JP2016533170A5 - - Google Patents

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JP2016533170A5
JP2016533170A5 JP2016519763A JP2016519763A JP2016533170A5 JP 2016533170 A5 JP2016533170 A5 JP 2016533170A5 JP 2016519763 A JP2016519763 A JP 2016519763A JP 2016519763 A JP2016519763 A JP 2016519763A JP 2016533170 A5 JP2016533170 A5 JP 2016533170A5
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Japan
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seq
antibody
acid sequence
antibodies
amino acid
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JP2016519763A
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JP6506267B2 (ja
JP2016533170A (ja
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Priority claimed from PCT/US2014/059162 external-priority patent/WO2015051320A2/en
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JP2016519763A 2013-10-03 2014-10-03 抗ｓｏｘ１０抗体のシステムおよび方法 Active JP6506267B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361886488P 2013-10-03 2013-10-03
US61/886,488 2013-10-03
US201461941907P 2014-02-19 2014-02-19
US61/941,907 2014-02-19
PCT/US2014/059162 WO2015051320A2 (en) 2013-10-03 2014-10-03 Anti-sox10 antibody systems and methods

Publications (3)

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JP2016533170A JP2016533170A (ja) 2016-10-27
JP2016533170A5 true JP2016533170A5 (https=) 2017-11-16
JP6506267B2 JP6506267B2 (ja) 2019-04-24

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JP2016519763A Active JP6506267B2 (ja) 2013-10-03 2014-10-03 抗ｓｏｘ１０抗体のシステムおよび方法

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US (2) US9816997B2 (https=)
EP (1) EP3052522B1 (https=)
JP (1) JP6506267B2 (https=)
DK (1) DK3052522T3 (https=)
ES (1) ES2765423T3 (https=)
WO (1) WO2015051320A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852592B2 (en) 2011-05-10 2014-10-07 Biocare Medical, Llc Systems and methods for anti-PAX8 antibodies
US10316103B1 (en) 2012-03-30 2019-06-11 Biocare Medical, Llc Systems and methods for anti-Uroplakin III antibodies
EP2900265B1 (en) 2012-09-27 2018-05-30 Biocare Medical, LLC Anti-uroplakin ii antibodies systems and methods
US10429390B2 (en) 2012-12-18 2019-10-01 Biocare Medical, Llc Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer
DK2962113T3 (da) 2013-02-28 2019-07-01 Biocare Medical Llc Systemer og fremgangsmåder med anti-p40-antistoffer
US9816997B2 (en) 2013-10-03 2017-11-14 Biocare Medical, Llc Anti-SOX10 antibody systems and methods
CN105238793B (zh) * 2015-11-25 2019-04-16 中国人民解放军第三军医大学 引起内耳Mondini畸形的猪SOX10突变基因及其应用
US10969392B2 (en) * 2015-12-10 2021-04-06 Vanderbilt University Methods and systems for predicting response to immunotherapies for treatment of cancer
CN106896104A (zh) * 2017-01-05 2017-06-27 Teco诊断有限公司 一种生物样品测试盒及其检测方法
CN114720689B (zh) * 2022-04-07 2024-04-09 南京中医药大学 半夏凝集素蛋白酶联免疫Elisa试剂盒及应用
CN115724965A (zh) * 2022-07-13 2023-03-03 浙江欧赛思生物科技有限公司 一种豚鼠sox10多克隆抗体的制备方法及其应用
CN115616214B (zh) * 2022-09-20 2026-03-03 湖南中医药大学 Sox10抗体的应用、试剂盒

Family Cites Families (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4145406A (en) 1977-04-11 1979-03-20 Miles Laboratories, Inc. Specific binding - adsorbent assay method and test means
US4254082A (en) 1978-06-12 1981-03-03 Miles Laboratories, Inc. Specific binding-adsorbent assay test means
CA1247538A (en) 1982-05-21 1988-12-28 Mark C. Glassy Human-human hybridomas for solid tumors
US4687732A (en) 1983-06-10 1987-08-18 Yale University Visualization polymers and their application to diagnostic medicine
US4690890A (en) 1984-04-04 1987-09-01 Cetus Corporation Process for simultaneously detecting multiple antigens using dual sandwich immunometric assay
JPS60248618A (ja) * 1984-05-24 1985-12-09 Nippon Zoki Pharmaceut Co Ltd ジペプチドを含有する潰瘍治療剤
US4792521A (en) 1985-08-15 1988-12-20 Immunomedics, Inc. Non-enzymatic immunohistochemical staining system and reagents
US4863875A (en) 1985-08-26 1989-09-05 Gia Research Company, L.P. Dye labelled antibodies as reagents for use in immunoassay systems
GB8607101D0 (en) 1986-03-21 1986-04-30 Serono Diagnostics Ltd Immunoassay
US5089423A (en) 1987-05-06 1992-02-18 Cyberfluor Inc. Immunoassay methods and reagents and methods for producing the latter
US5620845A (en) 1988-06-06 1997-04-15 Ampcor, Inc. Immunoassay diagnostic kit
US5252487A (en) 1989-05-19 1993-10-12 Cell Analysis Systems, Inc. Method and apparatus for determining the amount of oncogene protein product in a cell sample
US5719063A (en) 1989-08-25 1998-02-17 Boehringer Mannheim Corporation Multiplex immunoassay system
US6008057A (en) 1989-08-25 1999-12-28 Roche Diagnostics Corporation Immunoassay system
EP0513332A4 (en) 1990-11-14 1993-03-17 Cargill, Incorporated Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5280108A (en) 1991-09-27 1994-01-18 United States Of America Antibodies to p40
DK0752248T3 (da) 1992-11-13 2000-11-13 Idec Pharma Corp Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig
US5482698A (en) 1993-04-22 1996-01-09 Immunomedics, Inc. Detection and therapy of lesions with biotin/avidin polymer conjugates
US5487975A (en) 1993-11-15 1996-01-30 Ventana Medical Systems, Inc. Biotin/avidin formulation
EP0742830B1 (en) 1994-02-01 2001-07-18 THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services Fusion proteins that include antibody and nonantibody portions
US5869274A (en) 1995-08-09 1999-02-09 Zymed Laboratories, Inc. Immuno-histochemical method that reduces background staining
US5891658A (en) 1996-06-27 1999-04-06 FCI--FiberChem, Inc. Single-step, solid-state competitive immunoassay
EP1283268A3 (en) 1996-08-23 2004-01-02 Ludwig Institute For Cancer Research Recombinant vascular endothelial cell growth factor D (VEGF-D)
US7196164B2 (en) 1997-07-08 2007-03-27 Human Genome Sciences, Inc. Secreted protein HHTLF25
AU9498098A (en) 1997-09-22 1999-04-12 Chiron Corporation Buffers for stabilizing antigens
US7294459B1 (en) 1997-10-15 2007-11-13 President And Fellows Of Harvard College Cell regulatory genes, encoded products, and uses related thereto
US6476206B1 (en) 1998-03-27 2002-11-05 The Johns Hopkins University p40 protein acts as an oncogene
JP3524401B2 (ja) 1998-09-16 2004-05-10 株式会社ニチレイ 酵素抗体複合体およびその製造方法
EP1178838B1 (en) 1999-05-14 2004-09-29 The Regents of the University of California Macromolecular carrier based on dextran for drug and diagnostic agent delivery
US6723506B2 (en) 2000-01-20 2004-04-20 Brigham And Women's Hospital Method of identifying PAX8-PPAR gamma-nucleic acid molecules
US20030017491A1 (en) 2000-09-14 2003-01-23 Zuo-Rong Shi Chromogenic in situ hybridization methods, kits, and compositions
DE10063179A1 (de) 2000-12-18 2002-06-20 Bayer Ag Verfahren zur spezifischen Detektion von Tumorzellen und ihren Vorstufen in Gebärmutterhalsabstrichen durch simultane Messung von mindestens zwei verschiedenen molekularen Markern
US6972181B2 (en) 2001-01-12 2005-12-06 Mount Sinai School Of Medicine Of New York University Differential diagnosis of cancer and other conditions based on expression of p63
US20030133939A1 (en) 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US20020173053A1 (en) 2001-04-27 2002-11-21 Bassam Damaj Multiple simultaneous antigen detection by immunohistochemistry
US20040076955A1 (en) 2001-07-03 2004-04-22 Eos Biotechnology, Inc. Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer
US6580056B1 (en) 2001-09-21 2003-06-17 Biocare Medical Biological specimen heating device and quality control method for immunohistochemistry heat retrieval procedures
EP1480520A4 (en) 2002-02-12 2006-02-15 Raven Biotechnologies Inc EPITHELIAL CELLS FROM THE HUMAN FOLDS BUBBLE
NZ535425A (en) 2002-03-13 2008-05-30 Biogen Idec Inc Anti-alphavbeta6 antibodies
US7850912B2 (en) 2003-05-14 2010-12-14 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
AU2004229501B2 (en) 2003-04-11 2011-08-18 Medimmune, Llc Recombinant IL-9 antibodies and uses thereof
JP2007501021A (ja) 2003-05-30 2007-01-25 アレクシオン ファーマシューティカルズ， インコーポレイテッド 遺伝子操作された定常領域を含む、抗体および融合タンパク質
JP2005122810A (ja) 2003-10-16 2005-05-12 Hitachi Ltd 光ディスク装置
JP4949038B2 (ja) 2003-12-01 2012-06-06 ダコ デンマーク アクティーゼルスカブ 免疫組織化学的検出のための方法および組成物
WO2005076005A2 (en) 2004-01-30 2005-08-18 Medizinische Universität Wien A method for classifying a tumor cell sample based upon differential expression of at least two genes
US20050186642A1 (en) 2004-02-24 2005-08-25 Biocare Medical, Inc. Immunoassay reagents and methods of use thereof
MY146381A (en) 2004-12-22 2012-08-15 Amgen Inc Compositions and methods relating relating to anti-igf-1 receptor antibodies
EP1904531B1 (en) 2005-07-08 2010-10-06 Pfizer Limited Madcam antibodies
JP4736037B2 (ja) 2005-10-26 2011-07-27 株式会社イーベック ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分
US8691224B2 (en) 2005-11-30 2014-04-08 Abbvie Inc. Anti-Aβ globulomer 5F7 antibodies
JP5164411B2 (ja) 2006-03-31 2013-03-21 キヤノン株式会社 標的物質検出方法および標的物質検出キット
CA2652703C (en) 2006-06-07 2018-08-28 Bioalliance C.V. Antibodies recognizing a carbohydrate containing epitope on cd-43 and cea expressed on cancer cells and methods using same
EP2050466B1 (en) 2006-08-14 2015-10-28 Chugai Seiyaku Kabushiki Kaisha Diagnosis and treatment of cancer using anti-desmoglein-3 antibodies
WO2008073300A2 (en) 2006-12-08 2008-06-19 Lexicon Pharmaceuticals, Inc. Monoclonal antibodies against angptl3
US20080267988A1 (en) * 2007-04-11 2008-10-30 Enteron Limited Partnership Myelin specific IgE unencumbered by corresponding blocking antibodies as a causative factor in multiple sclerosis
JP5117765B2 (ja) 2007-05-28 2013-01-16 国立大学法人 東京大学 抗ｒｏｂｏ１抗体を含むｐｅｔ用腫瘍診断剤
MY151191A (en) 2007-09-26 2014-04-30 Genentech Inc Novel antibodies
EP2328931B1 (en) * 2008-08-06 2013-08-14 Eli Lilly And Company Anti-hepcidin-25 selective antibodies and uses thereof
WO2010022736A2 (en) 2008-08-29 2010-03-04 Symphogen A/S Recombinant anti-epidermal growth factor receptor antibody compositions
AU2009290544B2 (en) 2008-09-12 2015-07-16 Oxford University Innovation Limited PD-1 specific antibodies and uses thereof
US7846762B2 (en) 2008-09-22 2010-12-07 Applied Materials, Inc. Integrated emitter formation and passivation
US9040667B2 (en) 2009-05-01 2015-05-26 Dako Denmark A/S Antibody cocktail
NZ596274A (en) 2009-05-12 2013-11-29 Pfizer Blocking anti-dkk-1 antibodies and their uses
WO2011047019A1 (en) 2009-10-13 2011-04-21 Yale University An objective, quantitative method to predict histological subtype in non-small cell lung cancer
US20120321557A1 (en) 2010-02-26 2012-12-20 Forerunner Pharma Research Co., Ltd. Anti-icam3 antibody and use thereof
EP2402370A1 (en) 2010-06-29 2012-01-04 Pierre Fabre Médicament Novel antibody for the diagnosis and/or prognosis of cancer
AU2011295715B9 (en) 2010-09-03 2017-02-23 Abbvie Stemcentrx Llc Novel modulators and methods of use
WO2012048154A1 (en) 2010-10-06 2012-04-12 Biocare Medical, Llc Methods and systems for efficient processing of biological samples
US20120154983A1 (en) 2010-10-08 2012-06-21 The Regents Of The University Of California Method of Fabrication of Carbon Nanofibers on Nickel Foam
US8852592B2 (en) 2011-05-10 2014-10-07 Biocare Medical, Llc Systems and methods for anti-PAX8 antibodies
US9156915B2 (en) 2012-04-26 2015-10-13 Thomas Jefferson University Anti-GCC antibody molecules
EP2900265B1 (en) 2012-09-27 2018-05-30 Biocare Medical, LLC Anti-uroplakin ii antibodies systems and methods
US10429390B2 (en) 2012-12-18 2019-10-01 Biocare Medical, Llc Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer
DK2962113T3 (da) 2013-02-28 2019-07-01 Biocare Medical Llc Systemer og fremgangsmåder med anti-p40-antistoffer
US9816997B2 (en) 2013-10-03 2017-11-14 Biocare Medical, Llc Anti-SOX10 antibody systems and methods

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