JP2010514805A5 - - Google Patents
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- Publication number
- JP2010514805A5 JP2010514805A5 JP2009544308A JP2009544308A JP2010514805A5 JP 2010514805 A5 JP2010514805 A5 JP 2010514805A5 JP 2009544308 A JP2009544308 A JP 2009544308A JP 2009544308 A JP2009544308 A JP 2009544308A JP 2010514805 A5 JP2010514805 A5 JP 2010514805A5
- Authority
- JP
- Japan
- Prior art keywords
- znt8
- fragment
- antibody
- individual
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88281506P | 2006-12-29 | 2006-12-29 | |
| US60/882,815 | 2006-12-29 | ||
| PCT/US2007/089125 WO2008083331A2 (en) | 2006-12-29 | 2007-12-28 | Diagnostic and therapeutic target for autoimmune diseases and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010514805A JP2010514805A (ja) | 2010-05-06 |
| JP2010514805A5 true JP2010514805A5 (enExample) | 2010-11-25 |
| JP5694668B2 JP5694668B2 (ja) | 2015-04-01 |
Family
ID=39589229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009544308A Active JP5694668B2 (ja) | 2006-12-29 | 2007-12-28 | 自己免疫疾患の診断上および治療上の標的ならびにその用途 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9023984B2 (enExample) |
| EP (1) | EP2118309B1 (enExample) |
| JP (1) | JP5694668B2 (enExample) |
| CN (1) | CN101646781B (enExample) |
| DK (1) | DK2118309T3 (enExample) |
| ES (1) | ES2533566T3 (enExample) |
| PL (1) | PL2118309T3 (enExample) |
| WO (1) | WO2008083331A2 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2774411A1 (en) * | 2009-09-18 | 2011-03-24 | Geert W. Schmid-Schonbein | Methods for detecting autodigestion |
| CN102060910B (zh) * | 2010-11-12 | 2012-11-21 | 中国人民解放军第三军医大学 | 锌转运蛋白8的hla-a＊0201限制性ctl表位及其应用 |
| KR20140041505A (ko) * | 2011-04-29 | 2014-04-04 | 셀렉타 바이오사이언시즈, 인크. | 조절 b 세포 유도를 위한 관용원성 합성 나노운반체 |
| US20140271701A1 (en) | 2011-10-26 | 2014-09-18 | Universita' Degli Studi Di Sassari | Use of mycobacterium avium paratuberculosis peptides to diagnose type 1 diabetes |
| CN103177198B (zh) * | 2011-12-26 | 2016-11-23 | 深圳华大基因科技服务有限公司 | 一种蛋白质鉴定方法 |
| IN2014DN09410A (enExample) | 2012-04-13 | 2015-07-17 | Diabetomics Llc | |
| CN102967704B (zh) * | 2012-11-26 | 2014-05-14 | 深圳市伯劳特生物制品有限公司 | 一种用于糖尿病自身抗体6项联检试剂盒 |
| WO2014160175A1 (en) * | 2013-03-14 | 2014-10-02 | The Board Of Trustees Of The Leland Stanford Junior University | Plasmonic substrate for multiplex assessment of type 1 diabetes |
| BR112015027291A8 (pt) | 2013-05-03 | 2019-12-24 | Selecta Biosciences Inc | uso de um imunossupressor que têm uma vida eficaz farmacodinâmica especificada e composição compreendendo o referido imunossupressor |
| KR102580225B1 (ko) | 2013-06-11 | 2023-09-20 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | SC-β 세포 및 조성물 그리고 그 생성 방법 |
| US12605432B2 (en) | 2014-06-04 | 2026-04-21 | Diamyd Medical Ab | Combinations for antigen based therapy |
| DK3151853T3 (da) * | 2014-06-04 | 2020-07-27 | Diamyd Medical Ab | Glutaminsyre-decarboxylase (GAD) til anvendelse ved behandling af en autoimmun sygdom |
| KR101482908B1 (ko) | 2014-07-25 | 2015-01-15 | 충남대학교산학협력단 | 간질중첩증 진단용 바이오마커 조성물 |
| WO2016037164A1 (en) | 2014-09-07 | 2016-03-10 | Selecta Biosciences, Inc. | Methods and compositions for attenuating gene expression modulating anti-viral transfer vector immune responses |
| ES2985135T3 (es) | 2014-12-18 | 2024-11-04 | Harvard College | Procedimientos para generar células ß derivadas de células madre y usos de las mismas |
| WO2016100930A1 (en) | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | Methods for generating stem cell-derived b cells and methods of use thereof |
| WO2016100898A1 (en) | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | Serum-free in vitro directed differentiation protocol for generating stem cell-derived b cells and uses thereof |
| GB201510056D0 (en) * | 2015-06-10 | 2015-07-22 | King S College London | Multi-peptide composition |
| US10542961B2 (en) | 2015-06-15 | 2020-01-28 | The Research Foundation For The State University Of New York | System and method for infrasonic cardiac monitoring |
| US20170082619A1 (en) | 2015-09-23 | 2017-03-23 | One Lambda, Inc. | Methods of Detecting Alloantibodies Using HLA and Non-HLA Antigens |
| CN106084051B (zh) * | 2016-02-17 | 2018-03-02 | 张梅 | 一种ZnT8特异性单链抗体scFv‑C27及其应用 |
| CN106084043B (zh) * | 2016-02-17 | 2018-03-02 | 张梅 | 一种ZnT8特异性单链抗体scFv‑C22及其应用 |
| US11016085B2 (en) | 2016-04-25 | 2021-05-25 | The Johns Hopkins University | ZNT8 assays for drug development and pharmaceutical compositions |
| CN106771233A (zh) * | 2016-12-05 | 2017-05-31 | 上海良润生物医药科技有限公司 | ZnT8A自身抗体检测试剂盒 |
| KR102753928B1 (ko) | 2017-03-11 | 2025-01-14 | 셀렉타 바이오사이언시즈, 인크. | 항염증제, 및 면역억제제를 포함하는 합성 나노담체를 사용한 조합 치료와 관련된 방법 및 조성물 |
| EP3652540A4 (en) * | 2017-07-12 | 2021-04-07 | The Johns Hopkins University | PROTEOLIPOSOME BASED ZNT-8 SELF-ANTIGENT FOR THE DIAGNOSIS OF TYPE 1 DIABETES |
| CN118497104A (zh) | 2017-11-15 | 2024-08-16 | 沃泰克斯药物股份有限公司 | 胰岛细胞制备性组合物和使用方法 |
| CN108414766A (zh) * | 2018-01-29 | 2018-08-17 | 上海良润生物医药科技有限公司 | 用于定量检测糖尿病自身抗体的试剂盒及其应用 |
| EP3833365A4 (en) | 2018-08-10 | 2022-05-11 | Vertex Pharmaceuticals Incorporated | Stem cell derived islet differentiation |
| WO2020037174A1 (en) | 2018-08-16 | 2020-02-20 | The Johns Hopkins University | Antibodies to human znt8 |
| CN109628462B (zh) * | 2018-12-13 | 2021-02-19 | 宁波大学 | 一种水稻根系伸长控制基因OsKSR7及编码的蛋白质 |
| CN109734793B (zh) * | 2019-03-14 | 2022-12-02 | 深圳市药品检验研究院（深圳市医疗器械检测中心） | 一种ZnT8重组蛋白及其制备方法和应用 |
| EP3980784A1 (en) | 2019-06-04 | 2022-04-13 | Selecta Biosciences, Inc. | Formulations and doses of pegylated uricase |
| US12366570B2 (en) | 2019-10-01 | 2025-07-22 | The Johns Hopkins University | Cell-based ZNT8 assay |
| CN111579791A (zh) * | 2020-04-30 | 2020-08-25 | 江苏省人民医院（南京医科大学第一附属医院） | 一种锌转运体8胰岛自身抗体的电化学发光检测试剂盒 |
| CN113999841A (zh) * | 2021-09-16 | 2022-02-01 | 江苏省人民医院（南京医科大学第一附属医院） | 蛋白质支架oval100及其在放射配体法中的应用 |
| CN116589589B (zh) * | 2023-03-24 | 2024-10-22 | 深圳市昭蓝生物科技有限公司 | 糖尿病检测的质控品及其制备方法和用途 |
| CN117031014A (zh) * | 2023-08-14 | 2023-11-10 | 陕西脉元生物科技有限公司 | 抗matr3自身抗体的试剂在制备检测神经系统自身免疫疾病的产品中的应用及试剂盒 |
| CN120714599B (zh) * | 2025-08-28 | 2025-10-31 | 江苏集萃医工交叉技术研究所有限公司 | 一种血清bicc1天然蛋白的高效提取保存方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| CA2043472A1 (en) | 1990-06-04 | 1991-12-05 | Mitsutaka Miyabayashi | Electrode for secondary battery |
| US5820866A (en) | 1994-03-04 | 1998-10-13 | National Jewish Center For Immunology And Respiratory Medicine | Product and process for T cell regulation |
| WO2001094409A2 (en) | 2000-06-07 | 2001-12-13 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of pancreatic cancer |
| FR2847263B1 (fr) * | 2002-11-18 | 2006-01-13 | Commissariat Energie Atomique | Polynucleotide specifique de la cellule pancreatique beta des ilots de langerhans |
-
2007
- 2007-12-28 ES ES07870089.5T patent/ES2533566T3/es active Active
- 2007-12-28 WO PCT/US2007/089125 patent/WO2008083331A2/en not_active Ceased
- 2007-12-28 US US12/521,022 patent/US9023984B2/en active Active
- 2007-12-28 PL PL07870089T patent/PL2118309T3/pl unknown
- 2007-12-28 CN CN200780051859.3A patent/CN101646781B/zh active Active
- 2007-12-28 EP EP07870089.5A patent/EP2118309B1/en active Active
- 2007-12-28 DK DK07870089T patent/DK2118309T3/en active
- 2007-12-28 JP JP2009544308A patent/JP5694668B2/ja active Active
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