BR112017002342A2 - novos anticorpos e usos dos mesmos - Google Patents

novos anticorpos e usos dos mesmos

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Publication number
BR112017002342A2
BR112017002342A2 BR112017002342A BR112017002342A BR112017002342A2 BR 112017002342 A2 BR112017002342 A2 BR 112017002342A2 BR 112017002342 A BR112017002342 A BR 112017002342A BR 112017002342 A BR112017002342 A BR 112017002342A BR 112017002342 A2 BR112017002342 A2 BR 112017002342A2
Authority
BR
Brazil
Prior art keywords
antigen binding
antibody
new antibodies
binding fragment
human
Prior art date
Application number
BR112017002342A
Other languages
English (en)
Inventor
Svedberg Agneta
Ann-Christin Malmborg Hager Cecilia
ÅGERSTAM Helena
Von Wachenfeldt Karin
SJÖSTRÖM Kjell
Järås Marcus
Fioretos Thoas
Original Assignee
Cantargia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cantargia Ab filed Critical Cantargia Ab
Publication of BR112017002342A2 publication Critical patent/BR112017002342A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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Abstract

a presente invenção refere-se a um anticorpo ou um fragmento de ligação de antígeno do mesmo com especificidade de ligação para proteína acessória de receptor de interleucina-1 humana (il1rap) em que o anticorpo ou fragmento de ligação de antígeno tem capacidade de inibir to domínio 3 de rap de il1 humano. a invenção fornece adicionalmente o uso de tais anticorpos ou fragmentos de ligação de um antígeno no tratamento e/ou diagnóstico de cânceres, tais como, leucemias e melanoma.
BR112017002342A 2014-08-06 2015-08-06 novos anticorpos e usos dos mesmos BR112017002342A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1413913.3A GB201413913D0 (en) 2014-08-06 2014-08-06 Novel antibodies and uses thereof
PCT/EP2015/068208 WO2016020502A1 (en) 2014-08-06 2015-08-06 Novel antibodies and uses thereof

Publications (1)

Publication Number Publication Date
BR112017002342A2 true BR112017002342A2 (pt) 2018-01-16

Family

ID=51587804

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017002342A BR112017002342A2 (pt) 2014-08-06 2015-08-06 novos anticorpos e usos dos mesmos

Country Status (11)

Country Link
US (2) US10100119B2 (pt)
EP (1) EP3193926B1 (pt)
JP (1) JP6827411B2 (pt)
KR (1) KR20170039685A (pt)
CN (1) CN107074946B (pt)
AU (1) AU2015298852A1 (pt)
BR (1) BR112017002342A2 (pt)
CA (1) CA2955056A1 (pt)
GB (1) GB201413913D0 (pt)
MX (1) MX2017001599A (pt)
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MX2017001599A (es) 2017-05-23
JP2017530692A (ja) 2017-10-19
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US10562971B2 (en) 2020-02-18
KR20170039685A (ko) 2017-04-11
CN107074946A (zh) 2017-08-18
WO2016020502A1 (en) 2016-02-11
EP3193926B1 (en) 2022-10-05
US20180355049A1 (en) 2018-12-13
US10100119B2 (en) 2018-10-16
AU2015298852A1 (en) 2017-02-02
EP3193926A1 (en) 2017-07-26
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US20180044425A1 (en) 2018-02-15
CA2955056A1 (en) 2016-02-11

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