JP2017522284A5 - - Google Patents

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Publication number
JP2017522284A5
JP2017522284A5 JP2016572799A JP2016572799A JP2017522284A5 JP 2017522284 A5 JP2017522284 A5 JP 2017522284A5 JP 2016572799 A JP2016572799 A JP 2016572799A JP 2016572799 A JP2016572799 A JP 2016572799A JP 2017522284 A5 JP2017522284 A5 JP 2017522284A5
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JP
Japan
Prior art keywords
methyl
cyclohexyl
potassium
carbonate
hydroxide
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JP2016572799A
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English (en)
Japanese (ja)
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JP6594351B2 (ja
JP2017522284A (ja
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Priority claimed from PCT/US2015/035558 external-priority patent/WO2015195478A1/en
Publication of JP2017522284A publication Critical patent/JP2017522284A/ja
Publication of JP2017522284A5 publication Critical patent/JP2017522284A5/ja
Application granted granted Critical
Publication of JP6594351B2 publication Critical patent/JP6594351B2/ja
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JP2016572799A 2014-06-16 2015-06-12 新規中間体を含むアルキル化アリールピペラジン及びアルキル化アリールピペリジン化合物の製造方法 Active JP6594351B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462012701P 2014-06-16 2014-06-16
US62/012,701 2014-06-16
PCT/US2015/035558 WO2015195478A1 (en) 2014-06-16 2015-06-12 Processes for making alkylated arylpiperazine and alkylated arylpiperidine compounds including novel intermediates

Publications (3)

Publication Number Publication Date
JP2017522284A JP2017522284A (ja) 2017-08-10
JP2017522284A5 true JP2017522284A5 (enExample) 2019-03-14
JP6594351B2 JP6594351B2 (ja) 2019-10-23

Family

ID=54835598

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016572799A Active JP6594351B2 (ja) 2014-06-16 2015-06-12 新規中間体を含むアルキル化アリールピペラジン及びアルキル化アリールピペリジン化合物の製造方法

Country Status (10)

Country Link
US (3) US9790237B2 (enExample)
EP (1) EP3154967B1 (enExample)
JP (1) JP6594351B2 (enExample)
CA (1) CA2951917C (enExample)
ES (1) ES2826603T3 (enExample)
HR (1) HRP20201638T1 (enExample)
HU (1) HUE052277T2 (enExample)
PL (1) PL3154967T3 (enExample)
SI (1) SI3154967T1 (enExample)
WO (1) WO2015195478A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL233778B1 (pl) 2016-07-19 2019-11-29 Adamed Spolka Z Ograniczona Odpowiedzialnoscia Sposob wytwarzania brekspiprazolu oraz zastosowanie zwiazkow posrednich w sposobie wytwarzania brekspiprazolu
US20210393621A1 (en) 2018-10-26 2021-12-23 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
WO2022206447A1 (zh) * 2021-03-31 2022-10-06 四川科伦药物研究院有限公司 一种鲁拉西酮可注射混悬液及其制备方法
CN115073444A (zh) * 2022-08-05 2022-09-20 山东科源制药股份有限公司 一种盐酸鲁拉西酮环氧杂质的精制去除方法

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DE967826C (de) 1954-06-14 1957-12-19 Henkel & Cie Gmbh Verfahren zur Herstellung von Aryloxyalkanol-schwefelsaeurehalbestersalzen
GB1511159A (en) * 1975-07-10 1978-05-17 Leo A Amines preparation
HU207310B (en) 1988-12-02 1993-03-29 Pfizer Process for producing aryl-piperidine derivatives
JP2800953B2 (ja) 1990-07-06 1998-09-21 住友製薬株式会社 新規なイミド誘導体
US5159100A (en) 1990-12-19 1992-10-27 Lonza Ltd. Process for the production of cyclopropanenitrile derivatives
US6467121B1 (en) 2000-08-15 2002-10-22 Goodway Technologies Corporation Rotary tube scrubber
UA79300C2 (en) 2002-08-12 2007-06-11 Janssen Pharmaceutica Nv N-aryl piperidine substituted biphenylcarboxamides as inhibitors of apolipoprotein b secretion
ES2685780T3 (es) 2002-08-22 2018-10-11 Sumitomo Dainippon Pharma Co., Ltd. Agente para el tratamiento de esquizofrenia
BRPI0413081B8 (pt) 2003-07-29 2021-05-25 Dainippon Sumitomo Pharma Co processo para produzir o cloridrato do composto imida
JP2007502815A (ja) * 2003-08-20 2007-02-15 イーライ リリー アンド カンパニー Ｐｐａｒ調節因子
WO2005021525A1 (en) 2003-08-27 2005-03-10 Janssen Pharmaceutica, N.V. Aryl piperidine amides
EP1726952A4 (en) 2004-02-20 2008-06-18 Dainippon Sumitomo Pharma Co METHOD FOR IN VIVO SCREENING OF A THERAPEUTIC FOR A MEMORY / LEARNING FUNCTION THROUGH SCHIZOPHRENIA
EP1891956B1 (en) 2005-06-13 2012-08-29 Dainippon Sumitomo Pharma Co., Ltd. Solubilization preparation
ATE492539T1 (de) 2006-08-17 2011-01-15 Hoffmann La Roche Arylpiperazinderivate und anwendungen davon
US20090076027A1 (en) 2007-09-17 2009-03-19 Protia, Llc Deuterium-enriched lurasidone
CN101868228B (zh) 2007-11-21 2016-12-07 大日本住友制药株式会社 口腔内崩解片
US8735397B2 (en) 2010-03-29 2014-05-27 Vanderbilt University Method for treating schizophrenia and related diseases
WO2011136383A1 (en) 2010-04-26 2011-11-03 Dainippon Sumitomo Pharma Co., Ltd. A process of a quaternary ammonium salt
JP5820822B2 (ja) 2010-04-26 2015-11-24 大日本住友製薬株式会社 リン酸塩を用いる第四級アンモニウム塩の製造法
US8258139B2 (en) 2010-11-08 2012-09-04 Dainippon Sumitomo Pharma Co., Ltd. Method of treatment for mental disorders
WO2012063246A1 (en) 2010-11-11 2012-05-18 Mapi Pharma Ltd. Amorphous form of lurasidone hydrochloride
WO2012107890A2 (en) 2011-02-10 2012-08-16 Ranbaxy Laboratories Limited Crystalline forms of lurasidone hydrochloride
WO2012123858A1 (en) 2011-03-14 2012-09-20 Ranbaxy Laboratories Limited Amorphous lurasidone hydrochloride
WO2012131606A1 (en) 2011-04-01 2012-10-04 Ranbaxy Laboratories Limited Process for the preparation of an antipsychotic agent
CA2836066A1 (en) 2011-05-13 2012-11-22 Dainippon Sumitomo Pharma Co., Ltd. Treatment and management of cns disorders
EP2736905A4 (en) * 2011-07-28 2015-07-29 Mapi Pharma Ltd INTERMEDIATE COMPOUNDS AND PROCESS FOR THE PREPARATION OF LURASIDONE AND SALTS THEREOF
WO2013030722A1 (en) 2011-08-26 2013-03-07 Ranbaxy Laboratories Limited Crystalline lurasidone hydrochloride

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