JP2016502989A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016502989A5 JP2016502989A5 JP2015547016A JP2015547016A JP2016502989A5 JP 2016502989 A5 JP2016502989 A5 JP 2016502989A5 JP 2015547016 A JP2015547016 A JP 2015547016A JP 2015547016 A JP2015547016 A JP 2015547016A JP 2016502989 A5 JP2016502989 A5 JP 2016502989A5
- Authority
- JP
- Japan
- Prior art keywords
- buprenorphine
- transdermal therapeutic
- therapeutic system
- hours
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229960001736 buprenorphine Drugs 0.000 claims 103
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 claims 102
- 230000001225 therapeutic effect Effects 0.000 claims 76
- 239000010410 layer Substances 0.000 claims 36
- 150000003839 salts Chemical class 0.000 claims 23
- 239000011159 matrix material Substances 0.000 claims 22
- 229920000642 polymer Polymers 0.000 claims 15
- 239000012790 adhesive layer Substances 0.000 claims 13
- JOOXCMJARBKPKM-UHFFFAOYSA-N 4-oxopentanoic acid Chemical compound CC(=O)CCC(O)=O JOOXCMJARBKPKM-UHFFFAOYSA-N 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 12
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims 10
- 239000011248 coating agent Substances 0.000 claims 6
- 238000000576 coating method Methods 0.000 claims 6
- 229940040102 levulinic acid Drugs 0.000 claims 6
- 150000001735 carboxylic acids Chemical class 0.000 claims 5
- -1 buprenorphine carboxylate Chemical class 0.000 claims 4
- 239000000853 adhesive Substances 0.000 claims 3
- 230000001070 adhesive effect Effects 0.000 claims 3
- 230000001186 cumulative effect Effects 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 claims 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims 2
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims 2
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims 2
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims 2
- 239000005642 Oleic acid Substances 0.000 claims 2
- 239000011149 active material Substances 0.000 claims 2
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims 2
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims 2
- 238000009792 diffusion process Methods 0.000 claims 2
- 238000001035 drying Methods 0.000 claims 2
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims 2
- 238000010030 laminating Methods 0.000 claims 2
- 229960004488 linolenic acid Drugs 0.000 claims 2
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 claims 2
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims 2
- 229920000058 polyacrylate Polymers 0.000 claims 2
- 229920001296 polysiloxane Polymers 0.000 claims 2
- 229920002367 Polyisobutene Polymers 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 229940100640 transdermal system Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261736342P | 2012-12-12 | 2012-12-12 | |
| US61/736,342 | 2012-12-12 | ||
| PCT/EP2013/076325 WO2014090921A1 (en) | 2012-12-12 | 2013-12-12 | Transdermal delivery system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016502989A JP2016502989A (ja) | 2016-02-01 |
| JP2016502989A5 true JP2016502989A5 (enExample) | 2017-01-19 |
Family
ID=49816915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015547016A Abandoned JP2016502989A (ja) | 2012-12-12 | 2013-12-12 | 経皮送達システム |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US20150306093A1 (enExample) |
| EP (1) | EP2931263A1 (enExample) |
| JP (1) | JP2016502989A (enExample) |
| KR (1) | KR20150096460A (enExample) |
| CN (1) | CN105007906A (enExample) |
| AP (1) | AP2015008525A0 (enExample) |
| AR (1) | AR093940A1 (enExample) |
| AU (1) | AU2013205080B2 (enExample) |
| BR (1) | BR112015013660A2 (enExample) |
| CA (1) | CA2894960A1 (enExample) |
| CL (1) | CL2015001577A1 (enExample) |
| CR (1) | CR20150360A (enExample) |
| DE (1) | DE112013005945T5 (enExample) |
| EA (1) | EA201591124A1 (enExample) |
| GB (1) | GB2523715A (enExample) |
| HK (1) | HK1215677A1 (enExample) |
| IL (1) | IL239223A0 (enExample) |
| MX (1) | MX2015007348A (enExample) |
| NZ (1) | NZ628092A (enExample) |
| PE (1) | PE20151147A1 (enExample) |
| PH (1) | PH12015501169A1 (enExample) |
| SG (1) | SG11201504286VA (enExample) |
| TN (1) | TN2015000201A1 (enExample) |
| TW (1) | TW201438765A (enExample) |
| WO (1) | WO2014090921A1 (enExample) |
| ZA (1) | ZA201504964B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006054731B4 (de) | 2006-11-21 | 2013-02-28 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie |
| EP2790685B1 (en) | 2011-12-12 | 2017-08-16 | LTS LOHMANN Therapie-Systeme AG | Transdermal delivery system comprising buprenorphine |
| LT2810646T (lt) | 2013-06-04 | 2016-10-25 | Lts Lohmann Therapie-Systeme Ag | Transderminė tiekimo sistema |
| SG11201707350TA (en) | 2015-03-10 | 2017-10-30 | Rhodes Tech | Acetate salt of buprenorphine and methods for preparing buprenorphine |
| EP3349737A4 (en) * | 2015-09-14 | 2019-05-15 | Amneal Pharmaceuticals LLC | SYSTEM FOR TRANSDERING |
| KR101695603B1 (ko) * | 2016-11-08 | 2017-01-12 | 이창우 | 병목 하단 밀착 구조의 점탄성 연결캡을 포함하는 니들 디스크 롤러 장치 |
| WO2019064026A1 (en) | 2017-09-29 | 2019-04-04 | Orexo Ab | NEW PHARMACEUTICAL COMPOSITIONS |
| BR112020018607A2 (pt) * | 2018-03-13 | 2020-12-29 | Lts Lohmann Therapie-Systeme Ag | Sistema terapêutico transdérmico compreendendo um polímero híbrido de silicone acrílico |
| CA3092750A1 (en) * | 2018-03-13 | 2019-09-19 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system for the transdermal administration of buprenorphine comprising a silicone acrylic hybrid polymer |
| WO2019175106A1 (en) * | 2018-03-13 | 2019-09-19 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system comprising a silicone acrylic hybrid polymer |
| BR112020018300A2 (pt) * | 2018-03-13 | 2020-12-22 | Lts Lohmann Therapie-Systeme Ag | Sistema terapêutico transdérmico compreendendo um polímero híbrido de silicone e acrílico |
| GB201904767D0 (en) | 2019-04-04 | 2019-05-22 | Orexo Ab | New pharmaceutical compositions |
| CN114025748A (zh) * | 2019-07-09 | 2022-02-08 | 罗曼治疗系统股份公司 | 包括包含含硅酮聚合物的含活性剂层和包含硅酮凝胶粘合剂的皮肤接触层的透皮治疗系统 |
| CN113952319A (zh) * | 2021-11-30 | 2022-01-21 | 烟台大学 | 一种含丁丙诺啡的骨架型透皮贴剂及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968547A (en) * | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US7270830B2 (en) * | 2002-12-13 | 2007-09-18 | Purdue Pharma L.P. | Transdermal buprenorphine dosage regimen for analgesia |
| CN1943576A (zh) * | 2006-10-27 | 2007-04-11 | 哈尔滨健迪医药技术有限公司 | 丁丙诺啡和/或盐酸丁丙诺啡贴剂基质及其贴剂的制备方法 |
| DE102006054731B4 (de) * | 2006-11-21 | 2013-02-28 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie |
| CN101612141B (zh) * | 2009-07-29 | 2012-10-03 | 考司美德制药株式会社 | 丁丙诺啡贴剂 |
-
2013
- 2013-04-13 AU AU2013205080A patent/AU2013205080B2/en not_active Ceased
- 2013-12-12 DE DE112013005945.2T patent/DE112013005945T5/de not_active Withdrawn
- 2013-12-12 AP AP2015008525A patent/AP2015008525A0/xx unknown
- 2013-12-12 HK HK16103661.4A patent/HK1215677A1/zh unknown
- 2013-12-12 BR BR112015013660A patent/BR112015013660A2/pt active Search and Examination
- 2013-12-12 AR ARP130104652A patent/AR093940A1/es unknown
- 2013-12-12 NZ NZ628092A patent/NZ628092A/en not_active IP Right Cessation
- 2013-12-12 CN CN201380071638.8A patent/CN105007906A/zh active Pending
- 2013-12-12 SG SG11201504286VA patent/SG11201504286VA/en unknown
- 2013-12-12 WO PCT/EP2013/076325 patent/WO2014090921A1/en not_active Ceased
- 2013-12-12 TW TW102145867A patent/TW201438765A/zh unknown
- 2013-12-12 EA EA201591124A patent/EA201591124A1/ru unknown
- 2013-12-12 GB GB1512243.5A patent/GB2523715A/en not_active Withdrawn
- 2013-12-12 US US14/650,451 patent/US20150306093A1/en not_active Abandoned
- 2013-12-12 JP JP2015547016A patent/JP2016502989A/ja not_active Abandoned
- 2013-12-12 PE PE2015000906A patent/PE20151147A1/es not_active Application Discontinuation
- 2013-12-12 KR KR1020157018513A patent/KR20150096460A/ko not_active Withdrawn
- 2013-12-12 CA CA2894960A patent/CA2894960A1/en not_active Abandoned
- 2013-12-12 EP EP13810924.4A patent/EP2931263A1/en not_active Withdrawn
- 2013-12-12 MX MX2015007348A patent/MX2015007348A/es unknown
-
2015
- 2015-05-22 TN TNP2015000201A patent/TN2015000201A1/fr unknown
- 2015-05-26 PH PH12015501169A patent/PH12015501169A1/en unknown
- 2015-06-04 IL IL239223A patent/IL239223A0/en unknown
- 2015-06-08 CL CL2015001577A patent/CL2015001577A1/es unknown
- 2015-07-09 CR CR20150360A patent/CR20150360A/es unknown
- 2015-07-10 ZA ZA2015/04964A patent/ZA201504964B/en unknown
-
2018
- 2018-03-08 US US15/915,369 patent/US20180193333A1/en not_active Abandoned
-
2020
- 2020-04-30 US US16/863,584 patent/US20200253957A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016502989A5 (enExample) | ||
| JP2016520638A5 (enExample) | ||
| JP2015500329A5 (enExample) | ||
| JP6109280B2 (ja) | 活性物質の利用率及び用量精度の高い経皮治療システム | |
| KR101853082B1 (ko) | 활성제층 및 활성제 변환층을 포함하는 경피 조성물 | |
| JP5591685B2 (ja) | 経皮吸収製剤 | |
| JP4628673B2 (ja) | 活性成分フェンタニルを含む経皮治療システム（ｔｔｓ） | |
| US20090291127A1 (en) | Transdermal anti-dementia active agent formulations and methods for using the same | |
| JPH09505028A (ja) | 経皮的／経頬的にニコチン置換治療を提供する方法およびデバイス | |
| US20180256562A1 (en) | Transdermal Delivery System | |
| JP2010510260A5 (enExample) | ||
| WO2003037393A1 (en) | Plaster having laminated support | |
| RU2014125322A (ru) | Средство и способ трансдермальной доставки эстрогена | |
| EP3160461A1 (en) | Transdermal delivery system | |
| TWI415636B (zh) | Bisoprolol transdermal device | |
| JP4809062B2 (ja) | カバー材及びカバー材付き貼付剤 | |
| EP2914249B1 (en) | Propynylaminoindan transdermal compositions | |
| JP5027373B2 (ja) | エストラジオール含有貼付剤 | |
| KR101353478B1 (ko) | 펜타닐을 함유하는 경피투여용 패취 제제 | |
| JP2018535225A (ja) | 経皮薬剤送達のためのシステムおよび方法 | |
| JP2017190309A (ja) | リバスチグミン経皮吸収製剤 | |
| CA3236288A1 (en) | Occlusive plaster with flexible backing | |
| JP2004075538A (ja) | ノルエチステロン含有外用貼付剤 | |
| HK1069534B (en) | Transdermal therapeutic system (tts) with fentanyl as active ingredient |