|
EP0081756B1
(en)
|
1981-12-14 |
1985-05-15 |
MEDEA RESEARCH S.r.l. |
New compounds with antiinflammatory and antitussive activity, process for their preparation and relative pharmaceutical compositions
|
|
EP0946180A4
(en)
|
1996-10-07 |
2003-07-23 |
Smithkline Beecham Corp |
METHODS FOR STIMULATING BONE FORMATION
|
|
GB9823871D0
(en)
|
1998-10-30 |
1998-12-23 |
Pharmacia & Upjohn Spa |
2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
|
|
US6320050B1
(en)
|
1999-03-29 |
2001-11-20 |
Hoffmann-La Roche Inc. |
Heteroaromatic glucokinase activators
|
|
US6610846B1
(en)
|
1999-03-29 |
2003-08-26 |
Hoffman-La Roche Inc. |
Heteroaromatic glucokinase activators
|
|
BR0015671A
(pt)
|
1999-11-18 |
2002-07-23 |
Novartis Ag |
Compostos de aminoheterociclamida pesticidal
|
|
EP1282612B1
(en)
|
2000-05-03 |
2004-12-29 |
F. Hoffmann-La Roche Ag |
Alkynyl phenyl heteroaromatic glucokinase activators
|
|
JP4742333B2
(ja)
|
2000-11-13 |
2011-08-10 |
日本農薬株式会社 |
Ｎ−チアジアゾリルシクロプロパンカルボン酸アミド類およびこれを有効成分とする殺虫、殺ダニ剤
|
|
EP1341774B1
(en)
|
2000-12-06 |
2006-02-01 |
F. Hoffmann-La Roche Ag |
Fused heteroaromatic glucokinase activators
|
|
JPWO2003020313A1
(ja)
*
|
2001-09-04 |
2004-12-16 |
小野薬品工業株式会社 |
スフィンゴシン−１−リン酸受容体調節剤からなる呼吸器疾患治療剤
|
|
KR101018318B1
(ko)
*
|
2001-12-21 |
2011-03-04 |
노보 노르디스크 에이/에스 |
Ｇｋ 활성제로서의 아미드 유도체
|
|
TW200307539A
(en)
|
2002-02-01 |
2003-12-16 |
Bristol Myers Squibb Co |
Cycloalkyl inhibitors of potassium channel function
|
|
BR0309546A
(pt)
|
2002-04-26 |
2005-02-15 |
Hoffmann La Roche |
Composto, composição farmacêutica que compreende o mesmo, processo para a sua preparação e utilização e método para tratamento profilático ou terapêutico de diabetes do tipo ii
|
|
MY141521A
(en)
|
2002-12-12 |
2010-05-14 |
Hoffmann La Roche |
5-substituted-six-membered heteroaromatic glucokinase activators
|
|
JP4621198B2
(ja)
*
|
2003-02-11 |
2011-01-26 |
プロシディオン・リミテッド |
トリ（シクロ）置換アミドグルコキナーゼ活性化化合物
|
|
GB0329498D0
(en)
*
|
2003-12-19 |
2004-01-28 |
Novartis Ag |
Organic compounds
|
|
TWI349550B
(en)
*
|
2003-12-26 |
2011-10-01 |
|
A thiazole derivative and adenosine a2a receptor antagonist containing the same
|
|
BRPI0507278A
(pt)
|
2004-01-30 |
2007-06-26 |
Vertex Pharma |
moduladores dos transportadores do cassete de ligação ao atp
|
|
AU2005311269B2
(en)
|
2004-12-03 |
2011-11-10 |
Transtech Pharma, Inc. |
Heteroaromatic glucokinase activators
|
|
US7888374B2
(en)
*
|
2005-01-28 |
2011-02-15 |
Abbott Laboratories |
Inhibitors of c-jun N-terminal kinases
|
|
AU2006285834A1
(en)
|
2005-08-31 |
2007-03-08 |
Astellas Pharma Inc. |
Thiazole derivative
|
|
GT200600429A
(es)
|
2005-09-30 |
2007-04-30 |
|
Compuestos organicos
|
|
WO2007043568A1
(ja)
*
|
2005-10-12 |
2007-04-19 |
Toa Eiyo Ltd. |
Ｓ１ｐ３受容体拮抗剤
|
|
EP2016065B1
(en)
|
2005-12-28 |
2012-09-19 |
Vertex Pharmaceuticals Incorporated |
1-(benzo[d][1,3]dioxol-5-yl)-n-(phenyl)cyclopropane-carboxamide derivatives and related compounds as modulators of atp-binding cassette transporters for the treatment of cystic fibrosis
|
|
US7671221B2
(en)
|
2005-12-28 |
2010-03-02 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
|
EP2049518B1
(en)
|
2006-05-31 |
2011-08-31 |
Takeda San Diego, Inc. |
Indazole and isoindole derivatives as glucokinase activating agents.
|
|
US7888504B2
(en)
|
2006-07-06 |
2011-02-15 |
Bristol-Myers Squibb Company |
Glucokinase activators and methods of using same
|
|
WO2008063625A2
(en)
*
|
2006-11-20 |
2008-05-29 |
Adolor Corporation |
Pyridine compounds and methods of their use
|
|
TW200831081A
(en)
|
2006-12-25 |
2008-08-01 |
Kyorin Seiyaku Kk |
Glucokinase activator
|
|
WO2008119734A2
(en)
|
2007-03-29 |
2008-10-09 |
Novartis Ag |
Process for the manufacture of organic compounds
|
|
US8563594B2
(en)
*
|
2007-05-08 |
2013-10-22 |
Allergan, Inc. |
S1P3 receptor inhibitors for treating pain
|
|
EP2164840A2
(en)
|
2007-05-09 |
2010-03-24 |
Vertex Pharmaceuticals Incorporated |
Modulators of cftr
|
|
CA2687764A1
(en)
|
2007-05-25 |
2008-12-04 |
Vertex Pharmaceuticals Incorporated |
Ion channel modulators and methods of use
|
|
WO2009011850A2
(en)
*
|
2007-07-16 |
2009-01-22 |
Abbott Laboratories |
Novel therapeutic compounds
|
|
AU2009205070A1
(en)
|
2008-01-18 |
2009-07-23 |
Astellas Pharma Inc. |
Phenyl acetamide derivative
|
|
US8957063B2
(en)
*
|
2008-02-21 |
2015-02-17 |
Boehringer Ingelheim International Gmbh |
Amine and ether compounds which modulate the CB2 receptor
|
|
NZ616097A
(en)
|
2008-03-31 |
2015-04-24 |
Vertex Pharma |
Pyridyl derivatives as cftr modulators
|
|
JP5513492B2
(ja)
*
|
2008-05-16 |
2014-06-04 |
タケダ カリフォルニア インコーポレイテッド |
グルコキナーゼ活性剤
|
|
GEP20135793B
(en)
|
2008-09-11 |
2013-03-25 |
Pfizer |
Heteroaryls amide derivatives and their use as glucokinase activators
|
|
UA104876C2
(uk)
|
2008-11-06 |
2014-03-25 |
Вертекс Фармасьютікалз Інкорпорейтед |
Модулятори atф-зв'язувальних касетних транспортерів
|
|
WO2011008475A1
(en)
*
|
2009-06-30 |
2011-01-20 |
Allergan, Inc. |
Optionally substituted 2-(arylmethyl, aryloxy or arylthio) -n- pyridin-2 -yl-aryl acetamide or 2, 2-bis (aryl) -n-pyridin-2-yl acetamide compounds as medicaments for the treatment of eye diseases
|
|
US8168795B2
(en)
*
|
2009-08-11 |
2012-05-01 |
Allergan, Inc. |
Selective sphingosine-1-phosphate receptor antagonists
|
|
JP5735634B2
(ja)
*
|
2010-04-23 |
2015-06-17 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
スフィンゴシン−１−リン酸受容体１アゴニストとしての４−（５−イソオキサゾリルまたは５−ピラゾリル−１，２，４−オキサジアゾール−３−イル）−マンデル酸アミド化合物
|
|
EP2651930B1
(en)
*
|
2010-12-16 |
2015-10-28 |
Boehringer Ingelheim International GmbH |
Biarylamide inhibitors of leukotriene production
|
|
US9658211B2
(en)
*
|
2012-04-18 |
2017-05-23 |
Hemoshear, Llc |
In vitro model for pathological or physiologic conditions
|
|
EP2878339A1
(en)
|
2013-12-02 |
2015-06-03 |
Siena Biotech S.p.A. |
SIP3 antagonists
|