JP2017530692A5 - - Google Patents
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- Publication number
- JP2017530692A5 JP2017530692A5 JP2017506267A JP2017506267A JP2017530692A5 JP 2017530692 A5 JP2017530692 A5 JP 2017530692A5 JP 2017506267 A JP2017506267 A JP 2017506267A JP 2017506267 A JP2017506267 A JP 2017506267A JP 2017530692 A5 JP2017530692 A5 JP 2017530692A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- binding fragment
- cancer
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1413913.3 | 2014-08-06 | ||
| GBGB1413913.3A GB201413913D0 (en) | 2014-08-06 | 2014-08-06 | Novel antibodies and uses thereof |
| PCT/EP2015/068208 WO2016020502A1 (en) | 2014-08-06 | 2015-08-06 | Novel antibodies and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530692A JP2017530692A (ja) | 2017-10-19 |
| JP2017530692A5 true JP2017530692A5 (enExample) | 2018-08-30 |
| JP6827411B2 JP6827411B2 (ja) | 2021-02-10 |
Family
ID=51587804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017506267A Active JP6827411B2 (ja) | 2014-08-06 | 2015-08-06 | 新規の抗体及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10100119B2 (enExample) |
| EP (1) | EP3193926B1 (enExample) |
| JP (1) | JP6827411B2 (enExample) |
| KR (1) | KR20170039685A (enExample) |
| CN (1) | CN107074946B (enExample) |
| AU (1) | AU2015298852A1 (enExample) |
| BR (1) | BR112017002342A2 (enExample) |
| CA (1) | CA2955056A1 (enExample) |
| GB (1) | GB201413913D0 (enExample) |
| MX (1) | MX2017001599A (enExample) |
| WO (1) | WO2016020502A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2472856B (en) | 2009-08-21 | 2012-07-11 | Cantargia Ab | IL1-RAP modulators and uses thereof |
| RU2597831C2 (ru) | 2011-01-19 | 2016-09-20 | Кантаргия Аб | Анти-il1rap антитела и их применение при лечении людей |
| GB201403875D0 (en) | 2014-03-05 | 2014-04-16 | Cantargia Ab | Novel antibodies and uses thereof |
| CA2960297A1 (en) | 2014-11-10 | 2016-05-19 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| EP3218515B1 (en) | 2014-11-10 | 2023-04-26 | F. Hoffmann-La Roche AG | Therapeutic and diagnostic methods for il-33-mediated disorders |
| CA2990305A1 (en) | 2015-06-26 | 2016-12-29 | Mab Discovery Gmbh | Monoclonal anti-il-1racp antibodies |
| EP3421089B1 (en) * | 2016-04-19 | 2020-05-13 | Neuboron Medtech Ltd. | Neutron capture therapy system for eliminating amyloid -protein plaque |
| EP3241845A1 (en) | 2016-05-06 | 2017-11-08 | MAB Discovery GmbH | Humanized anti-il-1r3 antibodies |
| US11359025B2 (en) | 2016-10-16 | 2022-06-14 | Cantargia Ab | Anti-IL1-RAP antibodies |
| FI3548515T3 (fi) | 2016-12-01 | 2026-03-04 | Regeneron Pharma | Radioleimattuja anti-PD-L1-vasta-aineita immuno-PET-kuvantamiseen |
| AU2018219909B2 (en) | 2017-02-10 | 2025-02-27 | Regeneron Pharmaceuticals, Inc. | Radiolabeled anti-LAG3 antibodies for immuno-PET imaging |
| EP3401332A1 (en) * | 2017-05-08 | 2018-11-14 | MAB Discovery GmbH | Anti-il-1r3 antibodies for use in inflammatory conditions |
| JP7657440B2 (ja) * | 2017-06-12 | 2025-04-07 | ブルーフィン バイオメディシン， インコーポレイテッド | 抗－ｉｌ１ｒａｐ抗体および抗体薬物コンジュゲート |
| IL316355A (en) | 2017-07-24 | 2024-12-01 | Regeneron Pharma | Anti-CD8 antibodies and their uses |
| JP2020533960A (ja) * | 2017-08-01 | 2020-11-26 | シティ・オブ・ホープＣｉｔｙ ｏｆ Ｈｏｐｅ | 抗ｉｌ１ｒａｐ抗体 |
| EP3489259A1 (en) * | 2017-11-23 | 2019-05-29 | Etablissement Français du Sang | Anti-il-1rap-car-t cells and their use |
| WO2019161080A1 (en) * | 2018-02-14 | 2019-08-22 | Yale University | Compositions for modulation of a trem or treml protein and methods of use |
| CN112638946A (zh) * | 2018-08-16 | 2021-04-09 | 坎塔吉亚有限责任公司 | 抗il1rap抗体组合物 |
| TW202021618A (zh) * | 2018-08-17 | 2020-06-16 | 美商２３與我有限公司 | 抗ｉｌ１ｒａｐ抗體及其使用方法 |
| WO2020176478A1 (en) | 2019-02-25 | 2020-09-03 | The University Of Chicago | Methods and compositions for treating inflammatory and autoimmune conditions with ecm-affinity peptides linked to anti-inflammatory agents |
| WO2021148884A1 (en) * | 2020-01-24 | 2021-07-29 | Tychan Pte. Ltd. | Anti-wuhan coronavirus antibodies |
| CA3174680A1 (en) | 2020-03-13 | 2021-09-16 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| CN115942975A (zh) * | 2020-04-10 | 2023-04-07 | 西雅图儿童医院（Dba西雅图儿童研究所） | 白细胞介素-1受体辅助蛋白的特异性结合域和嵌合抗原受体 |
| JP2023541627A (ja) | 2020-09-14 | 2023-10-03 | イシュノス サイエンシズ ソシエテ アノニム | Ｉｌ１ｒａｐに結合する抗体及びその使用 |
| CN116635064A (zh) | 2020-12-18 | 2023-08-22 | 世纪治疗股份有限公司 | 具有适应性受体特异性的嵌合抗原受体系统 |
| US20220411517A1 (en) | 2021-05-21 | 2022-12-29 | Leo Pharma A/S | IL-1 Receptor Accessory Protein Inhibitors and Uses Thereof |
| AU2023314605A1 (en) | 2022-07-25 | 2025-01-09 | Interius Biotherapeutics, Inc. | Mutated polypeptides, compositions comprising the same, and uses thereof |
| CA3268115A1 (en) | 2022-09-21 | 2024-03-28 | Sanofi Biotechnology | Humanized Anti-IL-1R3 Antibodies and Methods of Use |
| AU2024216919A1 (en) * | 2023-02-09 | 2025-08-07 | City Of Hope | Anti-il1rap antibodies and variants thereof |
| AU2024242538A1 (en) * | 2023-03-24 | 2025-10-30 | Paragon Therapeutics, Inc. | Fc fragments that bind fcrn and methods of use |
| WO2025126157A1 (en) * | 2023-12-15 | 2025-06-19 | Advesya | Anti-il-1rap binding domains and antibody-drug conjugates thereof |
| WO2025201513A1 (zh) * | 2024-03-29 | 2025-10-02 | 珠海丹序生物制药有限公司 | 抗il1rap抗体及其用途 |
| WO2026022232A1 (en) | 2024-07-24 | 2026-01-29 | Almirall, S.A. | Il-1rap inhibitor for treating or preventing hidradenitis suppurativa |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| SE459005B (sv) | 1985-07-12 | 1989-05-29 | Aake Rikard Lindahl | Saett att framstaella sfaeriska polymerpartiklar |
| PE64396A1 (es) | 1995-01-23 | 1997-01-28 | Hoffmann La Roche | Proteina accesoria del receptor de la interleucina 1 |
| CA2192782C (en) | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production of microspheres |
| US20030215453A1 (en) | 2002-05-14 | 2003-11-20 | Dedera Douglas A. | Methods of therapy and diagnosis using immunotargeting of cells expressing VpreB1 protein |
| US7960512B2 (en) | 2003-01-09 | 2011-06-14 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
| EP2003196A3 (en) | 2003-06-09 | 2009-01-07 | The Regents of the University of Michigan | Compositions and methods for treating and diagnosing cancer |
| GB0316294D0 (en) | 2003-07-11 | 2003-08-13 | Polytherics Ltd | Conjugated biological molecules and their preparation |
| ES2426817T3 (es) | 2004-08-04 | 2013-10-25 | Mentrik Biotech, Llc | Regiones Fc variantes |
| PL4160212T3 (pl) | 2008-01-15 | 2024-08-12 | The Board Of Trustees Of The Leland Stanford Junior University | Markery komórek macierzystych ostrej białaczki szpikowej |
| US20110044894A1 (en) | 2008-03-26 | 2011-02-24 | Cellerant Therapeutics, Inc. | Immunoglobulin and/or Toll-Like Receptor Proteins Associated with Myelogenous Haematological Proliferative Disorders and Uses Thereof |
| GB2472856B (en) | 2009-08-21 | 2012-07-11 | Cantargia Ab | IL1-RAP modulators and uses thereof |
| RU2597831C2 (ru) * | 2011-01-19 | 2016-09-20 | Кантаргия Аб | Анти-il1rap антитела и их применение при лечении людей |
| CN103077969B (zh) | 2011-10-26 | 2016-03-30 | 中国科学院微电子研究所 | 一种mos器件及其制造方法 |
| CA2990305A1 (en) | 2015-06-26 | 2016-12-29 | Mab Discovery Gmbh | Monoclonal anti-il-1racp antibodies |
| MA43164A (fr) | 2015-11-02 | 2018-09-12 | Janssen Pharmaceutica Nv | Anticorps anti-il1rap, molécules bispécifiques de liaison à un antigène liant il1rap et cd3 et leurs utilisations |
-
2014
- 2014-08-06 GB GBGB1413913.3A patent/GB201413913D0/en not_active Ceased
-
2015
- 2015-08-06 EP EP15747487.5A patent/EP3193926B1/en active Active
- 2015-08-06 BR BR112017002342-3A patent/BR112017002342A2/en not_active Application Discontinuation
- 2015-08-06 CA CA2955056A patent/CA2955056A1/en not_active Abandoned
- 2015-08-06 AU AU2015298852A patent/AU2015298852A1/en not_active Abandoned
- 2015-08-06 MX MX2017001599A patent/MX2017001599A/es unknown
- 2015-08-06 WO PCT/EP2015/068208 patent/WO2016020502A1/en not_active Ceased
- 2015-08-06 CN CN201580042011.9A patent/CN107074946B/zh active Active
- 2015-08-06 US US15/501,710 patent/US10100119B2/en active Active
- 2015-08-06 JP JP2017506267A patent/JP6827411B2/ja active Active
- 2015-08-06 KR KR1020177004417A patent/KR20170039685A/ko not_active Withdrawn
-
2018
- 2018-08-22 US US16/109,017 patent/US10562971B2/en active Active
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