DE112013005945T5 - Transdermales Verabreichungssystem - Google Patents

Transdermales Verabreichungssystem Download PDF

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Publication number
DE112013005945T5
DE112013005945T5 DE112013005945.2T DE112013005945T DE112013005945T5 DE 112013005945 T5 DE112013005945 T5 DE 112013005945T5 DE 112013005945 T DE112013005945 T DE 112013005945T DE 112013005945 T5 DE112013005945 T5 DE 112013005945T5
Authority
DE
Germany
Prior art keywords
buprenorphine
transdermal therapeutic
therapeutic system
base
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE112013005945.2T
Other languages
German (de)
English (en)
Inventor
Thomas Hille
Gabriel Wauer
Kevin John Smith
Gillian Elizabeth Mundin
Helen Elizabeth Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49816915&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE112013005945(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Publication of DE112013005945T5 publication Critical patent/DE112013005945T5/de
Withdrawn legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE112013005945.2T 2012-12-12 2013-12-12 Transdermales Verabreichungssystem Withdrawn DE112013005945T5 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261736342P 2012-12-12 2012-12-12
US61/736,342 2012-12-12
PCT/EP2013/076325 WO2014090921A1 (en) 2012-12-12 2013-12-12 Transdermal delivery system

Publications (1)

Publication Number Publication Date
DE112013005945T5 true DE112013005945T5 (de) 2015-08-27

Family

ID=49816915

Family Applications (1)

Application Number Title Priority Date Filing Date
DE112013005945.2T Withdrawn DE112013005945T5 (de) 2012-12-12 2013-12-12 Transdermales Verabreichungssystem

Country Status (26)

Country Link
US (3) US20150306093A1 (enExample)
EP (1) EP2931263A1 (enExample)
JP (1) JP2016502989A (enExample)
KR (1) KR20150096460A (enExample)
CN (1) CN105007906A (enExample)
AP (1) AP2015008525A0 (enExample)
AR (1) AR093940A1 (enExample)
AU (1) AU2013205080B2 (enExample)
BR (1) BR112015013660A2 (enExample)
CA (1) CA2894960A1 (enExample)
CL (1) CL2015001577A1 (enExample)
CR (1) CR20150360A (enExample)
DE (1) DE112013005945T5 (enExample)
EA (1) EA201591124A1 (enExample)
GB (1) GB2523715A (enExample)
HK (1) HK1215677A1 (enExample)
IL (1) IL239223A0 (enExample)
MX (1) MX2015007348A (enExample)
NZ (1) NZ628092A (enExample)
PE (1) PE20151147A1 (enExample)
PH (1) PH12015501169A1 (enExample)
SG (1) SG11201504286VA (enExample)
TN (1) TN2015000201A1 (enExample)
TW (1) TW201438765A (enExample)
WO (1) WO2014090921A1 (enExample)
ZA (1) ZA201504964B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006054731B4 (de) 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
AU2012327247B2 (en) 2011-12-12 2015-12-24 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system
DE112014002664T5 (de) 2013-06-04 2016-04-07 Lts Lohmann Therapie-Systeme Ag Transdermales Verabreichungssystem
CA3104099A1 (en) 2015-03-10 2016-09-15 Rhodes Technologies Acetate salt of buprenorphine and methods for preparing buprenorphine
WO2017048595A1 (en) * 2015-09-14 2017-03-23 Amneal Pharmaceuticals Llc Transdermal delivery system
KR101695603B1 (ko) * 2016-11-08 2017-01-12 이창우 병목 하단 밀착 구조의 점탄성 연결캡을 포함하는 니들 디스크 롤러 장치
WO2019064026A1 (en) 2017-09-29 2019-04-04 Orexo Ab NEW PHARMACEUTICAL COMPOSITIONS
US20210008000A1 (en) * 2018-03-13 2021-01-14 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system comprising a silicone acrylic hybrid polymer
CN111971032A (zh) * 2018-03-13 2020-11-20 罗曼治疗系统股份公司 包含有机硅丙烯酸杂化聚合物的透皮治疗系统
WO2019175101A1 (en) * 2018-03-13 2019-09-19 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system comprising a silicone acrylic hybrid polymer
US20210000755A1 (en) * 2018-03-13 2021-01-07 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system for the transdermal administration of buprenorphine comprising a silicone acrylic hybrid polymer
GB201904767D0 (en) 2019-04-04 2019-05-22 Orexo Ab New pharmaceutical compositions
US20220241215A1 (en) * 2019-07-09 2022-08-04 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system comprising an active agent-containing layer comprising a silicone-containing polymer and a skin contact layer comprising a silicone gel adhesive
CN113952319A (zh) * 2021-11-30 2022-01-21 烟台大学 一种含丁丙诺啡的骨架型透皮贴剂及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968547A (en) * 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
JP5054893B2 (ja) * 2002-12-13 2012-10-24 ユーロ−セルティーク エス.エイ. 鎮痛のためのブプレノルフィン経皮投与計画
CN1943576A (zh) * 2006-10-27 2007-04-11 哈尔滨健迪医药技术有限公司 丁丙诺啡和/或盐酸丁丙诺啡贴剂基质及其贴剂的制备方法
DE102006054731B4 (de) * 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
CN101612141B (zh) * 2009-07-29 2012-10-03 考司美德制药株式会社 丁丙诺啡贴剂

Also Published As

Publication number Publication date
CN105007906A (zh) 2015-10-28
SG11201504286VA (en) 2015-06-29
BR112015013660A2 (pt) 2017-07-11
AU2013205080B2 (en) 2016-07-07
EP2931263A1 (en) 2015-10-21
NZ628092A (en) 2017-01-27
GB201512243D0 (en) 2015-08-19
TN2015000201A1 (en) 2016-10-03
US20150306093A1 (en) 2015-10-29
US20200253957A1 (en) 2020-08-13
HK1215677A1 (zh) 2016-09-09
AR093940A1 (es) 2015-07-01
PH12015501169A1 (en) 2015-08-10
GB2523715A (en) 2015-09-02
CR20150360A (es) 2015-08-21
ZA201504964B (en) 2017-11-29
PE20151147A1 (es) 2015-08-06
JP2016502989A (ja) 2016-02-01
TW201438765A (zh) 2014-10-16
AP2015008525A0 (en) 2015-06-30
IL239223A0 (en) 2015-07-30
AU2013205080A1 (en) 2014-06-26
WO2014090921A1 (en) 2014-06-19
EA201591124A1 (ru) 2015-11-30
CL2015001577A1 (es) 2015-10-02
KR20150096460A (ko) 2015-08-24
MX2015007348A (es) 2016-01-20
US20180193333A1 (en) 2018-07-12
CA2894960A1 (en) 2014-06-19

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R082 Change of representative

Representative=s name: MAIWALD PATENTANWALTS- UND RECHTSANWALTSGESELL, DE

R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee