JP2016505551A5 - - Google Patents

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Publication number
JP2016505551A5
JP2016505551A5 JP2015545760A JP2015545760A JP2016505551A5 JP 2016505551 A5 JP2016505551 A5 JP 2016505551A5 JP 2015545760 A JP2015545760 A JP 2015545760A JP 2015545760 A JP2015545760 A JP 2015545760A JP 2016505551 A5 JP2016505551 A5 JP 2016505551A5
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JP
Japan
Prior art keywords
alkyl
group
heterocyclyl
cycloalkyl
heteroaryl
Prior art date
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Application number
JP2015545760A
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English (en)
Japanese (ja)
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JP2016505551A (ja
JP6283862B2 (ja
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Publication date
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Priority claimed from PCT/EP2013/075238 external-priority patent/WO2014086712A1/en
Publication of JP2016505551A publication Critical patent/JP2016505551A/ja
Publication of JP2016505551A5 publication Critical patent/JP2016505551A5/ja
Application granted granted Critical
Publication of JP6283862B2 publication Critical patent/JP6283862B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015545760A 2012-12-07 2013-12-02 新規インダニルオキシジヒドロベンゾフラニル酢酸 Expired - Fee Related JP6283862B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12196011.6 2012-12-07
EP12196011 2012-12-07
PCT/EP2013/075238 WO2014086712A1 (en) 2012-12-07 2013-12-02 New indanyloxydihydrobenzofuranylacetic acids

Publications (3)

Publication Number Publication Date
JP2016505551A JP2016505551A (ja) 2016-02-25
JP2016505551A5 true JP2016505551A5 (enExample) 2017-01-19
JP6283862B2 JP6283862B2 (ja) 2018-02-28

Family

ID=47290800

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015545760A Expired - Fee Related JP6283862B2 (ja) 2012-12-07 2013-12-02 新規インダニルオキシジヒドロベンゾフラニル酢酸

Country Status (7)

Country Link
US (2) US20140163025A1 (enExample)
EP (1) EP2928886B1 (enExample)
JP (1) JP6283862B2 (enExample)
AR (1) AR093864A1 (enExample)
TW (1) TW201439076A (enExample)
UY (1) UY35171A (enExample)
WO (1) WO2014086712A1 (enExample)

Families Citing this family (26)

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Publication number Priority date Publication date Assignee Title
US20140163025A1 (en) 2012-12-07 2014-06-12 Boehringer Ingelheim International Gmbh Indanyloxydihydrobenzofuranylacetic acids
SI3043784T1 (sl) * 2013-09-09 2019-08-30 Peloton Therapeutics, Inc. Aril etri in njihova uporaba
EA201690888A1 (ru) 2013-11-14 2016-10-31 Кадила Хелзкэр Лимитед Новые гетероциклические соединения
ES2737148T3 (es) 2013-12-16 2020-01-10 Peloton Therapeutics Inc Análogos de sulfona y sulfoximina cíclicos y usos de los mismos
CN104177320B (zh) * 2014-08-27 2016-03-02 广东东阳光药业有限公司 一种脲取代联苯类化合物及其组合物及用途
WO2016144825A1 (en) * 2015-03-11 2016-09-15 Peloton Therapeutics, Inc. Aromatic compounds and uses thereof
US10512626B2 (en) 2015-03-11 2019-12-24 Peloton Therapeautics, Inc. Compositions for use in treating glioblastoma
EP3267792A4 (en) 2015-03-11 2018-09-26 Peloton Therapeutics, Inc. Compositions for use in treating pulmonary arterial hypertension
WO2016144826A1 (en) 2015-03-11 2016-09-15 Peloton Therapeutics, Inc. Substituted pyridines and uses thereof
WO2016168510A1 (en) 2015-04-17 2016-10-20 Peloton Therapeutics, Inc. Combination therapy of a hif-2-alpha inhibitor and an immunotherapeutic agent and uses thereof
CN112898269A (zh) * 2016-04-29 2021-06-04 拜耳医药股份有限公司 化合物的结晶形式
EA035867B1 (ru) * 2016-04-29 2020-08-24 Байер Фарма Акциенгезельшафт Синтез индазолов
WO2018138029A1 (en) 2017-01-26 2018-08-02 Boehringer Ingelheim International Gmbh Benzyloxypyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
WO2018138030A1 (en) 2017-01-26 2018-08-02 Boehringer Ingelheim International Gmbh Benzyloxypyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
US10919859B2 (en) 2017-01-26 2021-02-16 Boehringer Ingelheim International Gmbh Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
JP7049349B2 (ja) 2017-01-26 2022-04-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンジルアミノピラジニルシクロプロパンカルボン酸、その医薬組成物及び使用
US10550127B1 (en) 2017-02-08 2020-02-04 Boehringer Ingelheim International Gmbh Indanylaminoazadihydrobenzofuranylacetic acids, pharmaceutical compositions for the treatment of diabetes
US11098026B2 (en) 2017-03-13 2021-08-24 Impetis Biosciences Limited Fused bicyclic compounds, compositions and applications thereof
KR102708681B1 (ko) 2018-02-13 2024-09-26 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제
EP3781556B1 (en) 2018-04-19 2025-06-18 Gilead Sciences, Inc. Pd-1/pd-l1 inhibitors
CN118221646A (zh) 2018-07-13 2024-06-21 吉利德科学公司 Pd-1/pd-l1抑制剂
KR102635333B1 (ko) 2018-10-24 2024-02-15 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제
WO2021071837A1 (en) 2019-10-07 2021-04-15 Kallyope, Inc. Gpr119 agonists
TW202140440A (zh) 2020-02-28 2021-11-01 美商克力歐普股份有限公司 Gpr40激動劑
EP4153589A4 (en) 2020-05-19 2024-06-12 Kallyope, Inc. AMPK ACTIVATORS
WO2021263039A1 (en) 2020-06-26 2021-12-30 Kallyope, Inc. Ampk activators

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003277576A1 (en) 2002-11-08 2004-06-07 Takeda Pharmaceutical Company Limited Receptor function controlling agent
US7135575B2 (en) 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
WO2004106276A1 (ja) 2003-05-30 2004-12-09 Takeda Pharmaceutical Company Limited 縮合環化合物
JP4805552B2 (ja) * 2003-05-30 2011-11-02 武田薬品工業株式会社 縮合環化合物
WO2005087710A1 (ja) * 2004-03-15 2005-09-22 Takeda Pharmaceutical Company Limited アミノフェニルプロパン酸誘導体
CA2621949A1 (en) 2005-09-14 2007-03-22 Amgen Inc. Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders
WO2007114213A1 (ja) 2006-03-30 2007-10-11 Asahi Kasei Pharma Corporation 置換二環式環状誘導体及びその用途
JO2969B1 (en) * 2006-06-27 2016-03-15 تاكيدا فارماسويتيكال كمبني ليمتد Welded circular compounds
WO2009157418A1 (ja) 2008-06-25 2009-12-30 第一三共株式会社 カルボン酸化合物
EP2358656B1 (en) 2008-10-15 2014-01-01 Amgen, Inc Spirocyclic gpr40 modulators
US20120172351A1 (en) 2009-06-09 2012-07-05 Nobuyuki Negoro Novel fused cyclic compound and use thereof
TWI543984B (zh) 2010-07-09 2016-08-01 艾伯維公司 作為s1p調節劑的螺-哌啶衍生物
AR084050A1 (es) 2010-12-01 2013-04-17 Boehringer Ingelheim Int Acidos indaniloxidihidrobenzofuranilaceticos
CA2889783A1 (en) 2012-11-28 2014-06-05 Boehringer Ingelheim International Gmbh New indanyloxydihydrobenzofuranylacetic acids
US20140163025A1 (en) 2012-12-07 2014-06-12 Boehringer Ingelheim International Gmbh Indanyloxydihydrobenzofuranylacetic acids

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