JP2017523180A5 - - Google Patents
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- Publication number
- JP2017523180A5 JP2017523180A5 JP2017504354A JP2017504354A JP2017523180A5 JP 2017523180 A5 JP2017523180 A5 JP 2017523180A5 JP 2017504354 A JP2017504354 A JP 2017504354A JP 2017504354 A JP2017504354 A JP 2017504354A JP 2017523180 A5 JP2017523180 A5 JP 2017523180A5
- Authority
- JP
- Japan
- Prior art keywords
- aluminum
- vaccine
- flagellin
- pharmaceutical composition
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462031116P | 2014-07-30 | 2014-07-30 | |
| US62/031,116 | 2014-07-30 | ||
| US201562110744P | 2015-02-02 | 2015-02-02 | |
| US62/110,744 | 2015-02-02 | ||
| US201562117366P | 2015-02-17 | 2015-02-17 | |
| US62/117,366 | 2015-02-17 | ||
| PCT/US2015/042887 WO2016019134A1 (en) | 2014-07-30 | 2015-07-30 | Flagellin-based agents and uses including effective vaccination |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017523180A JP2017523180A (ja) | 2017-08-17 |
| JP2017523180A5 true JP2017523180A5 (enExample) | 2018-09-06 |
| JP6646039B2 JP6646039B2 (ja) | 2020-02-14 |
Family
ID=55218277
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017504404A Expired - Fee Related JP6940916B2 (ja) | 2014-07-30 | 2015-07-29 | フラジェリン組成物および使用 |
| JP2017504354A Expired - Fee Related JP6646039B2 (ja) | 2014-07-30 | 2015-07-30 | フラジェリンベースの薬剤および効果的なワクチン接種を含めた使用 |
| JP2021142801A Pending JP2021191781A (ja) | 2014-07-30 | 2021-09-01 | フラジェリン組成物および使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017504404A Expired - Fee Related JP6940916B2 (ja) | 2014-07-30 | 2015-07-29 | フラジェリン組成物および使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021142801A Pending JP2021191781A (ja) | 2014-07-30 | 2021-09-01 | フラジェリン組成物および使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (9) | US10202426B2 (enExample) |
| EP (2) | EP3174893B1 (enExample) |
| JP (3) | JP6940916B2 (enExample) |
| KR (1) | KR20170031251A (enExample) |
| CN (2) | CN107087411B (enExample) |
| AU (2) | AU2015296555B2 (enExample) |
| BR (1) | BR112017001796A2 (enExample) |
| CA (2) | CA2994218A1 (enExample) |
| EA (2) | EA035372B1 (enExample) |
| ES (1) | ES2816630T3 (enExample) |
| IL (2) | IL250331B (enExample) |
| MX (2) | MX385845B (enExample) |
| WO (2) | WO2016019034A1 (enExample) |
| ZA (1) | ZA201701286B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6940916B2 (ja) * | 2014-07-30 | 2021-09-29 | ゲノム プロテクション,インコーポレイテッド | フラジェリン組成物および使用 |
| WO2016079899A1 (ja) | 2014-11-20 | 2016-05-26 | 国立研究開発法人医薬基盤・健康・栄養研究所 | 異なる核酸アジュバントの組み合わせによる、新規Th1誘導性アジュバントおよびその用途 |
| CA3069733A1 (en) | 2017-07-20 | 2019-01-24 | Spogen Biotech Inc. | Bioactive polypeptides for improvements in plant protection, growth and productivity |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| WO2019094528A1 (en) * | 2017-11-09 | 2019-05-16 | The Scripps Research Institute | An improved heroin vaccine |
| JP7037930B2 (ja) * | 2017-12-19 | 2022-03-17 | 株式会社小糸製作所 | 車両の運転支援装置、命令表示装置及び車両用灯具。 |
| CN109879940A (zh) * | 2017-12-25 | 2019-06-14 | 苏州和锐生物科技有限公司 | 鞭毛g多肽、抗体捕获器件及试剂盒 |
| AU2019261592A1 (en) * | 2018-04-24 | 2020-11-19 | Genome Protection, Inc. | Methods for improving frailty and aging |
| WO2020110154A1 (en) * | 2018-11-30 | 2020-06-04 | Bharat Biotech International Limited | A chimeric therapeutic vaccine |
| CA3122067A1 (en) * | 2018-12-07 | 2020-06-11 | Genome Protection, Inc. | Engineered flagellin-derived compositions and uses |
| CN111718417B (zh) * | 2019-03-19 | 2022-10-14 | 宁波鲲鹏生物科技有限公司 | 含有荧光蛋白片段的融合蛋白及其用途 |
| KR102169663B1 (ko) * | 2019-03-28 | 2020-10-26 | 가톨릭대학교 산학협력단 | 플라젤린으로부터 유도된 tlr5 작용제를 유효성분으로 포함하는 이식편대숙주질환의 예방 또는 치료용 조성물 |
| US12377112B2 (en) | 2019-04-17 | 2025-08-05 | Compass Pathfinder Limited | Methods of treating neurocognitive disorders, chronic pain and reducing inflammation |
| CN110157655B (zh) * | 2019-05-22 | 2021-06-01 | 中国兽医药品监察所 | 一种无毒性气肿疽梭菌基因工程亚单位疫苗用菌种及其应用 |
| US20220288198A1 (en) * | 2019-08-30 | 2022-09-15 | Genome Protection, Inc. | Methods of increasing vaccine efficacy |
| JP7766623B2 (ja) | 2020-05-19 | 2025-11-10 | サイビン アイアールエル リミテッド | 重水素化トリプタミン誘導体および使用方法 |
| US20220389065A1 (en) * | 2020-06-04 | 2022-12-08 | The Catholic University Of Korea Industry-Academic Cooperation Foundation | Anticancer composition comprising tlr5 agonist derived from flagellin as active ingredient |
| TWI746188B (zh) * | 2020-09-28 | 2021-11-11 | 中山醫學大學 | 篩選治療腦炎藥物之平台及其方法 |
| CA3208643A1 (en) | 2021-01-18 | 2022-07-21 | Conserv Bioscience Limited | Coronavirus immunogenic compositions, methods and uses thereof |
| CN118871092A (zh) * | 2021-06-30 | 2024-10-29 | Inserm(法国国家健康医学研究院) | 用于肺部递送鞭毛蛋白的气雾剂组合物 |
| KR102483177B1 (ko) * | 2021-07-09 | 2022-12-29 | 전남대학교산학협력단 | 탈-면역 플라젤린 및 이를 포함하는 백신 조성물 |
| KR102514849B1 (ko) * | 2021-10-28 | 2023-03-28 | 전남대학교산학협력단 | 수지상 세포를 표적하는 신규한 펩타이드, 및 이를 포함하는 암 치료용 조성물 |
| AU2023281711A1 (en) * | 2022-06-01 | 2024-11-28 | Flag Bio, Inc. | Rna adjuvants, methods and uses thereof |
| WO2024035137A1 (ko) * | 2022-08-10 | 2024-02-15 | 주식회사 메디스팬 | 바실러스 서브틸리스 플라젤린 변이체 및 이의 용도 |
| WO2025172452A1 (en) * | 2024-02-14 | 2025-08-21 | Institut National de la Santé et de la Recherche Médicale | Combination for treating bacterial infection due to pseudomonas aeruginosa antibiotic-resistant strain |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3007812A (en) | 1957-02-11 | 1961-11-07 | Allied Chem | Water-repellent compositions, method of water-proofing porous surfaces therewith, and resulting water-repellent surfaces |
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US5399494A (en) | 1983-03-04 | 1995-03-21 | The University Of Maryland System | Vibrio cholerae strain CVD103Hgr, method of making same, and vaccines derived therefrom |
| US6130082A (en) | 1988-05-05 | 2000-10-10 | American Cyanamid Company | Recombinant flagellin vaccines |
| WO1990006696A2 (en) * | 1988-12-19 | 1990-06-28 | Praxis Biologics, Inc. | Meningococcal class 1 outer-membrane protein vaccine |
| JPH05502402A (ja) | 1990-09-28 | 1993-04-28 | ゲブリユーダー ズルツアー アクチエンゲゼルシヤフト | 医療用の中空針及びその製造方法 |
| AU3630093A (en) | 1992-03-02 | 1993-10-05 | Biocine S.P.A. | Helicobacter pylori proteins useful for vaccines and diagnostics |
| US5693476A (en) | 1995-02-24 | 1997-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of screening for compounds capable of modulating vesicular release |
| US20020009747A1 (en) | 1997-08-25 | 2002-01-24 | Freda Diane Miller | Methods and reagents for identifying modulators of neuronal apoptosis |
| US5994409A (en) | 1997-12-09 | 1999-11-30 | U.S. Bioscience, Inc. | Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds |
| US6586008B1 (en) * | 1999-08-25 | 2003-07-01 | Advanced Inhalation Research, Inc. | Use of simple amino acids to form porous particles during spray drying |
| WO2001040280A2 (en) | 1999-11-29 | 2001-06-07 | Inotek Corporation | Composition and method for treating a microbial infection |
| ATE360643T1 (de) | 2000-01-31 | 2007-05-15 | Munin Corp | Humanes cyr61 |
| US7300749B2 (en) | 2000-02-17 | 2007-11-27 | Millennium Pharmaceuticals, Inc. | Molecules of the pyrin domain protein family and uses thereof |
| WO2002044363A1 (en) | 2000-11-28 | 2002-06-06 | Genesis Research And Development Corporation Limited | Methods for modulating apoptotic cell death |
| US8703146B2 (en) | 2001-04-20 | 2014-04-22 | Institute For Systems Biology | Toll-like receptor 5 ligands and methods of use |
| EP1379552B2 (en) | 2001-04-20 | 2014-11-19 | The Institute for Systems Biology | Toll-like receptor 5 ligands and methods of use |
| WO2003028659A2 (en) | 2001-10-02 | 2003-04-10 | University Of Chicago | Methods and compositions for modulating apoptosis |
| US7078165B2 (en) | 2003-03-27 | 2006-07-18 | Institut Pasteur | Method for modulating Nod1 activity, use of a MTP related molecule for modulating Nod1 activity, and therapeutic applications thereof |
| US7638485B2 (en) | 2003-12-02 | 2009-12-29 | Cleveland Biolabs, Inc. | Modulating apoptosis |
| WO2005056041A2 (en) | 2003-12-02 | 2005-06-23 | Cleveland Clinic Foundation | METHODS OF INHIBITING APOPTOSIS USING LATENT TGFβ |
| WO2005056054A2 (en) | 2003-12-02 | 2005-06-23 | Cleveland Clinic Foundation | METHODS OF INHIBITING APOPTOSIS USING INDUCERS OF NF-κB |
| PT1706133E (pt) * | 2003-12-02 | 2010-12-07 | Cleveland Clinic Foundation | Métodos para protecção contra radiação utilizando flagelina |
| US20050266391A1 (en) | 2004-01-15 | 2005-12-01 | Bennett Brydon L | Methods for preserving tissue |
| US7404963B2 (en) | 2004-10-01 | 2008-07-29 | The University Of South Florida | Flagellin-based adjuvants and vaccines |
| US7794731B2 (en) | 2004-12-16 | 2010-09-14 | Wake Forest University Health Sciences | Use of flagellin in the immunotherapy of Yersinia pestis |
| WO2006069198A1 (en) | 2004-12-22 | 2006-06-29 | Cleveland Clinic Foundation | Flagellin related polypeptides and uses thereof |
| EP1940419A2 (en) | 2005-09-09 | 2008-07-09 | Oregon Health and Science University | Neuroprotectants |
| WO2007070623A2 (en) | 2005-12-14 | 2007-06-21 | Medistem Laboratories, Inc. | Transcatheter tumor immunoembolization |
| EP1979488A4 (en) | 2006-01-09 | 2009-05-27 | Univ California | IMMUNOSTIMULATING COMBINATIONS OF TNFRSF, TLR, NLR, RHR, PURINERIC RECEPTOR, AND CYTOKIN RECEPTOR ANTONISTS FOR VACCINES AND TUMOR IMMUNOTHERAPY |
| WO2008094275A1 (en) | 2007-01-30 | 2008-08-07 | New York University | Peptides for treatment of conditions associated with nitric oxide |
| CN101778861A (zh) | 2007-06-15 | 2010-07-14 | Immurx公司 | Tlr激动剂和/或1型干扰素减轻tnf-r激动剂治疗方案的毒性的用途 |
| WO2009018500A1 (en) | 2007-07-31 | 2009-02-05 | The Johns Hopkins University | Polypeptide-nucleic acid conjugate for immunoprophylaxis or immunotherapy for neoplastic or infectious disorders |
| EP2224954B1 (en) | 2007-11-07 | 2014-01-08 | Celldex Therapeutics, Inc. | Antibodies that bind human dendritic and epithelial cell 205 (dec-205) |
| WO2009102818A1 (en) | 2008-02-11 | 2009-08-20 | Cleveland Biolabs, Inc. | Method for reducing the effects of chemotheraphy using flagellin related polypeptides |
| PT2320948E (pt) | 2008-08-01 | 2013-06-17 | Cleveland Clinic Foundation | Métodos para o tratamento de lesões por reperfusão |
| WO2010040096A2 (en) | 2008-10-03 | 2010-04-08 | Emory University | Methods for the treatment of graft-versus-host disease |
| JP5913093B2 (ja) | 2009-05-21 | 2016-04-27 | アストラゼネカ アクチボラグ | 新規ピリミジン誘導体と、癌とさらなる疾患の治療におけるそれらの使用 |
| SG178954A1 (en) | 2009-09-02 | 2012-04-27 | Novartis Ag | Immunogenic compositions including tlr activity modulators |
| AP2012006253A0 (en) | 2009-10-06 | 2012-06-30 | Panacela Labs Inc | Use of toll-like receptors and agonist for treating cancer. |
| US9682133B2 (en) * | 2010-03-17 | 2017-06-20 | Cornell University | Disrupted adenovirus-based vaccine against drugs of abuse |
| CN103945863A (zh) * | 2011-08-01 | 2014-07-23 | 爱默蕾大学 | 包含配体的vlp及其相关方法 |
| CN102965386A (zh) * | 2011-09-02 | 2013-03-13 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 一种重组细菌鞭毛蛋白衍生多肽的制备和活性鉴定方法 |
| CN102772795B (zh) * | 2012-08-06 | 2015-07-29 | 中国人民解放军疾病预防控制所 | 布鲁氏菌鞭毛蛋白bmeii1112在制备布鲁氏菌亚单位疫苗中的应用 |
| JP6940916B2 (ja) * | 2014-07-30 | 2021-09-29 | ゲノム プロテクション,インコーポレイテッド | フラジェリン組成物および使用 |
-
2015
- 2015-07-29 JP JP2017504404A patent/JP6940916B2/ja not_active Expired - Fee Related
- 2015-07-29 BR BR112017001796-2A patent/BR112017001796A2/pt not_active Application Discontinuation
- 2015-07-29 US US15/329,870 patent/US10202426B2/en active Active
- 2015-07-29 CA CA2994218A patent/CA2994218A1/en active Pending
- 2015-07-29 KR KR1020177005615A patent/KR20170031251A/ko not_active Ceased
- 2015-07-29 ES ES15827248T patent/ES2816630T3/es active Active
- 2015-07-29 MX MX2017001279A patent/MX385845B/es unknown
- 2015-07-29 EP EP15827248.4A patent/EP3174893B1/en active Active
- 2015-07-29 CN CN201580048628.1A patent/CN107087411B/zh not_active Expired - Fee Related
- 2015-07-29 AU AU2015296555A patent/AU2015296555B2/en not_active Ceased
- 2015-07-29 WO PCT/US2015/042684 patent/WO2016019034A1/en not_active Ceased
- 2015-07-29 EA EA201790273A patent/EA035372B1/ru unknown
- 2015-07-30 AU AU2015296298A patent/AU2015296298B2/en not_active Ceased
- 2015-07-30 JP JP2017504354A patent/JP6646039B2/ja not_active Expired - Fee Related
- 2015-07-30 US US15/500,133 patent/US10336793B2/en active Active
- 2015-07-30 MX MX2017001406A patent/MX2017001406A/es unknown
- 2015-07-30 WO PCT/US2015/042887 patent/WO2016019134A1/en not_active Ceased
- 2015-07-30 CA CA2994289A patent/CA2994289C/en active Active
- 2015-07-30 EP EP15827000.9A patent/EP3174552B1/en active Active
- 2015-07-30 EA EA201790294A patent/EA037407B1/ru unknown
- 2015-07-30 CN CN201580052842.4A patent/CN107073092A/zh active Pending
-
2017
- 2017-01-29 IL IL250331A patent/IL250331B/en active IP Right Grant
- 2017-01-29 IL IL250334A patent/IL250334B/en unknown
- 2017-02-21 ZA ZA2017/01286A patent/ZA201701286B/en unknown
-
2018
- 2018-06-25 US US16/017,251 patent/US20180354995A1/en not_active Abandoned
- 2018-12-20 US US16/226,909 patent/US10669316B2/en not_active Expired - Fee Related
-
2019
- 2019-05-16 US US16/414,403 patent/US10730915B2/en not_active Expired - Fee Related
-
2020
- 2020-02-27 US US16/802,859 patent/US11034733B2/en not_active Expired - Fee Related
- 2020-06-24 US US16/910,347 patent/US10975127B2/en not_active Expired - Fee Related
-
2021
- 2021-03-09 US US17/195,935 patent/US11542306B2/en active Active
- 2021-05-13 US US17/319,250 patent/US20210340190A1/en not_active Abandoned
- 2021-09-01 JP JP2021142801A patent/JP2021191781A/ja active Pending
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