JP2017500893A - 細胞培養のための培地 - Google Patents

細胞培養のための培地 Download PDF

Info

Publication number
JP2017500893A
JP2017500893A JP2016560860A JP2016560860A JP2017500893A JP 2017500893 A JP2017500893 A JP 2017500893A JP 2016560860 A JP2016560860 A JP 2016560860A JP 2016560860 A JP2016560860 A JP 2016560860A JP 2017500893 A JP2017500893 A JP 2017500893A
Authority
JP
Japan
Prior art keywords
medium
cells
cell
serum replacement
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016560860A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017500893A5 (cg-RX-API-DMAC7.html
Inventor
アダム エルホフィー、
アダム エルホフィー、
アラン ウェーバー、
アラン ウェーバー、
Original Assignee
エッセンシャル ファーマシューティカル エルエルシー
エッセンシャル ファーマシューティカル エルエルシー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エッセンシャル ファーマシューティカル エルエルシー, エッセンシャル ファーマシューティカル エルエルシー filed Critical エッセンシャル ファーマシューティカル エルエルシー
Publication of JP2017500893A publication Critical patent/JP2017500893A/ja
Publication of JP2017500893A5 publication Critical patent/JP2017500893A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/35—Polyols, e.g. glycerin, inositol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/46—Amines, e.g. putrescine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure
    • C12N2500/62—DMSO
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/32—Polylysine, polyornithine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
JP2016560860A 2013-12-20 2014-12-19 細胞培養のための培地 Pending JP2017500893A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361918833P 2013-12-20 2013-12-20
US61/918,833 2013-12-20
PCT/US2014/071388 WO2015095651A1 (en) 2013-12-20 2014-12-19 Media for cell culture

Publications (2)

Publication Number Publication Date
JP2017500893A true JP2017500893A (ja) 2017-01-12
JP2017500893A5 JP2017500893A5 (cg-RX-API-DMAC7.html) 2018-02-08

Family

ID=53399356

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016560860A Pending JP2017500893A (ja) 2013-12-20 2014-12-19 細胞培養のための培地

Country Status (16)

Country Link
US (2) US9637721B2 (cg-RX-API-DMAC7.html)
EP (1) EP3083978A4 (cg-RX-API-DMAC7.html)
JP (1) JP2017500893A (cg-RX-API-DMAC7.html)
KR (1) KR20160125352A (cg-RX-API-DMAC7.html)
CN (1) CN106062205A (cg-RX-API-DMAC7.html)
AR (1) AR098875A1 (cg-RX-API-DMAC7.html)
AU (1) AU2014364368A1 (cg-RX-API-DMAC7.html)
BR (1) BR112016014488A2 (cg-RX-API-DMAC7.html)
CA (1) CA2934487A1 (cg-RX-API-DMAC7.html)
CL (1) CL2016001553A1 (cg-RX-API-DMAC7.html)
EA (1) EA201691297A1 (cg-RX-API-DMAC7.html)
IL (1) IL246262A0 (cg-RX-API-DMAC7.html)
MX (1) MX2016008251A (cg-RX-API-DMAC7.html)
SG (1) SG11201604994UA (cg-RX-API-DMAC7.html)
TW (1) TW201527534A (cg-RX-API-DMAC7.html)
WO (1) WO2015095651A1 (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020218584A1 (ja) * 2019-04-26 2020-10-29 味の素株式会社 細胞培養用組成物
WO2024024892A1 (ja) * 2022-07-28 2024-02-01 公立大学法人山陽小野田市立山口東京理科大学 凍結保存用の組成物、凍結保存方法、及び凍結した細胞又は生体組織

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015138832A1 (en) 2014-03-13 2015-09-17 The General Hospital Corporation Devices and methods to improve and assess viability of human livers
AU2015373050B2 (en) 2014-12-30 2022-09-29 Cell Cure Neurosciences Ltd. RPE cell populations and methods of generating same
JP6873985B2 (ja) 2015-10-15 2021-05-19 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ インビトロで肝臓構築物を産生する方法およびその使用
JP7011828B2 (ja) 2015-10-16 2022-01-27 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ 多層気道オルガノイドならびにそれを調製および使用する方法
US20180369336A1 (en) * 2015-12-03 2018-12-27 Boston Medical Center Corporation B cell-based cancer immunotherapy
CN105567628B (zh) * 2016-01-30 2019-07-12 令世鑫 一种全悬浮培养mdck细胞的低血清培养基
CN105695407B (zh) * 2016-03-15 2019-04-16 佰通生物技术(苏州)有限公司 一种对干细胞具有活化作用的微量元素组合物及其应用
US20190100725A1 (en) 2016-03-18 2019-04-04 Institute Of Biophysics, Chinese Academy Of Sciences Cell culture medium and culture medium supplement
TWI734775B (zh) 2016-04-26 2021-08-01 美商美國泰福生技股份有限公司 細胞培養基
CN106119186B (zh) * 2016-06-24 2019-10-08 肇庆大华农生物药品有限公司 一种用于全悬浮培养mdck细胞的无血清培养基及其制备方法
CN106497872B (zh) * 2016-12-01 2019-10-11 北京欣博睿丰医疗科技发展有限公司 骨骼肌干细胞无血清培养基及其制备方法和应用
WO2018144693A1 (en) * 2017-02-01 2018-08-09 Orig3N, Inc. Systems and methods for customizing cell culture media for optimized cell proliferation based on genetic traits of cells
EP3604503B1 (en) * 2017-03-28 2026-03-18 Ajinomoto Co., Inc. Additive for undifferentiation maintaining medium
CN107177542A (zh) * 2017-05-25 2017-09-19 句容亿格纳米材料厂 一种促进培养基中谷氨酰胺溶解的优化方法
ES2955861T3 (es) * 2017-05-31 2023-12-07 Promocell Gmbh Medio de cultivo para células madre pluripotentes
EP3638019A4 (en) * 2017-06-14 2020-08-26 The General Hospital Corporation VERY LOW TEMPERATURE CRYOPRESERVATION
CN107488625B (zh) * 2017-08-31 2018-12-21 广州蕊特生物科技有限公司 一种胎牛血清替代物及其制备方法和应用
CN109395095B (zh) * 2017-09-18 2021-09-24 武汉原生原代生物医药科技有限公司 体内用生物膜及其制备方法和用途
CN111278441A (zh) * 2017-10-11 2020-06-12 巴斯特生物技术 用于治疗纤维化的组合物和方法
JP7117374B2 (ja) * 2017-10-13 2022-08-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 灌流培地
WO2019081609A1 (en) * 2017-10-24 2019-05-02 Fundación Instituto De Investigación Sanitaria De Santiago De Compostela (Fidis) NANOSYSTEMS FOR CELL PROLIFERATION
KR102569522B1 (ko) * 2017-11-24 2023-08-24 주식회사 차바이오랩 세포 동결 보존용 조성물 및 이를 이용한 세포 동결 보존 방법
BR112020013238A2 (pt) * 2017-12-29 2020-12-01 Cell Cure Neurosciences Ltd. composição e método para formular células do epitélio pigmentar da retina bem como uso da dita composição para tratar uma condição retiniana
WO2019232268A1 (en) 2018-05-30 2019-12-05 Mustafa Korkut Uygun Cryopreservation of tissues and organs
CN108853489B (zh) * 2018-06-29 2019-07-02 陕西诺威利华生物科技有限公司 一种利用无血清培养基生产pedv弱毒疫苗的方法
CN108815516B (zh) * 2018-06-29 2019-03-15 陕西诺威利华生物科技有限公司 一种利用无血清培养基生产pedv灭活疫苗的方法
JPWO2020022511A1 (ja) * 2018-07-27 2021-08-02 味の素株式会社 動物細胞の浮遊培養用の添加物、浮遊培養用培地および浮遊培養方法
CN109234223B (zh) * 2018-11-21 2021-01-19 南京基蛋生物医药有限公司 低蛋白无血清细胞培养基
KR102271949B1 (ko) * 2019-04-15 2021-07-02 순천향대학교 산학협력단 포스파티딜콜린을 함유하는 선충 배양용 조성물 및 이를 이용한 선충의 배양방법
KR102132457B1 (ko) * 2019-05-10 2020-07-09 주식회사 바이오솔루션 세포외 소포를 고농도로 배양하기 위한 세포 배양배지 및 상기 세포 배양배지를 이용한 세포외 소포 고 함유 조건화 배양액의 제조방법
CN109943526B (zh) * 2019-05-23 2019-09-13 广州赛莱拉干细胞科技股份有限公司 一种促间充质干细胞增殖的无血清多肽组合物
US12297451B1 (en) 2019-10-25 2025-05-13 Regeneron Pharmaceuticals, Inc. Cell culture medium
WO2021078935A1 (en) * 2019-10-25 2021-04-29 Fundació Centre De Regulació Genòmica Culture media for mycoplasma
WO2021108806A1 (en) * 2019-11-29 2021-06-03 Rutgers, The State University Of New Jersey Compositions, kits and methods for storage of blood products and methods of use thereof
EP4065690A1 (en) 2019-11-29 2022-10-05 Rutgers, the State University of New Jersey Methods for isolating umbilical cord blood plasma products, tissue and cellular exosomes, and compositions and methods of use thereof
BR112022014275A2 (pt) * 2020-01-21 2022-09-20 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Uso de ativadores de fgf em meios de cultura
CN111849860B (zh) * 2020-06-01 2021-12-21 浙江大学 一种利用铁元素调控肠道干细胞分化的方法及应用
CN115989318A (zh) * 2020-06-05 2023-04-18 阿普賽德食品公司 用于产生免屠宰肉的营养培养基
CN111534478A (zh) * 2020-06-24 2020-08-14 肇庆大华农生物药品有限公司 用于培养mdck细胞系的培养基及其制备方法
US12575558B2 (en) * 2020-11-10 2026-03-17 Axogen Corporation Packaging system for a medical product
CN112514892B (zh) * 2020-12-25 2022-06-14 广州赛莱拉干细胞科技股份有限公司 一种外泌体冻存保护液及其制备方法
CN112501113B (zh) * 2021-02-03 2021-04-27 上海奥浦迈生物科技股份有限公司 一种hek293细胞组合梯度培养基及其用途
EP4308686A4 (en) * 2021-03-17 2025-04-09 Wilk Technologies International Ltd. Methods and compositions for the in vitro enhancement of milk production from breast epithelial cells
CN113061584A (zh) * 2021-05-14 2021-07-02 赵峻岭 一种能促进腺病毒生长的培养基添加物
US11692167B2 (en) * 2021-08-02 2023-07-04 Montana State University Chemically defined serum replacements for cell culture
US11878036B2 (en) 2022-05-25 2024-01-23 Neuvian LLC Vaginal care compositions and methods of improving vaginal health
KR20240177180A (ko) * 2023-06-19 2024-12-27 (주)엑셀세라퓨틱스 T 세포 배양용 배지 조성물
CN122206788A (zh) 2023-11-07 2026-06-12 赢创运营有限公司 细胞营养预载
WO2025199245A1 (en) * 2024-03-19 2025-09-25 Immunis, Inc. Method of making and using secretome composition
US12421441B1 (en) 2025-05-19 2025-09-23 King Fahd University Of Petroleum And Minerals Method for microbially enhanced oil recovery

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000500327A (ja) * 1995-10-19 2000-01-18 アドバンスド リプロダクション テクノロジーズ，インコーポレイテッド 生殖細胞および胚の生存および機能を改善する方法および組成物
US20060188867A1 (en) * 2005-01-28 2006-08-24 Canadian Blood Services Method of cryopreserving cells and tissues by liposomal delivery of sugars to enhance post-thaw viability
JP2007502130A (ja) * 2003-05-09 2007-02-08 ライフブラッド メディカル インコーポレーテッド 臓器および細胞の生存能力を維持するための組成物
WO2013071151A1 (en) * 2011-11-11 2013-05-16 Essential Pharmaceuticals, Llc Kit comprising serum replacement and labile factors

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721676A (en) * 1982-12-14 1988-01-26 Genencor, Inc. Novel thermophile isolate having thermostable hydrolytic activity
US4560655A (en) 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
DE3827578A1 (de) 1988-08-13 1990-02-15 Siepmann Friedrich W Verfahren und vorrichtung zur bestimmung oxidierbarer wasserinhaltsstoffe einer waessrigen probenfluessigkeit
US6048728A (en) 1988-09-23 2000-04-11 Chiron Corporation Cell culture medium for enhanced cell growth, culture longevity, and product expression
US5834312A (en) 1990-01-29 1998-11-10 Hy-Gene, Inc. Process and media for the growth of human epithelia
US5952198A (en) * 1995-05-04 1999-09-14 Bayer Corporation Production of recombinant Factor VIII in the presence of liposome-like substances of mixed composition
AU6698196A (en) 1995-08-15 1997-03-12 Universite Libre De Bruxelles Liposomes preparation method and plant
EP2221361A3 (en) 1996-08-30 2011-02-09 Life Technologies Corporation Method for producing a polypeptide in vitro in mammalian cells in a protein-free and serum-free culture medium
US6103529A (en) 1996-10-10 2000-08-15 Life Technologies, Inc. Animal cell culture media comprising peptides derived from rice
US6833271B2 (en) * 1996-12-04 2004-12-21 Medi-Cult A/S Serum-free cell culture media
US5985538A (en) 1997-08-01 1999-11-16 Saint Barnabas Medical Center Cryopreservation and cell culture medium comprising less than 50 mM sodium ions and greater than 100 mM choline salt
GB9817805D0 (en) 1998-08-14 1998-10-14 Danisco Use of a composition
EP1226233B1 (en) 1999-08-05 2011-06-29 ABT Holding Company Multipotent adult stem cells and methods for isolation
US7112576B1 (en) * 1999-12-10 2006-09-26 Regents Of The University Of Minnesota Compositions and methods for cryopreservation of peripheral blood lymphocytes
US7455983B2 (en) 2000-01-11 2008-11-25 Geron Corporation Medium for growing human embryonic stem cells
WO2003064598A2 (en) 2002-01-25 2003-08-07 Genzyme Corporation Serum-free media for chondrocytes and methods of use thereof
WO2005072523A2 (en) 2004-02-02 2005-08-11 I.M.T. Interface Multigrad Technology Ltd. Biological material and methods and solutions for preservation thereof
US8252591B2 (en) 2004-05-07 2012-08-28 Whitehead Institute For Biomedical Research Hormone responsive tissue culture system and uses thereof
US20050287666A1 (en) 2004-06-29 2005-12-29 Invitrogen Corporation Cell culture medium comprising transition metals or trace elements
AU2005271723B2 (en) 2004-07-13 2010-12-16 Asterias Biotherapeutics, Inc. Medium for growing human embryonic stem cells
WO2006045064A2 (en) 2004-10-20 2006-04-27 Whitehead Institute For Biomedical Research Cultured hematopoietic stem cells and method for expansion and analysis thereof
ES2361559T3 (es) 2004-11-02 2011-06-20 Ares Trading S.A. Medio de cultivo de células exento de suero para mamíferos.
US9101590B2 (en) 2005-07-29 2015-08-11 Yale University Defined culture conditions of human embryonic stem cells
JP5205275B2 (ja) 2005-12-21 2013-06-05 セントクローネ インターナショナル エービー 散在性ガンの治療法
EP2420565B1 (en) 2006-02-23 2017-08-30 ViaCyte, Inc. Compositions and methods useful for culturing differentiable cells
JP5080779B2 (ja) 2006-10-25 2012-11-21 テルモ株式会社 リポソーム製剤の製造方法
EP2155862A2 (en) 2007-05-04 2010-02-24 Whitehead Institute For Biomedical Research Ex vivo expansion of human hematopoietic stem cells
US20110244502A1 (en) 2007-08-10 2011-10-06 Whitehead Institute For Biomedical Research Hormone responsive tissue culture system and uses thereof
FI20096288A0 (fi) * 2009-12-04 2009-12-04 Kristiina Rajala Formulations and methods for culturing stem cells

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000500327A (ja) * 1995-10-19 2000-01-18 アドバンスド リプロダクション テクノロジーズ，インコーポレイテッド 生殖細胞および胚の生存および機能を改善する方法および組成物
JP2007502130A (ja) * 2003-05-09 2007-02-08 ライフブラッド メディカル インコーポレーテッド 臓器および細胞の生存能力を維持するための組成物
US20060188867A1 (en) * 2005-01-28 2006-08-24 Canadian Blood Services Method of cryopreserving cells and tissues by liposomal delivery of sugars to enhance post-thaw viability
WO2013071151A1 (en) * 2011-11-11 2013-05-16 Essential Pharmaceuticals, Llc Kit comprising serum replacement and labile factors

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020218584A1 (ja) * 2019-04-26 2020-10-29 味の素株式会社 細胞培養用組成物
WO2024024892A1 (ja) * 2022-07-28 2024-02-01 公立大学法人山陽小野田市立山口東京理科大学 凍結保存用の組成物、凍結保存方法、及び凍結した細胞又は生体組織

Also Published As

Publication number Publication date
US9637721B2 (en) 2017-05-02
AU2014364368A1 (en) 2016-07-07
SG11201604994UA (en) 2016-07-28
US20150175956A1 (en) 2015-06-25
CL2016001553A1 (es) 2017-03-17
CA2934487A1 (en) 2015-06-25
EP3083978A4 (en) 2017-08-30
EP3083978A1 (en) 2016-10-26
WO2015095651A1 (en) 2015-06-25
IL246262A0 (en) 2016-07-31
EA201691297A1 (ru) 2016-11-30
TW201527534A (zh) 2015-07-16
KR20160125352A (ko) 2016-10-31
AR098875A1 (es) 2016-06-22
MX2016008251A (es) 2016-10-13
BR112016014488A2 (pt) 2017-08-08
US20170198251A1 (en) 2017-07-13
CN106062205A (zh) 2016-10-26

Similar Documents

Publication Publication Date Title
US9637721B2 (en) Media for cell culture
Yang et al. Culture conditions and types
US5474931A (en) Media concentrate technology
Zhang et al. Rational development of a serum-free medium and fed-batch process for a GS-CHO cell line expressing recombinant antibody
US20050227355A1 (en) Serum-free cell culture media
MX2012014232A (es) Medio de cultivo celular definido quimicamente libre de suero.
JP6990659B2 (ja) がん幹細胞（ｃｓｃ）含有細胞集団の培養のための化学的に規定された培地
JP7492013B2 (ja) 培養培地中でのｆｇｆ活性化剤の利用
MXPA06003028A (es) Medios de cultivo de celulas.
JP2018085996A (ja) 血清代替物および不安定因子を備えるキット
US20200208120A1 (en) Riboflavin derivative-containing medium
US6833271B2 (en) Serum-free cell culture media
Mukherjee et al. Common reagents and medium for mammalian cell culture
PT99048B (pt) Processo de preparacao de um meio de cultura de celulas de mamifero, isento de soro, a base de meio basal, levedura hidrolisada, dextrano ou albumina, insulinatransferrina, frutose ferrica. citrato e sulfato ferroso e um componente de acido gordo
JP2004135672A (ja) 動物細胞又は組織を培養するための、ポリエチレングリコールを含んで成る組成物
Henschler Cell Culture Media
TW202315937A (zh) 細胞之處理方法
Master et al. T cell media: a comprehensive guide to key components
US20120264208A1 (en) Materials and methods for enhanced iron uptake in cell culture
Cohen et al. Biotin and choline replace the growth requirement of Madin‐Darby canine kidney cells for high‐density lipoproteins
Asaduzzaman et al. Culture media for animal cells
JP2800338B2 (ja) 細胞培養用無血清培地の調製方法
TW202536166A (zh) 細胞的培養方法
Mizrahi et al. Department of Biotechnology, Israel Institute for Biological Research
Collodi et al. Serum-free media

Legal Events

Date Code Title Description
A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20170418

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20171219

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20171219

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20181024

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20181030

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20190528