JP2016529055A5 - - Google Patents
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- Publication number
- JP2016529055A5 JP2016529055A5 JP2016539623A JP2016539623A JP2016529055A5 JP 2016529055 A5 JP2016529055 A5 JP 2016529055A5 JP 2016539623 A JP2016539623 A JP 2016539623A JP 2016539623 A JP2016539623 A JP 2016539623A JP 2016529055 A5 JP2016529055 A5 JP 2016529055A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrogel
- group
- radiopaque
- diol
- microspheres
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020031653A JP7483406B2 (ja) | 2013-09-06 | 2020-02-27 | ヒドロゲルポリマーのマイクロスフェア、それを含んだ組成物、および、ポリマーのマイクロスフェア |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1315936.3A GB2519738A (en) | 2013-09-06 | 2013-09-06 | Radiopaque polymers |
| GB1315936.3 | 2013-09-06 | ||
| PCT/GB2014/000351 WO2015033092A1 (en) | 2013-09-06 | 2014-09-05 | Imageable polymers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020031653A Division JP7483406B2 (ja) | 2013-09-06 | 2020-02-27 | ヒドロゲルポリマーのマイクロスフェア、それを含んだ組成物、および、ポリマーのマイクロスフェア |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016529055A JP2016529055A (ja) | 2016-09-23 |
| JP2016529055A5 true JP2016529055A5 (https=) | 2017-10-12 |
| JP6678319B2 JP6678319B2 (ja) | 2020-04-08 |
Family
ID=49486871
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016539623A Active JP6678319B2 (ja) | 2013-09-06 | 2014-09-05 | 撮像可能なポリマー |
| JP2020031653A Active JP7483406B2 (ja) | 2013-09-06 | 2020-02-27 | ヒドロゲルポリマーのマイクロスフェア、それを含んだ組成物、および、ポリマーのマイクロスフェア |
| JP2022146757A Active JP7705834B2 (ja) | 2013-09-06 | 2022-09-15 | ヒドロゲルおよびヒドロゲルを含む組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020031653A Active JP7483406B2 (ja) | 2013-09-06 | 2020-02-27 | ヒドロゲルポリマーのマイクロスフェア、それを含んだ組成物、および、ポリマーのマイクロスフェア |
| JP2022146757A Active JP7705834B2 (ja) | 2013-09-06 | 2022-09-15 | ヒドロゲルおよびヒドロゲルを含む組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US9895452B2 (https=) |
| EP (2) | EP4000639A1 (https=) |
| JP (3) | JP6678319B2 (https=) |
| CN (2) | CN111518285B (https=) |
| CA (1) | CA2922961C (https=) |
| GB (2) | GB2519738A (https=) |
| WO (1) | WO2015033092A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2519738A (en) * | 2013-09-06 | 2015-05-06 | Biocompatibles Uk Ltd | Radiopaque polymers |
| GB2521997A (en) | 2013-09-06 | 2015-07-15 | Biocompatibles Uk Ltd | Radiopaque polymers |
| US9594070B2 (en) * | 2013-11-05 | 2017-03-14 | Spectrum Tracer Services, Llc | Method using halogenated benzoic acid esters and aldehydes for hydraulic fracturing and for tracing petroleum production |
| US10265423B2 (en) | 2015-01-12 | 2019-04-23 | Biosphere Medical, Inc. | Radiopaque monomers, polymers, microspheres, and methods related thereto |
| US20190070332A1 (en) * | 2016-03-14 | 2019-03-07 | Biocompatibles Uk Limited | Oily compositions |
| US10017684B2 (en) | 2016-04-20 | 2018-07-10 | Spectrum Tracer Services, Llc | Method and compositions for hydraulic fracturing and for tracing formation water |
| EP3541368B1 (en) | 2016-11-16 | 2023-07-12 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Imageable particles, methods of making and methods of use thereof |
| CN106822983B (zh) * | 2016-12-29 | 2020-09-15 | 苏州恒瑞迦俐生生物医药科技有限公司 | 一种用于微创介入疗法治疗肿瘤疾病的可显影栓塞微球及其制备方法 |
| CN107050501B (zh) * | 2016-12-29 | 2020-09-15 | 苏州恒瑞迦俐生生物医药科技有限公司 | 一种可视化多羟基聚合体栓塞微球及其制备方法 |
| CN107854720B (zh) * | 2017-12-28 | 2020-12-08 | 苏州恒瑞迦俐生生物医药科技有限公司 | 具有造影功能的可载药多羟基聚合物栓塞微球及其制备方法 |
| EP3765096A1 (en) * | 2018-03-12 | 2021-01-20 | Boston Scientific Scimed Inc. | Scavenging methods, and scavenging system for radiocontrast agents |
| GB201810788D0 (en) | 2018-06-29 | 2018-08-15 | Biocompatibles Uk Ltd | Biodegradable polymer |
| GB201810784D0 (en) * | 2018-06-29 | 2018-08-15 | Biocompatibles Uk Ltd | Radiopaque polymers |
| JP7322073B2 (ja) | 2018-06-29 | 2023-08-07 | バイオコンパティブルズ ユーケー リミテッド | 放射線不透過性ポリマー |
| WO2020061207A1 (en) * | 2018-09-20 | 2020-03-26 | Reva Medical, Inc. | Porous bioresorbable radiopaque embolic microspheres for drug delivery |
| WO2020185897A1 (en) | 2019-03-11 | 2020-09-17 | Biocompatibles Uk Limited | Radioactive microshperes for the treatment of cns tumours |
| AU2020244771B2 (en) | 2019-03-22 | 2022-10-27 | Biocompatibles Uk Limited | Embolic microspheres and methods |
| CN111821503B (zh) * | 2019-04-17 | 2022-07-12 | 苏州恒瑞宏远医疗科技有限公司 | 一种不透射线的高效载药栓塞微球及其制备和应用 |
| WO2020247151A1 (en) | 2019-06-05 | 2020-12-10 | Boston Scientific Scimed, Inc. | Click chemistry capturable platinum-based antineoplastic agents |
| GB201910286D0 (en) | 2019-07-18 | 2019-09-04 | Biocompatibles Uk Ltd | Radiopaque polymers |
| KR20220079600A (ko) | 2019-10-07 | 2022-06-13 | 게르브 | 비분해성 방사선 불투과성 색전술 미소구체 |
| CN115279427A (zh) * | 2020-03-17 | 2022-11-01 | 微仙美国有限公司 | 液体栓子 |
| CN114099442B (zh) * | 2020-08-25 | 2024-01-30 | 复旦大学 | 用于肿瘤放化疗栓塞治疗和影像的多功能微球制剂及其制备方法 |
| US20220242817A1 (en) | 2021-01-12 | 2022-08-04 | Boston Scientific Scimed Inc. | Iodinated compounds having radiocontrast properties |
| CN113350298A (zh) * | 2021-06-11 | 2021-09-07 | 复旦大学附属中山医院 | 一种载药微球的配制方法 |
| US20230201122A1 (en) * | 2021-12-23 | 2023-06-29 | Boston Scientific Medical Device Limited | Chemoembolic compositions and methods of treatment using them |
| CN114262279B (zh) * | 2021-12-30 | 2022-12-16 | 上海汇禾医疗科技有限公司 | 一种x射线可显影分子、栓塞微球及其制备方法 |
| CN114146190B (zh) * | 2021-12-30 | 2024-01-26 | 科睿驰(深圳)医疗科技发展有限公司 | 一种高悬浮性显影微球及其制备方法 |
| US20230346535A1 (en) * | 2022-05-02 | 2023-11-02 | EmStop, Inc. | Method of Evaluating an Embolic Filter |
| EP4563569A1 (en) | 2022-08-25 | 2025-06-04 | Cardiolink Science (Shenzhen) Medical Technology Development Co., Ltd. | Amide compound containing iodo aryl or iodo heteroaryl, and preparation method therefor and use thereof |
| CN116256442A (zh) * | 2022-09-26 | 2023-06-13 | 科睿驰(深圳)医疗科技发展有限公司 | 一种聚乙烯醇栓塞微球中含碘化合物的检测方法 |
| KR102891713B1 (ko) * | 2023-11-15 | 2025-11-26 | 건국대학교 산학협력단 | 팽윤율이 증가된 하이드로젤 |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2860986A (en) | 1956-08-31 | 1958-11-18 | Eastman Kodak Co | Partially acetalized polyvinyl alcohol containing active halogen |
| US3631225A (en) | 1970-04-28 | 1971-12-28 | Union Carbide Corp | Preparation of polyvinyl acetals |
| US3840482A (en) | 1971-09-13 | 1974-10-08 | Ici Australia Ltd | Process for curing poly(vinyl alcohol)matrix beads |
| US4406878A (en) | 1978-08-02 | 1983-09-27 | Eastman Kodak Company | Iodinated contrast agent for radiography |
| US4306031A (en) | 1979-08-14 | 1981-12-15 | Mitsubishi Chemical Industries Limited | Weakly acidic cation exchange resin and process for producing same |
| EP0391741B1 (en) * | 1989-04-06 | 1995-04-19 | Merocel Corporation | Polymeric broad-spectrum antimicrobial materials |
| US5082909A (en) | 1990-10-12 | 1992-01-21 | Hercules Incorporated | Pure tungsten oxyphenolate complexes as DCPD polymerization catalysts |
| DK0586524T3 (https=) | 1991-06-03 | 1997-05-20 | Nycomed Imaging As | |
| JPH0656676A (ja) | 1992-08-05 | 1994-03-01 | Hori Shinichi | 血管塞栓用懸濁液 |
| US5330739A (en) | 1992-12-04 | 1994-07-19 | Sterling Winthrop Inc. | Iodinated benzoyl acetals and ketals for x-ray imaging |
| TW272976B (https=) * | 1993-08-06 | 1996-03-21 | Ciba Geigy Ag | |
| AU4438696A (en) * | 1995-02-03 | 1996-08-21 | Novartis Ag | Crosslinked polymers |
| AU6378096A (en) * | 1995-06-07 | 1996-12-30 | Brown University Research Foundation | Spray dried polymeric microparticles containing imaging agen ts |
| FR2784580B1 (fr) * | 1998-10-16 | 2004-06-25 | Biosepra Inc | Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci |
| US6255033B1 (en) | 1999-07-30 | 2001-07-03 | Creo, Ltd. | Positive acting photoresist compositions and imageable element |
| AU4566001A (en) * | 2000-03-13 | 2001-09-24 | Biocure Inc | Embolic compositions |
| EP1263801B1 (en) * | 2000-03-13 | 2006-05-24 | BioCure, Inc. | Tissue bulking and coating compositions |
| US6652883B2 (en) * | 2000-03-13 | 2003-11-25 | Biocure, Inc. | Tissue bulking and coating compositions |
| US6911219B2 (en) * | 2001-09-27 | 2005-06-28 | Surgica Corporation | Partially acetalized polyvinyl alcohol embolization particles, compositions containing those particles and methods of making and using them |
| EP1490120B1 (en) | 2002-03-29 | 2009-11-11 | Boston Scientific Limited | Embolization |
| CN103393605B (zh) | 2003-02-12 | 2018-05-29 | 生物相容英国有限公司 | 用于实体瘤的化学栓塞治疗的组合物 |
| US20040161466A1 (en) | 2003-02-14 | 2004-08-19 | Biocompatibles Uk Limited | Chemoembolisation |
| US7201918B2 (en) | 2004-11-16 | 2007-04-10 | Microvention, Inc. | Compositions, systems and methods for treatment of defects in blood vessels |
| KR101429774B1 (ko) | 2005-05-09 | 2014-10-02 | 바이오스피어 메디칼 에스.에이. | 마이크로스피어 및 비이온성 조영제를 사용하는 조성물 및방법 |
| EP1810698A1 (en) * | 2006-01-24 | 2007-07-25 | Biocompatibles UK Limited | Process for producing radiopaque embolic microspheres |
| CA2648243C (en) | 2006-04-11 | 2015-12-22 | Shaker A. Mousa | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof |
| US9107833B2 (en) | 2006-06-22 | 2015-08-18 | Biocompatibles Uk Limited | Rehydratable pharmaceutical product |
| WO2008039827A2 (en) * | 2006-09-26 | 2008-04-03 | Aeris Therapeutics, Inc. | Polymer systems for lung volume reduction therapy |
| JP2010526914A (ja) | 2007-05-11 | 2010-08-05 | エアリス セラピューティクス エルエルシー | 架橋した非天然ポリマーを用いる肺容量減少療法 |
| EP1992371A1 (de) | 2007-05-15 | 2008-11-19 | Occlutech GmbH | Bioresorbierbare röntgenopake Polymermaterialien und daraus hergestellte Occlussionsinstrumente |
| JP2010534563A (ja) | 2007-07-24 | 2010-11-11 | ネクスバイオ,インク. | マイクロ粒子の作製のための技術 |
| WO2009018280A2 (en) * | 2007-07-30 | 2009-02-05 | Auspex Pharamaceuticals, Inc. | Substituted indoles |
| EP2090592A1 (en) | 2007-07-31 | 2009-08-19 | OctoPlus Sciences B.V. | Biodegradable hydrogels based on click chemistry |
| CN101125225A (zh) * | 2007-08-10 | 2008-02-20 | 苏州迦俐生生物医药科技有限公司 | 微球型栓塞剂及其制备工艺 |
| CN101810587B (zh) * | 2007-08-10 | 2012-05-23 | 苏州迦俐生生物医药科技有限公司 | 微球型栓塞剂的制备工艺 |
| WO2009086098A1 (en) | 2007-12-28 | 2009-07-09 | Boston Scientific Scimed, Inc. | Porous microparticles for injection and processes for forming the same |
| US20090269390A1 (en) | 2008-04-25 | 2009-10-29 | Medtronic, Inc. | Medical devices, polymers, compositions, and methods for delivering a haloacetate |
| WO2009134344A1 (en) | 2008-04-28 | 2009-11-05 | Surmodics, Inc. | POLY-α(1→4)GLUCOPYRANOSE-BASED MATRICES WITH HYDRAZIDE CROSSLINKING |
| EP2365009A1 (en) * | 2010-03-10 | 2011-09-14 | Universite Claude Bernard Lyon 1 (UCBL) | Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof |
| ES2368307B1 (es) | 2010-04-28 | 2012-10-17 | Universidade De Santiago De Compostela | Hidrogeles elaborados a base de polímeros aniónicos de origen natural. |
| US9724421B2 (en) * | 2010-11-29 | 2017-08-08 | Centre Hospitalier Universitaire Vaudois | Chemoembolization composition comprising anti-angiogenic agents |
| CN103249436B (zh) | 2010-12-09 | 2015-09-30 | 东丽株式会社 | 生物降解性颗粒、血管栓塞材料及生物降解性颗粒的制造方法 |
| GB201101429D0 (en) | 2011-01-27 | 2011-03-16 | Biocompatibles Uk Ltd | Drug delivery system |
| HK1220119A1 (zh) * | 2013-03-15 | 2017-04-28 | Matthew R. Dreher | 可成像栓塞微球 |
| US9910037B2 (en) | 2013-03-15 | 2018-03-06 | Iris International, Inc. | Conjugation of multiple vancomycin molecules on a polyvinyl alcohol backbone for the capture of microorganisms |
| GB2521997A (en) * | 2013-09-06 | 2015-07-15 | Biocompatibles Uk Ltd | Radiopaque polymers |
| GB2519738A (en) | 2013-09-06 | 2015-05-06 | Biocompatibles Uk Ltd | Radiopaque polymers |
-
2013
- 2013-09-06 GB GB1315936.3A patent/GB2519738A/en not_active Withdrawn
-
2014
- 2014-09-05 GB GB1415730.9A patent/GB2523863B8/en active Active
- 2014-09-05 JP JP2016539623A patent/JP6678319B2/ja active Active
- 2014-09-05 EP EP21203058.9A patent/EP4000639A1/en active Pending
- 2014-09-05 EP EP14783895.7A patent/EP3041516B1/en active Active
- 2014-09-05 CN CN202010385369.4A patent/CN111518285B/zh active Active
- 2014-09-05 US US14/478,213 patent/US9895452B2/en active Active
- 2014-09-05 WO PCT/GB2014/000351 patent/WO2015033092A1/en not_active Ceased
- 2014-09-05 CA CA2922961A patent/CA2922961C/en active Active
- 2014-09-05 US US14/916,472 patent/US10098972B2/en active Active
- 2014-09-05 CN CN201480049219.9A patent/CN105517582B/zh active Active
-
2018
- 2018-09-05 US US16/122,317 patent/US10556022B2/en active Active
-
2020
- 2020-01-03 US US16/733,405 patent/US10925979B2/en active Active
- 2020-02-27 JP JP2020031653A patent/JP7483406B2/ja active Active
-
2021
- 2021-01-15 US US17/150,310 patent/US20210236660A1/en not_active Abandoned
-
2022
- 2022-09-15 JP JP2022146757A patent/JP7705834B2/ja active Active
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