KR20150088841A - 피하 지방생성을 자극하는 펩타이드 - Google Patents

피하 지방생성을 자극하는 펩타이드 Download PDF

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Publication number
KR20150088841A
KR20150088841A KR1020157016698A KR20157016698A KR20150088841A KR 20150088841 A KR20150088841 A KR 20150088841A KR 1020157016698 A KR1020157016698 A KR 1020157016698A KR 20157016698 A KR20157016698 A KR 20157016698A KR 20150088841 A KR20150088841 A KR 20150088841A
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seq
peptide
amino acid
composition
amino acids
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KR1020157016698A
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Korean (ko)
Inventor
에바 에이 털리
세예드 바람 바라미
미나 제이 비셀
Original Assignee
더 리전트 오브 더 유니버시티 오브 캘리포니아
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Publication of KR20150088841A publication Critical patent/KR20150088841A/ko
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/03Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/001Preparations for care of the lips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Birds (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
KR1020157016698A 2012-11-25 2013-11-25 피하 지방생성을 자극하는 펩타이드 Withdrawn KR20150088841A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261729626P 2012-11-25 2012-11-25
US61/729,626 2012-11-25
US201361778084P 2013-03-12 2013-03-12
US61/778,084 2013-03-12
PCT/US2013/071719 WO2014082042A2 (en) 2012-11-25 2013-11-25 Peptides that stimulate subcutaneous adipogenesis

Publications (1)

Publication Number Publication Date
KR20150088841A true KR20150088841A (ko) 2015-08-03

Family

ID=49753509

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157016698A Withdrawn KR20150088841A (ko) 2012-11-25 2013-11-25 피하 지방생성을 자극하는 펩타이드

Country Status (11)

Country Link
US (2) US10494402B2 (enExample)
EP (1) EP2922869B1 (enExample)
JP (1) JP2016501866A (enExample)
KR (1) KR20150088841A (enExample)
CN (1) CN105008396A (enExample)
AU (1) AU2013347797A1 (enExample)
CA (1) CA2930117A1 (enExample)
HK (1) HK1216895A1 (enExample)
IL (1) IL239008A0 (enExample)
RU (1) RU2015123315A (enExample)
WO (1) WO2014082042A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190128603A (ko) * 2018-05-08 2019-11-18 경상대학교산학협력단 주름개선 효능을 갖는 펩티드
WO2020111743A1 (ko) * 2018-11-26 2020-06-04 한국해양과학기술원 지방 생성을 자극하는 펩타이드, 조성 및 방법

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2922869B1 (en) 2012-11-25 2017-09-27 The Regents of The University of California Peptides that stimulate subcutaneous adipogenesis
US10844102B2 (en) 2014-05-28 2020-11-24 The Regents Of The University Of California Peptides, compositions, and methods for stimulating subcutaneous adipogenesis
WO2016151478A1 (en) * 2015-03-20 2016-09-29 London Health Sciences Centre Research Inc. Stapled peptides and uses thereof
BR112017021970A2 (pt) * 2015-04-17 2018-07-10 Symic Ip Llc bioconjugados e usos dos mesmos
CN114081861B (zh) * 2021-11-19 2023-10-31 和泓尚医(成都)生物科技有限公司 一种干细胞外泌体与复合肽抗衰制剂及其制备方法和应用
GB202211043D0 (en) * 2022-07-28 2022-09-14 Univ Birmingham Peptide agonist
WO2025059165A1 (en) * 2023-09-14 2025-03-20 University Of Florida Research Foundation, Incorporated Methods of use for rhamm-derived peptides and rhamm-derived peptide mimetics

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA175473A (en) * 1917-01-08 1917-03-06 Clarence G. Cashman Reamer head
GB9207949D0 (en) 1992-04-09 1992-05-27 Univ Manitoba Molecular cloning of a novel hyaluronan receptor that mediates tumor cell motility
AU6081094A (en) 1992-12-30 1994-08-15 Matthias Rath Synthetic oligopeptides analogous to protein signal sequences methods of identification and methods of use
GB9420740D0 (en) 1994-10-14 1994-11-30 Univ Manitoba Sequence of the hyaluronan receptor gene
US6127525A (en) * 1995-02-21 2000-10-03 Cornell Research Foundation, Inc. Chimeric adenoviral coat protein and methods of using same
CA2166155C (en) 1995-12-27 2008-02-05 Eva Anne Turley Agents binding to hyaluronic acid binding domains and the use thereof
GB9607441D0 (en) 1996-04-10 1996-06-12 Univ Manitoba Human hyaluronan receptor
US5827740A (en) 1996-07-30 1998-10-27 Osiris Therapeutics, Inc. Adipogenic differentiation of human mesenchymal stem cells
CA2237051A1 (en) 1997-12-19 1999-06-19 Eva A. Turley Enhanced affinity hyaluronan binding peptides
US6211149B1 (en) * 1998-08-03 2001-04-03 The United States Of America As Represented By The Department Of Health And Human Services Inhibitors of formation of protease resistant prion protein
GB9811962D0 (en) 1998-06-03 1998-07-29 Janssen Pharmaceutica Nv Vertebrate homologue of UNC-53 protein of C.elegans
WO2000029447A1 (en) 1998-11-19 2000-05-25 Smithkline Beecham Corporation Rhamm antagonist antibodies
US6153432A (en) 1999-01-29 2000-11-28 Zen-Bio, Inc Methods for the differentiation of human preadipocytes into adipocytes
JP2000217576A (ja) 1999-02-02 2000-08-08 Herikkusu Kenkyusho:Kk 脂肪細胞への分化を誘導する方法、並びに脂肪細胞への分化を制御する化合物およびそのスクリーニング方法
US6864235B1 (en) 1999-04-01 2005-03-08 Eva A. Turley Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans
US6911429B2 (en) 1999-04-01 2005-06-28 Transition Therapeutics Inc. Compositions and methods for treating cellular response to injury and other proliferating cell disorders regulated by hyaladherin and hyaluronans
US20070116669A1 (en) * 2002-09-13 2007-05-24 Chemokine Therapeutics Corporation Interferon-inducible protein-10 (IP-10 or CXCL10) chemokine analogs for the treatment of human diseases
AU2001250212A1 (en) * 2000-04-20 2001-11-07 Cangene Corporation Rhamm peptide conjugates
US7601825B2 (en) 2001-03-05 2009-10-13 Agensys, Inc. Nucleic acid and corresponding protein entitled 121P1F1 useful in treatment and detection of cancer
WO2002100428A1 (en) 2001-06-11 2002-12-19 Transition Therapeutics Inc. Combination therapies using vitamin b12 and therapeutic agents for treatment of viral, proliferative and inflammatory diseases
US7388089B2 (en) * 2001-06-19 2008-06-17 The United States Of America As Represented By The Department Of Health And Human Services Anti-arthropod vector vaccines method of selecting and uses thereof
ATE345126T1 (de) 2001-08-15 2006-12-15 Meiji Dairies Corp Sesquiterpenoid-derivate mit adipozytendifferenzierungshemmender wirkung
US20030170755A1 (en) 2001-09-26 2003-09-11 Ludwig Institute For Cancer Research Tumor-associated antigen RHAMM
WO2003031640A2 (en) 2001-10-06 2003-04-17 Boston Medical Center Corporation Preadipocyte cell strains and uses therefore
EP1456187A4 (en) 2001-11-15 2005-02-09 Incyte San Diego Inc N-SUBSTITUTED HETEROCYCLES FOR THE TREATMENT OF HYPERCHOLESTERINEMIA, DYSLIPIDEMIA AND OTHER METABOLIC DISORDER, CANCER AND OTHER DISEASES
US7351551B2 (en) 2001-12-07 2008-04-01 Nissui Pharmaceutical Co., Ltd. Adipocyte differentiation-associated gene and protein
FR2834996B1 (fr) 2002-01-18 2004-12-03 Genfit S A Methode d'identification de substances capables de moduler la differenciation adipocytaire
US7196108B2 (en) 2002-03-08 2007-03-27 Incyte San Diego Inc. Bicyclic heterocycles for the treatment of diabetes and other diseases
SE0201863D0 (en) * 2002-06-18 2002-06-18 Cepep Ab Cell penetrating peptides
WO2004003545A1 (en) 2002-07-01 2004-01-08 Tufts University Methods and compositions for inhibition of multi-drug resistance by hyaluronan oligomers
US7879544B2 (en) 2002-07-29 2011-02-01 Hmgene Inc. Methods of identifying adipocyte specific genes, the genes identified, and their uses
WO2005032453A2 (en) * 2003-04-28 2005-04-14 Sequoia Pharmaceuticals, Inc. Antiviral agents for the treatment, control and prevention of infections by coronaviruses
US20040229219A1 (en) * 2003-04-30 2004-11-18 Gallaher William R. Method of inhibiting human metapneumovirus and human coronavirus in the prevention and treatment of severe acute respiratory syndrome (SARS)
EP1668359A2 (en) 2003-08-12 2006-06-14 University of Utah Research Foundation Heparin binding proteins: sensors for heparin detection
EP2441474B1 (en) 2003-10-17 2015-08-05 Joslin Diabetes Center, Inc. Methods and compositions for modulating adipocyte function
CN1905892A (zh) 2003-12-05 2007-01-31 西北大学 自组装的肽两亲物和用于生长因子传递的相关方法
JP5140579B2 (ja) 2005-06-08 2013-02-06 カンジェーン コーポレイション 病原菌に対する生体防御を増強するヒアルロン酸結合性ペプチド
JP5049794B2 (ja) 2005-06-10 2012-10-17 株式会社プライマリーセル 内臓前駆脂肪細胞から内臓脂肪細胞への分化を誘導する方法
US20070179085A1 (en) 2005-07-20 2007-08-02 Savani Rashmin C Modulation of rhamm-caveolin/lipid raft interactions to affect development, responses to tissue injury, angiogenesis, tumorigenesis, metastasis and growth factor/cytokine responses
US20070292869A1 (en) * 2006-03-02 2007-12-20 Ppd Biomarker Discovery Sciences, Llc Compositions and Methods for Analyzing Renal Cancer
US8066691B2 (en) 2006-04-21 2011-11-29 Khouri Roger K Method and system for preparing soft tissue for grafting, enhancing grafting results, and grafting autologous fat to soft tissue such as the breast
EP2079460B1 (fr) 2006-10-20 2018-11-21 NUTRICOS Technologies Utilisation cosmetique par voie orale de la glucosamine eventuellement associee a au moins un compose polyphenol
US20100062000A1 (en) 2006-11-21 2010-03-11 The Regents Of The University Of California Rhamm, a Co-Receptor and Its Interactions with Other Receptors in Cancer Cell Motility and the Identification of Cancer Prognitor Cell Populations
AU2007353332B2 (en) 2006-11-21 2013-08-01 The Regents Of The University Of California Modulation of Rhamm (CD168) for selective adipose tissue development
EP1967524A1 (en) * 2007-03-06 2008-09-10 Friesland Brands B.V. Methods for producing ACE-inhibitory peptides from whey and peptides obtained thereby
WO2009036246A2 (en) 2007-09-14 2009-03-19 Immunotope, Inc. Immunogens that induce cytotoxic t-lymphocytes and their use in prevention, treatment, and diagnosis of cancer
EP2197908A2 (en) * 2007-09-27 2010-06-23 Dako Denmark A/S Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics
US20100290989A1 (en) 2007-10-12 2010-11-18 London Health Sciences Centre Research Inc. Compositions affecting hyaluronic acid mediated activity
WO2009061130A2 (en) 2007-11-06 2009-05-14 Procell Therapeutics Inc. Cell permeable runx3 recombinant proteins, polynucleotides encoding the same, and anticancer compositions including the same
US8216828B2 (en) 2008-05-30 2012-07-10 Corning Incorporated Assembly of cell culture vessels
CN106188270A (zh) 2010-05-31 2016-12-07 伦敦健康科学研究中心有限公司 Rhamm结合肽
CA2809847A1 (en) 2010-09-01 2012-03-08 The Regents Of The University Of California Cell culture screen for agents that control adipogenesis and myofibroblast differentiation
US20120076810A1 (en) 2010-09-01 2012-03-29 Poland Gregory A Vaccinia virus polypeptides
BR112013005448A2 (pt) * 2010-09-07 2019-09-24 Oncotherapy Science Inc peptídeos de ttll4 e vacinas contendo os mesmos.
EP2922869B1 (en) 2012-11-25 2017-09-27 The Regents of The University of California Peptides that stimulate subcutaneous adipogenesis
US10844102B2 (en) 2014-05-28 2020-11-24 The Regents Of The University Of California Peptides, compositions, and methods for stimulating subcutaneous adipogenesis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190128603A (ko) * 2018-05-08 2019-11-18 경상대학교산학협력단 주름개선 효능을 갖는 펩티드
WO2020111743A1 (ko) * 2018-11-26 2020-06-04 한국해양과학기술원 지방 생성을 자극하는 펩타이드, 조성 및 방법

Also Published As

Publication number Publication date
RU2015123315A (ru) 2017-01-10
US20150284433A1 (en) 2015-10-08
US10766927B2 (en) 2020-09-08
IL239008A0 (en) 2015-07-30
US10494402B2 (en) 2019-12-03
WO2014082042A2 (en) 2014-05-30
EP2922869A2 (en) 2015-09-30
CA2930117A1 (en) 2014-05-30
US20140179616A1 (en) 2014-06-26
CN105008396A (zh) 2015-10-28
EP2922869B1 (en) 2017-09-27
JP2016501866A (ja) 2016-01-21
AU2013347797A1 (en) 2015-07-02
HK1216895A1 (zh) 2016-12-09
WO2014082042A3 (en) 2014-07-24

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PA0105 International application

Patent event date: 20150623

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid