JP2016504922A5 - - Google Patents

Info

Publication number

JP2016504922A5

JP2016504922A5 JP2015555816A JP2015555816A JP2016504922A5 JP 2016504922 A5 JP2016504922 A5 JP 2016504922A5 JP 2015555816 A JP2015555816 A JP 2015555816A JP 2015555816 A JP2015555816 A JP 2015555816A JP 2016504922 A5 JP2016504922 A5 JP 2016504922A5

Authority

JP

Japan

Prior art keywords

seq

mar

tep

transgene

nucleic acid

Prior art date

2014-02-01

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 108700019146 Transgenes Proteins 0.000 claims 21
• 150000007523 nucleic acids Chemical group 0.000 claims 20
• 108020004707 nucleic acids Proteins 0.000 claims 17
• 102000039446 nucleic acids Human genes 0.000 claims 17
• 108090000623 proteins and genes Proteins 0.000 claims 16
• 102000004169 proteins and genes Human genes 0.000 claims 15
• 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 13
• 239000013598 vector Substances 0.000 claims 13
• 210000004962 mammalian cell Anatomy 0.000 claims 9
• -1 Rad54 Proteins 0.000 claims 6
• 125000003275 alpha amino acid group Chemical group 0.000 claims 4
• 238000000034 method Methods 0.000 claims 4
• 238000005215 recombination Methods 0.000 claims 4
• 230000006798 recombination Effects 0.000 claims 4
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
• 241000426682 Salinispora Species 0.000 claims 3
• 238000000338 in vitro Methods 0.000 claims 3
• 238000011144 upstream manufacturing Methods 0.000 claims 3
• 101150072950 BRCA1 gene Proteins 0.000 claims 2
• 101150059668 Bard1 gene Proteins 0.000 claims 2
• 108091005753 BiP proteins Proteins 0.000 claims 2
• 101150008921 Brca2 gene Proteins 0.000 claims 2
• 102000006311 Cyclin D1 Human genes 0.000 claims 2
• 108010058546 Cyclin D1 Proteins 0.000 claims 2
• 102100033934 DNA repair protein RAD51 homolog 2 Human genes 0.000 claims 2
• 101100300807 Drosophila melanogaster spn-A gene Proteins 0.000 claims 2
• 241000287828 Gallus gallus Species 0.000 claims 2
• 102100027421 Heat shock cognate 71 kDa protein Human genes 0.000 claims 2
• 101001080568 Homo sapiens Heat shock cognate 71 kDa protein Proteins 0.000 claims 2
• 101000581326 Homo sapiens Mediator of DNA damage checkpoint protein 1 Proteins 0.000 claims 2
• 101001048454 Homo sapiens Protein Hook homolog 1 Proteins 0.000 claims 2
• 102000003960 Ligases Human genes 0.000 claims 2
• 108090000364 Ligases Proteins 0.000 claims 2
• 102100027643 Mediator of DNA damage checkpoint protein 1 Human genes 0.000 claims 2
• 108010006519 Molecular Chaperones Proteins 0.000 claims 2
• 102000016943 Muramidase Human genes 0.000 claims 2
• 108010014251 Muramidase Proteins 0.000 claims 2
• 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 claims 2
• 102100023602 Protein Hook homolog 1 Human genes 0.000 claims 2
• 102000053062 Rad52 DNA Repair and Recombination Human genes 0.000 claims 2
• 108700031762 Rad52 DNA Repair and Recombination Proteins 0.000 claims 2
• 108091027967 Small hairpin RNA Proteins 0.000 claims 2
• 102000008579 Transposases Human genes 0.000 claims 2
• 108010020764 Transposases Proteins 0.000 claims 2
• 210000004027 cell Anatomy 0.000 claims 2
• 239000013604 expression vector Substances 0.000 claims 2
• 229960000274 lysozyme Drugs 0.000 claims 2
• 235000010335 lysozyme Nutrition 0.000 claims 2
• 239000004325 lysozyme Substances 0.000 claims 2
• 108020004999 messenger RNA Proteins 0.000 claims 2
• 108091070501 miRNA Proteins 0.000 claims 2
• 239000002679 microRNA Substances 0.000 claims 2
• 101150071637 mre11 gene Proteins 0.000 claims 2
• 230000037361 pathway Effects 0.000 claims 2
• 230000008488 polyadenylation Effects 0.000 claims 2
• 230000022558 protein metabolic process Effects 0.000 claims 2
• 230000020978 protein processing Effects 0.000 claims 2
• 230000009962 secretion pathway Effects 0.000 claims 2
• 239000004055 small Interfering RNA Substances 0.000 claims 2
• 238000001890 transfection Methods 0.000 claims 2
• 241000699800 Cricetinae Species 0.000 claims 1
• 238000012258 culturing Methods 0.000 claims 1
• 230000010354 integration Effects 0.000 claims 1
• 239000011159 matrix material Substances 0.000 claims 1