JP2017522284A5 - - Google Patents

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Publication number
JP2017522284A5
JP2017522284A5 JP2016572799A JP2016572799A JP2017522284A5 JP 2017522284 A5 JP2017522284 A5 JP 2017522284A5 JP 2016572799 A JP2016572799 A JP 2016572799A JP 2016572799 A JP2016572799 A JP 2016572799A JP 2017522284 A5 JP2017522284 A5 JP 2017522284A5
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JP
Japan
Prior art keywords
methyl
cyclohexyl
potassium
carbonate
hydroxide
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JP2016572799A
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English (en)
Japanese (ja)
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JP6594351B2 (ja
JP2017522284A (ja
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Priority claimed from PCT/US2015/035558 external-priority patent/WO2015195478A1/en
Publication of JP2017522284A publication Critical patent/JP2017522284A/ja
Publication of JP2017522284A5 publication Critical patent/JP2017522284A5/ja
Application granted granted Critical
Publication of JP6594351B2 publication Critical patent/JP6594351B2/ja
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JP2016572799A 2014-06-16 2015-06-12 新規中間体を含むアルキル化アリールピペラジン及びアルキル化アリールピペリジン化合物の製造方法 Active JP6594351B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462012701P 2014-06-16 2014-06-16
US62/012,701 2014-06-16
PCT/US2015/035558 WO2015195478A1 (en) 2014-06-16 2015-06-12 Processes for making alkylated arylpiperazine and alkylated arylpiperidine compounds including novel intermediates

Publications (3)

Publication Number Publication Date
JP2017522284A JP2017522284A (ja) 2017-08-10
JP2017522284A5 true JP2017522284A5 (enExample) 2019-03-14
JP6594351B2 JP6594351B2 (ja) 2019-10-23

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ID=54835598

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016572799A Active JP6594351B2 (ja) 2014-06-16 2015-06-12 新規中間体を含むアルキル化アリールピペラジン及びアルキル化アリールピペリジン化合物の製造方法

Country Status (10)

Country Link
US (3) US9790237B2 (enExample)
EP (1) EP3154967B1 (enExample)
JP (1) JP6594351B2 (enExample)
CA (1) CA2951917C (enExample)
ES (1) ES2826603T3 (enExample)
HR (1) HRP20201638T1 (enExample)
HU (1) HUE052277T2 (enExample)
PL (1) PL3154967T3 (enExample)
SI (1) SI3154967T1 (enExample)
WO (1) WO2015195478A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL233778B1 (pl) 2016-07-19 2019-11-29 Adamed Spolka Z Ograniczona Odpowiedzialnoscia Sposob wytwarzania brekspiprazolu oraz zastosowanie zwiazkow posrednich w sposobie wytwarzania brekspiprazolu
US20210393621A1 (en) 2018-10-26 2021-12-23 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
CN116848108A (zh) * 2021-03-31 2023-10-03 四川科伦药物研究院有限公司 一种鲁拉西酮可注射混悬液及其制备方法
CN115073444A (zh) * 2022-08-05 2022-09-20 山东科源制药股份有限公司 一种盐酸鲁拉西酮环氧杂质的精制去除方法

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DE967826C (de) 1954-06-14 1957-12-19 Henkel & Cie Gmbh Verfahren zur Herstellung von Aryloxyalkanol-schwefelsaeurehalbestersalzen
GB1511159A (en) * 1975-07-10 1978-05-17 Leo A Amines preparation
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JP2800953B2 (ja) 1990-07-06 1998-09-21 住友製薬株式会社 新規なイミド誘導体
US5159100A (en) 1990-12-19 1992-10-27 Lonza Ltd. Process for the production of cyclopropanenitrile derivatives
US6467121B1 (en) 2000-08-15 2002-10-22 Goodway Technologies Corporation Rotary tube scrubber
UA79300C2 (en) 2002-08-12 2007-06-11 Janssen Pharmaceutica Nv N-aryl piperidine substituted biphenylcarboxamides as inhibitors of apolipoprotein b secretion
EP1535616B1 (en) 2002-08-22 2009-05-13 Dainippon Sumitomo Pharma Co., Ltd. Remedy for integration dysfunction syndrome
KR101085806B1 (ko) 2003-07-29 2011-11-22 다이닛본 스미토모 세이야꾸 가부시끼가이샤 이미드 화합물의 제조 방법
EP1660428A1 (en) * 2003-08-20 2006-05-31 Eli Lilly And Company Ppar modulators
EP1660472A1 (en) 2003-08-27 2006-05-31 Janssen Pharmaceutica N.V. Aryl piperidine amides
US20070160537A1 (en) 2004-02-20 2007-07-12 Takeo Ishiyama In vivo screening method of therapeutic agent for memory/learning dysfunctions by schizophrenia
US8283352B2 (en) 2005-06-13 2012-10-09 Dainippon Sumitomo Pharma Co., Ltd. Solubilization preparation
ES2356098T3 (es) 2006-08-17 2011-04-04 F. Hoffmann-La Roche Ag Derivados de arilpiperazina y usos de los mismos.
US20090076027A1 (en) 2007-09-17 2009-03-19 Protia, Llc Deuterium-enriched lurasidone
CN101868228B (zh) 2007-11-21 2016-12-07 大日本住友制药株式会社 口腔内崩解片
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WO2012063246A1 (en) 2010-11-11 2012-05-18 Mapi Pharma Ltd. Amorphous form of lurasidone hydrochloride
WO2012107890A2 (en) 2011-02-10 2012-08-16 Ranbaxy Laboratories Limited Crystalline forms of lurasidone hydrochloride
WO2012123858A1 (en) 2011-03-14 2012-09-20 Ranbaxy Laboratories Limited Amorphous lurasidone hydrochloride
WO2012131606A1 (en) 2011-04-01 2012-10-04 Ranbaxy Laboratories Limited Process for the preparation of an antipsychotic agent
CA2836066A1 (en) 2011-05-13 2012-11-22 Dainippon Sumitomo Pharma Co., Ltd. Treatment and management of cns disorders
US8981095B2 (en) * 2011-07-28 2015-03-17 Mapi Pharma Ltd. Intermediate compounds and process for the preparation of lurasidone and salts thereof
WO2013030722A1 (en) 2011-08-26 2013-03-07 Ranbaxy Laboratories Limited Crystalline lurasidone hydrochloride

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