JP2017530090A - インターロイキン２３受容体の経口ペプチド阻害剤および炎症性腸疾患を処置するためのそれらの使用 - Google Patents

インターロイキン２３受容体の経口ペプチド阻害剤および炎症性腸疾患を処置するためのそれらの使用 Download PDF

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JP2017530090A
JP2017530090A JP2017502701A JP2017502701A JP2017530090A JP 2017530090 A JP2017530090 A JP 2017530090A JP 2017502701 A JP2017502701 A JP 2017502701A JP 2017502701 A JP2017502701 A JP 2017502701A JP 2017530090 A JP2017530090 A JP 2017530090A
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JP2017530090A5 (enExample
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グレゴリー ボーン，
グレゴリー ボーン，
アショク バンダーリー，
アショク バンダーリー，
シャオリ チェン，
シャオリ チェン，
ブライアン トロイ フレデリック，
ブライアン トロイ フレデリック，
ジエ ザン，
ジエ ザン，
ディネシュ ブイ． パテル，
ディネシュ ブイ． パテル，
デイビッド リウ，
デイビッド リウ，
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プロタゴニスト セラピューティクス， インコーポレイテッド
プロタゴニスト セラピューティクス， インコーポレイテッド
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates

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  • Otolaryngology (AREA)
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JP2017502701A 2014-07-17 2015-07-15 インターロイキン２３受容体の経口ペプチド阻害剤および炎症性腸疾患を処置するためのそれらの使用 Withdrawn JP2017530090A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462025899P 2014-07-17 2014-07-17
US62/025,899 2014-07-17
US201562119685P 2015-02-23 2015-02-23
US201562119688P 2015-02-23 2015-02-23
US62/119,685 2015-02-23
US62/119,688 2015-02-23
PCT/US2015/040658 WO2016011208A1 (en) 2014-07-17 2015-07-15 Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases

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JP2020099144A Active JP6995933B2 (ja) 2014-07-17 2020-06-08 インターロイキン２３受容体の経口ペプチド阻害剤および炎症性腸疾患を処置するためのそれらの使用

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KR (1) KR102482790B1 (enExample)
CN (2) CN113563423A (enExample)
AU (1) AU2015289642B2 (enExample)
BR (1) BR112017001010A2 (enExample)
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Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018522008A (ja) * 2015-07-15 2018-08-09 プロタゴニスト セラピューティクス， インコーポレイテッド インターロイキン２３受容体のペプチド阻害剤、および炎症性疾患を処置するためのそれらの使用
JP2021530477A (ja) * 2018-07-12 2021-11-11 プロタゴニスト セラピューティクス， インコーポレイテッド インターロイキン−２３受容体のペプチド阻害剤および炎症性疾患を治療するためのその使用
JP2022540154A (ja) * 2019-07-10 2022-09-14 プロタゴニスト セラピューティクス， インコーポレイテッド インターロイキン－２３受容体のペプチド阻害剤及び炎症性疾患を治療するためのその使用
US11472842B2 (en) 2015-12-30 2022-10-18 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
JP2023511552A (ja) * 2020-01-15 2023-03-20 ヤンセン バイオテツク，インコーポレーテツド インターロイキン２３受容体のペプチド阻害剤および炎症性疾患を治療するためのその使用
JP2023520048A (ja) * 2020-03-31 2023-05-15 ケモセントリックス， インコーポレイテッド Ｃｃｒ９阻害剤及び抗ｉｌ－２３遮断抗体を使用する炎症性腸疾患を治療するための組成物及び方法
JP2023531771A (ja) * 2020-06-29 2023-07-25 ユニヴァーシティ オブ ワシントン ヒトｉｌ２３受容体結合ポリペプチド
US11753443B2 (en) 2018-02-08 2023-09-12 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics
JP2023145581A (ja) * 2020-11-20 2023-10-11 ヤンセン ファーマシューティカ エヌ．ベー． インターロイキン－２３受容体のペプチド阻害剤の組成物
JP2023545212A (ja) * 2020-11-20 2023-10-26 ヤンセン ファーマシューティカ エヌ．ベー． インターロイキン－２３受容体のペプチド阻害剤の組成物
US11807674B2 (en) 2013-03-15 2023-11-07 Protagonist Therapeutics, Inc. Hepcidin analogues and uses thereof
US11840581B2 (en) 2014-05-16 2023-12-12 Protagonist Therapeutics, Inc. α4β7 thioether peptide dimer antagonists
US11884748B2 (en) 2014-07-17 2024-01-30 Protagonist Therapeutics, Inc. Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases
US12018057B2 (en) 2020-01-15 2024-06-25 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
US12478617B2 (en) 2021-07-14 2025-11-25 Janssen Biotech, Inc. Lipidated peptide inhibitors of interleukin-23 receptor
JP7787823B2 (ja) 2020-03-31 2025-12-17 ケモセントリックス， インコーポレイテッド Ｃｃｒ９阻害剤及び抗ｉｌ－２３遮断抗体を使用する炎症性腸疾患を治療するための組成物及び方法

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USRE49026E1 (en) 2011-06-14 2022-04-12 Medical Diagnostic Laboratories, Llc Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof
US10301371B2 (en) 2014-10-01 2019-05-28 Protagonist Therapeutics, Inc. Cyclic monomer and dimer peptides having integrin antagonist activity
SG11201702553RA (en) 2014-10-01 2017-04-27 Protagonist Therapeutics Inc NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS
US10787490B2 (en) 2015-07-15 2020-09-29 Protaganist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
US10407468B2 (en) 2016-03-23 2019-09-10 Protagonist Therapeutics, Inc. Methods for synthesizing α4β7 peptide antagonists
WO2018022937A1 (en) * 2016-07-27 2018-02-01 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 and their use to treat inflammatory diseases
WO2018136646A1 (en) 2017-01-18 2018-07-26 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
EP4092038A1 (en) 2017-09-11 2022-11-23 Protagonist Therapeutics, Inc. Opioid agonist peptides and uses thereof
WO2019207427A2 (en) * 2018-04-25 2019-10-31 Janssen Pharmaceutica Nv Thioether cyclic peptide amylin receptor modulators
WO2019215701A1 (en) 2018-05-11 2019-11-14 Janssen Biotech, Inc. Methods of treating depression using il-23 antibodies
US12171764B2 (en) 2018-06-20 2024-12-24 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with a JAK or other kinase inhibitor
WO2019246455A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an integrin inhibitor
WO2019246313A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a tnf inhibitor
EP3810268A1 (en) 2018-06-20 2021-04-28 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor
US20230041197A1 (en) 2018-06-20 2023-02-09 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
CN111040020B (zh) * 2018-12-28 2022-04-12 中国人民解放军军事科学院军事医学研究院 一种烯烃硫醚类订书肽及其制备方法与应用
CN110015978B (zh) * 2019-04-29 2021-03-19 康化（上海）新药研发有限公司 O-[2-[[叔丁氧羰基]氨基]乙基]-n-[芴甲氧羰基]-l-酪氨酸的合成方法
TW202116793A (zh) * 2019-07-10 2021-05-01 美商領導醫療有限公司 介白素-23受體之肽抑制劑及其於治療發炎疾病的用途
CN110790763A (zh) * 2019-11-24 2020-02-14 烟台大学 吡啶并二嘧啶及吡啶并二吡唑衍生物的制备方法
WO2021146458A1 (en) * 2020-01-15 2021-07-22 Protagonist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
AU2022249097A1 (en) * 2021-04-01 2023-10-12 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics
MX2024000761A (es) * 2021-07-14 2024-04-18 Janssen Biotech Inc Inhibidores peptidicos biciclicos del receptor de interleucina-23.
EP4370531A4 (en) * 2021-07-14 2025-09-03 Janssen Biotech Inc PEPTIDE INHIBITORS OF THE INTERLEUKIN-23 RECEPTOR
CA3240982A1 (en) 2021-12-01 2023-06-08 Zealand Pharma A/S Peptide inhibitors of interleukin-23 receptor
KR20230112549A (ko) 2022-01-20 2023-07-27 한국과학기술연구원 로세부리아 속 또는 비피도박테리움 속 유래 세포외소포체를 포함하는, 염증성 질환의 예방, 개선, 또는 치료용 조성물
TW202400659A (zh) * 2022-05-04 2024-01-01 美商詹努克斯治療有限公司 經腫瘤活化之靶向ｃｄ２８及ｐｄ－ｌ１之多特異性抗體及其使用方法
JP2025521647A (ja) 2022-06-30 2025-07-10 サノフイ 選択的ｉｌ－２３受容体アンタゴニストとしての新規ペプチド
KR20250111134A (ko) * 2022-11-30 2025-07-22 상하이 한서 바이오메디컬 컴퍼니 리미티드 폴리펩티드 억제제, 이의 제조 방법 및 응용
WO2024227437A1 (zh) * 2023-05-04 2024-11-07 西藏海思科制药有限公司 白介素-23受体的肽抑制剂制备及其用途
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