TN2015000201A1 - Transdermal delivery system - Google Patents

Transdermal delivery system

Info

Publication number
TN2015000201A1
TN2015000201A1 TNP2015000201A TN2015000201A TN2015000201A1 TN 2015000201 A1 TN2015000201 A1 TN 2015000201A1 TN P2015000201 A TNP2015000201 A TN P2015000201A TN 2015000201 A TN2015000201 A TN 2015000201A TN 2015000201 A1 TN2015000201 A1 TN 2015000201A1
Authority
TN
Tunisia
Prior art keywords
buprenorphine
layer
acid
patient
matrix layer
Prior art date
Application number
TNP2015000201A
Other languages
English (en)
Inventor
Gabriel Wauer
Kevin John Smith
Gillian Elizabeth Mundin
Helen Elizabeth Johnson
Thomas Hille
Original Assignee
Lts Lohmann Therapie Systeme Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49816915&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TN2015000201(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lts Lohmann Therapie Systeme Ag filed Critical Lts Lohmann Therapie Systeme Ag
Publication of TN2015000201A1 publication Critical patent/TN2015000201A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TNP2015000201A 2012-12-12 2015-05-22 Transdermal delivery system TN2015000201A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261736342P 2012-12-12 2012-12-12
PCT/EP2013/076325 WO2014090921A1 (fr) 2012-12-12 2013-12-12 Système d'administration transdermique

Publications (1)

Publication Number Publication Date
TN2015000201A1 true TN2015000201A1 (en) 2016-10-03

Family

ID=49816915

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2015000201A TN2015000201A1 (en) 2012-12-12 2015-05-22 Transdermal delivery system

Country Status (26)

Country Link
US (3) US20150306093A1 (fr)
EP (1) EP2931263A1 (fr)
JP (1) JP2016502989A (fr)
KR (1) KR20150096460A (fr)
CN (1) CN105007906A (fr)
AP (1) AP2015008525A0 (fr)
AR (1) AR093940A1 (fr)
AU (1) AU2013205080B2 (fr)
BR (1) BR112015013660A2 (fr)
CA (1) CA2894960A1 (fr)
CL (1) CL2015001577A1 (fr)
CR (1) CR20150360A (fr)
DE (1) DE112013005945T5 (fr)
EA (1) EA201591124A1 (fr)
GB (1) GB2523715A (fr)
HK (1) HK1215677A1 (fr)
IL (1) IL239223A0 (fr)
MX (1) MX2015007348A (fr)
NZ (1) NZ628092A (fr)
PE (1) PE20151147A1 (fr)
PH (1) PH12015501169A1 (fr)
SG (1) SG11201504286VA (fr)
TN (1) TN2015000201A1 (fr)
TW (1) TW201438765A (fr)
WO (1) WO2014090921A1 (fr)
ZA (1) ZA201504964B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006054731B4 (de) 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
EA201491164A1 (ru) 2011-12-12 2014-10-30 ЭлТиЭс ЛОМАНН ТЕРАПИ-ЗЮСТЕМ АГ Трансдермальная система доставки
WO2014195352A1 (fr) 2013-06-04 2014-12-11 Lts Lohmann Therapie-Systeme Ag Système d'administration transdermique
US10406152B2 (en) 2015-03-10 2019-09-10 Rhodes Technologies Acetate salt of buprenorphine and methods for preparing buprenorphine
EP3349737A4 (fr) * 2015-09-14 2019-05-15 Amneal Pharmaceuticals LLC Système d'administration transdermique
KR101695603B1 (ko) * 2016-11-08 2017-01-12 이창우 병목 하단 밀착 구조의 점탄성 연결캡을 포함하는 니들 디스크 롤러 장치
WO2019064026A1 (fr) 2017-09-29 2019-04-04 Orexo Ab Nouvelles compositions pharmaceutiques
WO2019175096A1 (fr) * 2018-03-13 2019-09-19 Lts Lohmann Therapie-Systeme Ag Système thérapeutique transdermique pour l'administration transdermique de buprénorphine comprenant un polymère hybride silicone-acrylique
JP2021515789A (ja) * 2018-03-13 2021-06-24 エルテーエス ローマン テラピー−ジステーメ アーゲー シリコーンアクリルハイブリッドポリマーを含む経皮治療システム
CN111971033A (zh) * 2018-03-13 2020-11-20 罗曼治疗系统股份公司 包含有机硅丙烯酸杂化聚合物的透皮治疗系统
US20210038532A1 (en) * 2018-03-13 2021-02-11 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system comprising a silicone acrylic hybrid polymer
GB201904767D0 (en) 2019-04-04 2019-05-22 Orexo Ab New pharmaceutical compositions
WO2021005117A1 (fr) * 2019-07-09 2021-01-14 Lts Lohmann Therapie-Systeme Ag Système thérapeutique transdermique comprenant une couche contenant un principe actif comprenant un polymère contenant de la silicone et une couche de contact avec la peau comprenant un adhésif à base de gel de silicone
CN113952319A (zh) * 2021-11-30 2022-01-21 烟台大学 一种含丁丙诺啡的骨架型透皮贴剂及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968547A (en) * 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
EP1572167B1 (fr) * 2002-12-13 2008-07-09 Euro-Celtique S.A. Regime posologique de buprenorphine transdermique pour l'analgesie
CN1943576A (zh) * 2006-10-27 2007-04-11 哈尔滨健迪医药技术有限公司 丁丙诺啡和/或盐酸丁丙诺啡贴剂基质及其贴剂的制备方法
DE102006054731B4 (de) * 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
CN101612141B (zh) * 2009-07-29 2012-10-03 考司美德制药株式会社 丁丙诺啡贴剂

Also Published As

Publication number Publication date
IL239223A0 (en) 2015-07-30
AP2015008525A0 (en) 2015-06-30
CN105007906A (zh) 2015-10-28
US20180193333A1 (en) 2018-07-12
AU2013205080B2 (en) 2016-07-07
WO2014090921A1 (fr) 2014-06-19
US20200253957A1 (en) 2020-08-13
EP2931263A1 (fr) 2015-10-21
HK1215677A1 (zh) 2016-09-09
DE112013005945T5 (de) 2015-08-27
GB2523715A (en) 2015-09-02
PE20151147A1 (es) 2015-08-06
TW201438765A (zh) 2014-10-16
GB201512243D0 (en) 2015-08-19
AU2013205080A1 (en) 2014-06-26
AR093940A1 (es) 2015-07-01
PH12015501169A1 (en) 2015-08-10
MX2015007348A (es) 2016-01-20
BR112015013660A2 (pt) 2017-07-11
NZ628092A (en) 2017-01-27
CR20150360A (es) 2015-08-21
ZA201504964B (en) 2017-11-29
EA201591124A1 (ru) 2015-11-30
US20150306093A1 (en) 2015-10-29
KR20150096460A (ko) 2015-08-24
JP2016502989A (ja) 2016-02-01
CL2015001577A1 (es) 2015-10-02
CA2894960A1 (fr) 2014-06-19
SG11201504286VA (en) 2015-06-29

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