JP2017510567A5 - - Google Patents
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- Publication number
- JP2017510567A5 JP2017510567A5 JP2016555690A JP2016555690A JP2017510567A5 JP 2017510567 A5 JP2017510567 A5 JP 2017510567A5 JP 2016555690 A JP2016555690 A JP 2016555690A JP 2016555690 A JP2016555690 A JP 2016555690A JP 2017510567 A5 JP2017510567 A5 JP 2017510567A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- mcam
- amino acid
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461952116P | 2014-03-12 | 2014-03-12 | |
| US61/952,116 | 2014-03-12 | ||
| US201461952833P | 2014-03-13 | 2014-03-13 | |
| US61/952,833 | 2014-03-13 | ||
| US201462023724P | 2014-07-11 | 2014-07-11 | |
| US62/023,724 | 2014-07-11 | ||
| US201462068419P | 2014-10-24 | 2014-10-24 | |
| US62/068,419 | 2014-10-24 | ||
| PCT/IB2015/051787 WO2015136470A1 (en) | 2014-03-12 | 2015-03-12 | Anti-mcam antibodies and associated methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017510567A JP2017510567A (ja) | 2017-04-13 |
| JP2017510567A5 true JP2017510567A5 (enExample) | 2018-03-29 |
Family
ID=52823724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016555690A Pending JP2017510567A (ja) | 2014-03-12 | 2015-03-12 | 抗ｍｃａｍ抗体および関連の使用方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20150259419A1 (enExample) |
| EP (1) | EP3116912A1 (enExample) |
| JP (1) | JP2017510567A (enExample) |
| KR (1) | KR20160131061A (enExample) |
| CN (1) | CN106132990A (enExample) |
| AU (1) | AU2015228454A1 (enExample) |
| BR (1) | BR112016020871A2 (enExample) |
| CA (1) | CA2942233A1 (enExample) |
| CL (1) | CL2016002257A1 (enExample) |
| CU (1) | CU20160133A7 (enExample) |
| EA (1) | EA201691836A1 (enExample) |
| IL (1) | IL247754A0 (enExample) |
| MX (1) | MX2016011731A (enExample) |
| PE (1) | PE20161210A1 (enExample) |
| PH (1) | PH12016501760A1 (enExample) |
| SG (1) | SG11201606274XA (enExample) |
| TW (1) | TW201623331A (enExample) |
| WO (1) | WO2015136470A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI660972B (zh) | 2012-09-10 | 2019-06-01 | 愛爾蘭商尼歐托普生物科學公司 | 抗ｍｃａｍ抗體及相關使用方法 |
| US10059761B2 (en) | 2014-03-12 | 2018-08-28 | Prothena Biosciences Limited | Anti-Laminin4 antibodies specific for LG4-5 |
| PT3116911T (pt) | 2014-03-12 | 2019-09-04 | Prothena Biosciences Ltd | Anticorpos anti-mcam e métodos de utilização associados |
| JP2018530540A (ja) * | 2015-09-16 | 2018-10-18 | プロセナ バイオサイエンシーズ リミテッド | 巨細胞動脈炎、リウマチ性多発筋痛症又は高安動脈炎の処置又は予防のための抗ｍｃａｍ抗体の使用 |
| WO2017075173A2 (en) * | 2015-10-30 | 2017-05-04 | Genentech, Inc. | Anti-factor d antibodies and conjugates |
| WO2017149513A1 (en) | 2016-03-03 | 2017-09-08 | Prothena Biosciences Limited | Anti-mcam antibodies and associated methods of use |
| WO2017208210A1 (en) | 2016-06-03 | 2017-12-07 | Prothena Biosciences Limited | Anti-mcam antibodies and associated methods of use |
| WO2018124277A1 (ja) * | 2016-12-28 | 2018-07-05 | Ｊｃｒファーマ株式会社 | 凍結乾燥製剤 |
| JOP20210229A1 (ar) | 2019-02-18 | 2023-01-30 | Lilly Co Eli | صيغة جسم مضاد علاجي |
| WO2022133169A1 (en) | 2020-12-18 | 2022-06-23 | Century Therapeutics, Inc. | Chimeric antigen receptor systems with adaptable receptor specificity |
| EP4463135A2 (en) | 2022-01-10 | 2024-11-20 | Sana Biotechnology, Inc. | Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses |
| WO2024081820A1 (en) | 2022-10-13 | 2024-04-18 | Sana Biotechnology, Inc. | Viral particles targeting hematopoietic stem cells |
| WO2024119157A1 (en) | 2022-12-02 | 2024-06-06 | Sana Biotechnology, Inc. | Lipid particles with cofusogens and methods of producing and using the same |
| TW202440636A (zh) | 2023-03-21 | 2024-10-16 | 美商傳記５５有限公司 | Ｃｄ１９／ｃｄ３８多特異性抗體 |
| AU2024274792A1 (en) | 2023-05-23 | 2025-10-23 | Sana Biotechnology, Inc. | Tandem fusogens and related lipid particles |
| CN117069848B (zh) * | 2023-08-02 | 2025-02-28 | 武汉爱博泰克生物科技有限公司 | 抗人cd146兔单克隆抗体及其应用 |
| WO2025184529A1 (en) | 2024-03-01 | 2025-09-04 | Sana Biotechnology, Inc. | Viral particles with fusogen display and related compositions and methods |
| CN119192349A (zh) * | 2024-07-18 | 2024-12-27 | 北京市延庆区疾病预防控制中心 | 用于检测黄连素抗性病毒的试剂及方法 |
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| CH652145A5 (de) | 1982-01-22 | 1985-10-31 | Sandoz Ag | Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen. |
| US4634666A (en) | 1984-01-06 | 1987-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | Human-murine hybridoma fusion partner |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・２・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| SG48759A1 (en) | 1990-01-12 | 2002-07-23 | Abgenix Inc | Generation of xenogenic antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| ES2246502T3 (es) | 1990-08-29 | 2006-02-16 | Genpharm International, Inc. | Animales no humanos transgenicos capaces de producir anticuerpos heterologos. |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5874299A (en) | 1990-08-29 | 1999-02-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5194594A (en) | 1990-09-07 | 1993-03-16 | Techniclone, Inc. | Modified antibodies |
| DE69230142T2 (de) | 1991-05-15 | 2000-03-09 | Cambridge Antibody Technology Ltd. | Verfahren zur herstellung von spezifischen bindungspaargliedern |
| US5858657A (en) | 1992-05-15 | 1999-01-12 | Medical Research Council | Methods for producing members of specific binding pairs |
| JP4124480B2 (ja) | 1991-06-14 | 2008-07-23 | ジェネンテック・インコーポレーテッド | 免疫グロブリン変異体 |
| ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
| CA2124967C (en) | 1991-12-17 | 2008-04-08 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| CA2150262C (en) | 1992-12-04 | 2008-07-08 | Kaspar-Philipp Holliger | Multivalent and multispecific binding proteins, their manufacture and use |
| US5914349A (en) | 1994-01-10 | 1999-06-22 | Teva Pharmaceutical Industries, Ltd. | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives |
| US5786464C1 (en) | 1994-09-19 | 2012-04-24 | Gen Hospital Corp | Overexpression of mammalian and viral proteins |
| DE19539493A1 (de) | 1995-10-24 | 1997-04-30 | Thomae Gmbh Dr K | Starker homologer Promotor aus Hamster |
| US5834597A (en) | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| US6114148C1 (en) | 1996-09-20 | 2012-05-01 | Gen Hospital Corp | High level expression of proteins |
| CA2283557A1 (en) | 1997-03-10 | 1998-09-17 | Heather L. Davis | Use of nucleic acids containing unmethylated cpg dinucleotide as an adjuvant |
| US5888809A (en) | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
| CN100405399C (zh) | 1999-02-05 | 2008-07-23 | 三星电子株式会社 | 图像纹理恢复方法及其装置 |
| WO2004006955A1 (en) | 2001-07-12 | 2004-01-22 | Jefferson Foote | Super humanized antibodies |
| ATE454137T1 (de) * | 2001-07-25 | 2010-01-15 | Facet Biotech Corp | Stabile lyophilisierte pharmazeutische formulierung des igg-antikörpers daclizumab |
| JP2005516965A (ja) | 2001-12-28 | 2005-06-09 | アブジェニックス・インコーポレーテッド | 抗ｍｕｃ１８抗体を使用する方法 |
| CA2472154A1 (en) | 2001-12-28 | 2003-07-17 | Abgenix, Inc. | Use of antibodies against the muc18 antigen |
| ES2289174T3 (es) | 2001-12-28 | 2008-02-01 | Amgen Fremont Inc. | Anticuerpos contra el antigeno muc-18. |
| CN101914158A (zh) * | 2002-02-14 | 2010-12-15 | 免疫医疗公司 | 抗cd 20抗体及其融合蛋白和使用方法 |
| EP1382615A1 (en) * | 2002-07-15 | 2004-01-21 | Xerion Pharmaceuticals AG | MCAM inhibitors |
| ES2293096T3 (es) | 2002-11-29 | 2008-03-16 | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG | Nuevos genes de la fosfotransferasa de neomicina y procedimiento para la seleccion de celulas recombinantes de produccion elevada. |
| DE10338531A1 (de) | 2003-08-19 | 2005-04-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Reklonierung von Produktionszellen |
| DK1787126T3 (da) * | 2004-07-20 | 2009-12-21 | Symphogen As | Fremgangsmåde til karakterisering af en polyklonal cellelinie |
| DK1820022T3 (da) | 2004-11-10 | 2009-09-14 | Boehringer Ingelheim Pharma | Anvendelse af flow-cytometrisk analyse for at optimere cellebanks-strategier af CHO-celler |
| US20080124760A1 (en) | 2006-07-26 | 2008-05-29 | Barbara Enenkel | Regulatory Nucleic Acid Elements |
| EP2099823B2 (en) | 2006-12-01 | 2022-02-09 | Seagen Inc. | Variant target binding agents and uses thereof |
| DK2126093T3 (da) | 2007-03-02 | 2013-01-07 | Boehringer Ingelheim Pharma | Forbedring af proteinfremstilling |
| EP2031064A1 (de) | 2007-08-29 | 2009-03-04 | Boehringer Ingelheim Pharma GmbH & Co. KG | Verfahren zur Steigerung von Proteintitern |
| MX2012004412A (es) * | 2009-10-15 | 2012-05-08 | Abbott Lab | Proteinas de union a il-1. |
| AR079944A1 (es) * | 2010-01-20 | 2012-02-29 | Boehringer Ingelheim Int | Anticuerpo neutralizante de la actividad de un anticoagulante |
| US8974782B2 (en) * | 2011-02-07 | 2015-03-10 | Glaxo Group Limited | Treatment of stroke comprising anti-MAG antibodies |
| US20140314744A1 (en) * | 2011-06-06 | 2014-10-23 | Neotope Biosciences Limited | Mcam antagonists and methods of treatment |
| US20140335084A1 (en) * | 2011-12-06 | 2014-11-13 | Hoffmann-La Roche Inc. | Antibody formulation |
| TWI660972B (zh) * | 2012-09-10 | 2019-06-01 | 愛爾蘭商尼歐托普生物科學公司 | 抗ｍｃａｍ抗體及相關使用方法 |
-
2015
- 2015-03-10 TW TW104107585A patent/TW201623331A/zh unknown
- 2015-03-12 PE PE2016001594A patent/PE20161210A1/es not_active Application Discontinuation
- 2015-03-12 BR BR112016020871A patent/BR112016020871A2/pt not_active Application Discontinuation
- 2015-03-12 EP EP15712430.6A patent/EP3116912A1/en not_active Withdrawn
- 2015-03-12 CA CA2942233A patent/CA2942233A1/en not_active Abandoned
- 2015-03-12 US US14/656,596 patent/US20150259419A1/en not_active Abandoned
- 2015-03-12 EA EA201691836A patent/EA201691836A1/ru unknown
- 2015-03-12 MX MX2016011731A patent/MX2016011731A/es unknown
- 2015-03-12 KR KR1020167027673A patent/KR20160131061A/ko not_active Withdrawn
- 2015-03-12 JP JP2016555690A patent/JP2017510567A/ja active Pending
- 2015-03-12 AU AU2015228454A patent/AU2015228454A1/en not_active Abandoned
- 2015-03-12 CN CN201580013418.9A patent/CN106132990A/zh active Pending
- 2015-03-12 WO PCT/IB2015/051787 patent/WO2015136470A1/en not_active Ceased
- 2015-03-12 SG SG11201606274XA patent/SG11201606274XA/en unknown
-
2016
- 2016-09-07 CL CL2016002257A patent/CL2016002257A1/es unknown
- 2016-09-07 PH PH12016501760A patent/PH12016501760A1/en unknown
- 2016-09-11 IL IL247754A patent/IL247754A0/en unknown
- 2016-09-12 CU CUP2016000133A patent/CU20160133A7/es unknown
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