JP2016501866A - 皮下脂肪生成を刺激するペプチド - Google Patents
皮下脂肪生成を刺激するペプチド Download PDFInfo
- Publication number
- JP2016501866A JP2016501866A JP2015544173A JP2015544173A JP2016501866A JP 2016501866 A JP2016501866 A JP 2016501866A JP 2015544173 A JP2015544173 A JP 2015544173A JP 2015544173 A JP2015544173 A JP 2015544173A JP 2016501866 A JP2016501866 A JP 2016501866A
- Authority
- JP
- Japan
- Prior art keywords
- seq
- peptide
- amino acid
- composition
- amino acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/001—Preparations for care of the lips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Birds (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261729626P | 2012-11-25 | 2012-11-25 | |
| US61/729,626 | 2012-11-25 | ||
| US201361778084P | 2013-03-12 | 2013-03-12 | |
| US61/778,084 | 2013-03-12 | ||
| PCT/US2013/071719 WO2014082042A2 (en) | 2012-11-25 | 2013-11-25 | Peptides that stimulate subcutaneous adipogenesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016501866A true JP2016501866A (ja) | 2016-01-21 |
| JP2016501866A5 JP2016501866A5 (enExample) | 2017-01-12 |
Family
ID=49753509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015544173A Pending JP2016501866A (ja) | 2012-11-25 | 2013-11-25 | 皮下脂肪生成を刺激するペプチド |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10766927B2 (enExample) |
| EP (1) | EP2922869B1 (enExample) |
| JP (1) | JP2016501866A (enExample) |
| KR (1) | KR20150088841A (enExample) |
| CN (1) | CN105008396A (enExample) |
| AU (1) | AU2013347797A1 (enExample) |
| CA (1) | CA2930117A1 (enExample) |
| HK (1) | HK1216895A1 (enExample) |
| IL (1) | IL239008A0 (enExample) |
| RU (1) | RU2015123315A (enExample) |
| WO (1) | WO2014082042A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1216895A1 (zh) | 2012-11-25 | 2016-12-09 | The Regents Of The University Of California | 刺激皮下脂肪形成的肽 |
| WO2015184125A1 (en) | 2014-05-28 | 2015-12-03 | The Regents Of The University Of California | Peptides, compositions, and methods for stimulating subcutaneous adipogenesis |
| US10562935B2 (en) | 2015-03-20 | 2020-02-18 | London Health Sciences Centre Research Inc. | Stapled peptides and uses thereof |
| CN107771085B (zh) * | 2015-04-17 | 2024-09-03 | 斯米克控股(美国)有限公司 | 生物缀合物及其用途 |
| KR102208853B1 (ko) * | 2018-05-08 | 2021-01-28 | 오션펩 주식회사 | 주름개선 효능을 갖는 펩티드 |
| CN113164512A (zh) * | 2018-11-26 | 2021-07-23 | 韩国海洋科学技术院 | 刺激脂肪生成的肽、组合物和方法 |
| CN114081861B (zh) * | 2021-11-19 | 2023-10-31 | 和泓尚医(成都)生物科技有限公司 | 一种干细胞外泌体与复合肽抗衰制剂及其制备方法和应用 |
| GB202211043D0 (en) * | 2022-07-28 | 2022-09-14 | Univ Birmingham | Peptide agonist |
| WO2025059165A1 (en) * | 2023-09-14 | 2025-03-20 | University Of Florida Research Foundation, Incorporated | Methods of use for rhamm-derived peptides and rhamm-derived peptide mimetics |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000512484A (ja) * | 1996-04-10 | 2000-09-26 | ユニヴァーシティ・オヴ・マニトバ | ヒト・ヒアルロナン・レセプター |
| US20040037834A1 (en) * | 2000-04-20 | 2004-02-26 | Woloski B. Michael R. | Rhamm peptide conjugates |
| JP2004536819A (ja) * | 2001-06-11 | 2004-12-09 | トランジション・セラピューティックス・インコーポレーテッド | ウイルス性、増殖性および炎症性の疾患の治療のためにビタミンb12および治療薬を用いた複合治療 |
| US20100143382A1 (en) * | 2006-11-21 | 2010-06-10 | Turley Eva A | Modulation of rhamm (cd168) for selective adipose tissue development |
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| CA175473A (en) * | 1917-01-08 | 1917-03-06 | Clarence G. Cashman | Reamer head |
| GB9207949D0 (en) | 1992-04-09 | 1992-05-27 | Univ Manitoba | Molecular cloning of a novel hyaluronan receptor that mediates tumor cell motility |
| WO1994016328A1 (en) | 1992-12-30 | 1994-07-21 | Matthias Rath | Synthetic oligopeptides analogous to protein signal sequences methods of identification and methods of use |
| GB9420740D0 (en) | 1994-10-14 | 1994-11-30 | Univ Manitoba | Sequence of the hyaluronan receptor gene |
| US6127525A (en) | 1995-02-21 | 2000-10-03 | Cornell Research Foundation, Inc. | Chimeric adenoviral coat protein and methods of using same |
| CA2166155C (en) | 1995-12-27 | 2008-02-05 | Eva Anne Turley | Agents binding to hyaluronic acid binding domains and the use thereof |
| US5827740A (en) | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
| CA2237051A1 (en) | 1997-12-19 | 1999-06-19 | Eva A. Turley | Enhanced affinity hyaluronan binding peptides |
| US6211149B1 (en) | 1998-08-03 | 2001-04-03 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibitors of formation of protease resistant prion protein |
| GB9811962D0 (en) | 1998-06-03 | 1998-07-29 | Janssen Pharmaceutica Nv | Vertebrate homologue of UNC-53 protein of C.elegans |
| EP1151012A4 (en) | 1998-11-19 | 2003-01-08 | Smithkline Beecham Corp | ANTAGONIST ANTIBODIES OF RHAMM |
| US6153432A (en) | 1999-01-29 | 2000-11-28 | Zen-Bio, Inc | Methods for the differentiation of human preadipocytes into adipocytes |
| JP2000217576A (ja) | 1999-02-02 | 2000-08-08 | Herikkusu Kenkyusho:Kk | 脂肪細胞への分化を誘導する方法、並びに脂肪細胞への分化を制御する化合物およびそのスクリーニング方法 |
| US6864235B1 (en) | 1999-04-01 | 2005-03-08 | Eva A. Turley | Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans |
| US6911429B2 (en) | 1999-04-01 | 2005-06-28 | Transition Therapeutics Inc. | Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans |
| US20070116669A1 (en) * | 2002-09-13 | 2007-05-24 | Chemokine Therapeutics Corporation | Interferon-inducible protein-10 (IP-10 or CXCL10) chemokine analogs for the treatment of human diseases |
| US7601825B2 (en) | 2001-03-05 | 2009-10-13 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 121P1F1 useful in treatment and detection of cancer |
| EP1407039A4 (en) * | 2001-06-19 | 2005-12-21 | Us Gov Health & Human Serv | ANTI-ARTHROPODE VECTOR VACCINES, SELECTION METHOD AND USES THEREOF |
| US7387800B2 (en) | 2001-08-15 | 2008-06-17 | Meiji Dairies Corporation | Sesquiterpenoid derivatives having adipocyte differentiation inhibitory effect |
| US20030170755A1 (en) | 2001-09-26 | 2003-09-11 | Ludwig Institute For Cancer Research | Tumor-associated antigen RHAMM |
| AU2002332028A1 (en) | 2001-10-06 | 2003-04-22 | Boston Medical Center Corporation | Preadipocyte cell strains and uses therefore |
| WO2003043998A1 (en) | 2001-11-15 | 2003-05-30 | Incyte San Diego Incorporated | N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders, cancer, and other diseases |
| WO2003048358A1 (fr) | 2001-12-07 | 2003-06-12 | Nissui Pharmaceutical Co., Ltd. | Gene et proteine associes a la differenciation adipocytaire |
| FR2834996B1 (fr) | 2002-01-18 | 2004-12-03 | Genfit S A | Methode d'identification de substances capables de moduler la differenciation adipocytaire |
| US7196108B2 (en) | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
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| AU2003259285A1 (en) | 2002-07-29 | 2004-02-16 | Hmgene, Inc. | Methods of identifying adipocyte specific genes, the genes identified, and their uses |
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| AU2004266642A1 (en) | 2003-08-12 | 2005-03-03 | University Of Utah Research Foundation | Heparin binding proteins: sensors for heparin detection |
| EP1677735B1 (en) | 2003-10-17 | 2014-07-23 | Joslin Diabetes Center, Inc. | Methods and compositions for modulating adipocyte function |
| US7544661B2 (en) | 2003-12-05 | 2009-06-09 | Northwestern University | Self-assembling peptide amphiphiles and related methods for growth factor delivery |
| CA2610791C (en) | 2005-06-08 | 2015-12-01 | Cangene Corporation | Hyaluronic acid binding peptides enhance host defense against pathogenic bacteria |
| US20090176306A1 (en) | 2005-06-10 | 2009-07-09 | Toshio Taira | Method of inducing differentiation from visceral preadipocyte to visceral adipocyte |
| US20070179085A1 (en) | 2005-07-20 | 2007-08-02 | Savani Rashmin C | Modulation of rhamm-caveolin/lipid raft interactions to affect development, responses to tissue injury, angiogenesis, tumorigenesis, metastasis and growth factor/cytokine responses |
| US20070292869A1 (en) | 2006-03-02 | 2007-12-20 | Ppd Biomarker Discovery Sciences, Llc | Compositions and Methods for Analyzing Renal Cancer |
| US8066691B2 (en) | 2006-04-21 | 2011-11-29 | Khouri Roger K | Method and system for preparing soft tissue for grafting, enhancing grafting results, and grafting autologous fat to soft tissue such as the breast |
| WO2008047061A2 (fr) | 2006-10-20 | 2008-04-24 | Laboratoires Inneov | Utilisation cosmetique par voie orale et/ou parenterale de la glucosamine eventuellement associee a au moins un compose polyphenol et composition correspondante |
| US20100062000A1 (en) | 2006-11-21 | 2010-03-11 | The Regents Of The University Of California | Rhamm, a Co-Receptor and Its Interactions with Other Receptors in Cancer Cell Motility and the Identification of Cancer Prognitor Cell Populations |
| EP1967524A1 (en) * | 2007-03-06 | 2008-09-10 | Friesland Brands B.V. | Methods for producing ACE-inhibitory peptides from whey and peptides obtained thereby |
| WO2009036246A2 (en) | 2007-09-14 | 2009-03-19 | Immunotope, Inc. | Immunogens that induce cytotoxic t-lymphocytes and their use in prevention, treatment, and diagnosis of cancer |
| EP2197908A2 (en) | 2007-09-27 | 2010-06-23 | Dako Denmark A/S | Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics |
| US20100290989A1 (en) | 2007-10-12 | 2010-11-18 | London Health Sciences Centre Research Inc. | Compositions affecting hyaluronic acid mediated activity |
| WO2009061130A2 (en) | 2007-11-06 | 2009-05-14 | Procell Therapeutics Inc. | Cell permeable runx3 recombinant proteins, polynucleotides encoding the same, and anticancer compositions including the same |
| US8216828B2 (en) | 2008-05-30 | 2012-07-10 | Corning Incorporated | Assembly of cell culture vessels |
| EP2576597A4 (en) | 2010-05-31 | 2013-11-06 | London Health Sci Ct Res Inc | HYALURONIC ACID MEDIATED MOTILITY RECEPTOR BINDING PEPTIDES (RHAMM) |
| US20120076810A1 (en) | 2010-09-01 | 2012-03-29 | Poland Gregory A | Vaccinia virus polypeptides |
| CA2809847A1 (en) | 2010-09-01 | 2012-03-08 | The Regents Of The University Of California | Cell culture screen for agents that control adipogenesis and myofibroblast differentiation |
| MX2013002303A (es) * | 2010-09-07 | 2013-10-28 | Oncotherapy Science Inc | Peptidos hjurp y vacunas que incluyen los mismos. |
| HK1216895A1 (zh) | 2012-11-25 | 2016-12-09 | The Regents Of The University Of California | 刺激皮下脂肪形成的肽 |
| WO2015184125A1 (en) | 2014-05-28 | 2015-12-03 | The Regents Of The University Of California | Peptides, compositions, and methods for stimulating subcutaneous adipogenesis |
-
2013
- 2013-11-25 HK HK16104706.9A patent/HK1216895A1/zh unknown
- 2013-11-25 KR KR1020157016698A patent/KR20150088841A/ko not_active Withdrawn
- 2013-11-25 WO PCT/US2013/071719 patent/WO2014082042A2/en not_active Ceased
- 2013-11-25 CN CN201380061413.4A patent/CN105008396A/zh active Pending
- 2013-11-25 EP EP13802811.3A patent/EP2922869B1/en not_active Not-in-force
- 2013-11-25 US US14/089,445 patent/US10766927B2/en not_active Expired - Fee Related
- 2013-11-25 AU AU2013347797A patent/AU2013347797A1/en not_active Abandoned
- 2013-11-25 JP JP2015544173A patent/JP2016501866A/ja active Pending
- 2013-11-25 RU RU2015123315A patent/RU2015123315A/ru not_active Application Discontinuation
- 2013-11-25 US US14/646,298 patent/US10494402B2/en active Active
- 2013-11-25 CA CA2930117A patent/CA2930117A1/en not_active Abandoned
-
2015
- 2015-05-25 IL IL239008A patent/IL239008A0/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000512484A (ja) * | 1996-04-10 | 2000-09-26 | ユニヴァーシティ・オヴ・マニトバ | ヒト・ヒアルロナン・レセプター |
| US20040037834A1 (en) * | 2000-04-20 | 2004-02-26 | Woloski B. Michael R. | Rhamm peptide conjugates |
| JP2004536819A (ja) * | 2001-06-11 | 2004-12-09 | トランジション・セラピューティックス・インコーポレーテッド | ウイルス性、増殖性および炎症性の疾患の治療のためにビタミンb12および治療薬を用いた複合治療 |
| US20100143382A1 (en) * | 2006-11-21 | 2010-06-10 | Turley Eva A | Modulation of rhamm (cd168) for selective adipose tissue development |
Non-Patent Citations (1)
| Title |
|---|
| JOURNAL OF CELL SCIENCE, vol. 111, no. 12, JPN6017029483, 1998, pages 1685 - 1694, ISSN: 0003778661 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014082042A2 (en) | 2014-05-30 |
| EP2922869B1 (en) | 2017-09-27 |
| AU2013347797A1 (en) | 2015-07-02 |
| KR20150088841A (ko) | 2015-08-03 |
| IL239008A0 (en) | 2015-07-30 |
| US20140179616A1 (en) | 2014-06-26 |
| US10494402B2 (en) | 2019-12-03 |
| US20150284433A1 (en) | 2015-10-08 |
| CA2930117A1 (en) | 2014-05-30 |
| CN105008396A (zh) | 2015-10-28 |
| US10766927B2 (en) | 2020-09-08 |
| EP2922869A2 (en) | 2015-09-30 |
| WO2014082042A3 (en) | 2014-07-24 |
| RU2015123315A (ru) | 2017-01-10 |
| HK1216895A1 (zh) | 2016-12-09 |
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Legal Events
| Date | Code | Title | Description |
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| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20161124 |
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