JP2011514156A5 - - Google Patents
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- Publication number
- JP2011514156A5 JP2011514156A5 JP2010547586A JP2010547586A JP2011514156A5 JP 2011514156 A5 JP2011514156 A5 JP 2011514156A5 JP 2010547586 A JP2010547586 A JP 2010547586A JP 2010547586 A JP2010547586 A JP 2010547586A JP 2011514156 A5 JP2011514156 A5 JP 2011514156A5
- Authority
- JP
- Japan
- Prior art keywords
- anp
- acd
- level
- transplant rejection
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 31
- 206010019315 Heart transplant rejection Diseases 0.000 claims 28
- 239000012634 fragment Substances 0.000 claims 28
- 208000019693 Lung disease Diseases 0.000 claims 19
- 238000012544 monitoring process Methods 0.000 claims 19
- 239000011230 binding agent Substances 0.000 claims 18
- 230000001154 acute effect Effects 0.000 claims 17
- 239000000427 antigen Substances 0.000 claims 16
- 102000036639 antigens Human genes 0.000 claims 16
- 108091007433 antigens Proteins 0.000 claims 16
- 238000003556 assay Methods 0.000 claims 16
- 239000012472 biological sample Substances 0.000 claims 12
- 208000013875 Heart injury Diseases 0.000 claims 11
- 208000004852 Lung Injury Diseases 0.000 claims 10
- 239000000523 sample Substances 0.000 claims 9
- 206010069363 Traumatic lung injury Diseases 0.000 claims 7
- 231100000515 lung injury Toxicity 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 7
- 238000005259 measurement Methods 0.000 claims 6
- 238000000672 surface-enhanced laser desorption--ionisation Methods 0.000 claims 6
- 238000004949 mass spectrometry Methods 0.000 claims 5
- 206010052779 Transplant rejections Diseases 0.000 claims 4
- 150000001413 amino acids Chemical group 0.000 claims 4
- 238000003745 diagnosis Methods 0.000 claims 4
- 239000003550 marker Substances 0.000 claims 4
- 102400001282 Atrial natriuretic peptide Human genes 0.000 claims 3
- 208000020446 Cardiac disease Diseases 0.000 claims 2
- 238000002965 ELISA Methods 0.000 claims 2
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 claims 2
- 208000019622 heart disease Diseases 0.000 claims 2
- 238000010166 immunofluorescence Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000000816 matrix-assisted laser desorption--ionisation Methods 0.000 claims 2
- 208000031225 myocardial ischemia Diseases 0.000 claims 2
- 238000003127 radioimmunoassay Methods 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 208000004476 Acute Coronary Syndrome Diseases 0.000 claims 1
- 206010002388 Angina unstable Diseases 0.000 claims 1
- 102000004625 Aspartate Aminotransferases Human genes 0.000 claims 1
- 108010003415 Aspartate Aminotransferases Proteins 0.000 claims 1
- 101800000407 Brain natriuretic peptide 32 Proteins 0.000 claims 1
- 101800002247 Brain natriuretic peptide 45 Proteins 0.000 claims 1
- 208000031229 Cardiomyopathies Diseases 0.000 claims 1
- 238000000018 DNA microarray Methods 0.000 claims 1
- 108010062715 Fatty Acid Binding Protein 3 Proteins 0.000 claims 1
- 102000011026 Fatty Acid Binding Protein 3 Human genes 0.000 claims 1
- 102000036675 Myoglobin Human genes 0.000 claims 1
- 108010062374 Myoglobin Proteins 0.000 claims 1
- 102000013394 Troponin I Human genes 0.000 claims 1
- 108010065729 Troponin I Proteins 0.000 claims 1
- 102000004987 Troponin T Human genes 0.000 claims 1
- 108090001108 Troponin T Proteins 0.000 claims 1
- 208000007814 Unstable Angina Diseases 0.000 claims 1
- 229940024606 amino acid Drugs 0.000 claims 1
- 230000000890 antigenic effect Effects 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 210000002318 cardia Anatomy 0.000 claims 1
- 229960003624 creatine Drugs 0.000 claims 1
- 239000006046 creatine Substances 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 206010013663 drug dependence Diseases 0.000 claims 1
- 210000003722 extracellular fluid Anatomy 0.000 claims 1
- 210000005003 heart tissue Anatomy 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 201000004332 intermediate coronary syndrome Diseases 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 108010008064 pro-brain natriuretic peptide (1-76) Proteins 0.000 claims 1
- 238000004393 prognosis Methods 0.000 claims 1
- 230000010410 reperfusion Effects 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 208000011117 substance-related disease Diseases 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3062908P | 2008-02-22 | 2008-02-22 | |
| PCT/NZ2009/000022 WO2009104974A2 (en) | 2008-02-22 | 2009-02-20 | Biomarkers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011514156A JP2011514156A (ja) | 2011-05-06 |
| JP2011514156A5 true JP2011514156A5 (enExample) | 2013-05-02 |
Family
ID=40986076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010547586A Pending JP2011514156A (ja) | 2008-02-22 | 2009-02-20 | 急性冠動脈障害のためのバイオマーカー |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20110033874A1 (enExample) |
| EP (1) | EP2263086A4 (enExample) |
| JP (1) | JP2011514156A (enExample) |
| CN (1) | CN102084251A (enExample) |
| AU (1) | AU2009215996A1 (enExample) |
| CA (1) | CA2716280A1 (enExample) |
| WO (1) | WO2009104974A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ605640A (en) * | 2010-07-19 | 2016-01-29 | Otago Innovation Ltd | Signal biomarkers |
| US9696312B2 (en) | 2011-09-02 | 2017-07-04 | The Trustees Of Columbia University In The City Of New York | Diagnosis and treatment of cancer expressing ILT3 or ILT3 ligand |
| CN102628864B (zh) * | 2011-12-30 | 2014-08-13 | 北京九强生物技术股份有限公司 | 胶乳增强免疫比浊法测定血清或尿液中心脏型脂肪酸结合蛋白的试剂盒 |
| CN102636651A (zh) * | 2012-04-06 | 2012-08-15 | 上海领潮生物科技有限公司 | 多项心肌标志物并行检测方法及系统、芯片试纸 |
| US10175250B2 (en) * | 2012-06-11 | 2019-01-08 | Gabriela Venturini Da Silva | Nitrated cardiac troponin I as a biomarker of cardiac ischemia |
| EP3203228B1 (en) * | 2014-09-30 | 2020-08-26 | BGI Shenzhen Co., Limited | Chronic heart disease patient specific biomarker composition and use thereof |
| CN107076710B (zh) * | 2014-09-30 | 2019-10-25 | 深圳华大基因科技有限公司 | 冠心病患者特异性生物标志组合物及其用途 |
| EP3325006A4 (en) | 2015-07-17 | 2019-03-06 | The Trustees of Columbia University in the City of New York | METHOD FOR TREATING CD166-EXPRESSIVE CANCER |
| CN106370753B (zh) * | 2016-10-26 | 2019-02-01 | 王喜军 | 冠心病尿液代谢标记物的鉴定及分析方法 |
| CN111467497B (zh) * | 2020-05-09 | 2022-03-01 | 复旦大学附属中山医院 | Fto作为靶点在治疗压力负荷性心肌损伤中的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005052593A1 (en) * | 2003-10-29 | 2005-06-09 | The University Of Leicester | Detection |
| EP1731910A1 (en) * | 2005-06-07 | 2006-12-13 | F. Hoffmann-La Roche Ag | Use of NT-proANP and NT-proBNP for diagnosing cardiac diseases |
-
2009
- 2009-02-20 AU AU2009215996A patent/AU2009215996A1/en not_active Abandoned
- 2009-02-20 EP EP09713096A patent/EP2263086A4/en not_active Withdrawn
- 2009-02-20 JP JP2010547586A patent/JP2011514156A/ja active Pending
- 2009-02-20 CA CA2716280A patent/CA2716280A1/en not_active Abandoned
- 2009-02-20 WO PCT/NZ2009/000022 patent/WO2009104974A2/en not_active Ceased
- 2009-02-20 US US12/919,002 patent/US20110033874A1/en not_active Abandoned
- 2009-02-20 CN CN2009801135145A patent/CN102084251A/zh active Pending
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