DK3052522T3 - Anti-sox 10 antistofsystemer og -fremgangsmåder - Google Patents

Anti-sox 10 antistofsystemer og -fremgangsmåder Download PDF

Info

Publication number
DK3052522T3
DK3052522T3 DK14850426.9T DK14850426T DK3052522T3 DK 3052522 T3 DK3052522 T3 DK 3052522T3 DK 14850426 T DK14850426 T DK 14850426T DK 3052522 T3 DK3052522 T3 DK 3052522T3
Authority
DK
Denmark
Prior art keywords
sox
procedures
antibody systems
antibody
systems
Prior art date
Application number
DK14850426.9T
Other languages
Danish (da)
English (en)
Inventor
David Tacha
Weimin Qi
Original Assignee
Biocare Medical Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocare Medical Llc filed Critical Biocare Medical Llc
Application granted granted Critical
Publication of DK3052522T3 publication Critical patent/DK3052522T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57595—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving intracellular compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053—Skin, nerves, brain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK14850426.9T 2013-10-03 2014-10-03 Anti-sox 10 antistofsystemer og -fremgangsmåder DK3052522T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361886488P 2013-10-03 2013-10-03
US201461941907P 2014-02-19 2014-02-19
PCT/US2014/059162 WO2015051320A2 (en) 2013-10-03 2014-10-03 Anti-sox10 antibody systems and methods

Publications (1)

Publication Number Publication Date
DK3052522T3 true DK3052522T3 (da) 2020-02-24

Family

ID=52779309

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14850426.9T DK3052522T3 (da) 2013-10-03 2014-10-03 Anti-sox 10 antistofsystemer og -fremgangsmåder

Country Status (6)

Country Link
US (2) US9816997B2 (https=)
EP (1) EP3052522B1 (https=)
JP (1) JP6506267B2 (https=)
DK (1) DK3052522T3 (https=)
ES (1) ES2765423T3 (https=)
WO (1) WO2015051320A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852592B2 (en) 2011-05-10 2014-10-07 Biocare Medical, Llc Systems and methods for anti-PAX8 antibodies
US10316103B1 (en) 2012-03-30 2019-06-11 Biocare Medical, Llc Systems and methods for anti-Uroplakin III antibodies
US9429577B2 (en) 2012-09-27 2016-08-30 Biocare Medical, Llc Anti-uroplakin II antibodies systems and methods
US10429390B2 (en) 2012-12-18 2019-10-01 Biocare Medical, Llc Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer
EP2962113B1 (en) 2013-02-28 2019-04-03 Biocare Medical, LLC Anti-p40 antibodies systems and methods
WO2015051320A2 (en) 2013-10-03 2015-04-09 Biocare Medical, Llc Anti-sox10 antibody systems and methods
CN105238793B (zh) * 2015-11-25 2019-04-16 中国人民解放军第三军医大学 引起内耳Mondini畸形的猪SOX10突变基因及其应用
US10969392B2 (en) * 2015-12-10 2021-04-06 Vanderbilt University Methods and systems for predicting response to immunotherapies for treatment of cancer
CN106896104A (zh) * 2017-01-05 2017-06-27 Teco诊断有限公司 一种生物样品测试盒及其检测方法
CN114720689B (zh) * 2022-04-07 2024-04-09 南京中医药大学 半夏凝集素蛋白酶联免疫Elisa试剂盒及应用
CN115724965A (zh) * 2022-07-13 2023-03-03 浙江欧赛思生物科技有限公司 一种豚鼠sox10多克隆抗体的制备方法及其应用
CN115616214B (zh) * 2022-09-20 2026-03-03 湖南中医药大学 Sox10抗体的应用、试剂盒

Family Cites Families (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4145406A (en) 1977-04-11 1979-03-20 Miles Laboratories, Inc. Specific binding - adsorbent assay method and test means
US4254082A (en) 1978-06-12 1981-03-03 Miles Laboratories, Inc. Specific binding-adsorbent assay test means
CA1247538A (en) 1982-05-21 1988-12-28 Mark C. Glassy Human-human hybridomas for solid tumors
US4687732A (en) 1983-06-10 1987-08-18 Yale University Visualization polymers and their application to diagnostic medicine
US4690890A (en) 1984-04-04 1987-09-01 Cetus Corporation Process for simultaneously detecting multiple antigens using dual sandwich immunometric assay
JPS60248618A (ja) * 1984-05-24 1985-12-09 Nippon Zoki Pharmaceut Co Ltd ジペプチドを含有する潰瘍治療剤
US4792521A (en) 1985-08-15 1988-12-20 Immunomedics, Inc. Non-enzymatic immunohistochemical staining system and reagents
US4863875A (en) 1985-08-26 1989-09-05 Gia Research Company, L.P. Dye labelled antibodies as reagents for use in immunoassay systems
GB8607101D0 (en) 1986-03-21 1986-04-30 Serono Diagnostics Ltd Immunoassay
US5089423A (en) 1987-05-06 1992-02-18 Cyberfluor Inc. Immunoassay methods and reagents and methods for producing the latter
US5620845A (en) 1988-06-06 1997-04-15 Ampcor, Inc. Immunoassay diagnostic kit
US5252487A (en) 1989-05-19 1993-10-12 Cell Analysis Systems, Inc. Method and apparatus for determining the amount of oncogene protein product in a cell sample
US5719063A (en) 1989-08-25 1998-02-17 Boehringer Mannheim Corporation Multiplex immunoassay system
US6008057A (en) 1989-08-25 1999-12-28 Roche Diagnostics Corporation Immunoassay system
US5492821A (en) 1990-11-14 1996-02-20 Cargill, Inc. Stabilized polyacrylic saccharide protein conjugates
ES2136092T3 (es) 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
US5280108A (en) 1991-09-27 1994-01-18 United States Of America Antibodies to p40
MD1367C2 (ro) 1992-11-13 2000-11-30 Idec Pharmaceuticals Corporation Metode de tratament al limfomului celulelor B, anticorpi anti-CD20, hibridom.
US5482698A (en) 1993-04-22 1996-01-09 Immunomedics, Inc. Detection and therapy of lesions with biotin/avidin polymer conjugates
US5487975A (en) 1993-11-15 1996-01-30 Ventana Medical Systems, Inc. Biotin/avidin formulation
CA2182498A1 (en) 1994-02-01 1995-08-10 William J. Larochelle Fusion proteins that include antibody and nonantibody portions
US5869274A (en) 1995-08-09 1999-02-09 Zymed Laboratories, Inc. Immuno-histochemical method that reduces background staining
US5891658A (en) 1996-06-27 1999-04-06 FCI--FiberChem, Inc. Single-step, solid-state competitive immunoassay
WO1998007832A1 (en) 1996-08-23 1998-02-26 Ludwig Institute For Cancer Research Recombinant vascular endothelial cell growth factor d (vegf-d)
US7196164B2 (en) 1997-07-08 2007-03-27 Human Genome Sciences, Inc. Secreted protein HHTLF25
ATE417275T1 (de) 1997-09-22 2008-12-15 Novartis Vaccines & Diagnostic Puffern zur stabilizierung von hcv antigenen
US7294459B1 (en) 1997-10-15 2007-11-13 President And Fellows Of Harvard College Cell regulatory genes, encoded products, and uses related thereto
AU3208699A (en) 1998-03-27 1999-10-18 Johns Hopkins University, The P40 protein acts as an oncogene
JP3524401B2 (ja) 1998-09-16 2004-05-10 株式会社ニチレイ 酵素抗体複合体およびその製造方法
ES2228536T3 (es) 1999-05-14 2005-04-16 The Regents Of The University Of California Soporte macromolecular a base de dextrano para un farmaco y suministro de un agente de diagnosotico.
US6723506B2 (en) 2000-01-20 2004-04-20 Brigham And Women's Hospital Method of identifying PAX8-PPAR gamma-nucleic acid molecules
US20030017491A1 (en) 2000-09-14 2003-01-23 Zuo-Rong Shi Chromogenic in situ hybridization methods, kits, and compositions
DE10063179A1 (de) 2000-12-18 2002-06-20 Bayer Ag Verfahren zur spezifischen Detektion von Tumorzellen und ihren Vorstufen in Gebärmutterhalsabstrichen durch simultane Messung von mindestens zwei verschiedenen molekularen Markern
US6972181B2 (en) 2001-01-12 2005-12-06 Mount Sinai School Of Medicine Of New York University Differential diagnosis of cancer and other conditions based on expression of p63
US20030133939A1 (en) 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US20020173053A1 (en) 2001-04-27 2002-11-21 Bassam Damaj Multiple simultaneous antigen detection by immunohistochemistry
US20040076955A1 (en) 2001-07-03 2004-04-22 Eos Biotechnology, Inc. Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer
US6580056B1 (en) 2001-09-21 2003-06-17 Biocare Medical Biological specimen heating device and quality control method for immunohistochemistry heat retrieval procedures
CA2475356A1 (en) 2002-02-12 2003-08-21 Raven Biotechnologies, Inc. Human fetal bladder-derived epithelial cells
CN1646160A (zh) 2002-03-13 2005-07-27 拜奥根Idec马萨诸塞公司 抗αvβ6抗体
US7850912B2 (en) 2003-05-14 2010-12-14 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
JP4764818B2 (ja) 2003-04-11 2011-09-07 メディミューン，エルエルシー 組換えｉｌ−９抗体およびその使用
JP2007501021A (ja) 2003-05-30 2007-01-25 アレクシオン ファーマシューティカルズ， インコーポレイテッド 遺伝子操作された定常領域を含む、抗体および融合タンパク質
JP2005122810A (ja) 2003-10-16 2005-05-12 Hitachi Ltd 光ディスク装置
JP4949038B2 (ja) 2003-12-01 2012-06-06 ダコ デンマーク アクティーゼルスカブ 免疫組織化学的検出のための方法および組成物
WO2005076005A2 (en) 2004-01-30 2005-08-18 Medizinische Universität Wien A method for classifying a tumor cell sample based upon differential expression of at least two genes
US20050186642A1 (en) 2004-02-24 2005-08-25 Biocare Medical, Inc. Immunoassay reagents and methods of use thereof
MY146381A (en) 2004-12-22 2012-08-15 Amgen Inc Compositions and methods relating relating to anti-igf-1 receptor antibodies
EP1904531B1 (en) 2005-07-08 2010-10-06 Pfizer Limited Madcam antibodies
JP4736037B2 (ja) 2005-10-26 2011-07-27 株式会社イーベック ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分
PL2289909T3 (pl) 2005-11-30 2015-04-30 Abbvie Inc Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał
US7932100B2 (en) 2006-03-31 2011-04-26 Canon Kabushiki Kaisha Method for detecting target substance and target-substance detection kit
KR101496433B1 (ko) 2006-06-07 2015-02-26 바이오얼라이언스 씨.브이. 암세포 상에서 발현되는 ｃｄ-43 및 ｃｅａ 상의 에피토프를 함유하는 탄수화물을 인식하는 항체 및 이를 이용하는 방법
AU2007285217B2 (en) 2006-08-14 2013-02-07 Forerunner Pharma Research Co., Ltd Diagnosis and treatment of cancer using anti-desmoglein-3 antibodies
PL2121751T3 (pl) 2006-12-08 2017-07-31 Lexicon Pharmaceuticals, Inc. Przeciwciała monoklonalne przeciwko ANGPTL3
WO2008127642A1 (en) * 2007-04-11 2008-10-23 Enteron Limited Partnership Myelin specific ige unencumbered by corresponding blocking antibodies as a causative factor in multiple sclerosis
JP5117765B2 (ja) 2007-05-28 2013-01-16 国立大学法人 東京大学 抗ｒｏｂｏ１抗体を含むｐｅｔ用腫瘍診断剤
CL2008002856A1 (es) 2007-09-26 2009-01-16 Genentech Inc Anticuerpo novedoso (anticuerpo anti-integrina a5b1; mol}ecula de ácido nucleico que lo codifica; vector y célula huesped; método de producción; composición farmacéutica que lo comprende; su uso para inhibir la angiogénesis y/o permeabilidad vascular y cáncer entre otras patologías; y método de detección de la integrina a5b1).
EA201170312A1 (ru) * 2008-08-06 2012-03-30 Эли Лилли Энд Компани Селективные антитела к гепцидину-25 и их применение
US8663640B2 (en) 2008-08-29 2014-03-04 Symphogen A/S Methods using recombinant anti-epidermal growth factor receptor antibody compositions
US8927697B2 (en) 2008-09-12 2015-01-06 Isis Innovation Limited PD-1 specific antibodies and uses thereof
US7846762B2 (en) 2008-09-22 2010-12-07 Applied Materials, Inc. Integrated emitter formation and passivation
EP2425253B1 (en) 2009-05-01 2017-03-22 Dako Denmark A/S New antibody cocktail
PE20120475A1 (es) 2009-05-12 2012-05-05 Pfizer Anticuerpos especificos para dkk-1
US20120245051A1 (en) 2009-10-13 2012-09-27 Rimm David L Objective, quantitative method to predict histological subtype in non-small cell lung cancer
EP2540827A4 (en) 2010-02-26 2013-09-04 Chugai Pharmaceutical Co Ltd ANTI-ICAM3 ANTIBODY AND ITS USE
EP2402370A1 (en) 2010-06-29 2012-01-04 Pierre Fabre Médicament Novel antibody for the diagnosis and/or prognosis of cancer
CA2810016A1 (en) 2010-09-03 2012-03-08 Stem Centrx, Inc. Novel modulators and methods of use
WO2012048154A1 (en) 2010-10-06 2012-04-12 Biocare Medical, Llc Methods and systems for efficient processing of biological samples
US20120154983A1 (en) 2010-10-08 2012-06-21 The Regents Of The University Of California Method of Fabrication of Carbon Nanofibers on Nickel Foam
US8852592B2 (en) 2011-05-10 2014-10-07 Biocare Medical, Llc Systems and methods for anti-PAX8 antibodies
US9156915B2 (en) 2012-04-26 2015-10-13 Thomas Jefferson University Anti-GCC antibody molecules
US9429577B2 (en) 2012-09-27 2016-08-30 Biocare Medical, Llc Anti-uroplakin II antibodies systems and methods
US10429390B2 (en) 2012-12-18 2019-10-01 Biocare Medical, Llc Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer
EP2962113B1 (en) 2013-02-28 2019-04-03 Biocare Medical, LLC Anti-p40 antibodies systems and methods
WO2015051320A2 (en) 2013-10-03 2015-04-09 Biocare Medical, Llc Anti-sox10 antibody systems and methods

Also Published As

Publication number Publication date
WO2015051320A3 (en) 2015-06-18
US20160216269A1 (en) 2016-07-28
EP3052522A4 (en) 2017-04-12
JP6506267B2 (ja) 2019-04-24
EP3052522B1 (en) 2019-12-11
EP3052522A2 (en) 2016-08-10
ES2765423T3 (es) 2020-06-09
US20180074065A1 (en) 2018-03-15
JP2016533170A (ja) 2016-10-27
US9816997B2 (en) 2017-11-14
US10295542B2 (en) 2019-05-21
WO2015051320A2 (en) 2015-04-09

Similar Documents

Publication Publication Date Title
IL290972A (en) Anti-vista antibodies and fragments
IL271578B (en) Vaporization device systems and methods
IL261743B (en) and their uses 33–il antibodies against
IL261547B (en) Antibodies against pesidine and their uses
IL245040A0 (en) Antibodies against pdgfr-beta and their uses
PL3010841T3 (pl) Systemy i sposoby przetwarzania zamówień
IL243974A0 (en) Antibodies against -prlr and uses
DK3089994T3 (da) Fabs-in-tandem-immunglobulin og anvendelser deraf
PL3804863T5 (pl) Sposób aplikacji i system aplikacji
HRP20181580T1 (hr) Pripravci cftr irnk i povezani postupci i upotrebe
PL3060275T3 (pl) Wstrzykiwacz i sposób montażu
SG10201708143QA (en) Anti-c10orf54 antibodies and uses thereof
DK3052522T3 (da) Anti-sox 10 antistofsystemer og -fremgangsmåder
FR3005989B1 (fr) Turbopropulseur d'aeronef
EP2981840C0 (en) RADAR SYSTEMS AND METHODS
PL2784311T3 (pl) Urządzenie siłownika
UA27219S (uk) Форматор-вулканізатор 75" та 88"
TH1401006962A (th) แอนติ-ทรานสกลูตามิเนส 2 แอนติบอดี
UA27047S (uk) Редуктор до форматора-вулканізатора 75'' та 88''
TH1501000260A (th) วิธีการและระบบการพิสูจน์ตัวจริง