JP2017522871A5 - - Google Patents
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- JP2017522871A5 JP2017522871A5 JP2017501287A JP2017501287A JP2017522871A5 JP 2017522871 A5 JP2017522871 A5 JP 2017522871A5 JP 2017501287 A JP2017501287 A JP 2017501287A JP 2017501287 A JP2017501287 A JP 2017501287A JP 2017522871 A5 JP2017522871 A5 JP 2017522871A5
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- 101100112922 Candida albicans CDR3 gene Proteins 0.000 claims description 200
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- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 10
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- HXCHCVDVKSCDHU-LULTVBGHSA-N calicheamicin Chemical compound C1[C@H](OC)[C@@H](NCC)CO[C@H]1O[C@H]1[C@H](O[C@@H]2C\3=C(NC(=O)OC)C(=O)C[C@](C/3=C/CSSSC)(O)C#C\C=C/C#C2)O[C@H](C)[C@@H](NO[C@@H]2O[C@H](C)[C@@H](SC(=O)C=3C(=C(OC)C(O[C@H]4[C@@H]([C@H](OC)[C@@H](O)[C@H](C)O4)O)=C(I)C=3C)OC)[C@@H](O)C2)[C@@H]1O HXCHCVDVKSCDHU-LULTVBGHSA-N 0.000 claims description 2
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201400380 | 2014-07-11 | ||
| DKPA201400380 | 2014-07-11 | ||
| DKPA201400489 | 2014-09-01 | ||
| DKPA201400489 | 2014-09-01 | ||
| DKPA201400746 | 2014-12-22 | ||
| DKPA201400746 | 2014-12-22 | ||
| DKPA201500283 | 2015-05-12 | ||
| DKPA201500283 | 2015-05-12 | ||
| PCT/EP2015/065900 WO2016005593A1 (en) | 2014-07-11 | 2015-07-10 | Antibodies binding axl |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020080943A Division JP2020141682A (ja) | 2014-07-11 | 2020-05-01 | Ａｘｌに結合する抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017522871A JP2017522871A (ja) | 2017-08-17 |
| JP2017522871A5 true JP2017522871A5 (enExample) | 2018-08-16 |
| JP6701162B2 JP6701162B2 (ja) | 2020-05-27 |
Family
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017501287A Active JP6701162B2 (ja) | 2014-07-11 | 2015-07-10 | Ａｘｌに結合する抗体 |
| JP2020080943A Pending JP2020141682A (ja) | 2014-07-11 | 2020-05-01 | Ａｘｌに結合する抗体 |
| JP2023198745A Pending JP2024026158A (ja) | 2014-07-11 | 2023-11-24 | Ａｘｌに結合する抗体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020080943A Pending JP2020141682A (ja) | 2014-07-11 | 2020-05-01 | Ａｘｌに結合する抗体 |
| JP2023198745A Pending JP2024026158A (ja) | 2014-07-11 | 2023-11-24 | Ａｘｌに結合する抗体 |
Country Status (27)
| Country | Link |
|---|---|
| US (6) | US10512688B2 (enExample) |
| EP (2) | EP3169706B1 (enExample) |
| JP (3) | JP6701162B2 (enExample) |
| KR (1) | KR102586656B1 (enExample) |
| CN (2) | CN114621347B (enExample) |
| AU (3) | AU2015286569B2 (enExample) |
| CA (1) | CA2952758A1 (enExample) |
| CY (1) | CY1122721T1 (enExample) |
| DK (1) | DK3169706T3 (enExample) |
| EA (1) | EA201790173A1 (enExample) |
| ES (1) | ES2774428T3 (enExample) |
| HR (1) | HRP20200283T1 (enExample) |
| HU (1) | HUE048667T2 (enExample) |
| IL (2) | IL296633A (enExample) |
| LT (1) | LT3169706T (enExample) |
| ME (1) | ME03665B (enExample) |
| MX (1) | MX370807B (enExample) |
| NZ (1) | NZ728019A (enExample) |
| PL (1) | PL3169706T3 (enExample) |
| PT (1) | PT3169706T (enExample) |
| RS (1) | RS60012B1 (enExample) |
| SG (2) | SG11201610777VA (enExample) |
| SI (1) | SI3169706T1 (enExample) |
| SM (1) | SMT202000265T1 (enExample) |
| UA (1) | UA127198C2 (enExample) |
| WO (1) | WO2016005593A1 (enExample) |
| ZA (1) | ZA201608609B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202000265T1 (it) | 2014-07-11 | 2020-07-08 | Genmab As | Anticorpi che legano axl |
| PL3319993T3 (pl) * | 2015-07-10 | 2020-07-27 | Genmab A/S | Specyficzne wobec AXL koniugaty przeciwciało-lek do leczenia raka |
| KR20180101479A (ko) | 2016-01-13 | 2018-09-12 | 젠맵 에이/에스 | 항체 및 그의 약물 접합체를 위한 제제 |
| SMT202600033T1 (it) * | 2016-04-15 | 2026-03-09 | Bioatla Inc | Anticorpi anti-axl, frammenti di anticorpo e loro immunoconiugati e loro utilizzi |
| WO2017200493A1 (en) | 2016-05-20 | 2017-11-23 | Agency For Science, Technology And Research | Anti-axl tyrosine kinase receptor antibodies and uses thereof |
| MX383920B (es) | 2016-05-26 | 2025-03-14 | Recurium Ip Holdings Llc | Compuestos inhibidores de egfr. |
| US20190233522A1 (en) | 2016-07-08 | 2019-08-01 | Genmab A/S | New dosage regimens for antibody drug conjugates based on anti-axl antibodies |
| US11249081B2 (en) | 2016-08-31 | 2022-02-15 | Agency For Science, Technology And Research | Methods for the identification, targeting and isolation of human dendritic cell (DC) precursors “pre-DC” and their uses thereof |
| CN108285487B (zh) * | 2017-01-08 | 2021-02-19 | 浙江昭华生物医药有限公司 | 抗5t4抗体-药物偶联物及其应用 |
| ES2928773T3 (es) | 2017-01-17 | 2022-11-22 | Heparegenix Gmbh | Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos |
| SG11202002331QA (en) | 2017-09-13 | 2020-04-29 | Nat Res Council Canada | Axl-specific antibodies and uses thereof |
| CN107987163B (zh) * | 2017-12-04 | 2018-11-20 | 杭州尚健生物技术有限公司 | 单克隆抗体9a及其应用 |
| CA3095986A1 (en) * | 2018-04-10 | 2019-10-17 | Genmab A/S | Axl-specific antibodies for cancer treatment |
| CN110483639A (zh) * | 2018-05-15 | 2019-11-22 | 复旦大学 | 靶向axl的抗体及抗体-药物偶联物及其制备方法和用途 |
| EP3810649A1 (en) | 2018-06-22 | 2021-04-28 | Genmab A/S | Method for producing a controlled mixture of two or more different antibodies |
| WO2020065396A1 (en) | 2018-09-26 | 2020-04-02 | Genmab A/S | Axl-specific antibodies for treatment of non-small cell lung cancer |
| AU2019372436A1 (en) * | 2018-11-01 | 2021-05-20 | Merck Patent Gmbh | Methods of administering anti-TIM-3 antibodies |
| EP3965894A4 (en) * | 2019-05-07 | 2023-09-13 | Board of Regents, The University of Texas System | METHOD FOR PREDICTING DRUG RESPONSE IN SAMPLES FROM CANCER PATIENTS |
| EP3999542A1 (en) | 2019-07-19 | 2022-05-25 | Genmab A/S | Axl antibody-drug conjugates for use in treating cancer |
| CN118465272B (zh) * | 2019-12-04 | 2025-08-19 | 珠海泰诺麦博制药股份有限公司 | 抗人巨细胞病毒抗体及其用途 |
| JP2023509760A (ja) | 2020-01-08 | 2023-03-09 | シンシス セラピューティクス，インコーポレイテッド | Ａｌｋ５阻害剤複合体およびその使用 |
| JP7669062B2 (ja) * | 2020-08-19 | 2025-04-28 | ファームアブシン・インコーポレイテッド | 変形抗体及びその製造方法 |
| EP4286406A4 (en) | 2021-01-29 | 2025-07-23 | Illimis Therapeutics Inc | FUSION MOLECULE WITH NON-INFLAMMATORY PHAGOCYTOSIS-INDUCING ACTIVITY |
| US20250019446A1 (en) * | 2021-06-16 | 2025-01-16 | Shanghai Sinobay Biotechnology Co., Ltd. | Antibody Targeting Axl Protein and Antigen Binding Fragment Thereof, and Preparation Method Therefor and Application Thereof |
| WO2022269605A1 (en) | 2021-06-24 | 2022-12-29 | Yeda Research And Development Co. Ltd. | Combination therapy for the treatment of cancer comprising an anti-egfr antibody and an axl-inhibitor |
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