JP6827411B2 - 新規の抗体及びその使用 - Google Patents

新規の抗体及びその使用 Download PDF

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JP6827411B2
JP6827411B2 JP2017506267A JP2017506267A JP6827411B2 JP 6827411 B2 JP6827411 B2 JP 6827411B2 JP 2017506267 A JP2017506267 A JP 2017506267A JP 2017506267 A JP2017506267 A JP 2017506267A JP 6827411 B2 JP6827411 B2 JP 6827411B2
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antibody
antigen
binding fragment
cancer
cells
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JP2017530692A (ja
JP2017530692A5 (enExample
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ヘレナ・オーゲスタム
トーアス・フィオレトス
マルクス・イェーロース
セシーリア・アン−クリスティーン・マルムボリ・ハーゲ
シェル・ショーストローム
アグネータ・スヴェードベリ
カーリン・ヴォン・ヴァーケンフェルト
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カンタージア アクチエボラーグ
カンタージア アクチエボラーグ
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
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    • A61K51/1027Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
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    • G01N33/5759Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
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    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
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    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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    • C07K2317/565Complementarity determining region [CDR]
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  • Proteomics, Peptides & Aminoacids (AREA)
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JP2017506267A 2014-08-06 2015-08-06 新規の抗体及びその使用 Active JP6827411B2 (ja)

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Application Number Priority Date Filing Date Title
GB1413913.3 2014-08-06
GBGB1413913.3A GB201413913D0 (en) 2014-08-06 2014-08-06 Novel antibodies and uses thereof
PCT/EP2015/068208 WO2016020502A1 (en) 2014-08-06 2015-08-06 Novel antibodies and uses thereof

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JP2017530692A JP2017530692A (ja) 2017-10-19
JP2017530692A5 JP2017530692A5 (enExample) 2018-08-30
JP6827411B2 true JP6827411B2 (ja) 2021-02-10

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US (2) US10100119B2 (enExample)
EP (1) EP3193926B1 (enExample)
JP (1) JP6827411B2 (enExample)
KR (1) KR20170039685A (enExample)
CN (1) CN107074946B (enExample)
AU (1) AU2015298852A1 (enExample)
BR (1) BR112017002342A2 (enExample)
CA (1) CA2955056A1 (enExample)
GB (1) GB201413913D0 (enExample)
MX (1) MX2017001599A (enExample)
WO (1) WO2016020502A1 (enExample)

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