|
US7803931B2
(en)
|
2004-02-12 |
2010-09-28 |
Archemix Corp. |
Aptamer therapeutics useful in the treatment of complement-related disorders
|
|
AR095196A1
(es)
|
2013-03-15 |
2015-09-30 |
Regeneron Pharma |
Medio de cultivo celular libre de suero
|
|
SG11201510315TA
(en)
|
2013-07-12 |
2016-01-28 |
Ophthotech Corp |
Methods for treating or preventing ophthalmological conditions
|
|
DE202014010499U1
(de)
|
2013-12-17 |
2015-10-20 |
Kymab Limited |
Targeting von humaner PCSK9 zur Cholesterinbehandlung
|
|
US9914769B2
(en)
|
2014-07-15 |
2018-03-13 |
Kymab Limited |
Precision medicine for cholesterol treatment
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
CN106164094B
(zh)
|
2014-03-21 |
2021-05-14 |
X博迪公司 |
双特异性抗原结合多肽
|
|
US9840553B2
(en)
|
2014-06-28 |
2017-12-12 |
Kodiak Sciences Inc. |
Dual PDGF/VEGF antagonists
|
|
WO2016075034A1
(en)
|
2014-11-10 |
2016-05-19 |
F. Hoffmann-La Roche Ag |
ANTI-IL-1beta ANTIBODIES AND METHODS OF USE
|
|
JP6946184B2
(ja)
*
|
2014-11-10 |
2021-10-06 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
抗ｐｄｇｆ−ｂ抗体及び使用法
|
|
KR20170080584A
(ko)
|
2014-11-10 |
2017-07-10 |
에프. 호프만-라 로슈 아게 |
이중특이적 항체 및 안과학에서 이의 사용 방법
|
|
SG11201703458UA
(en)
|
2014-11-10 |
2017-05-30 |
Hoffmann La Roche |
Anti-ang2 antibodies and methods of use
|
|
US20160144025A1
(en)
*
|
2014-11-25 |
2016-05-26 |
Regeneron Pharmaceuticals, Inc. |
Methods and formulations for treating vascular eye diseases
|
|
EP3253413A2
(en)
*
|
2015-02-06 |
2017-12-13 |
Kadmon Corporation, LLC |
Immunomodulatory agents
|
|
AU2016241499B2
(en)
*
|
2015-03-31 |
2020-12-17 |
Ildong Pharm Co., Ltd. |
Pharmaceutical composition for preventing and treating eye diseases, containing, as active ingredient, fusion protein in which tissue-penetrating peptide and anti-vascular endothelial growth factor preparation are fused
|
|
JP6916776B2
(ja)
|
2015-07-29 |
2021-08-11 |
アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ |
Ａｎｇ−２に対する重鎖のみ抗体
|
|
TWI797060B
(zh)
|
2015-08-04 |
2023-04-01 |
美商再生元醫藥公司 |
補充牛磺酸之細胞培養基及用法
|
|
CN114404371A
(zh)
|
2015-12-16 |
2022-04-29 |
瑞泽恩制药公司 |
制造蛋白质微粒的组合物和方法
|
|
JP7088454B2
(ja)
|
2015-12-30 |
2022-06-21 |
コディアック サイエンシーズ インコーポレイテッド |
抗体および抗体複合体
|
|
CN116903741A
(zh)
|
2016-06-20 |
2023-10-20 |
科马布有限公司 |
特异性结合于pd-l1的抗体或其抗原结合片段及其用途
|
|
CN109843918B
(zh)
*
|
2016-07-01 |
2023-08-25 |
旁分泌疗法公司 |
用于pdgf-cc抑制的方法和组合物
|
|
KR20230041834A
(ko)
|
2016-08-16 |
2023-03-24 |
리제너론 파아마슈티컬스, 인크. |
혼합물로부터 개별 항체들을 정량하는 방법
|
|
WO2018039499A1
(en)
|
2016-08-24 |
2018-03-01 |
Regeneron Pharmaceuticals, Inc. |
Host cell protein modification
|
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
CN109021104B
(zh)
*
|
2017-06-12 |
2022-08-12 |
上海睿智化学研究有限公司 |
一种抗人血小板衍生生长因子β受体的抗体及其应用
|
|
KR102782655B1
(ko)
|
2017-07-06 |
2025-03-14 |
리제너론 파마슈티칼스 인코포레이티드 |
당단백질을 만들기 위한 세포 배양 과정
|
|
EP3727629A1
(en)
|
2017-12-22 |
2020-10-28 |
Regeneron Pharmaceuticals, Inc. |
System and method for characterizing drug product impurities
|
|
CA3085177A1
(en)
|
2018-01-31 |
2019-08-08 |
Regeneron Pharamaceuticals, Inc. |
System and method for characterizing size and charge variant drug product impurities
|
|
TW202311746A
(zh)
|
2018-02-02 |
2023-03-16 |
美商再生元醫藥公司 |
用於表徵蛋白質二聚合之系統及方法
|
|
KR20200127979A
(ko)
|
2018-02-28 |
2020-11-11 |
리제너론 파마슈티칼스 인코포레이티드 |
바이러스 오염물질을 확인하기 위한 시스템 및 방법
|
|
CN112203679A
(zh)
|
2018-03-02 |
2021-01-08 |
科达制药股份有限公司 |
Il-6抗体及其融合构建体和缀合物
|
|
US12259355B2
(en)
|
2018-03-19 |
2025-03-25 |
Regeneron Pharmaceuticals, Inc. |
Microchip capillary electrophoresis assays and reagents
|
|
KR102503356B1
(ko)
|
2018-03-19 |
2023-02-24 |
리제너론 파마슈티칼스 인코포레이티드 |
마이크로칩 모세관 전기영동 분석 및 시약
|
|
US12253490B2
(en)
|
2018-03-19 |
2025-03-18 |
Regeneron Pharmaceuticals, Inc. |
Microchip capillary electrophoresis assays and reagents
|
|
GB201806918D0
(en)
*
|
2018-04-27 |
2018-06-13 |
Enleofen Bio Pte Ltd |
Combination treatment for eye fibrosis
|
|
CN108586611B
(zh)
*
|
2018-04-28 |
2021-01-26 |
暨南大学 |
重组全人源抗破伤风毒素单克隆抗体
|
|
TW202016125A
(zh)
|
2018-05-10 |
2020-05-01 |
美商再生元醫藥公司 |
用於定量及調節蛋白質黏度之系統與方法
|
|
KR20210052389A
(ko)
|
2018-08-27 |
2021-05-10 |
리제너론 파마슈티칼스 인코포레이티드 |
다운스트림 정제에서의 라만 분광법의 사용
|
|
CA3100038A1
(en)
|
2018-08-30 |
2020-03-05 |
Regeneron Pharmaceuticals, Inc. |
Methods for characterizing protein complexes
|
|
BR112021006352A2
(pt)
*
|
2018-10-05 |
2021-07-06 |
Univ Ewha Ind Collaboration |
anticorpo receptor de pdgf e uso do mesmo
|
|
SG11202104237YA
(en)
|
2019-01-16 |
2021-05-28 |
Regeneron Pharma |
Methods for identifying free thiols in proteins
|
|
ES2984072T3
(es)
*
|
2019-03-08 |
2024-10-28 |
Linxis B V |
Moléculas de unión internalizantes que actúan sobre receptores implicados en la proliferación celular o en ladiferenciación celular
|
|
MX2021013356A
(es)
|
2019-05-03 |
2022-03-11 |
Singapore Health Serv Pte Ltd |
Tratamiento y prevencion de enfermedades metabolicas.
|
|
CA3135004A1
(en)
|
2019-05-13 |
2020-11-19 |
Regeneron Pharmaceuticals, Inc. |
Improved competitive ligand binding assays
|
|
JP7635213B2
(ja)
|
2019-09-24 |
2025-02-25 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
クロマトグラフィーの使用および再生のためのシステムおよび方法
|
|
WO2021072265A1
(en)
|
2019-10-10 |
2021-04-15 |
Kodiak Sciences Inc. |
Methods of treating an eye disorder
|
|
US12297451B1
(en)
|
2019-10-25 |
2025-05-13 |
Regeneron Pharmaceuticals, Inc. |
Cell culture medium
|
|
MY207613A
(en)
|
2019-11-25 |
2025-03-06 |
Regeneron Pharma |
Sustained release formulations using non-aqueous emulsions
|
|
EP4087657A1
(en)
|
2020-01-08 |
2022-11-16 |
Synthis Therapeutics, Inc. |
Alk5 inhibitor conjugates and uses thereof
|
|
CA3165060C
(en)
|
2020-01-21 |
2023-06-20 |
Yiming Zhao |
Deglycosylation methods for electrophoresis of glycosylated proteins
|
|
CA3170712A1
(en)
*
|
2020-02-07 |
2021-08-12 |
Biorion Technologies B.V. |
Platelet derived growth factor receptor (pdgfr) antibodies, conjugates, compositions, and uses thereof.
|
|
JP2023542820A
(ja)
|
2020-08-31 |
2023-10-12 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
細胞培養成績を改善し、アスパラギン配列バリアントを軽減するためのアスパラギン供給戦略
|
|
EP4214235A1
(en)
*
|
2020-09-16 |
2023-07-26 |
LinXis B.V. |
Internalizing binding molecules
|
|
US12239687B2
(en)
|
2020-11-25 |
2025-03-04 |
Regeneron Pharmaceuticals, Inc. |
Sustained release formulations using non-aqueous membrane emulsification
|
|
EP4262757A1
(en)
|
2020-12-17 |
2023-10-25 |
Regeneron Pharmaceuticals, Inc. |
Fabrication of protein-encapsulating microgels
|
|
WO2022159432A1
(en)
|
2021-01-20 |
2022-07-28 |
Regeneron Pharmaceuticals, Inc. |
Methods of improving protein titer in cell culture
|
|
AU2022230987A1
(en)
|
2021-03-03 |
2023-08-31 |
Regeneron Pharmaceuticals, Inc. |
Systems and methods for quantifying and modifying protein viscosity
|
|
CA3211302A1
(en)
|
2021-03-26 |
2022-09-29 |
Ross Kenyon |
Methods and systems for developing mixing protocols
|
|
AU2022286340A1
(en)
|
2021-06-01 |
2024-01-04 |
Regeneron Pharmaceuticals, Inc. |
Microchip capillary electrophoresis assays and reagents
|
|
AR127006A1
(es)
|
2021-09-08 |
2023-12-06 |
Regeneron Pharma |
UN MÉTODO BASADO EN ESPECTROMETRÍA DE MASAS Y DE ALTO RENDIMIENTO PARA CUANTIFICAR ANTICUERPOS Y OTRAS PROTEÍNAS QUE CONTIENEN Fc
|
|
JP2024531800A
(ja)
|
2021-09-20 |
2024-08-29 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
抗体の不均一性を制御する方法
|
|
US20230110811A1
(en)
|
2021-10-07 |
2023-04-13 |
Regeneron Pharmaceuticals, Inc. |
pH METER CALIBRATION AND CORRECTION
|
|
EP4413364A2
(en)
|
2021-10-07 |
2024-08-14 |
Regeneron Pharmaceuticals, Inc. |
Systems and methods of ph modeling and control
|
|
AU2022376179A1
(en)
|
2021-10-26 |
2024-05-16 |
Regeneron Pharmaceuticals, Inc. |
Systems and methods for generating laboratory water and distributing laboratory water at different temperatures
|
|
WO2023177836A1
(en)
|
2022-03-18 |
2023-09-21 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for analyzing polypeptide variants
|
|
US11723955B1
(en)
|
2022-05-13 |
2023-08-15 |
Allgenesis Biotherapeutics Inc. |
VEGFR fusion protein pharmaceutical composition
|
|
US20240198253A1
(en)
|
2022-12-16 |
2024-06-20 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for assessing chromatographic column integrity
|
|
WO2024158961A1
(en)
|
2023-01-25 |
2024-08-02 |
Regeneron Pharmaceuticals, Inc. |
Mass spectrometry-based characterization of antibodies co-expressed in vivo
|
|
TW202445135A
(zh)
|
2023-01-25 |
2024-11-16 |
美商再生元醫藥公司 |
液態蛋白質組成物穩定性之建模方法
|
|
TW202445138A
(zh)
|
2023-02-01 |
2024-11-16 |
美商再生元醫藥公司 |
用於生物巨分子分析之具質譜法的不對稱流場流分離
|
|
TW202446462A
(zh)
|
2023-02-22 |
2024-12-01 |
美商再生元醫藥公司 |
系統適用性參數及管柱老化
|
|
AU2024265540A1
(en)
|
2023-05-01 |
2025-10-30 |
Regeneron Pharmaceuticals, Inc. |
Multidose antibody drug products using phenol or benzyl alcohol
|
|
TW202528736A
(zh)
|
2023-09-08 |
2025-07-16 |
美商再生元醫藥公司 |
用於評估層析管柱完整性的方法及系統
|
|
US20250095773A1
(en)
|
2023-09-18 |
2025-03-20 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for developing chromatography protocols
|
|
TW202532098A
(zh)
|
2023-09-29 |
2025-08-16 |
美商再生元醫藥公司 |
使用控制成核之冷凍乾燥
|
|
WO2025085594A1
(en)
|
2023-10-18 |
2025-04-24 |
Regeneron Pharmaceuticals, Inc. |
Rapid purification of monoclonal antibody from in-process upstream cell culture material
|
|
WO2025096932A1
(en)
|
2023-11-02 |
2025-05-08 |
Regeneron Pharmaceuticals, Inc. |
Methods for reducing lipase activity using stress
|
|
WO2025166281A1
(en)
|
2024-02-01 |
2025-08-07 |
Regeneron Pharmaceuticals, Inc. |
Platform for charge-detection mass spectrometry analysis of aavs
|
|
WO2025175164A1
(en)
|
2024-02-16 |
2025-08-21 |
Regeneron Pharmaceuticals, Inc. |
Methods of producing concentrated formulated drug substances comprising proteins, and concentrated formulated drug substance made by the methods
|
|
WO2025194043A1
(en)
|
2024-03-15 |
2025-09-18 |
Regeneron Pharmaceuticals, Inc. |
Polysorbate and polyoxyethylene sorbitan as excipients for stable protein formulations
|
|
CN118440214B
(zh)
*
|
2024-04-02 |
2025-01-28 |
山东大学 |
一种靶向PDGFRβ的嵌合抗原受体、CAR-T细胞及应用
|
|
WO2025259840A1
(en)
|
2024-06-13 |
2025-12-18 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for scaled chromatography
|