JP2017517745A5 - - Google Patents

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JP2017517745A5
JP2017517745A5 JP2017500408A JP2017500408A JP2017517745A5 JP 2017517745 A5 JP2017517745 A5 JP 2017517745A5 JP 2017500408 A JP2017500408 A JP 2017500408A JP 2017500408 A JP2017500408 A JP 2017500408A JP 2017517745 A5 JP2017517745 A5 JP 2017517745A5
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antibody
retention time
value
region
determining
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JP2017500408A
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JP6744855B2 (ja
JP2017517745A (ja
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Priority claimed from PCT/EP2015/055482 external-priority patent/WO2015140126A1/en
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JP2017500408A 2014-03-21 2015-03-17 抗体のin vivoでの半減期のin vitroでの予測 Active JP6744855B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP14161103 2014-03-21
EP14161103.8 2014-03-21
EP14165987 2014-04-25
EP14165987.0 2014-04-25
PCT/EP2015/055482 WO2015140126A1 (en) 2014-03-21 2015-03-17 In vitro prediction of in vivo half-life of antibodies

Related Child Applications (1)

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JP2020129979A Division JP7032490B2 (ja) 2014-03-21 2020-07-31 抗体のin vivoでの半減期のin vitroでの予測

Publications (3)

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JP2017517745A JP2017517745A (ja) 2017-06-29
JP2017517745A5 true JP2017517745A5 (OSRAM) 2018-04-12
JP6744855B2 JP6744855B2 (ja) 2020-08-19

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JP2017500408A Active JP6744855B2 (ja) 2014-03-21 2015-03-17 抗体のin vivoでの半減期のin vitroでの予測
JP2020129979A Active JP7032490B2 (ja) 2014-03-21 2020-07-31 抗体のin vivoでの半減期のin vitroでの予測

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US (2) US20170227547A1 (OSRAM)
EP (1) EP3119490B1 (OSRAM)
JP (2) JP6744855B2 (OSRAM)
KR (1) KR20160134687A (OSRAM)
CN (1) CN106103478B (OSRAM)
BR (1) BR112016023417A2 (OSRAM)
CA (1) CA2938722A1 (OSRAM)
MX (1) MX377315B (OSRAM)
RU (1) RU2688349C2 (OSRAM)
WO (1) WO2015140126A1 (OSRAM)

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CN106957365B (zh) * 2016-01-11 2021-03-16 上海交通大学 一种单克隆抗体FnAb8及其应用
CN106957364B (zh) * 2016-01-11 2021-03-16 上海交通大学 一种单克隆抗体FnAb12及其应用
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JP2022511396A (ja) 2018-10-01 2022-01-31 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト Cd40への三価結合を伴う二重特異性抗原結合分子
SG11202102477QA (en) 2018-10-01 2021-04-29 Hoffmann La Roche Bispecific antigen binding molecules comprising anti-fap clone 212
JP2022512798A (ja) 2018-10-25 2022-02-07 エフ.ホフマン-ラ ロシュ アーゲー 抗体FcRn結合の改変
CN113227134A (zh) 2018-12-05 2021-08-06 株式会社梅花治疗 抗体的Fc区变体
CN113227789B (zh) * 2018-12-30 2024-12-24 豪夫迈·罗氏有限公司 基于pH梯度SPR的结合测定
AR121706A1 (es) 2020-04-01 2022-06-29 Hoffmann La Roche Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap
EP4133269A1 (en) * 2020-04-08 2023-02-15 F. Hoffmann-La Roche AG Large molecule unspecific clearance assay
JP7322858B2 (ja) * 2020-11-02 2023-08-08 株式会社三洋物産 遊技機
JP7322857B2 (ja) * 2020-11-02 2023-08-08 株式会社三洋物産 遊技機
CN113308476B (zh) * 2021-05-12 2022-06-28 广东药康生物科技有限公司 一种FcRn基因人源化动物模型的构建方法
US20250076283A1 (en) * 2021-05-19 2025-03-06 Chugai Seiyaku Kabushiki Kaisha Method for predicting in vivo pharmacokinetics of molecule
TW202535933A (zh) * 2023-10-25 2025-09-16 美商多重宇宙製藥公司 靶向il-12及il-23之抗原結合分子
WO2025224705A1 (en) * 2024-04-26 2025-10-30 Waters Technologies Corporation Direct affinity to size-exclusion chromatography methods and systems thereof

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JP6832709B2 (ja) 2014-05-16 2021-02-24 メディミューン,エルエルシー 新生児Fc受容体結合が改変されて治療および診断特性が強化された分子
BR112017006178A2 (pt) 2014-11-06 2018-05-02 F. Hoffmann-La Roche Ag região fc, anticorpos, formulação farmacêutica e usos dos anticorpos

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