CN107074946B - 新型抗体及其用途 - Google Patents
新型抗体及其用途 Download PDFInfo
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- CN107074946B CN107074946B CN201580042011.9A CN201580042011A CN107074946B CN 107074946 B CN107074946 B CN 107074946B CN 201580042011 A CN201580042011 A CN 201580042011A CN 107074946 B CN107074946 B CN 107074946B
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- antibody
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C—CHEMISTRY; METALLURGY
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- C07K2317/52—Constant or Fc region; Isotype
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
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- G01N2333/7155—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1413913.3A GB201413913D0 (en) | 2014-08-06 | 2014-08-06 | Novel antibodies and uses thereof |
| GB1413913.3 | 2014-08-06 | ||
| PCT/EP2015/068208 WO2016020502A1 (en) | 2014-08-06 | 2015-08-06 | Novel antibodies and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107074946A CN107074946A (zh) | 2017-08-18 |
| CN107074946B true CN107074946B (zh) | 2022-03-22 |
Family
ID=51587804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580042011.9A Active CN107074946B (zh) | 2014-08-06 | 2015-08-06 | 新型抗体及其用途 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10100119B2 (enExample) |
| EP (1) | EP3193926B1 (enExample) |
| JP (1) | JP6827411B2 (enExample) |
| KR (1) | KR20170039685A (enExample) |
| CN (1) | CN107074946B (enExample) |
| AU (1) | AU2015298852A1 (enExample) |
| BR (1) | BR112017002342A2 (enExample) |
| CA (1) | CA2955056A1 (enExample) |
| GB (1) | GB201413913D0 (enExample) |
| MX (1) | MX2017001599A (enExample) |
| WO (1) | WO2016020502A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2472856B (en) | 2009-08-21 | 2012-07-11 | Cantargia Ab | IL1-RAP modulators and uses thereof |
| EP3508498A1 (en) | 2011-01-19 | 2019-07-10 | Cantargia AB | Novel agents and uses thereof |
| GB201403875D0 (en) | 2014-03-05 | 2014-04-16 | Cantargia Ab | Novel antibodies and uses thereof |
| CN107109494B (zh) | 2014-11-10 | 2023-10-27 | 豪夫迈·罗氏有限公司 | Il-33介导型疾病的治疗方法和诊断方法 |
| CA2960297A1 (en) | 2014-11-10 | 2016-05-19 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
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| EP3193926A1 (en) | 2017-07-26 |
| JP6827411B2 (ja) | 2021-02-10 |
| GB201413913D0 (en) | 2014-09-17 |
| EP3193926B1 (en) | 2022-10-05 |
| BR112017002342A2 (pt) | 2018-01-16 |
| WO2016020502A1 (en) | 2016-02-11 |
| AU2015298852A1 (en) | 2017-02-02 |
| KR20170039685A (ko) | 2017-04-11 |
| US20180355049A1 (en) | 2018-12-13 |
| CN107074946A (zh) | 2017-08-18 |
| US10100119B2 (en) | 2018-10-16 |
| JP2017530692A (ja) | 2017-10-19 |
| US20180044425A1 (en) | 2018-02-15 |
| CA2955056A1 (en) | 2016-02-11 |
| MX2017001599A (es) | 2017-05-23 |
| US10562971B2 (en) | 2020-02-18 |
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