP2017517085A Active JP6774945B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
| JP2017516928A Expired - Fee Related JP6854238B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017517349A Active JP6722177B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017517085A Active JP6774945B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
| JP2017516928A Expired - Fee Related JP6854238B2 (ja) | 2014-10-03 | 2015-10-02 | ノンカロリー甘味料および合成するための方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (22) | US10023604B2 (cg-RX-API-DMAC7.html) |
| EP (4) | EP3201212B1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP6722177B2 (cg-RX-API-DMAC7.html) |
| KR (4) | KR102557670B1 (cg-RX-API-DMAC7.html) |
| CN (7) | CN113603736A (cg-RX-API-DMAC7.html) |
| AU (4) | AU2015327858B2 (cg-RX-API-DMAC7.html) |
| BR (3) | BR112017006155A2 (cg-RX-API-DMAC7.html) |
| CA (4) | CA2958105C (cg-RX-API-DMAC7.html) |
| DK (3) | DK3201351T3 (cg-RX-API-DMAC7.html) |
| ES (3) | ES2869823T3 (cg-RX-API-DMAC7.html) |
| HU (2) | HUE053331T2 (cg-RX-API-DMAC7.html) |
| MX (4) | MX378831B (cg-RX-API-DMAC7.html) |
| MY (4) | MY190567A (cg-RX-API-DMAC7.html) |
| WO (4) | WO2016054534A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105051195B (zh) | 2013-02-06 | 2019-09-06 | 埃沃尔瓦公司 | 用于提高莱鲍迪苷d和莱鲍迪苷m之产生的方法 |
| US9522929B2 (en) * | 2014-05-05 | 2016-12-20 | Conagen Inc. | Non-caloric sweetener |
| US10264811B2 (en) | 2014-05-19 | 2019-04-23 | Epc Natural Products Co., Ltd. | Stevia sweetener with improved solubility |
| DK3201351T3 (da) | 2014-10-03 | 2021-02-22 | Conagen Inc | Kaloriefrie sødestoffer og fremgangsmåder til syntetisering |
| US10711024B2 (en) | 2014-12-17 | 2020-07-14 | Cargill, Incorporated | Steviol glycoside compounds, compositions for oral ingestion or use, and method for enhancing steviol glycoside solubility |
| JP2018503388A (ja) | 2015-01-30 | 2018-02-08 | エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． | 組み換え宿主におけるステビオールグリコシドの生産 |
| WO2016156616A1 (en) | 2015-04-03 | 2016-10-06 | Dsm Ip Assets B.V. | Steviol glycosides |
| BR112017022019A2 (pt) | 2015-04-14 | 2018-07-31 | Conagen Inc. | produção de adoçantes não calóricos por meio da utilização de catalisadores de células inteiras modificadas |
| US20190203244A1 (en) * | 2015-08-20 | 2019-07-04 | Pepsico, Inc. | Preparation of rebaudioside m in a single reaction vessel |
| SG11201808856TA (en) | 2016-04-13 | 2018-11-29 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| KR20190018512A (ko) | 2016-06-15 | 2019-02-22 | 코덱시스, 인코포레이티드 | 조작된 베타-글루코시다아제 및 글루코실화 방법 |
| CN110049687A (zh) * | 2016-06-17 | 2019-07-23 | 嘉吉公司 | 用于口服摄取或使用的甜菊醇糖苷组合物 |
| ES2906310T3 (es) | 2016-08-12 | 2022-04-18 | Amyris Inc | Glicosiltransferasa dependiente de UDP para la producción de alta eficiencia de rebaudiósidos |
| BR112019007504B1 (pt) | 2016-10-14 | 2023-05-09 | Conagen Inc | Método de preparação de uma composição de glicosídeo de esteviol |
| AU2016427130B2 (en) | 2016-10-21 | 2022-08-18 | Pepsico, Inc. | Method for preparing rebaudioside N using enzymatic method |
| MX2019004630A (es) * | 2016-10-21 | 2019-07-15 | Pepsico Inc | Metodo para preparar rebaudiosido j usando el metodo enzimatico. |
| WO2018093196A1 (ko) * | 2016-11-17 | 2018-05-24 | 서울대학교산학협력단 | 변형 류코노스톡속 균주를 이용한 스테비오사이드 배당체의 합성 방법 및 이에 의하여 제조된 신규한 스테비오사이드 배당체 |
| BR112019011200B1 (pt) | 2016-12-01 | 2021-12-28 | Arvinas Operations, Inc | Derivados de tetrahidronaftaleno e tetrahidroisoquinolina como degradadores do receptor de estrogênio |
| CN110914445B (zh) | 2017-02-03 | 2024-08-27 | 泰莱解决方案美国有限责任公司 | 工程化糖基转移酶和甜菊醇糖苷葡糖基化方法 |
| CN111031805B (zh) * | 2017-04-25 | 2023-11-17 | 可口可乐公司 | 二氢查耳酮对甜菊醇糖苷和罗汉果苷甜味剂的甜度和味道改善 |
| CN107164435B (zh) * | 2017-05-27 | 2020-03-31 | 中国药科大学 | 一种莱鲍迪苷ka的制备方法 |
| SG11201911674YA (en) * | 2017-06-08 | 2020-01-30 | Suntory Holdings Ltd | Food or beverage with increased sweetness |
| AU2018294258A1 (en) | 2017-06-30 | 2020-02-06 | Conagen Inc. | Hydrolysis of steviol glycosides by beta-glucosidase |
| CN111868252B (zh) | 2018-03-12 | 2025-06-03 | 科纳根公司 | 甜菊糖苷莱苞迪苷j和莱苞迪苷n的生物合成生产 |
| CN115997912B (zh) * | 2018-05-08 | 2025-05-13 | 伊比西(北京)植物药物技术有限公司 | 具有改善风味剖面的甜菊醇糖甙组合物 |
| CN109021038B (zh) * | 2018-06-11 | 2021-07-27 | 江西师范大学 | 一种甜菊糖苷的制备方法 |
| JP7584401B2 (ja) * | 2018-07-30 | 2024-11-15 | テイト アンド ライル ソリューションズ ユー・エス・エー エル・エル・シー | 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法 |
| CN110913864B (zh) * | 2018-08-17 | 2022-12-13 | 邦泰生物工程(深圳)有限公司 | 一种稳定型烟酰胺核糖组合物及其制备方法 |
| CN111073923A (zh) * | 2018-10-22 | 2020-04-28 | 山东三元生物科技股份有限公司 | 一种莱鲍迪苷m的酶法制备方法 |
| CN113302298B (zh) | 2018-11-09 | 2025-02-25 | 银杏生物制品公司 | 罗汉果甙的生物合成 |
| US12232507B2 (en) | 2018-12-07 | 2025-02-25 | Suntory Holdings Limited | Coffee beverage having improved quality of taste exhibited by sugar, sweetener, and sodium |
| WO2020116665A1 (en) * | 2018-12-07 | 2020-06-11 | Suntory Holdings Limited | Composition |
| MY208984A (en) * | 2018-12-07 | 2025-06-14 | Suntory Holdings Ltd | Composition |
| US20210337823A1 (en) * | 2018-12-07 | 2021-11-04 | Suntory Holdings Limited | Coffee beverage having improved quality of taste exhibited by sugar and sweetener |
| CN113474464B (zh) * | 2018-12-12 | 2025-06-10 | 科纳根公司 | 变体甜菊醇糖苷的生物合成生产 |
| CN109750072B (zh) * | 2019-01-31 | 2022-04-19 | 南京工业大学 | 一种酶法制备莱鲍迪苷e的方法 |
| EP3799057A1 (en) | 2019-09-25 | 2021-03-31 | Koninklijke Philips N.V. | Prediction tool for patient immune response to a therapy |
| US20240148037A1 (en) * | 2019-10-16 | 2024-05-09 | Sweegen, Inc. | Steviol glycoside formulations for food and beverages |
| CN110846305B (zh) * | 2019-11-11 | 2023-11-28 | 中化健康产业发展有限公司 | 一种固定化糖基转移酶催化莱鲍迪苷a生成莱鲍迪苷m的方法 |
| CN110846363B (zh) * | 2019-11-11 | 2023-02-17 | 天津大学 | 一锅法生产莱鲍迪苷d的方法 |
| CN110734944B (zh) * | 2019-11-11 | 2023-02-21 | 中化健康产业发展有限公司 | 一步法合成莱鲍迪苷m的方法 |
| CN110872586B (zh) * | 2019-11-11 | 2024-01-30 | 天津大学 | 固定化葡萄糖基转移酶及制备方法及催化生产莱鲍迪苷d的方法 |
| MX2022011329A (es) * | 2020-03-13 | 2022-10-07 | Amyris Inc | Composiciones edulcorantes de rebaudiosido m. |
| AU2021258138A1 (en) | 2020-04-20 | 2022-12-01 | The Coca-Cola Company | Beverages comprising siamenoside i with enhanced flavor |
| EP4269573A4 (en) * | 2020-12-23 | 2025-07-23 | Samyang Corp | GLYCOSYLTRANSFERASE AND METHOD FOR PREPARING STEVIOL GLUCOSIDE USING SAME |
| JP7210626B2 (ja) * | 2021-02-18 | 2023-01-23 | ペプシコ・インク | 酵素的方法を使用してレバウディオサイドｊを調製するための方法 |
| JP2025500510A (ja) * | 2021-12-24 | 2025-01-09 | サムヤン コーポレイション | 糖転移酵素変異体、およびこれを利用したステビオール配糖体の製造方法 |
| US12446605B2 (en) | 2022-03-23 | 2025-10-21 | Sweegen, Inc. | Sweeteners |
| CN114921434B (zh) * | 2022-05-27 | 2024-02-20 | 中化健康产业发展有限公司 | 催化Reb A生产Reb M的重组糖基转移酶 |
| DE202022103252U1 (de) | 2022-06-09 | 2022-07-01 | Wal Ankita | Eine natürliche Süßstoffzusammensetzung als Süßungsmittel für Diabetes |
| CN116076694B (zh) * | 2022-10-12 | 2024-06-28 | 四川盈嘉合生科技有限公司 | 一种甜菊糖苷甜味剂及其制备方法 |
| CN117209563B (zh) * | 2023-09-15 | 2025-09-19 | 郑州大学 | 呈味肽及其应用 |
| WO2025143773A1 (ko) * | 2023-12-26 | 2025-07-03 | 주식회사 삼양사 | 수크로우스 합성효소 변이체, udp-글루코실트랜스퍼라제 변이체 및 이들의 스테비올 배당체 생산 용도 |
| KR102777875B1 (ko) * | 2024-10-22 | 2025-03-13 | 대한민국 | 신규 페디오코커스 속 균주 및 그의 용도 |
| CN119842657B (zh) * | 2025-03-18 | 2025-05-27 | 青岛奔月生物技术有限公司 | 蔗糖合酶突变体及其应用 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US17804A (en) * | 1857-07-14 | Improvement in locks | ||
| US4612942A (en) | 1984-03-08 | 1986-09-23 | Stevia Company, Inc. | Flavor enhancing and modifying materials |
| JPH04149191A (ja) * | 1990-10-09 | 1992-05-22 | Nakano Vinegar Co Ltd | ステビオサイド糖転移化合物及びその製造方法 |
| US20090183270A1 (en) | 2002-10-02 | 2009-07-16 | Adams Thomas R | Transgenic plants with enhanced agronomic traits |
| US9107436B2 (en) | 2011-02-17 | 2015-08-18 | Purecircle Sdn Bhd | Glucosylated steviol glycoside as a flavor modifier |
| CN101528059B (zh) * | 2006-10-24 | 2012-12-05 | 奇华顿股份有限公司 | 消费品 |
| US8277862B2 (en) | 2007-03-14 | 2012-10-02 | Concentrate Manufacturing Company Of Ireland | Beverage products having steviol glycosides and at least one acid |
| US20130071521A1 (en) | 2007-03-14 | 2013-03-21 | Pepsico, Inc. | Rebaudioside d sweeteners and food products sweetened with rebaudioside d |
| ES2592377T3 (es) | 2008-10-03 | 2016-11-29 | Morita Kagaku Kogyo Co., Ltd. | Nuevos glucósidos de esteviol |
| US8501261B2 (en) * | 2010-05-21 | 2013-08-06 | Purecircle Sdn Bhd | High-purity Rebaudioside C and process for purification of the same |
| NZ604915A (en) * | 2010-06-02 | 2014-10-31 | Evolva Nutrition Inc | Recombinant production of steviol glycosides |
| WO2012075030A1 (en) * | 2010-11-30 | 2012-06-07 | Massachusetts Institute Of Technology | Microbial production of natural sweeteners, diterpenoid steviol glycosides |
| SG10201606567TA (en) * | 2011-08-08 | 2016-10-28 | Evolva Sa | Recombinant production of steviol glycosides |
| EP3345490B1 (en) * | 2011-12-19 | 2023-11-08 | The Coca-Cola Company | Beverage comprising rebaudioside x |
| US10000783B2 (en) | 2012-03-16 | 2018-06-19 | Suntory Holdings Limited | Steviol glucosyltransferases and genes encoding the same |
| US9752174B2 (en) * | 2013-05-28 | 2017-09-05 | Purecircle Sdn Bhd | High-purity steviol glycosides |
| CN110358795B (zh) * | 2012-05-22 | 2024-12-03 | 谱赛科有限责任公司 | 高纯度的甜菊醇糖苷 |
| WO2014048392A1 (zh) * | 2012-09-29 | 2014-04-03 | 中国科学院上海生命科学研究院 | 利用微生物生产甜菊糖苷类化合物的方法 |
| CN105051195B (zh) * | 2013-02-06 | 2019-09-06 | 埃沃尔瓦公司 | 用于提高莱鲍迪苷d和莱鲍迪苷m之产生的方法 |
| CN105189771B (zh) * | 2013-02-11 | 2019-11-05 | 埃沃尔瓦公司 | 在重组宿主中有效产生甜菊醇糖苷 |
| US9717267B2 (en) * | 2013-03-14 | 2017-08-01 | The Coca-Cola Company | Beverages containing rare sugars |
| CA2900849A1 (en) | 2013-03-14 | 2014-09-25 | Chromocell Corporation | Compounds, compositions, and methods for modulating sweet taste |
| CN105283464B (zh) | 2013-03-15 | 2018-02-13 | 可口可乐公司 | 甜菊醇糖苷、其组合物以及其纯化 |
| US20140342043A1 (en) | 2013-05-14 | 2014-11-20 | Pepsico, Inc. | Rebaudioside Sweetener Compositions and Food Products Sweetened with Same |
| TWI657746B (zh) | 2013-06-19 | 2019-05-01 | 美商科納根股份有限公司 | 含有甜葉菊苷ｅ之可食用產品及使用其製備和強化可食用產品之甜味的方法 |
| MX2016000452A (es) | 2013-07-15 | 2016-05-12 | Dsm Ip Assets Bv | Produccion de diterpeno. |
| CN103397064B (zh) * | 2013-08-14 | 2015-04-15 | 苏州汉酶生物技术有限公司 | 一种酶法制备瑞鲍迪甙m的方法 |
| CN106103729B (zh) | 2013-11-01 | 2020-07-07 | 科纳根公司 | 甜菊醇糖苷的重组制备 |
| CA2937426C (en) | 2014-01-28 | 2023-03-21 | Pepsico Inc. | Rebaudioside m enzymatic preparation method |
| US9522929B2 (en) | 2014-05-05 | 2016-12-20 | Conagen Inc. | Non-caloric sweetener |
| EP3677122A1 (en) | 2014-09-30 | 2020-07-08 | Suntory Holdings Limited | Carbonated beverage, syrup used for preparing carbonated beverage, method for manufacturing carbonated beverage, and method for suppressing foaming in carbonated beverage |
| DK3201351T3 (da) | 2014-10-03 | 2021-02-22 | Conagen Inc | Kaloriefrie sødestoffer og fremgangsmåder til syntetisering |
| BR112017022019A2 (pt) * | 2015-04-14 | 2018-07-31 | Conagen Inc. | produção de adoçantes não calóricos por meio da utilização de catalisadores de células inteiras modificadas |
| CN110049687A (zh) * | 2016-06-17 | 2019-07-23 | 嘉吉公司 | 用于口服摄取或使用的甜菊醇糖苷组合物 |
| BR112019007504B1 (pt) * | 2016-10-14 | 2023-05-09 | Conagen Inc | Método de preparação de uma composição de glicosídeo de esteviol |
| CN113474464B (zh) * | 2018-12-12 | 2025-06-10 | 科纳根公司 | 变体甜菊醇糖苷的生物合成生产 |
| US20240148037A1 (en) * | 2019-10-16 | 2024-05-09 | Sweegen, Inc. | Steviol glycoside formulations for food and beverages |
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