JP2017165987A5 - - Google Patents
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- Publication number
- JP2017165987A5 JP2017165987A5 JP2017122887A JP2017122887A JP2017165987A5 JP 2017165987 A5 JP2017165987 A5 JP 2017165987A5 JP 2017122887 A JP2017122887 A JP 2017122887A JP 2017122887 A JP2017122887 A JP 2017122887A JP 2017165987 A5 JP2017165987 A5 JP 2017165987A5
- Authority
- JP
- Japan
- Prior art keywords
- silicone hydrogel
- group
- monomer
- methyl
- meth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 229920001296 polysiloxane Polymers 0.000 claims 54
- 239000000017 hydrogel Substances 0.000 claims 53
- 239000000178 monomer Substances 0.000 claims 39
- -1 styryl compound Chemical class 0.000 claims 18
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 16
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 10
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 10
- 229920006294 polydialkylsiloxane Polymers 0.000 claims 9
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical class C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 8
- 239000003431 cross linking reagent Substances 0.000 claims 8
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 7
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 7
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims 6
- 229920002554 vinyl polymer Polymers 0.000 claims 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 4
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical group CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 4
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 4
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 4
- 239000011541 reaction mixture Substances 0.000 claims 4
- AFXKUUDFKHVAGI-UHFFFAOYSA-N 1-methyl-3-methylidenepyrrolidin-2-one Chemical compound CN1CCC(=C)C1=O AFXKUUDFKHVAGI-UHFFFAOYSA-N 0.000 claims 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 3
- 150000001408 amides Chemical class 0.000 claims 3
- UYMKPFRHYYNDTL-UHFFFAOYSA-N ethenamine Chemical group NC=C UYMKPFRHYYNDTL-UHFFFAOYSA-N 0.000 claims 3
- RQAKESSLMFZVMC-UHFFFAOYSA-N n-ethenylacetamide Chemical compound CC(=O)NC=C RQAKESSLMFZVMC-UHFFFAOYSA-N 0.000 claims 3
- 229910052710 silicon Inorganic materials 0.000 claims 3
- 239000010703 silicon Substances 0.000 claims 3
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 3
- ONMLAAZEQUPQSE-UHFFFAOYSA-N (3-hydroxy-2,2-dimethylpropyl) 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(C)(C)CO ONMLAAZEQUPQSE-UHFFFAOYSA-N 0.000 claims 2
- ZZDBHIVVDUTWJC-UHFFFAOYSA-N 1-methyl-5-methylidenepyrrolidin-2-one Chemical compound CN1C(=C)CCC1=O ZZDBHIVVDUTWJC-UHFFFAOYSA-N 0.000 claims 2
- QRIMLDXJAPZHJE-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(O)CO QRIMLDXJAPZHJE-UHFFFAOYSA-N 0.000 claims 2
- WULAHPYSGCVQHM-UHFFFAOYSA-N 2-(2-ethenoxyethoxy)ethanol Chemical compound OCCOCCOC=C WULAHPYSGCVQHM-UHFFFAOYSA-N 0.000 claims 2
- GVNVAWHJIKLAGL-UHFFFAOYSA-N 2-(cyclohexen-1-yl)cyclohexan-1-one Chemical compound O=C1CCCCC1C1=CCCCC1 GVNVAWHJIKLAGL-UHFFFAOYSA-N 0.000 claims 2
- VUIWJRYTWUGOOF-UHFFFAOYSA-N 2-ethenoxyethanol Chemical group OCCOC=C VUIWJRYTWUGOOF-UHFFFAOYSA-N 0.000 claims 2
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims 2
- VDORPYPVQAFLTR-UHFFFAOYSA-N 5-methyl-3-methylidenepyrrolidin-2-one Chemical compound CC1CC(=C)C(=O)N1 VDORPYPVQAFLTR-UHFFFAOYSA-N 0.000 claims 2
- 101150065749 Churc1 gene Proteins 0.000 claims 2
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 2
- 102100038239 Protein Churchill Human genes 0.000 claims 2
- 150000001252 acrylic acid derivatives Chemical class 0.000 claims 2
- 125000002947 alkylene group Chemical group 0.000 claims 2
- XXROGKLTLUQVRX-UHFFFAOYSA-N allyl alcohol Chemical compound OCC=C XXROGKLTLUQVRX-UHFFFAOYSA-N 0.000 claims 2
- 150000001735 carboxylic acids Chemical class 0.000 claims 2
- 150000002170 ethers Chemical class 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- PNLUGRYDUHRLOF-UHFFFAOYSA-N n-ethenyl-n-methylacetamide Chemical compound C=CN(C)C(C)=O PNLUGRYDUHRLOF-UHFFFAOYSA-N 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 125000005504 styryl group Chemical group 0.000 claims 2
- JWYVGKFDLWWQJX-UHFFFAOYSA-N 1-ethenylazepan-2-one Chemical compound C=CN1CCCCCC1=O JWYVGKFDLWWQJX-UHFFFAOYSA-N 0.000 claims 1
- CXNYYQBHNJHBNH-UHFFFAOYSA-N 1-ethyl-5-methylidenepyrrolidin-2-one Chemical compound CCN1C(=C)CCC1=O CXNYYQBHNJHBNH-UHFFFAOYSA-N 0.000 claims 1
- IEVADDDOVGMCSI-UHFFFAOYSA-N 2-hydroxybutyl 2-methylprop-2-enoate Chemical compound CCC(O)COC(=O)C(C)=C IEVADDDOVGMCSI-UHFFFAOYSA-N 0.000 claims 1
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims 1
- VHSHLMUCYSAUQU-UHFFFAOYSA-N 2-hydroxypropyl methacrylate Chemical compound CC(O)COC(=O)C(C)=C VHSHLMUCYSAUQU-UHFFFAOYSA-N 0.000 claims 1
- UJTICEIMISHYHJ-UHFFFAOYSA-N 3-(2-carboxyethenylamino)propanoic acid Chemical compound OC(=O)CCNC=CC(O)=O UJTICEIMISHYHJ-UHFFFAOYSA-N 0.000 claims 1
- QOXOZONBQWIKDA-UHFFFAOYSA-N 3-hydroxypropyl Chemical group [CH2]CCO QOXOZONBQWIKDA-UHFFFAOYSA-N 0.000 claims 1
- ACOUENYDWAONBH-UHFFFAOYSA-N 3-methylidene-1-propan-2-ylpyrrolidin-2-one Chemical compound CC(C)N1CCC(=C)C1=O ACOUENYDWAONBH-UHFFFAOYSA-N 0.000 claims 1
- XVGZUJYMDCFKIZ-UHFFFAOYSA-N 3-methylidene-1-propylpyrrolidin-2-one Chemical compound CCCN1CCC(=C)C1=O XVGZUJYMDCFKIZ-UHFFFAOYSA-N 0.000 claims 1
- SXIFAEWFOJETOA-UHFFFAOYSA-N 4-hydroxy-butyl Chemical group [CH2]CCCO SXIFAEWFOJETOA-UHFFFAOYSA-N 0.000 claims 1
- VXHPJUGRGNVHLL-UHFFFAOYSA-N 4-hydroxybut-1-enylcarbamic acid Chemical compound C(CO)C=CNC(=O)O VXHPJUGRGNVHLL-UHFFFAOYSA-N 0.000 claims 1
- XVUWMCJNMDQXKX-UHFFFAOYSA-N 5-ethyl-3-methylidenepyrrolidin-2-one Chemical compound CCC1CC(=C)C(=O)N1 XVUWMCJNMDQXKX-UHFFFAOYSA-N 0.000 claims 1
- YNQNQJPLBDEVRW-UHFFFAOYSA-N 5-methylidene-1-propan-2-ylpyrrolidin-2-one Chemical compound CC(C)N1C(=C)CCC1=O YNQNQJPLBDEVRW-UHFFFAOYSA-N 0.000 claims 1
- RRUNPGIXAGEPSW-UHFFFAOYSA-N 5-methylidene-1-propylpyrrolidin-2-one Chemical compound CCCN1C(=C)CCC1=O RRUNPGIXAGEPSW-UHFFFAOYSA-N 0.000 claims 1
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical group NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 claims 1
- NSMPFGWDOGVQDR-UHFFFAOYSA-N N-carboxy-beta-alanine Chemical compound OC(=O)CCNC(O)=O NSMPFGWDOGVQDR-UHFFFAOYSA-N 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 239000006096 absorbing agent Substances 0.000 claims 1
- 150000003926 acrylamides Chemical class 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- FXPHJTKVWZVEGA-UHFFFAOYSA-N ethenyl hydrogen carbonate Chemical class OC(=O)OC=C FXPHJTKVWZVEGA-UHFFFAOYSA-N 0.000 claims 1
- 125000001033 ether group Chemical group 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 1
- 150000002734 metacrylic acid derivatives Chemical class 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- DFMIMUDDPBAKFS-UHFFFAOYSA-N n-ethenyl-n-ethylformamide Chemical compound CCN(C=C)C=O DFMIMUDDPBAKFS-UHFFFAOYSA-N 0.000 claims 1
- HAZULKRCTMKQAS-UHFFFAOYSA-N n-ethenylbutanamide Chemical compound CCCC(=O)NC=C HAZULKRCTMKQAS-UHFFFAOYSA-N 0.000 claims 1
- ZQXSMRAEXCEDJD-UHFFFAOYSA-N n-ethenylformamide Chemical compound C=CNC=O ZQXSMRAEXCEDJD-UHFFFAOYSA-N 0.000 claims 1
- KYKIFKUTBWKKRE-UHFFFAOYSA-N n-ethenylpropan-2-amine Chemical compound CC(C)NC=C KYKIFKUTBWKKRE-UHFFFAOYSA-N 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 125000000547 substituted alkyl group Chemical group 0.000 claims 1
- LVLANIHJQRZTPY-UHFFFAOYSA-N vinyl carbamate Chemical class NC(=O)OC=C LVLANIHJQRZTPY-UHFFFAOYSA-N 0.000 claims 1
- 229920001567 vinyl ester resin Polymers 0.000 claims 1
- 0 *C(N(*)C(*)=O)=C Chemical compound *C(N(*)C(*)=O)=C 0.000 description 6
- PBGPBHYPCGDFEZ-UHFFFAOYSA-N C=CN(CCCC1)C1=O Chemical compound C=CN(CCCC1)C1=O PBGPBHYPCGDFEZ-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161579690P | 2011-12-23 | 2011-12-23 | |
| US201161579683P | 2011-12-23 | 2011-12-23 | |
| US61/579,683 | 2011-12-23 | ||
| US61/579,690 | 2011-12-23 | ||
| US13/720,239 | 2012-12-19 | ||
| US13/720,239 US9588258B2 (en) | 2011-12-23 | 2012-12-19 | Silicone hydrogels formed from zero diluent reactive mixtures |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548881A Division JP6169604B2 (ja) | 2011-12-23 | 2012-12-20 | 希釈剤を用いない反応性混合物から形成されるシリコーンヒドロゲル |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017165987A JP2017165987A (ja) | 2017-09-21 |
| JP2017165987A5 true JP2017165987A5 (cg-RX-API-DMAC7.html) | 2017-11-02 |
| JP6348209B2 JP6348209B2 (ja) | 2018-06-27 |
Family
ID=47559699
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548881A Active JP6169604B2 (ja) | 2011-12-23 | 2012-12-20 | 希釈剤を用いない反応性混合物から形成されるシリコーンヒドロゲル |
| JP2017122887A Active JP6348209B2 (ja) | 2011-12-23 | 2017-06-23 | 希釈剤を用いない反応性混合物から形成されるシリコーンヒドロゲル |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548881A Active JP6169604B2 (ja) | 2011-12-23 | 2012-12-20 | 希釈剤を用いない反応性混合物から形成されるシリコーンヒドロゲル |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9588258B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3473662A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6169604B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102048679B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104144971B (cg-RX-API-DMAC7.html) |
| AR (1) | AR089467A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112014015438A8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2859929A1 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2629932C2 (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201403467UA (cg-RX-API-DMAC7.html) |
| TW (1) | TWI582122B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013096594A1 (cg-RX-API-DMAC7.html) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9588258B2 (en) * | 2011-12-23 | 2017-03-07 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels formed from zero diluent reactive mixtures |
| US8937110B2 (en) | 2011-12-23 | 2015-01-20 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels having a structure formed via controlled reaction kinetics |
| US9156934B2 (en) | 2011-12-23 | 2015-10-13 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising n-vinyl amides and hydroxyalkyl (meth)acrylates or (meth)acrylamides |
| US9140825B2 (en) | 2011-12-23 | 2015-09-22 | Johnson & Johnson Vision Care, Inc. | Ionic silicone hydrogels |
| US8937111B2 (en) | 2011-12-23 | 2015-01-20 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising desirable water content and oxygen permeability |
| US10209534B2 (en) | 2012-03-27 | 2019-02-19 | Johnson & Johnson Vision Care, Inc. | Increased stiffness center optic in soft contact lenses for astigmatism correction |
| TWI665221B (zh) * | 2014-04-18 | 2019-07-11 | 美商班茲研發公司 | 用於隱形眼鏡及眼內透鏡之（甲基）丙烯醯胺聚合物 |
| CN105713153B (zh) * | 2014-12-05 | 2019-05-10 | 晶硕光学股份有限公司 | 阻隔紫外光的硅水胶组合物及包含其的硅水胶镜片 |
| JP6149028B2 (ja) * | 2014-12-05 | 2017-06-14 | ペガヴィジョン コーポレーションＰｅｇａｖｉｓｉｏｎ Ｃｏｒｐｏｒａｔｉｏｎ | Ｕｖ遮断性シリコーンヒドロゲル組成物、及びそれを含むシリコーンヒドロゲルコンタクトレンズ |
| US9482788B2 (en) * | 2014-12-05 | 2016-11-01 | Pegavision Corporation | UV-blocking silicone hydrogel composition and silicone hydrogel contact lens containing thereof |
| TWI571670B (zh) * | 2015-01-09 | 2017-02-21 | Composite contact lenses | |
| US10371865B2 (en) | 2016-07-06 | 2019-08-06 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising polyamides |
| BR112019000204A2 (pt) * | 2016-07-06 | 2019-04-16 | Johnson & Johnson Vision Care, Inc. | óptica central de dureza aumentada em lentes de contato macias para correção de astigmatismo |
| US11125916B2 (en) | 2016-07-06 | 2021-09-21 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels comprising N-alkyl methacrylamides and contact lenses made thereof |
| ES2678773B1 (es) * | 2017-01-16 | 2019-06-12 | Consejo Superior Investigacion | Recubrimientos tipo hidrogel en base vinil-lactamas |
| EP3622973A4 (en) * | 2017-05-10 | 2021-01-06 | Toray Industries, Inc. | Medical device |
| HUE055667T2 (hu) | 2017-06-07 | 2021-12-28 | Alcon Inc | Eljárás szilikon hidrogél kontaktlencsék elõállítására |
| KR102754373B1 (ko) | 2017-06-07 | 2025-01-15 | 알콘 인코포레이티드 | 실리콘 하이드로겔 콘택트 렌즈 |
| US10866344B2 (en) | 2017-06-07 | 2020-12-15 | Alcon Inc. | Silicone hydrogel contact lenses |
| CN113544195B (zh) * | 2019-03-14 | 2023-05-02 | 美国陶氏有机硅公司 | 具有聚(甲基)丙烯酸酯基团的聚有机硅氧烷及其制备方法和用途 |
| TWI784272B (zh) * | 2019-05-31 | 2022-11-21 | 美商羅門哈斯電子材料有限公司 | 抗蝕劑組成物、其製造方法及包含其的製品 |
| TW202434214A (zh) | 2022-12-21 | 2024-09-01 | 美商壯生和壯生視覺關懷公司 | 眼科裝置之組成物(二) |
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-
2012
- 2012-12-19 US US13/720,239 patent/US9588258B2/en active Active
- 2012-12-20 CN CN201280070500.1A patent/CN104144971B/zh active Active
- 2012-12-20 EP EP18183706.3A patent/EP3473662A1/en not_active Withdrawn
- 2012-12-20 CA CA2859929A patent/CA2859929A1/en not_active Abandoned
- 2012-12-20 KR KR1020147020570A patent/KR102048679B1/ko active Active
- 2012-12-20 BR BR112014015438A patent/BR112014015438A8/pt not_active Application Discontinuation
- 2012-12-20 WO PCT/US2012/070890 patent/WO2013096594A1/en not_active Ceased
- 2012-12-20 EP EP12815931.6A patent/EP2794724B9/en active Active
- 2012-12-20 JP JP2014548881A patent/JP6169604B2/ja active Active
- 2012-12-20 SG SG11201403467UA patent/SG11201403467UA/en unknown
- 2012-12-20 RU RU2014130241A patent/RU2629932C2/ru active
- 2012-12-22 TW TW101149232A patent/TWI582122B/zh active
- 2012-12-26 AR ARP120104985A patent/AR089467A1/es not_active Application Discontinuation
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2017
- 2017-01-25 US US15/415,061 patent/US10017596B2/en active Active
- 2017-06-23 JP JP2017122887A patent/JP6348209B2/ja active Active
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