JP2010514805A5 - - Google Patents

Download PDF

Info

Publication number
JP2010514805A5
JP2010514805A5 JP2009544308A JP2009544308A JP2010514805A5 JP 2010514805 A5 JP2010514805 A5 JP 2010514805A5 JP 2009544308 A JP2009544308 A JP 2009544308A JP 2009544308 A JP2009544308 A JP 2009544308A JP 2010514805 A5 JP2010514805 A5 JP 2010514805A5
Authority
JP
Japan
Prior art keywords
znt8
fragment
antibody
individual
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009544308A
Other languages
English (en)
Japanese (ja)
Other versions
JP5694668B2 (ja
JP2010514805A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/089125 external-priority patent/WO2008083331A2/en
Publication of JP2010514805A publication Critical patent/JP2010514805A/ja
Publication of JP2010514805A5 publication Critical patent/JP2010514805A5/ja
Application granted granted Critical
Publication of JP5694668B2 publication Critical patent/JP5694668B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009544308A 2006-12-29 2007-12-28 自己免疫疾患の診断上および治療上の標的ならびにその用途 Active JP5694668B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88281506P 2006-12-29 2006-12-29
US60/882,815 2006-12-29
PCT/US2007/089125 WO2008083331A2 (en) 2006-12-29 2007-12-28 Diagnostic and therapeutic target for autoimmune diseases and uses thereof

Publications (3)

Publication Number Publication Date
JP2010514805A JP2010514805A (ja) 2010-05-06
JP2010514805A5 true JP2010514805A5 (enExample) 2010-11-25
JP5694668B2 JP5694668B2 (ja) 2015-04-01

Family

ID=39589229

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009544308A Active JP5694668B2 (ja) 2006-12-29 2007-12-28 自己免疫疾患の診断上および治療上の標的ならびにその用途

Country Status (8)

Country Link
US (1) US9023984B2 (enExample)
EP (1) EP2118309B1 (enExample)
JP (1) JP5694668B2 (enExample)
CN (1) CN101646781B (enExample)
DK (1) DK2118309T3 (enExample)
ES (1) ES2533566T3 (enExample)
PL (1) PL2118309T3 (enExample)
WO (1) WO2008083331A2 (enExample)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112009005237T5 (de) * 2009-09-18 2012-09-06 The Regents Of The University Of California Verfahren zum nachweisen von autodigestion
CN102060910B (zh) * 2010-11-12 2012-11-21 中国人民解放军第三军医大学 锌转运蛋白8的hla-a*0201限制性ctl表位及其应用
CN107320734A (zh) 2011-04-29 2017-11-07 西莱克塔生物科技公司 从合成纳米载体中控制释放免疫抑制剂
WO2013061353A1 (en) 2011-10-26 2013-05-02 Universita' Degli Studi Di Sassari Use of mycobacterium avium paratuberculosis peptides to diagnose type 1 diabetes
CN103177198B (zh) * 2011-12-26 2016-11-23 深圳华大基因科技服务有限公司 一种蛋白质鉴定方法
EP2836845B1 (en) 2012-04-13 2018-05-09 DiabetOmics, Inc. Maternal biomarkers for gestational diabetes
CN102967704B (zh) * 2012-11-26 2014-05-14 深圳市伯劳特生物制品有限公司 一种用于糖尿病自身抗体6项联检试剂盒
US20160025744A1 (en) * 2013-03-14 2016-01-28 The Board Of Trustees Of The Leland Stanford Junior University Plasmonic substrate for multiplex assessment of type 1 diabetes
CN105307641A (zh) 2013-05-03 2016-02-03 西莱克塔生物科技公司 用于降低不期望体液免疫应答的给药组合
AU2014278178B2 (en) * 2013-06-11 2021-01-21 President And Fellows Of Harvard College SC-beta cells and compositions and methods for generating the same
SMT202000384T1 (it) * 2014-06-04 2020-09-10 Diamyd Medical Ab Acido glutammico decarbossilasi(gad)per l'uso nel trattamento di una malattia autoimmune
US12605432B2 (en) 2014-06-04 2026-04-21 Diamyd Medical Ab Combinations for antigen based therapy
KR101482908B1 (ko) 2014-07-25 2015-01-15 충남대학교산학협력단 간질중첩증 진단용 바이오마커 조성물
EA201790551A1 (ru) 2014-09-07 2017-07-31 Селекта Байосайенсиз, Инк. Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору
CN107614678B (zh) 2014-12-18 2021-04-30 哈佛学院校长同事会 干细胞来源的β细胞的产生方法及其使用方法
ES2985135T3 (es) 2014-12-18 2024-11-04 Harvard College Procedimientos para generar células ß derivadas de células madre y usos de las mismas
US10443042B2 (en) 2014-12-18 2019-10-15 President And Fellows Of Harvard College Serum-free in vitro directed differentiation protocol for generating stem cell-derived beta cells and uses thereof
GB201510056D0 (en) * 2015-06-10 2015-07-22 King S College London Multi-peptide composition
US10542961B2 (en) 2015-06-15 2020-01-28 The Research Foundation For The State University Of New York System and method for infrasonic cardiac monitoring
US20170082619A1 (en) 2015-09-23 2017-03-23 One Lambda, Inc. Methods of Detecting Alloantibodies Using HLA and Non-HLA Antigens
CN106084043B (zh) * 2016-02-17 2018-03-02 张梅 一种ZnT8特异性单链抗体scFv‑C22及其应用
CN106084051B (zh) * 2016-02-17 2018-03-02 张梅 一种ZnT8特异性单链抗体scFv‑C27及其应用
US11016085B2 (en) 2016-04-25 2021-05-25 The Johns Hopkins University ZNT8 assays for drug development and pharmaceutical compositions
CN106771233A (zh) * 2016-12-05 2017-05-31 上海良润生物医药科技有限公司 ZnT8A自身抗体检测试剂盒
EP4599848A3 (en) 2017-03-11 2025-12-03 Cartesian Therapeutics, Inc. Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant
CN111316099A (zh) * 2017-07-12 2020-06-19 约翰霍普金斯大学 用于1型糖尿病诊断的基于脂蛋白体的znt8自身抗原
WO2019099725A1 (en) 2017-11-15 2019-05-23 Semma Therapeutics, Inc. Islet cell manufacturing compositions and methods of use
CN108414766A (zh) * 2018-01-29 2018-08-17 上海良润生物医药科技有限公司 用于定量检测糖尿病自身抗体的试剂盒及其应用
WO2019169351A1 (en) 2018-03-02 2019-09-06 Semma Therapeutics, Inc. Methods of enhancing stem cell differentiation into beta cells
EP3833365A4 (en) 2018-08-10 2022-05-11 Vertex Pharmaceuticals Incorporated Stem cell derived islet differentiation
WO2020037174A1 (en) 2018-08-16 2020-02-20 The Johns Hopkins University Antibodies to human znt8
CN109628462B (zh) * 2018-12-13 2021-02-19 宁波大学 一种水稻根系伸长控制基因OsKSR7及编码的蛋白质
CN109734793B (zh) * 2019-03-14 2022-12-02 深圳市药品检验研究院(深圳市医疗器械检测中心) 一种ZnT8重组蛋白及其制备方法和应用
US12553041B2 (en) 2019-06-04 2026-02-17 Cartesian Therapeutics Inc. Formulations and doses of pegylated uricase
US12366570B2 (en) 2019-10-01 2025-07-22 The Johns Hopkins University Cell-based ZNT8 assay
CN111579791A (zh) * 2020-04-30 2020-08-25 江苏省人民医院(南京医科大学第一附属医院) 一种锌转运体8胰岛自身抗体的电化学发光检测试剂盒
CN113999841A (zh) * 2021-09-16 2022-02-01 江苏省人民医院(南京医科大学第一附属医院) 蛋白质支架oval100及其在放射配体法中的应用
CN116589589B (zh) * 2023-03-24 2024-10-22 深圳市昭蓝生物科技有限公司 糖尿病检测的质控品及其制备方法和用途
CN117031014A (zh) * 2023-08-14 2023-11-10 陕西脉元生物科技有限公司 抗matr3自身抗体的试剂在制备检测神经系统自身免疫疾病的产品中的应用及试剂盒
WO2026096993A1 (en) * 2024-11-01 2026-05-07 The Regents Of The University Of Colorado, A Body Corporate Configurations and methods for detecting insulin autoantibodies by enzyme-linked immunosorbent assay
CN120714599B (zh) * 2025-08-28 2025-10-31 江苏集萃医工交叉技术研究所有限公司 一种血清bicc1天然蛋白的高效提取保存方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
CA2043472A1 (en) 1990-06-04 1991-12-05 Mitsutaka Miyabayashi Electrode for secondary battery
US5820866A (en) 1994-03-04 1998-10-13 National Jewish Center For Immunology And Respiratory Medicine Product and process for T cell regulation
WO2001094409A2 (en) 2000-06-07 2001-12-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of pancreatic cancer
FR2847263B1 (fr) 2002-11-18 2006-01-13 Commissariat Energie Atomique Polynucleotide specifique de la cellule pancreatique beta des ilots de langerhans

Similar Documents

Publication Publication Date Title
CA3109607C (en) Methods and reagents for diagnosis of sars-cov-2 infection
JP7815199B2 (ja) 腎疾患及び歯周疾患を検出及び診断するための方法及び組成物
JP6009938B2 (ja) プロカルシトニンの検出のためのイムノアッセイ
CN104470942B (zh) 生物标志物
JP2017502253A5 (enExample)
JP2012509295A5 (enExample)
JP2010528261A5 (enExample)
JP2013539032A5 (enExample)
RU2016116766A (ru) Диагностика и лечение синдрома раздраженного кишечника и воспалительного заболевания кишечника
JP2023065484A (ja) 新規タウ種
JP2011514156A5 (enExample)
RU2013158334A (ru) Средства и способы диагностики и лечения рассеянного склероза
ES2902888T3 (es) Proteína Rep mejorada para su uso en un ensayo diagnóstico
ES2764225T3 (es) Inmunoensayo para la detección de cromogramina A
WO2014161875A1 (en) METHOD FOR DETECTING Aβ-SPECIFIC ANTIBODIES IN A BIOLOGICAL SAMPLE
JP2007533985A5 (enExample)
US9068993B2 (en) Diagnostic assays and methods of use for detection of filarial infection
US8338566B2 (en) Characterization of BBK07 antigen of Borrelia burgdorferi and methods of use
ES3059953T3 (en) Autoantibodies as biomarker of paraneoplastic encephalitis associated with testicular cancer
TWI397687B (zh) 腎病變相關之生物標記的應用及其中所使用的套組
RU2011144030A (ru) Диагностика индуцируемых глютеном аутоиммунных заболеваний
JP2007514655A5 (enExample)
JP2011528799A5 (enExample)
CA2771954A1 (en) Pneumonia biomarkers
EP3069146A1 (en) Biomarker for cardiac disorders