|
US3301855A
(en)
|
1963-04-22 |
1967-01-31 |
Ciba Geigy Corp |
Derivatives of 4-nu-(2-nu, nu-dimethylaminolower alkyl)-amino quinazoline
|
|
GB1524747A
(en)
|
1976-05-11 |
1978-09-13 |
Ici Ltd |
Polypeptide
|
|
ATE28864T1
(de)
|
1982-07-23 |
1987-08-15 |
Ici Plc |
Amide-derivate.
|
|
GB8327256D0
(en)
|
1983-10-12 |
1983-11-16 |
Ici Plc |
Steroid derivatives
|
|
US5093330A
(en)
|
1987-06-15 |
1992-03-03 |
Ciba-Geigy Corporation |
Staurosporine derivatives substituted at methylamino nitrogen
|
|
US5010099A
(en)
|
1989-08-11 |
1991-04-23 |
Harbor Branch Oceanographic Institution, Inc. |
Discodermolide compounds, compositions containing same and method of preparation and use
|
|
NZ243082A
(en)
|
1991-06-28 |
1995-02-24 |
Ici Plc |
4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof
|
|
AU661533B2
(en)
|
1992-01-20 |
1995-07-27 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
TW225528B
(enExample)
|
1992-04-03 |
1994-06-21 |
Ciba Geigy Ag |
|
|
GB9314893D0
(en)
|
1993-07-19 |
1993-09-01 |
Zeneca Ltd |
Quinazoline derivatives
|
|
DE69522717T2
(de)
|
1995-03-30 |
2002-02-14 |
Pfizer Inc., New York |
Chinazolinderivate
|
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5843901A
(en)
|
1995-06-07 |
1998-12-01 |
Advanced Research & Technology Institute |
LHRH antagonist peptides
|
|
ATE212993T1
(de)
|
1995-07-06 |
2002-02-15 |
Novartis Erfind Verwalt Gmbh |
Pyrolopyrimidine und verfahren zu ihrer herstellung
|
|
US5760041A
(en)
|
1996-02-05 |
1998-06-02 |
American Cyanamid Company |
4-aminoquinazoline EGFR Inhibitors
|
|
GB9603095D0
(en)
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline derivatives
|
|
HU228446B1
(en)
|
1996-04-12 |
2013-03-28 |
Warner Lambert Co |
Kinazoline derivatives as irreversible inhibitors of protein-kinase, pharmaceutical compositions containing these compounds and use thereof
|
|
DE69734513T2
(de)
|
1996-06-24 |
2006-07-27 |
Pfizer Inc. |
Phenylamino-substituierte tricyclische derivate zur behandlung hyperproliferativer krankheiten
|
|
EP0923583A1
(de)
|
1996-08-30 |
1999-06-23 |
Novartis AG |
Verfahren zur herstellung von epothilonen und zwischenprodukte innerhalb des verfahrens
|
|
EP0938597B1
(en)
|
1996-09-06 |
2003-08-20 |
Obducat Aktiebolag |
Method for anisotropic etching of structures in conducting materials
|
|
WO1998010767A2
(en)
|
1996-09-13 |
1998-03-19 |
Sugen, Inc. |
Use of quinazoline derivatives for the manufacture of a medicament in the treatment of hyperproliferative skin disorders
|
|
EP0837063A1
(en)
|
1996-10-17 |
1998-04-22 |
Pfizer Inc. |
4-Aminoquinazoline derivatives
|
|
ES2312695T3
(es)
|
1996-11-18 |
2009-03-01 |
Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) |
Epotilones e y f.
|
|
US6441186B1
(en)
|
1996-12-13 |
2002-08-27 |
The Scripps Research Institute |
Epothilone analogs
|
|
CO4940418A1
(es)
|
1997-07-18 |
2000-07-24 |
Novartis Ag |
Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
|
|
GB9721069D0
(en)
|
1997-10-03 |
1997-12-03 |
Pharmacia & Upjohn Spa |
Polymeric derivatives of camptothecin
|
|
US6194181B1
(en)
|
1998-02-19 |
2001-02-27 |
Novartis Ag |
Fermentative preparation process for and crystal forms of cytostatics
|
|
IL138113A0
(en)
|
1998-02-25 |
2001-10-31 |
Sloan Kettering Inst Cancer |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
WO2000009495A1
(en)
|
1998-08-11 |
2000-02-24 |
Novartis Ag |
Isoquinoline derivatives with angiogenesis inhibiting activity
|
|
US6303342B1
(en)
|
1998-11-20 |
2001-10-16 |
Kason Biosciences, Inc. |
Recombinant methods and materials for producing epothilones C and D
|
|
WO2001070737A2
(en)
|
2000-03-20 |
2001-09-27 |
Sepracor, Inc. |
Therapeutic heterocyclic compounds for the treatment of asthma and allergy and use thereof
|
|
MXPA02010618A
(es)
|
2000-04-25 |
2004-05-05 |
Icos Corp |
Inhibidores de fosfatidilinositol 3-quinasa delta.
|
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
|
US6608053B2
(en)
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
PE20020354A1
(es)
|
2000-09-01 |
2002-06-12 |
Novartis Ag |
Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
|
|
AU2002214546A1
(en)
|
2000-09-29 |
2002-04-08 |
Cor Therapeutics, Inc. |
Bicyclic pyrimidin-4-one based inhibitors of factor xa
|
|
TWI238824B
(en)
|
2001-05-14 |
2005-09-01 |
Novartis Ag |
4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives
|
|
GB0119249D0
(en)
|
2001-08-07 |
2001-10-03 |
Novartis Ag |
Organic compounds
|
|
TW200306839A
(en)
|
2002-02-06 |
2003-12-01 |
Novartis Ag |
Quinazolinone derivatives and their use as CB agonists
|
|
ES2361403T3
(es)
|
2002-03-07 |
2011-06-16 |
X-Ceptor Therapeutics, Inc. |
Moduladores de quinazolinona de receptores nucleares.
|
|
EP1537089A4
(en)
|
2002-07-23 |
2008-04-16 |
Cytokinetics Inc |
CONNECTIONS, COMPOSITIONS AND PROCEDURES
|
|
EP1407774A1
(en)
|
2002-09-10 |
2004-04-14 |
LION Bioscience AG |
2-Amino-4-quinazolinones as LXR nuclear receptor binding compounds
|
|
EP1558083A4
(en)
|
2002-09-30 |
2008-04-16 |
Cytokinetics Inc |
COMPOUNDS, COMPOSITIONS AND METHODS
|
|
EP1578411A4
(en)
|
2002-12-09 |
2007-05-02 |
Univ Texas |
PROCESS FOR THE SELECTIVE INHIBITION OF JANUS TYROSINE KINASE3 (JAK3)
|
|
US20040242568A1
(en)
|
2003-03-25 |
2004-12-02 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
|
WO2005016349A1
(en)
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Methods of inhibiting leukocyte accumulation
|
|
WO2005016348A1
(en)
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Method of inhibiting immune responses stimulated by an endogenous factor
|
|
JP2005097276A
(ja)
*
|
2003-08-22 |
2005-04-14 |
Takeda Chem Ind Ltd |
縮合ピリミジン誘導体およびその用途
|
|
CA2552664A1
(en)
|
2004-01-08 |
2005-07-28 |
Michigan State University |
Methods for treating and preventing hypertension and hypertension-related disorders
|
|
DK1704145T3
(da)
|
2004-01-12 |
2012-09-24 |
Ym Biosciences Australia Pty |
Selektive kinaseinhibitorer
|
|
WO2005091711A2
(en)
|
2004-03-24 |
2005-10-06 |
Orchid Chemicals & Pharmaceuticals Ltd |
Novel condensed pyrimidones
|
|
CA2566436C
(en)
|
2004-05-13 |
2011-05-10 |
Vanderbilt University |
Phosphoinositide 3-kinase delta selective inhibitors for inhibiting angiogenesis
|
|
PL1761540T3
(pl)
*
|
2004-05-13 |
2017-06-30 |
Icos Corporation |
Chinazolinony jako inhibitory ludzkiej kinazy 3-fosfatydyloinozytolu delta
|
|
JP2008500338A
(ja)
|
2004-05-25 |
2008-01-10 |
イコス・コーポレイション |
造血細胞の異常増殖を治療及び/又は予防する方法
|
|
EP1750715A1
(en)
|
2004-06-04 |
2007-02-14 |
Icos Corporation |
Methods for treating mast cell disorders
|
|
GB0413618D0
(en)
|
2004-06-17 |
2004-07-21 |
Novartis Ag |
Organic compounds
|
|
US7939538B2
(en)
|
2004-06-28 |
2011-05-10 |
Amgen Inc. |
Compounds, compositions and methods for prevention and treatment of inflammatory and immunoregulatory disorders and diseases
|
|
EP1885356A2
(en)
|
2005-02-17 |
2008-02-13 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
|
WO2006116401A1
(en)
*
|
2005-04-28 |
2006-11-02 |
Bristol-Myers Squibb Company |
C-5 substituted quinazolinone derivatives as selective estrogen receptor beta modulators
|
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
|
GB0525068D0
(en)
*
|
2005-12-08 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
KR101499783B1
(ko)
|
2006-04-04 |
2015-03-09 |
더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 |
키나제 길항물질
|
|
SG178786A1
(en)
|
2006-11-13 |
2012-03-29 |
Lilly Co Eli |
Thienopyrimidinones for treatment of inflammatory disorders and cancers
|
|
WO2008064244A2
(en)
|
2006-11-20 |
2008-05-29 |
The Trustees Of Columbia University In The City Of New York |
Phosphoinositide modulation for the treatment of neurodegenerative diseases
|
|
JP2010512738A
(ja)
|
2006-12-14 |
2010-04-30 |
メディカル リサーチ カウンシル |
方法及び使用
|
|
WO2008076447A2
(en)
|
2006-12-15 |
2008-06-26 |
Ordway Research Institute |
Treatments of therapy-resistant diseases comprising drug combinations
|
|
WO2009036768A2
(en)
|
2007-09-19 |
2009-03-26 |
H. Lundbeck A/S |
Diagnosing potential weight gain in a subject
|
|
WO2009058361A1
(en)
|
2007-10-31 |
2009-05-07 |
Dynavax Technologies Corp. |
Inhibition of type i ifn production
|
|
AU2009204483B2
(en)
|
2008-01-04 |
2014-03-13 |
Intellikine, Llc |
Certain chemical entities, compositions and methods
|
|
NZ631024A
(en)
|
2008-11-13 |
2016-04-29 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
|
US20110269779A1
(en)
|
2008-11-18 |
2011-11-03 |
Intellikine, Inc. |
Methods and compositions for treatment of ophthalmic conditions
|
|
US20110294803A1
(en)
|
2008-12-04 |
2011-12-01 |
Law Amanda J |
Phosphatidylinositol-3-kinase p110 delta-targeted drugs in the treatment of cns disorders
|
|
WO2010083163A1
(en)
|
2009-01-13 |
2010-07-22 |
Philadelphia Health And Education Corporation |
The role of p110 delta signaling in morbidity and lung pathology induced by influenza virus infection
|
|
SG174529A1
(en)
|
2009-03-24 |
2011-10-28 |
Gilead Calistoga Llc |
Atropisomers of2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
|
|
PT2421536E
(pt)
|
2009-04-20 |
2015-10-20 |
Gilead Calistoga Llc |
Métodos de tratamento para tumores sólidos
|
|
EP2456443A1
(en)
*
|
2009-07-21 |
2012-05-30 |
Gilead Calistoga LLC |
Treatment of liver disorders with pi3k inhibitors
|
|
WO2011031896A2
(en)
|
2009-09-09 |
2011-03-17 |
Avila Therapeutics, Inc. |
Pi3 kinase inhibitors and uses thereof
|
|
US20120231015A1
(en)
|
2009-11-06 |
2012-09-13 |
Emory University |
Fragile x mental retardation protein (fmrp), compositions, and methods related thereto
|
|
US20110269244A1
(en)
|
2009-12-30 |
2011-11-03 |
Petter Russell C |
Ligand-directed covalent modification of protein
|
|
JP5951600B2
(ja)
|
2010-05-21 |
2016-07-13 |
インフィニティー ファーマシューティカルズ, インコーポレイテッド |
キナーゼ調節のための、化合物、組成物および方法
|
|
UA112517C2
(uk)
|
2010-07-06 |
2016-09-26 |
Новартіс Аг |
Тетрагідропіридопіримідинові похідні
|
|
WO2012028757A1
(es)
|
2010-09-02 |
2012-03-08 |
Universitat De Barcelona |
Tiazoles fluorados útiles para el tratamiento del cáncer
|
|
IT1403156B1
(it)
|
2010-12-01 |
2013-10-04 |
Università Degli Studi Di Torino |
Inibitori di fosfatidilinositol 3-chinasi, relative composizioni ed usi.
|
|
CN102838600A
(zh)
|
2011-06-24 |
2012-12-26 |
山东亨利医药科技有限责任公司 |
苯基喹唑啉类PI3Kδ抑制剂
|
|
CN102838601A
(zh)
|
2011-06-24 |
2012-12-26 |
山东亨利医药科技有限责任公司 |
选择性磷酰肌醇3-激酶δ抑制剂
|
|
CN103930422A
(zh)
*
|
2011-07-19 |
2014-07-16 |
无限药品股份有限公司 |
杂环化合物及其用途
|
|
CN103998442B
(zh)
*
|
2011-08-29 |
2016-09-14 |
无限药品股份有限公司 |
杂环化合物及其用途
|
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
WO2014014814A1
(en)
|
2012-07-16 |
2014-01-23 |
Brown University |
Compounds for the treatment and prevention of infections
|
|
WO2014015523A1
(en)
|
2012-07-27 |
2014-01-30 |
Hutchison Medipharma Limited |
Novel heteroaryl and heterocycle compounds, compositions and methods
|
|
EP2935246B1
(en)
|
2012-12-21 |
2018-07-25 |
Gilead Calistoga LLC |
Isoquinolinone or quinazolinone phosphatidylinositol 3-kinase inhibitors
|
|
EP2941426B1
(en)
|
2012-12-21 |
2018-06-13 |
Gilead Calistoga LLC |
Substituted pyrimidine aminoalkyl-quinazolones as phosphatidylinositol 3-kinase inhibitors
|
|
WO2014128612A1
(en)
*
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Quinazolin-4-one derivatives
|