JP2016528202A5 - - Google Patents
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- Publication number
- JP2016528202A5 JP2016528202A5 JP2016524930A JP2016524930A JP2016528202A5 JP 2016528202 A5 JP2016528202 A5 JP 2016528202A5 JP 2016524930 A JP2016524930 A JP 2016524930A JP 2016524930 A JP2016524930 A JP 2016524930A JP 2016528202 A5 JP2016528202 A5 JP 2016528202A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament according
- administered
- vegf antagonist
- disorder
- child
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 26
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 17
- 239000005557 antagonist Substances 0.000 claims 14
- 208000035475 disorder Diseases 0.000 claims 14
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 13
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 13
- 230000035699 permeability Effects 0.000 claims 5
- 230000002207 retinal effect Effects 0.000 claims 5
- 230000000977 initiatory effect Effects 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 3
- 238000002428 photodynamic therapy Methods 0.000 claims 3
- 208000004644 retinal vein occlusion Diseases 0.000 claims 3
- 208000037663 Best vitelliform macular dystrophy Diseases 0.000 claims 2
- 206010012689 Diabetic retinopathy Diseases 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 208000032578 Inherited retinal disease Diseases 0.000 claims 2
- 208000001344 Macular Edema Diseases 0.000 claims 2
- 206010025415 Macular oedema Diseases 0.000 claims 2
- 208000032430 Retinal dystrophy Diseases 0.000 claims 2
- 201000005667 central retinal vein occlusion Diseases 0.000 claims 2
- 201000006321 fundus dystrophy Diseases 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 208000017532 inherited retinal dystrophy Diseases 0.000 claims 2
- 201000010230 macular retinal edema Diseases 0.000 claims 2
- 230000001613 neoplastic effect Effects 0.000 claims 2
- 201000007914 proliferative diabetic retinopathy Diseases 0.000 claims 2
- 229960003876 ranibizumab Drugs 0.000 claims 2
- 201000007790 vitelliform macular dystrophy Diseases 0.000 claims 2
- 208000020938 vitelliform macular dystrophy 2 Diseases 0.000 claims 2
- 102000008102 Ankyrins Human genes 0.000 claims 1
- 108010049777 Ankyrins Proteins 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 102000014914 Carrier Proteins Human genes 0.000 claims 1
- 208000016623 Choroid neoplasm Diseases 0.000 claims 1
- 208000005590 Choroidal Neovascularization Diseases 0.000 claims 1
- 206010060823 Choroidal neovascularisation Diseases 0.000 claims 1
- 208000021089 Coats disease Diseases 0.000 claims 1
- 208000019878 Eales disease Diseases 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 201000002287 Keratoconus Diseases 0.000 claims 1
- 241000244206 Nematoda Species 0.000 claims 1
- 206010029113 Neovascularisation Diseases 0.000 claims 1
- 208000016113 North Carolina macular dystrophy Diseases 0.000 claims 1
- 206010069385 Ocular ischaemic syndrome Diseases 0.000 claims 1
- 206010030924 Optic ischaemic neuropathy Diseases 0.000 claims 1
- 208000008709 Retinal Telangiectasis Diseases 0.000 claims 1
- 208000017442 Retinal disease Diseases 0.000 claims 1
- 208000007014 Retinitis pigmentosa Diseases 0.000 claims 1
- 206010038923 Retinopathy Diseases 0.000 claims 1
- 206010038935 Retinopathy sickle cell Diseases 0.000 claims 1
- 208000027073 Stargardt disease Diseases 0.000 claims 1
- 206010044269 Toxocariasis Diseases 0.000 claims 1
- 206010046851 Uveitis Diseases 0.000 claims 1
- 102000009524 Vascular Endothelial Growth Factor A Human genes 0.000 claims 1
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 claims 1
- 206010047115 Vasculitis Diseases 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 108091008324 binding proteins Proteins 0.000 claims 1
- 210000001775 bruch membrane Anatomy 0.000 claims 1
- 201000002588 choroid cancer Diseases 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000009266 disease activity Effects 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 239000012678 infectious agent Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002458 infectious effect Effects 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 201000001119 neuropathy Diseases 0.000 claims 1
- 230000007823 neuropathy Effects 0.000 claims 1
- 230000000414 obstructive effect Effects 0.000 claims 1
- 244000052769 pathogen Species 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- 208000033808 peripheral neuropathy Diseases 0.000 claims 1
- 230000000649 photocoagulation Effects 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
- 108091008601 sVEGFR Proteins 0.000 claims 1
- 230000001839 systemic circulation Effects 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
- 230000000472 traumatic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361845064P | 2013-07-11 | 2013-07-11 | |
| US61/845,064 | 2013-07-11 | ||
| PCT/IB2014/062978 WO2015004616A1 (en) | 2013-07-11 | 2014-07-09 | Use of a vegf antagonist in treating chorioretinal neovascular and permeability disorders in paediatric patients |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016528202A JP2016528202A (ja) | 2016-09-15 |
| JP2016528202A5 true JP2016528202A5 (enExample) | 2017-08-10 |
Family
ID=51211282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016524930A Pending JP2016528202A (ja) | 2013-07-11 | 2014-07-09 | 小児患者の脈絡網膜血管新生障害および透過性障害の治療におけるｖｅｇｆアンタゴニストの使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20160168240A1 (enExample) |
| EP (1) | EP3019526A1 (enExample) |
| JP (1) | JP2016528202A (enExample) |
| KR (1) | KR20160029794A (enExample) |
| CN (1) | CN105377891A (enExample) |
| AU (2) | AU2014288837A1 (enExample) |
| BR (1) | BR112016000177A2 (enExample) |
| CA (1) | CA2917807A1 (enExample) |
| MX (1) | MX2016000384A (enExample) |
| RU (1) | RU2676274C2 (enExample) |
| WO (1) | WO2015004616A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2473565C2 (ru) | 2006-04-07 | 2013-01-27 | Аерпио Терапетикс, Инк. | АНТИТЕЛА, СВЯЗЫВАЮЩИЕ ТИРОЗИН ФОСФАТАЗУ БЕТА ЧЕЛОВЕКА (HPTPβ), И ИХ ИСПОЛЬЗОВАНИЕ |
| US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| CN105412094A (zh) | 2009-07-06 | 2016-03-23 | 爱尔皮奥治疗有限公司 | 用于防止癌细胞转移的化合物、组合物和方法 |
| MX363351B (es) | 2011-10-13 | 2019-03-20 | Aerpio Therapeutics Inc | Un agente de unión a hptp?-ecd para usarse en el tratamiento de síndrome de fuga vascular. |
| US20150050277A1 (en) | 2013-03-15 | 2015-02-19 | Aerpio Therapeutics Inc. | Compositions and methods for treating ocular diseases |
| JP6483148B2 (ja) | 2014-03-14 | 2019-03-13 | エアーピオ セラピューティクス インコーポレイテッド | ＨＰＴＰ−β阻害剤 |
| CA2947456C (en) * | 2014-05-12 | 2023-03-14 | Formycon Ag | Pre-filled plastic syringe containing a vegf antagonist |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| EP3977994B1 (en) | 2015-09-23 | 2024-04-24 | EyePoint Pharmaceuticals, Inc. | Activators of tie-2 for use in treating intraocular pressure |
| MX2018006171A (es) * | 2015-11-18 | 2018-12-19 | Formycon Ag | Jeringa de plastico precargada que contiene un antagonista de vegf. |
| WO2017084616A1 (en) * | 2015-11-19 | 2017-05-26 | Zhuhai Tairuishang Biopharm Ltd. | Methods and compositions for binding vegf |
| WO2017117464A1 (en) | 2015-12-30 | 2017-07-06 | Kodiak Sciences Inc. | Antibodies and conjugates thereof |
| EP3454903A4 (en) * | 2016-05-13 | 2020-08-19 | Askgene Pharma, Inc. | NEW DOUBLE ANTAGONISTS OF ANGIOPOIETIN 2, VEGF |
| US10253094B2 (en) | 2016-07-20 | 2019-04-09 | Aerpio Therapeutics, Inc. | Antibodies that target human protein tyrosine phosphatase-beta (HPTP-beta) and methods of use thereof to treat ocular conditions |
| TW201836646A (zh) * | 2017-01-25 | 2018-10-16 | 美商艾康尼醫療股份有限公司 | 治療與血管生成及血管新生相關病症的方法 |
| EP3618923A4 (en) * | 2017-05-01 | 2020-03-11 | Ojai Retinal Technology, LLC | SYSTEM AND METHOD FOR TREATING MYOPIA |
| JP2021503496A (ja) * | 2017-11-16 | 2021-02-12 | イヴェリック・バイオ・インコーポレイテッド | 特発性ポリープ状脈絡膜血管症（ｉｐｃｖ）の処置方法又は予防方法 |
| BR112020017872A2 (pt) | 2018-03-02 | 2020-12-22 | Kodiak Sciences Inc. | Anticorpos de il-6 e construtos de fusão e conjugados dos mesmos |
| CN114269341A (zh) | 2019-04-29 | 2022-04-01 | 视点制药公司 | 靶向施莱姆管的Tie-2激活剂 |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| CN114845718B (zh) * | 2019-12-19 | 2025-05-16 | 活跃生物技术有限公司 | 用于治疗与过度血管形成相关的眼部疾病的化合物 |
| RU2762991C1 (ru) * | 2021-09-06 | 2021-12-24 | федеральное государственное автономное учреждение "Национальный медицинский исследовательский центр "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Способ лечения макулярного отека вследствие окклюзии ветви центральной вены сетчатки в сочетании с ретинальной артериолярной макроаневризмой |
| WO2025036488A1 (en) * | 2023-08-17 | 2025-02-20 | Innovent Biologics (Suzhou) Co., Ltd. | Methods of treating age-related macular degeneration and diabetic macular edema |
| CN118085112B (zh) * | 2024-04-29 | 2024-08-09 | 上海鼎新基因科技有限公司 | 抗多个vegf家族蛋白的融合蛋白及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4677538B2 (ja) | 2001-06-12 | 2011-04-27 | ジョンズ ホプキンズ ユニヴァーシティ スクール オヴ メディシン | 眼内薬物送達のためのリザーバデバイス |
| WO2005110374A1 (en) | 2004-04-30 | 2005-11-24 | Allergan, Inc. | Intraocular drug delivery systems containing a therapeutic component, a cyclodextrin, and a polymeric component |
| DK1767546T3 (da) | 2004-06-08 | 2012-04-23 | Chengdu Kanghong Biotechnologies Co Ltd | Angiogenese-inhiberende kimært protein og dets anvendelse |
| US20070072933A1 (en) * | 2005-09-26 | 2007-03-29 | Peyman Gholam A | Delivery of an ocular agent |
| US8039010B2 (en) | 2006-11-03 | 2011-10-18 | Allergan, Inc. | Sustained release intraocular drug delivery systems comprising a water soluble therapeutic agent and a release modifier |
| RU2010138799A (ru) * | 2008-02-21 | 2012-03-27 | Иста Фармасьютикалз (Us) | Офтальмологические нестероидные противовоспалительные средства в качестве адъювантов |
| EP2349339A4 (en) * | 2008-10-16 | 2015-01-07 | Kathleen Cogan Farinas | EXTENDED MEDICATION DELIVERY SYSTEM |
| ES2836948T3 (es) * | 2008-11-03 | 2021-06-28 | Molecular Partners Ag | Proteínas de unión que inhiben la interacción del receptor de VEGF-A |
| US9226917B2 (en) * | 2008-12-16 | 2016-01-05 | Valeant Pharmaceuticals International, Inc. | Photodynamic therapy for conditions of the eye |
| SG173167A1 (en) | 2009-01-29 | 2011-08-29 | Forsight Labs Llc | Posterior segment drug delivery |
| WO2010127029A1 (en) * | 2009-05-01 | 2010-11-04 | Ophthotech Corporation | Methods for treating or preventing ophthalmological diseases |
| TWI510246B (zh) | 2010-04-30 | 2015-12-01 | Molecular Partners Ag | 抑制ｖｅｇｆ－ａ受體交互作用的經修飾結合性蛋白質 |
| RU2469734C2 (ru) * | 2010-09-02 | 2012-12-20 | Григорий Владимирович Пантелеев | Лечебное средство для лечения расстройств аккомодаций "stiak" |
-
2014
- 2014-07-09 KR KR1020167000239A patent/KR20160029794A/ko not_active Withdrawn
- 2014-07-09 CN CN201480039606.4A patent/CN105377891A/zh active Pending
- 2014-07-09 BR BR112016000177A patent/BR112016000177A2/pt not_active IP Right Cessation
- 2014-07-09 AU AU2014288837A patent/AU2014288837A1/en not_active Abandoned
- 2014-07-09 CA CA2917807A patent/CA2917807A1/en not_active Abandoned
- 2014-07-09 EP EP14741406.4A patent/EP3019526A1/en not_active Withdrawn
- 2014-07-09 RU RU2016104397A patent/RU2676274C2/ru not_active IP Right Cessation
- 2014-07-09 WO PCT/IB2014/062978 patent/WO2015004616A1/en not_active Ceased
- 2014-07-09 US US14/903,749 patent/US20160168240A1/en not_active Abandoned
- 2014-07-09 JP JP2016524930A patent/JP2016528202A/ja active Pending
- 2014-07-09 MX MX2016000384A patent/MX2016000384A/es unknown
-
2017
- 2017-06-09 AU AU2017203923A patent/AU2017203923B2/en not_active Ceased
-
2018
- 2018-02-27 US US15/906,421 patent/US20180194835A1/en not_active Abandoned
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