JP2016512429A5 - - Google Patents
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- JP2016512429A5 JP2016512429A5 JP2016501461A JP2016501461A JP2016512429A5 JP 2016512429 A5 JP2016512429 A5 JP 2016512429A5 JP 2016501461 A JP2016501461 A JP 2016501461A JP 2016501461 A JP2016501461 A JP 2016501461A JP 2016512429 A5 JP2016512429 A5 JP 2016512429A5
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- sequence
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- 239000003153 chemical reaction reagent Substances 0.000 claims 33
- 238000000034 method Methods 0.000 claims 31
- 239000000523 sample Substances 0.000 claims 25
- 238000001514 detection method Methods 0.000 claims 18
- 239000012491 analyte Substances 0.000 claims 16
- 108091034117 Oligonucleotide Proteins 0.000 claims 11
- 230000000295 complement effect Effects 0.000 claims 9
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 8
- 108091023037 Aptamer Proteins 0.000 claims 4
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims 4
- 230000003321 amplification Effects 0.000 claims 4
- 229960002685 biotin Drugs 0.000 claims 4
- 235000020958 biotin Nutrition 0.000 claims 4
- 239000011616 biotin Substances 0.000 claims 4
- 239000003446 ligand Substances 0.000 claims 4
- 238000003199 nucleic acid amplification method Methods 0.000 claims 4
- 239000002853 nucleic acid probe Substances 0.000 claims 4
- 150000007523 nucleic acids Chemical group 0.000 claims 4
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 238000011901 isothermal amplification Methods 0.000 claims 3
- 238000003752 polymerase chain reaction Methods 0.000 claims 3
- 108090001008 Avidin Proteins 0.000 claims 2
- 108010090804 Streptavidin Proteins 0.000 claims 2
- 238000007834 ligase chain reaction Methods 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 238000005096 rolling process Methods 0.000 claims 2
- 108060004795 Methyltransferase Proteins 0.000 claims 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 1
- 238000002835 absorbance Methods 0.000 claims 1
- -1 antibody Substances 0.000 claims 1
- 238000000149 argon plasma sintering Methods 0.000 claims 1
- 230000029918 bioluminescence Effects 0.000 claims 1
- 238000005415 bioluminescence Methods 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 238000006073 displacement reaction Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361779050P | 2013-03-13 | 2013-03-13 | |
| US61/779,050 | 2013-03-13 | ||
| US201361919887P | 2013-12-23 | 2013-12-23 | |
| US61/919,887 | 2013-12-23 | ||
| PCT/US2014/024279 WO2014165061A1 (en) | 2013-03-13 | 2014-03-12 | Improved assay methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512429A JP2016512429A (ja) | 2016-04-28 |
| JP2016512429A5 true JP2016512429A5 (cg-RX-API-DMAC7.html) | 2017-03-23 |
| JP6408552B2 JP6408552B2 (ja) | 2018-10-17 |
Family
ID=51528698
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016501461A Active JP6408552B2 (ja) | 2013-03-13 | 2014-03-12 | 改善されたアッセイ方法 |
| JP2016502025A Active JP6289604B2 (ja) | 2013-03-13 | 2014-03-13 | 改善されたアッセイ方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502025A Active JP6289604B2 (ja) | 2013-03-13 | 2014-03-13 | 改善されたアッセイ方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US9618510B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP2971183A4 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6408552B2 (cg-RX-API-DMAC7.html) |
| KR (5) | KR20220038550A (cg-RX-API-DMAC7.html) |
| CN (5) | CN110308272B (cg-RX-API-DMAC7.html) |
| AU (5) | AU2014248759B2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2904181A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2972351T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2901952T3 (cg-RX-API-DMAC7.html) |
| HK (2) | HK1213019A1 (cg-RX-API-DMAC7.html) |
| WO (2) | WO2014165061A1 (cg-RX-API-DMAC7.html) |
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| KR102497054B1 (ko) | 2014-05-15 | 2023-02-06 | 메소 스케일 테크놀러지즈, 엘엘시 | 개선된 분석 방법 |
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