|
EP2850093B1
(en)
|
2012-01-27 |
2019-01-09 |
The Board of Trustees of the Leland Stanford Junior University |
Therapeutic il-13 polypeptides
|
|
IN2015KN00329A
(https=)
|
2012-08-09 |
2015-07-10 |
Univ Leland Stanford Junior |
|
|
EP2948544A4
(en)
|
2013-01-28 |
2016-08-03 |
St Jude Childrens Res Hospital |
CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES
|
|
WO2015042705A1
(en)
|
2013-09-24 |
2015-04-02 |
Medicenna Biopharma Inc. |
Interleukin-4 receptor-binding fusion proteins and uses thereof
|
|
EP3057986B1
(en)
*
|
2013-10-17 |
2017-12-27 |
National University of Singapore |
Chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors
|
|
US10144770B2
(en)
|
2013-10-17 |
2018-12-04 |
National University Of Singapore |
Chimeric receptors and uses thereof in immune therapy
|
|
AU2015259877B2
(en)
|
2014-05-15 |
2021-02-25 |
National University Of Singapore |
Modified natural killer cells and uses thereof
|
|
US20170151281A1
(en)
|
2015-02-19 |
2017-06-01 |
Batu Biologics, Inc. |
Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
|
|
CN107995913B
(zh)
|
2015-05-18 |
2022-02-11 |
T细胞受体治疗公司 |
使用融合蛋白对tcr重编程的组合物和方法
|
|
EP3430036A4
(en)
*
|
2016-03-18 |
2019-08-14 |
Unum Therapeutics |
MODIFIED CHIMERIC RECEPTORS AND USES IN IMMUNOTHERAPY
|
|
WO2017205254A1
(en)
*
|
2016-05-23 |
2017-11-30 |
Unum Therapeutics |
Immune cells expressing antibody-coupled t-cell receptor (actr) for use in inhibiting cancer cells expressing surface immunoglobulin
|
|
WO2018017649A1
(en)
*
|
2016-07-19 |
2018-01-25 |
Unum Therapeutics Inc. |
Use of antibody-coupled t cell receptor (actr) with multiple anti-cancer antibodies in cancer treatment
|
|
EP3494138A1
(en)
|
2016-08-02 |
2019-06-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
CA3036745A1
(en)
|
2016-10-07 |
2018-04-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for t-cell receptors reprogramming using fusion proteins
|
|
US11851491B2
(en)
|
2016-11-22 |
2023-12-26 |
TCR2 Therapeutics Inc. |
Compositions and methods for TCR reprogramming using fusion proteins
|
|
CN110352068A
(zh)
|
2016-12-02 |
2019-10-18 |
南加利福尼亚大学 |
合成的免疫受体及其使用方法
|
|
WO2018112266A1
(en)
*
|
2016-12-14 |
2018-06-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Il-13 superkine: immune cell targeting constructs and methods of use thereof
|
|
WO2018132506A1
(en)
|
2017-01-10 |
2018-07-19 |
The General Hospital Corporation |
Chimeric antigen receptors based on alternative signal 1 domains
|
|
EP3573660A4
(en)
*
|
2017-01-30 |
2021-01-06 |
Unum Therapeutics Inc. |
IMPROVED ANTIBODY T-LYMPHOCYTE RECEPTOR CONSTRUCTIONS AND THEIR THERAPEUTIC USES
|
|
US20190381171A1
(en)
*
|
2017-02-17 |
2019-12-19 |
Unum Therapeutics Inc. |
Co-use of anti-bcma antibody and antibody-coupled t cell receptor (actr) in cancer therapy and b cell disorders
|
|
AU2018236450A1
(en)
|
2017-03-16 |
2019-10-03 |
The General Hospital Corporation |
Chimeric antigen receptors targeting CD37
|
|
ES3010117T3
(en)
*
|
2017-03-27 |
2025-04-01 |
Hoffmann La Roche |
Improved antigen binding receptors
|
|
MX2019011570A
(es)
|
2017-03-27 |
2019-11-18 |
Nat Univ Singapore |
Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
|
|
KR102660336B1
(ko)
|
2017-03-27 |
2024-04-26 |
내셔널 유니버시티 오브 싱가포르 |
절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도
|
|
TW201900672A
(zh)
*
|
2017-03-27 |
2019-01-01 |
瑞士商赫孚孟拉羅股份公司 |
改良之抗原結合受體型式
|
|
JP7245177B2
(ja)
|
2017-06-07 |
2023-03-23 |
シージェン インコーポレイテッド |
低減した表面フコシル化を有するｔ細胞、及びそれを作製及び使用する方法
|
|
AU2018327229A1
(en)
*
|
2017-09-06 |
2020-02-27 |
Fred Hutchinson Cancer Center |
Strep-tag specific binding proteins and uses thereof
|
|
WO2019073299A1
(en)
|
2017-10-10 |
2019-04-18 |
Medicenna Therapeutics, Inc. |
IL-4 FUSION FORMULATIONS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM (CNS) TUMORS
|
|
EP3700542A4
(en)
*
|
2017-10-26 |
2020-12-09 |
Regents of the University of Minnesota |
RECOMBINANT IMMUNE CELLS, METHODS OF MANUFACTURING AND METHODS OF USE
|
|
JP7261232B2
(ja)
*
|
2017-11-01 |
2023-04-19 |
アロジーン セラピューティクス，インコーポレイテッド |
改変カスパーゼ－９ポリペプチドおよびその使用方法
|
|
EP3706766A4
(en)
*
|
2017-11-09 |
2021-08-18 |
Sangamo Therapeutics, Inc. |
GENETIC MODIFICATION OF THE CYTOCINE INDUCTIBLE SH2-CONTAINING PROTEIN (CISH) GENE
|
|
CN111683962B
(zh)
|
2017-11-10 |
2025-05-16 |
美国政府(由卫生和人类服务部的部长所代表) |
靶向肿瘤抗原的嵌合抗原受体
|
|
EP3707247A4
(en)
*
|
2017-11-10 |
2021-11-03 |
Jura Bio, Inc. |
MAJOR HISTOCOMPATIBILITY COMPLEX CHEMERICAL RECEPTORS AND ASSOCIATED USES FOR THE TREATMENT OF AUTOIMMUNE DISEASES
|
|
MX2020006435A
(es)
|
2017-12-19 |
2021-02-09 |
Akouos Inc |
Administracion de anticuerpos terapeuticos mediada por vector de virus adenoasociado (aav) en el oido interno.
|
|
CN109970864A
(zh)
*
|
2017-12-28 |
2019-07-05 |
上海细胞治疗研究院 |
一种双向激活共刺激分子受体及其用途
|
|
JP2021508468A
(ja)
*
|
2017-12-29 |
2021-03-11 |
シティ・オブ・ホープＣｉｔｙ ｏｆ Ｈｏｐｅ |
メディトープ対応ｔ細胞
|
|
AU2019219454A1
(en)
|
2018-02-09 |
2020-08-27 |
National University Of Singapore |
Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
|
|
KR102593359B1
(ko)
*
|
2018-03-19 |
2023-10-24 |
사바 라이프 사이언스 에이비 |
Adcc 및 adcp 활성의 향상된 정량화를 위한 시스템 및 제품
|
|
CN112055717B
(zh)
|
2018-04-02 |
2024-04-26 |
新加坡国立大学 |
用在免疫细胞中表达的膜结合抗细胞因子非信号传导粘合剂中和人细胞因子
|
|
IL321548A
(en)
|
2018-05-22 |
2025-08-01 |
Immunitybio Inc |
Recombinant NK cells expressing a chimeric antigen receptor (CAR) for epsilon-FC and uses thereof
|
|
WO2019232523A1
(en)
|
2018-06-01 |
2019-12-05 |
The Board Of Trustees Of The Leland Stanford Junior University |
Il-13/il-4 superkines: immune cell targeting constructs and methods of use thereof
|
|
CA3104862A1
(en)
|
2018-07-03 |
2020-01-09 |
Sotio, LLC |
Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof
|
|
KR20210045418A
(ko)
|
2018-08-14 |
2021-04-26 |
소티오, 엘엘씨 |
크렙스 사이클을 조정하는 트랜스 대사 분자와 조합된 키메라 항원 수용체 폴리펩타이드 및 이의 치료적 용도
|
|
EP3844186A4
(en)
|
2018-08-29 |
2022-08-17 |
National University of Singapore |
METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
|
|
US20240165232A1
(en)
*
|
2018-09-24 |
2024-05-23 |
Fred Hutchinson Cancer Research Center |
Chimeric receptor proteins and uses thereof
|
|
EP3876977A1
(en)
|
2018-11-06 |
2021-09-15 |
The Regents Of The University Of California |
Chimeric antigen receptors for phagocytosis
|
|
US12590148B2
(en)
|
2018-11-26 |
2026-03-31 |
Nkarta, Inc. |
Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
|
|
AU2020232691B2
(en)
|
2019-03-05 |
2023-06-29 |
Nkarta, Inc. |
CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
|
CA3133037A1
(en)
*
|
2019-03-19 |
2020-09-24 |
Ramot At Tel-Aviv University Ltd. |
T cell expressing an fc gamma receptor and methods of use thereof
|
|
AU2020257748A1
(en)
|
2019-04-19 |
2021-11-18 |
Chugai Seiyaku Kabushiki Kaisha |
Chimeric receptor recognizing modification site of antibody
|
|
US11013764B2
(en)
|
2019-04-30 |
2021-05-25 |
Myeloid Therapeutics, Inc. |
Engineered phagocytic receptor compositions and methods of use thereof
|
|
CN110592014A
(zh)
*
|
2019-08-14 |
2019-12-20 |
广东美赛尔细胞生物科技有限公司 |
一种在nk细胞治疗中免辐照体外体内持续去除饲养细胞的方法
|
|
JP7831937B2
(ja)
|
2019-09-03 |
2026-03-17 |
クリエイト・メディシンズ，インコーポレーテッド |
ゲノム組込みのための方法および組成物
|
|
CN111944062B
(zh)
*
|
2019-12-09 |
2023-11-07 |
深圳市体内生物医药科技有限公司 |
一种识别Fc片段的嵌合抗原受体及其应用
|
|
US10980836B1
(en)
|
2019-12-11 |
2021-04-20 |
Myeloid Therapeutics, Inc. |
Therapeutic cell compositions and methods of manufacturing and use thereof
|
|
CN111100942B
(zh)
*
|
2019-12-31 |
2023-03-28 |
海南波莲水稻基因科技有限公司 |
与水稻光温敏核雄性不育表型相关的分子标记和应用
|
|
EP4105240A4
(en)
*
|
2020-02-13 |
2024-05-29 |
Sichuan University |
Chimeric antigen receptor and use thereof
|
|
EP3875478A1
(en)
*
|
2020-03-05 |
2021-09-08 |
Canvax Biotech, S.L. |
Novel non-immunogenic chimeric antigen receptors and uses thereof
|
|
WO2021260696A1
(en)
|
2020-06-22 |
2021-12-30 |
Ramot At Tel-Aviv University Ltd. |
Multi subunit protein modules, cells expressing same and uses thereof
|
|
CN113583139A
(zh)
*
|
2020-07-06 |
2021-11-02 |
上海鑫湾生物科技有限公司 |
一种嵌合受体及其应用
|
|
CN116194124A
(zh)
|
2020-07-31 |
2023-05-30 |
中外制药株式会社 |
包含表达嵌合受体的细胞的药物组合物
|
|
CN111876382A
(zh)
*
|
2020-08-14 |
2020-11-03 |
上海星华生物医药科技有限公司 |
一种制备通用型免疫细胞的方法及其应用
|
|
EP4198120A4
(en)
*
|
2020-08-14 |
2024-05-08 |
Shanghai Xinghua Bio Pharmaceutical Science & Technology Co., Ltd |
METHOD FOR PREPARING UNIVERSAL IMMUNE CELLS AND THEIR USE
|
|
CA3197423A1
(en)
|
2020-11-04 |
2022-05-12 |
Daniel Getts |
Engineered chimeric fusion protein compositions and methods of use thereof
|
|
IL303317A
(en)
|
2020-12-01 |
2023-07-01 |
Akouos Inc |
ANTI-NATURAL ANTIBODY STRUCTURES AND RELATED METHODS FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH VESTIBULAR SWANNOMA
|
|
WO2022140284A1
(en)
*
|
2020-12-22 |
2022-06-30 |
Immunitybio, Inc. |
Fc-receptor car constructs and cells
|
|
US20240317831A1
(en)
*
|
2021-01-08 |
2024-09-26 |
Regents Of The University Of Minnesota |
Nk cell engager molecules and methods of use
|
|
EP4308133A4
(en)
|
2021-03-17 |
2025-01-22 |
Myeloid Therapeutics, Inc. |
MANIPULATED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF
|
|
AU2022272235A1
(en)
|
2021-05-11 |
2023-12-21 |
Create Medicines, Inc. |
Methods and compositions for genomic integration
|
|
WO2023049933A1
(en)
|
2021-09-27 |
2023-03-30 |
Sotio Biotech Inc. |
Chimeric receptor polypeptides in combination with trans metabolism molecules that re-direct glucose metabolites out of the glycolysis pathway and therapeutic uses thereof
|
|
US20250000906A1
(en)
|
2021-11-16 |
2025-01-02 |
Sotio Biotech Inc. |
Treatment of myxoid/round cell liposarcoma patients
|
|
CN120005024A
(zh)
*
|
2022-03-30 |
2025-05-16 |
河北森朗生物科技有限公司 |
抗cd7的纳米抗体及其相关产品和应用
|
|
WO2024040207A1
(en)
|
2022-08-19 |
2024-02-22 |
Sotio Biotech Inc. |
Genetically engineered natural killer (nk) cells with chimeric receptor polypeptides in combination with trans metabolism molecules and therapeutic uses thereof
|
|
US20260053924A1
(en)
|
2022-08-19 |
2026-02-26 |
Sotio Biotech Inc. |
Genetically engineered immune cells with chimeric receptor polypeptides in combination with multiple trans metabolism molecules and therapeutic uses thereof
|
|
WO2024102954A1
(en)
*
|
2022-11-10 |
2024-05-16 |
Massachusetts Institute Of Technology |
Activation induced clipping system (aics)
|
|
EP4694916A1
(en)
|
2023-04-14 |
2026-02-18 |
SOTIO Biotech Inc. |
Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists
|
|
WO2024215987A1
(en)
|
2023-04-14 |
2024-10-17 |
Sotio Biotech Inc. |
IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES
|
|
AU2024269870A1
(en)
*
|
2023-05-05 |
2025-11-20 |
Board Of Regents, The University Of Texas System |
Multi-receptor natural killer cells
|
|
WO2025103439A1
(zh)
*
|
2023-11-16 |
2025-05-22 |
广州瑞风生物科技有限公司 |
一种嵌合抗原受体及其应用
|
|
KR102764613B1
(ko)
*
|
2024-03-28 |
2025-02-12 |
한양대학교 에리카산학협력단 |
NaPi2b 특이적 CAR-T를 포함하는 난소암 치료용 약학 조성물
|
|
WO2025235862A1
(en)
*
|
2024-05-10 |
2025-11-13 |
Inndura Therapeutics Inc. |
A modified immune cell receptor comprising a target-binding domain and the extracellular domain of cd16a
|
|
WO2026077463A1
(zh)
*
|
2024-10-12 |
2026-04-16 |
深圳市济因生物科技有限公司 |
一种嵌合蛋白和工程化免疫细胞及其制备方法与应用
|