JPWO2021142002A5 - - Google Patents

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Publication number
JPWO2021142002A5
JPWO2021142002A5 JP2022535120A JP2022535120A JPWO2021142002A5 JP WO2021142002 A5 JPWO2021142002 A5 JP WO2021142002A5 JP 2022535120 A JP2022535120 A JP 2022535120A JP 2022535120 A JP2022535120 A JP 2022535120A JP WO2021142002 A5 JPWO2021142002 A5 JP WO2021142002A5
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Japan
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seq
amino acid
acid sequence
set forth
sequence set
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JP2022535120A
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Japanese (ja)
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JP2023509323A (ja
JP7606518B2 (ja
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Priority claimed from PCT/US2021/012329 external-priority patent/WO2021142002A1/en
Publication of JP2023509323A publication Critical patent/JP2023509323A/ja
Publication of JPWO2021142002A5 publication Critical patent/JPWO2021142002A5/ja
Priority to JP2024147372A priority Critical patent/JP2024170466A/ja
Application granted granted Critical
Publication of JP7606518B2 publication Critical patent/JP7606518B2/ja
Priority to JP2025154025A priority patent/JP2025178338A/ja
Priority to JP2025154024A priority patent/JP2025178337A/ja
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JP2022535120A 2020-01-06 2021-01-06 抗ccr8抗体及びその使用 Active JP7606518B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2024147372A JP2024170466A (ja) 2020-01-06 2024-08-29 抗ccr8抗体及びその使用
JP2025154025A JP2025178338A (ja) 2020-01-06 2025-09-17 抗ccr8抗体及びその使用
JP2025154024A JP2025178337A (ja) 2020-01-06 2025-09-17 抗ccr8抗体及びその使用

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202062957758P 2020-01-06 2020-01-06
US62/957,758 2020-01-06
US202062985152P 2020-03-04 2020-03-04
US62/985,152 2020-03-04
US202063198803P 2020-11-13 2020-11-13
US63/198,803 2020-11-13
PCT/US2021/012329 WO2021142002A1 (en) 2020-01-06 2021-01-06 Anti-ccr8 antibodies and uses thereof

Related Child Applications (1)

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JP2024147372A Division JP2024170466A (ja) 2020-01-06 2024-08-29 抗ccr8抗体及びその使用

Publications (3)

Publication Number Publication Date
JP2023509323A JP2023509323A (ja) 2023-03-08
JPWO2021142002A5 true JPWO2021142002A5 (enExample) 2024-01-04
JP7606518B2 JP7606518B2 (ja) 2024-12-25

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Application Number Title Priority Date Filing Date
JP2022535120A Active JP7606518B2 (ja) 2020-01-06 2021-01-06 抗ccr8抗体及びその使用
JP2024147372A Pending JP2024170466A (ja) 2020-01-06 2024-08-29 抗ccr8抗体及びその使用
JP2025154024A Pending JP2025178337A (ja) 2020-01-06 2025-09-17 抗ccr8抗体及びその使用
JP2025154025A Pending JP2025178338A (ja) 2020-01-06 2025-09-17 抗ccr8抗体及びその使用

Family Applications After (3)

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JP2024147372A Pending JP2024170466A (ja) 2020-01-06 2024-08-29 抗ccr8抗体及びその使用
JP2025154024A Pending JP2025178337A (ja) 2020-01-06 2025-09-17 抗ccr8抗体及びその使用
JP2025154025A Pending JP2025178338A (ja) 2020-01-06 2025-09-17 抗ccr8抗体及びその使用

Country Status (12)

Country Link
US (1) US11859000B2 (enExample)
EP (1) EP4087607A1 (enExample)
JP (4) JP7606518B2 (enExample)
KR (2) KR20250095745A (enExample)
CN (1) CN114929278A (enExample)
AR (1) AR132614A2 (enExample)
AU (2) AU2021205877B2 (enExample)
CA (1) CA3160204A1 (enExample)
IL (2) IL321341A (enExample)
MX (3) MX2022008341A (enExample)
TW (1) TWI845803B (enExample)
WO (1) WO2021142002A1 (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI845803B (zh) 2020-01-06 2024-06-21 美商法西尼克斯股份有限公司 抗ccr8抗體及其用途
US20230063151A1 (en) * 2020-01-29 2023-03-02 The Wistar Institute Of Anatomy And Biology Cd40-l blockade to enhance synthetic antibody therapy
TW202216771A (zh) * 2020-06-26 2022-05-01 德商拜耳廠股份有限公司 用於治療應用之ccr8抗體
MX2023004349A (es) 2020-10-16 2023-08-22 Lanova Medicines Ltd Anticuerpos monoclonales anti-ccr8 y sus usos.
EP4317439A4 (en) 2021-03-31 2025-04-02 Shionogi & Co., Ltd. Chimeric antigen receptor that recognizes CCR8 as an antigen
CR20230581A (es) * 2021-06-04 2024-02-13 Amgen Inc Anticuerpos anti-CCR8 y usos de los mismos
HUE069018T2 (hu) * 2021-07-27 2025-02-28 Abbvie Inc Anti-CCR8 antitestek
US20250019451A1 (en) * 2021-08-20 2025-01-16 Hifibio, Inc. Anti-ccr8 antibodies and uses thereof
US20250368744A1 (en) * 2021-12-23 2025-12-04 Concept To Medicine Biotech Co., Ltd. Anti-ccr8 antibodies and uses thereof
CN116789820A (zh) * 2022-03-18 2023-09-22 北京天诺健成医药科技有限公司 一种新型免疫调节剂的开发和应用
WO2023206350A1 (en) * 2022-04-29 2023-11-02 Analytical Biosciences Shanghai Limited Anti-ccr8 antibodies and uses thereof
KR20250018387A (ko) 2022-05-24 2025-02-05 브리스톨-마이어스 스큅 컴퍼니 인간 ccr8에 결합하는 항체
CA3258344A1 (en) 2022-06-07 2023-12-14 Actinium Pharmaceuticals Inc CHELETARIANS AND BIFUNCTIONAL CONJUGATES
WO2024008110A1 (zh) * 2022-07-07 2024-01-11 四川思柏沃生物技术有限公司 抗ccr8抗体及其应用
AU2023319869A1 (en) * 2022-08-04 2025-02-20 Beone Medicines I Gmbh Anti-ccr8 antibodies and methods of use
AU2023325323A1 (en) * 2022-08-19 2025-03-27 Fibrogen, Inc. Anti-ccr8 antibodies and uses thereof
WO2024062082A1 (en) 2022-09-21 2024-03-28 Domain Therapeutics Anti-ccr8 monoclonal antibodies and their therapeutic use
WO2024062019A1 (en) 2022-09-21 2024-03-28 Synabs Anti-ccr8 antibodies and uses thereof
WO2024062072A2 (en) 2022-09-21 2024-03-28 Domain Therapeutics Anti-ccr8 monoclonal antibodies and their therapeutic use
WO2024062076A1 (en) 2022-09-21 2024-03-28 Domain Therapeutics Anti-ccr8 monoclonal antibodies and their therapeutic use
KR20250099234A (ko) * 2022-11-04 2025-07-01 바이오세우스 인크. 항-ccr8 항체 및 이의 용도
WO2024109657A1 (zh) * 2022-11-22 2024-05-30 上海宏成药业有限公司 抗ccr8抗体及其用途
TW202423987A (zh) * 2022-12-07 2024-06-16 大陸商廣東菲鵬製藥股份有限公司 抗ccr8抗體及其應用
TW202436351A (zh) 2023-02-06 2024-09-16 德商拜耳廠股份有限公司 Ccr8抗體及dgk抑制劑之組合
WO2024240224A1 (zh) * 2023-05-23 2024-11-28 再鼎医药(上海)有限公司 包含抗ccr8抗体的制剂及其用途
WO2024255753A1 (zh) * 2023-06-12 2024-12-19 南京蓬勃生物科技有限公司 结合人ccr8的抗体及其用途
WO2024255467A1 (en) * 2023-06-16 2024-12-19 Genor Biopharma Co., Ltd. Anti-ccr8 antibody and anti-ccr8/ctla4 bispecific antibody
CN117285627B (zh) * 2023-09-06 2024-06-14 百济神州(上海)生物科技有限公司 抗ccr8抗体及其用途
WO2025061993A1 (en) 2023-09-21 2025-03-27 Domain Therapeutics Anti-ccr8 monoclonal antibodies and their therapeutic use
WO2025061994A1 (en) 2023-09-21 2025-03-27 Domain Therapeutics Anti-ccr8 monoclonal antibodies and their therapeutic use
WO2025076288A1 (en) 2023-10-06 2025-04-10 Amgen Inc. Combination therapy for cancer treatment
WO2025113643A1 (en) 2023-12-01 2025-06-05 Gilead Sciences Inc. Anti-fap-light fusion protein and use thereof
WO2025145207A1 (en) 2023-12-29 2025-07-03 Bristol-Myers Squibb Company Combination therapy of kras inhibitor and treg-depleting agent
WO2025186043A1 (en) 2024-03-06 2025-09-12 Bayer Aktiengesellschaft Pharmaceutical formulation for anti-ccr8 antibodies
WO2025191147A1 (en) 2024-03-14 2025-09-18 Synabs Anti-ccr8 antibodies and uses thereof
WO2025226603A1 (en) 2024-04-22 2025-10-30 Surface Oncology, LLC Methods for treating cancer using anti-ccr8 antibodies
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
DE3374837D1 (en) 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
EP0143949B1 (en) 1983-11-01 1988-10-12 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Pharmaceutical composition containing urokinase
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
AU600575B2 (en) 1987-03-18 1990-08-16 Sb2, Inc. Altered antibodies
EP1997891A1 (en) 1988-09-02 2008-12-03 Dyax Corporation Generation and selection of recombinant varied binding proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5780225A (en) 1990-01-12 1998-07-14 Stratagene Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
WO1991010737A1 (en) 1990-01-11 1991-07-25 Molecular Affinities Corporation Production of antibodies using gene libraries
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5698426A (en) 1990-09-28 1997-12-16 Ixsys, Incorporated Surface expression libraries of heteromeric receptors
WO1992009690A2 (en) 1990-12-03 1992-06-11 Genentech, Inc. Enrichment method for variant proteins with altered binding properties
US6565841B1 (en) 1991-03-15 2003-05-20 Amgen, Inc. Pulmonary administration of granulocyte colony stimulating factor
DE69233750D1 (de) 1991-04-10 2009-01-02 Scripps Research Inst Bibliotheken heterodimerer Rezeptoren mittels Phagemiden
EP0590058B1 (en) 1991-06-14 2003-11-26 Genentech, Inc. HUMANIZED Heregulin ANTIBODy
ATE408012T1 (de) 1991-12-02 2008-09-15 Medical Res Council Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
US5470582A (en) 1992-02-07 1995-11-28 Syntex (U.S.A.) Inc. Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
US5714350A (en) 1992-03-09 1998-02-03 Protein Design Labs, Inc. Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
US5733743A (en) 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
US6005079A (en) 1992-08-21 1999-12-21 Vrije Universiteit Brussels Immunoglobulins devoid of light chains
EP0656946B2 (en) 1992-08-21 2010-03-31 Vrije Universiteit Brussel Immunoglobulins devoid of light chains
DE69427974T2 (de) 1993-04-29 2001-12-06 Unilever N.V., Rotterdam Herstellung von antikörpern oder funktionstüchtig gemachten teilen davon, abgeleitet von schweren ketten von immunglobulinen von camelidae
WO1994029351A2 (en) 1993-06-16 1994-12-22 Celltech Limited Antibodies
WO1995015982A2 (en) 1993-12-08 1995-06-15 Genzyme Corporation Process for generating specific antibodies
DK1231268T3 (da) 1994-01-31 2005-11-21 Univ Boston Polyklonale antistofbiblioteker
US5516637A (en) 1994-06-10 1996-05-14 Dade International Inc. Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
CA2229043C (en) 1995-08-18 2016-06-07 Morphosys Gesellschaft Fur Proteinoptimierung Mbh Protein/(poly)peptide libraries
JP2978435B2 (ja) 1996-01-24 1999-11-15 チッソ株式会社 アクリロキシプロピルシランの製造方法
AU3117697A (en) 1996-05-06 1997-11-26 Uab Research Foundation, The Radiolabeled fusion toxins for cancer therapy
DE69937291T2 (de) 1998-04-02 2008-07-10 Genentech, Inc., South San Francisco Antikörpervarianten und fragmente davon
US6194551B1 (en) 1998-04-02 2001-02-27 Genentech, Inc. Polypeptide variants
US6995259B1 (en) 1998-10-23 2006-02-07 Sirna Therapeutics, Inc. Method for the chemical synthesis of oligonucleotides
US6737056B1 (en) 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
BR0008758A (pt) 1999-01-15 2001-12-04 Genentech Inc Variantes de polipeptìdeos parentais com funçãoefetora alterada, polipeptìdeos, composição ácidonucleico isolado, vetor, célula hospedeira,método para produzir uma variante depolipeptìdeo, método para o tratamento de umadesordem em mamìferos e método para produziruma região fc variante
US7361740B2 (en) 2002-10-15 2008-04-22 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
PT1572744E (pt) 2002-12-16 2010-09-07 Genentech Inc Variantes de imunoglobulina e utilizações destas
BR122019012028B1 (pt) 2004-04-13 2023-09-26 F. Hoffmann-La Roche Ag Anticorpos anti-p-selectina, molécula de ácido nucléico, vetor, e composição
TWI380996B (zh) 2004-09-17 2013-01-01 Hoffmann La Roche 抗ox40l抗體
TWI323734B (en) 2005-08-19 2010-04-21 Abbott Lab Dual variable domain immunoglobulin and uses thereof
US7612181B2 (en) 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
WO2007044756A2 (en) 2005-10-11 2007-04-19 Icos Corporation Monoclonal antibodies recognizing human ccr8
WO2013131010A2 (en) 2012-03-02 2013-09-06 Icahn School Of Medicine At Mount Sinai Function of chemokine receptor ccr8 in melanoma metastasis
GB2519786A (en) 2013-10-30 2015-05-06 Sergej Michailovic Kiprijanov Multivalent antigen-binding protein molecules
ES2923641T3 (es) 2013-12-30 2022-09-29 Epimab Biotherapeutics Inc Inmunoglobulina con Fabs en tándem y usos de la misma
US9300829B2 (en) 2014-04-04 2016-03-29 Canon Kabushiki Kaisha Image reading apparatus and correction method thereof
WO2018112032A1 (en) * 2016-12-13 2018-06-21 President And Fellows Of Harvard College Methods and compositions for targeting tumor-infiltrating tregs using inhibitors of ccr8 and tnfrsf8
EP3431105B1 (en) * 2017-03-29 2020-01-01 Shionogi&Co., Ltd. Medicinal composition for treating cancer
WO2019157098A1 (en) * 2018-02-06 2019-08-15 Advaxis, Inc. Compositions comprising a recombinant listeria strain and an anti-ccr8 antibody and methods of use
TWI845803B (zh) 2020-01-06 2024-06-21 美商法西尼克斯股份有限公司 抗ccr8抗體及其用途

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