JP2017508796A5 - - Google Patents
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- JP2017508796A5 JP2017508796A5 JP2016573684A JP2016573684A JP2017508796A5 JP 2017508796 A5 JP2017508796 A5 JP 2017508796A5 JP 2016573684 A JP2016573684 A JP 2016573684A JP 2016573684 A JP2016573684 A JP 2016573684A JP 2017508796 A5 JP2017508796 A5 JP 2017508796A5
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- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- substituted
- compound
- iron
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461949733P | 2014-03-07 | 2014-03-07 | |
| US61/949,733 | 2014-03-07 | ||
| PCT/US2015/018886 WO2015134710A1 (en) | 2014-03-07 | 2015-03-05 | Propellane derivates and synthesis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020038074A Division JP2020094059A (ja) | 2014-03-07 | 2020-03-05 | プロペラン誘導体および合成 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017508796A JP2017508796A (ja) | 2017-03-30 |
| JP2017508796A5 true JP2017508796A5 (https=) | 2018-04-12 |
| JP6741343B2 JP6741343B2 (ja) | 2020-08-19 |
Family
ID=54055863
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016573684A Expired - Fee Related JP6741343B2 (ja) | 2014-03-07 | 2015-03-05 | プロペラン誘導体および合成 |
| JP2020038074A Withdrawn JP2020094059A (ja) | 2014-03-07 | 2020-03-05 | プロペラン誘導体および合成 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020038074A Withdrawn JP2020094059A (ja) | 2014-03-07 | 2020-03-05 | プロペラン誘導体および合成 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10654812B2 (https=) |
| EP (1) | EP3114107B1 (https=) |
| JP (2) | JP6741343B2 (https=) |
| KR (1) | KR102401840B1 (https=) |
| CN (2) | CN113336653A (https=) |
| CA (1) | CA2942144C (https=) |
| TW (1) | TWI671281B (https=) |
| WO (1) | WO2015134710A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102243637B1 (ko) | 2013-03-14 | 2021-04-26 | 리커리엄 아이피 홀딩스, 엘엘씨 | 바이사이클릭 진통 화합물 |
| CN108947867A (zh) | 2013-12-12 | 2018-12-07 | 卡利拉制药公司 | 双环烷基化合物及合成 |
| CA2942144C (en) | 2014-03-07 | 2023-08-22 | Kalyra Pharmaceuticals, Inc. | Propellane derivates and synthesis |
| CN106999451B (zh) * | 2014-09-17 | 2021-04-02 | 里科瑞尔姆Ip控股有限责任公司 | 双环化合物 |
| KR101974793B1 (ko) | 2015-07-06 | 2019-05-02 | 길리애드 사이언시즈, 인코포레이티드 | Cot 조정제 및 그의 사용 방법 |
| KR102444836B1 (ko) | 2016-08-23 | 2022-09-19 | 리커리엄 아이피 홀딩스, 엘엘씨 | 교차 커플링 방법 |
| JP7128816B2 (ja) | 2016-12-08 | 2022-08-31 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | 疾患の治療のための二重ロイシンジッパー（ｄｌｋ）キナーゼのビシクロ［１．１．１］ペンタン阻害剤 |
| EP3628043A4 (en) | 2017-05-15 | 2021-04-28 | Recurium IP Holdings, LLC | ANALGESIC COMPOUNDS |
| SG11202001733VA (en) * | 2017-09-11 | 2020-03-30 | Recurium Ip Holdings Llc | Continuous flow processes for making bicyclic compounds |
| US20190382396A1 (en) * | 2018-06-13 | 2019-12-19 | Board Of Regents, The University Of Texas System | Salts of bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (dlk) kinase for the treatment of disease |
| CN109456332B (zh) * | 2018-08-16 | 2021-11-26 | 北京理工大学 | 一种稳定的氮杂[3.3.3]螺桨烷卡宾及其制备方法 |
| TWI770527B (zh) | 2019-06-14 | 2022-07-11 | 美商基利科學股份有限公司 | Cot 調節劑及其使用方法 |
| US11560366B2 (en) | 2019-10-21 | 2023-01-24 | Board Of Regents, The University Of Texas System | Bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of disease |
| AU2021249010B2 (en) | 2020-03-30 | 2024-09-26 | Gilead Sciences, Inc. | Solid forms of (S)-6-(((1-(bicyclo[1.1.1]pentan-1-yl)-1H-1,2,3-triazol-4-yl)2-methyl-1-oxo-1,2- dihydroisoquinolin-5-yl)methyl)))amino)8-chloro-(neopentylamino)quinoline-3-carb onitrile a cot inhibitor compound |
| JP7446475B2 (ja) | 2020-04-02 | 2024-03-08 | ギリアード サイエンシーズ， インコーポレイテッド | Ｃｏｔ阻害剤化合物を調製するためのプロセス |
| US20230322573A1 (en) * | 2020-08-14 | 2023-10-12 | Board Of Regents, The University Of Texas System | Catalytically enhanced production of aluminum chlorohydrates |
| CN113264843B (zh) * | 2021-04-15 | 2022-09-27 | 台州学院 | 一种3-氨基二环[1.1.1]戊烷-1-羧酸酯类衍生物的合成方法 |
| CN114591137B (zh) * | 2022-05-10 | 2022-09-09 | 上海赛默罗生物科技有限公司 | 螺桨烷类衍生物的合成方法 |
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| US5404550A (en) | 1991-07-25 | 1995-04-04 | Tandem Computers Incorporated | Method and apparatus for executing tasks by following a linked list of memory packets |
| JPH07110559A (ja) * | 1993-10-12 | 1995-04-25 | Fuji Photo Film Co Ltd | ハロゲン化銀カラー写真感光材料 |
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| AU3898000A (en) | 1999-03-19 | 2000-10-09 | Knoll Pharmaceutical Company | Treatment of neuropathic pain or fibromyalgia |
| DE10025946A1 (de) | 2000-05-26 | 2001-11-29 | Gruenenthal Gmbh | Wirkstoffkombination |
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| SMT202400031T1 (it) | 2011-04-22 | 2024-03-13 | Signal Pharm Llc | Diamminocarbossammide e diamminocarbonitrile pirimidine sostituite, loro composizioni e metodi di trattamento con esse |
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| BR112016008632A8 (pt) | 2013-10-21 | 2020-03-17 | Merck Patent Gmbh | compostos de heteroarila como inibidores de btk, seus usos, e composição farmacêutica |
| CN103588668A (zh) | 2013-10-28 | 2014-02-19 | 史克勇 | 化合物 |
| CN103588672A (zh) | 2013-10-28 | 2014-02-19 | 史克勇 | 一种治疗癌性疼痛的药物 |
| CN108947867A (zh) * | 2013-12-12 | 2018-12-07 | 卡利拉制药公司 | 双环烷基化合物及合成 |
| EP3082819B1 (en) | 2013-12-20 | 2020-06-17 | Signal Pharmaceuticals, LLC | Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith |
| CA2942144C (en) | 2014-03-07 | 2023-08-22 | Kalyra Pharmaceuticals, Inc. | Propellane derivates and synthesis |
| US20150291606A1 (en) | 2014-04-11 | 2015-10-15 | The University Of North Carolina At Chapel Hill | Mertk-specific pyrrolopyrimidine compounds |
| US20170197939A1 (en) | 2014-04-15 | 2017-07-13 | Pfizer Inc. | Tropomyosin-Related Kinase Inhibitors Containing Both A 1H-Pyrazole And A Pyrimidine Moiety |
| EP3134397A1 (en) | 2014-04-24 | 2017-03-01 | Novartis AG | Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors |
| CN107001283B (zh) | 2014-07-31 | 2021-05-25 | 国家健康与医学研究院 | Flt3受体拮抗剂 |
| CN106999451B (zh) | 2014-09-17 | 2021-04-02 | 里科瑞尔姆Ip控股有限责任公司 | 双环化合物 |
-
2015
- 2015-03-05 CA CA2942144A patent/CA2942144C/en active Active
- 2015-03-05 WO PCT/US2015/018886 patent/WO2015134710A1/en not_active Ceased
- 2015-03-05 KR KR1020167027508A patent/KR102401840B1/ko not_active Expired - Fee Related
- 2015-03-05 EP EP15757721.4A patent/EP3114107B1/en active Active
- 2015-03-05 JP JP2016573684A patent/JP6741343B2/ja not_active Expired - Fee Related
- 2015-03-05 CN CN202110430501.3A patent/CN113336653A/zh active Pending
- 2015-03-05 US US15/123,898 patent/US10654812B2/en active Active
- 2015-03-05 CN CN201580020861.9A patent/CN106232567B/zh active Active
- 2015-03-06 TW TW104107323A patent/TWI671281B/zh active
-
2020
- 2020-03-05 JP JP2020038074A patent/JP2020094059A/ja not_active Withdrawn
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