JP2017530373A5 - - Google Patents
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- Publication number
- JP2017530373A5 JP2017530373A5 JP2017533721A JP2017533721A JP2017530373A5 JP 2017530373 A5 JP2017530373 A5 JP 2017530373A5 JP 2017533721 A JP2017533721 A JP 2017533721A JP 2017533721 A JP2017533721 A JP 2017533721A JP 2017530373 A5 JP2017530373 A5 JP 2017530373A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- soluble
- sample
- misfolded
- soluble misfolded
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021081274A JP7104943B2 (ja) | 2014-09-11 | 2021-05-12 | ミスフォールディングタンパク質の検出 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462049306P | 2014-09-11 | 2014-09-11 | |
| US62/049,306 | 2014-09-11 | ||
| PCT/US2015/049844 WO2016040907A1 (en) | 2014-09-11 | 2015-09-11 | Detection of misfolded proteins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021081274A Division JP7104943B2 (ja) | 2014-09-11 | 2021-05-12 | ミスフォールディングタンパク質の検出 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530373A JP2017530373A (ja) | 2017-10-12 |
| JP2017530373A5 true JP2017530373A5 (enExample) | 2018-10-25 |
| JP6980953B2 JP6980953B2 (ja) | 2021-12-15 |
Family
ID=55454515
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017533721A Active JP6980953B2 (ja) | 2014-09-11 | 2015-09-11 | ミスフォールディングタンパク質の検出 |
| JP2021081274A Active JP7104943B2 (ja) | 2014-09-11 | 2021-05-12 | ミスフォールディングタンパク質の検出 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021081274A Active JP7104943B2 (ja) | 2014-09-11 | 2021-05-12 | ミスフォールディングタンパク質の検出 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20160077112A1 (enExample) |
| EP (2) | EP3191599B1 (enExample) |
| JP (2) | JP6980953B2 (enExample) |
| KR (1) | KR102448128B1 (enExample) |
| CN (1) | CN107208125A (enExample) |
| AU (1) | AU2015314783B2 (enExample) |
| BR (1) | BR112017004899A2 (enExample) |
| CA (1) | CA2960830C (enExample) |
| ES (1) | ES2953855T3 (enExample) |
| HR (1) | HRP20231232T1 (enExample) |
| IL (2) | IL251052B (enExample) |
| MX (1) | MX2017003269A (enExample) |
| PL (1) | PL3191599T3 (enExample) |
| SG (2) | SG10202008464UA (enExample) |
| WO (1) | WO2016040907A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10989718B2 (en) | 2014-09-11 | 2021-04-27 | Amprion, Inc. | Detection of misfolded alpha synuclein protein |
| US11079396B2 (en) * | 2019-09-04 | 2021-08-03 | Amprion, Inc. | Alpha-synuclein detection using beads |
| GB201611840D0 (en) | 2016-07-07 | 2016-08-24 | Univ Court Of The Univ Of Edinburgh The | Alpha-synuclein detection assay |
| BR112019016374A2 (pt) | 2017-02-17 | 2020-04-07 | Bristol-Myers Squibb Company | anticorpos para alfa-sinucleína e usos dos mesmos |
| CN110869763B (zh) | 2017-05-16 | 2022-07-29 | 安培里翁公司 | 错误折叠tau蛋白质的检测 |
| CA3074914A1 (en) | 2017-10-02 | 2019-04-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Assay for the detection of alpha-synuclein seeding activity associated with synucleinopathies |
| GB201720975D0 (en) | 2017-12-15 | 2018-01-31 | Ucb Biopharma Sprl | Anti-alpha synuclein antibodies |
| GB201720970D0 (en) | 2017-12-15 | 2018-01-31 | Ucb Biopharma Sprl | Antibodies |
| US20200309796A1 (en) * | 2017-12-21 | 2020-10-01 | H. Lundbeck A/S | Assay, method and treatment of alpha-synucleinopathies |
| CN108088816A (zh) * | 2018-01-23 | 2018-05-29 | 深圳市国赛生物技术有限公司 | 小型特定蛋白分析仪 |
| GB201803553D0 (en) | 2018-03-06 | 2018-04-18 | Univ Newcastle | Detection of pathological protein aggregation |
| US20190353669A1 (en) * | 2018-05-16 | 2019-11-21 | Amprion, Inc. | Detection of Brain Injury or Neurological Disease using Tau Protein |
| US12437843B2 (en) * | 2018-09-21 | 2025-10-07 | Gdm Holding Llc | Predicting protein structures using geometry neural networks that estimate similarity between predicted protein structures and actual protein structures |
| JP7376040B2 (ja) * | 2019-09-03 | 2023-11-08 | 国立大学法人京都工芸繊維大学 | 神経変性疾患におけるバイオマーカー分子の検出方法 |
| KR102277871B1 (ko) * | 2019-12-17 | 2021-07-15 | 원광대학교산학협력단 | 소변의 알파-씨누클레인 중합체 측정에 의한 파킨슨병 진단 정보의 수집방법 및 그 키트 |
| WO2021198098A1 (en) | 2020-04-03 | 2021-10-07 | Universität Zürich | Improved method of detecting biomarkers in a biological sample |
| MX2022014319A (es) * | 2020-05-18 | 2023-02-27 | Amprion Inc | Sustratos de alfa-sinucleína y métodos para la fabricación y el uso de los mismos. |
| WO2022105923A1 (zh) * | 2020-11-21 | 2022-05-27 | 浙江数问生物技术有限公司 | 用于检测生物样本中的错误折叠蛋白质的装置和方法 |
| US20240192230A1 (en) * | 2021-04-15 | 2024-06-13 | The Brigham And Women’S Hospital, Inc. | Digital Protein Misfolding Assays |
| CN114199875B (zh) * | 2022-02-18 | 2022-05-20 | 之江实验室 | 一种蛋白质多聚体是否可作为力缓冲剂的判断方法及装置 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1712920T3 (da) | 2000-07-07 | 2009-05-11 | Merck Serono Sa | Tidlig diagnose af konformationelle sygdomme |
| US20030027210A1 (en) * | 2001-01-03 | 2003-02-06 | Daniel Benjamin | Alpha synuclein aggregation assays |
| GB0203446D0 (en) * | 2002-02-14 | 2002-04-03 | Univ Lancaster | Detection and/or monitoring of synuclein-related diseases |
| EP1820806A1 (en) * | 2006-02-16 | 2007-08-22 | Crossbeta Biosciences B.V. | Affinity regions |
| ATE528649T1 (de) * | 2005-02-15 | 2011-10-15 | Adlyfe Inc | Verfahren zum nachweis falsch gefalteter proteine und prionen |
| JP2009537153A (ja) * | 2006-05-19 | 2009-10-29 | アルニラム ファーマシューティカルズ， インコーポレイテッド | ＡｈａのＲＮＡｉ調節およびその治療上の使用 |
| WO2008030973A2 (en) * | 2006-09-06 | 2008-03-13 | The Board Of Regents Of The University Of Texas System | Methods and compositions for the detection of protein folding disorders |
| JP2010043865A (ja) * | 2006-12-12 | 2010-02-25 | Olympus Corp | 異常型プリオンの検出方法 |
| CN102666577A (zh) * | 2009-11-24 | 2012-09-12 | 前体生物药物股份公司 | 诊断阿尔茨海默病或轻度认知损害的新的诊断方法 |
| US9133343B2 (en) * | 2009-11-30 | 2015-09-15 | Enzo Biochem, Inc. | Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications |
| WO2012099884A1 (en) * | 2011-01-18 | 2012-07-26 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for amplification and detection of prions |
| US9534044B2 (en) * | 2013-02-28 | 2017-01-03 | United Arab Emirates University | Alpha-synuclein antibodies and uses thereof |
| WO2016040903A1 (en) * | 2014-09-11 | 2016-03-17 | Board Of Regents Of The University Of Texas System | Detection of misfolded amyloid beta protein |
-
2015
- 2015-09-11 JP JP2017533721A patent/JP6980953B2/ja active Active
- 2015-09-11 SG SG10202008464UA patent/SG10202008464UA/en unknown
- 2015-09-11 BR BR112017004899A patent/BR112017004899A2/pt not_active Application Discontinuation
- 2015-09-11 CN CN201580058606.3A patent/CN107208125A/zh active Pending
- 2015-09-11 ES ES15839278T patent/ES2953855T3/es active Active
- 2015-09-11 MX MX2017003269A patent/MX2017003269A/es unknown
- 2015-09-11 KR KR1020177009707A patent/KR102448128B1/ko active Active
- 2015-09-11 WO PCT/US2015/049844 patent/WO2016040907A1/en not_active Ceased
- 2015-09-11 CA CA2960830A patent/CA2960830C/en active Active
- 2015-09-11 EP EP15839278.7A patent/EP3191599B1/en active Active
- 2015-09-11 US US14/852,478 patent/US20160077112A1/en not_active Abandoned
- 2015-09-11 AU AU2015314783A patent/AU2015314783B2/en active Active
- 2015-09-11 SG SG11201701953RA patent/SG11201701953RA/en unknown
- 2015-09-11 HR HRP20231232TT patent/HRP20231232T1/hr unknown
- 2015-09-11 EP EP23189057.5A patent/EP4292654A3/en active Pending
- 2015-09-11 PL PL15839278.7T patent/PL3191599T3/pl unknown
-
2017
- 2017-03-09 IL IL251052A patent/IL251052B/en unknown
-
2021
- 2021-05-12 JP JP2021081274A patent/JP7104943B2/ja active Active
-
2022
- 2022-03-30 IL IL291809A patent/IL291809B2/en unknown
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