JP2015534564A - 脱髄障害の治療のための併用療法および使用 - Google Patents
脱髄障害の治療のための併用療法および使用 Download PDFInfo
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- JP2015534564A JP2015534564A JP2015535889A JP2015535889A JP2015534564A JP 2015534564 A JP2015534564 A JP 2015534564A JP 2015535889 A JP2015535889 A JP 2015535889A JP 2015535889 A JP2015535889 A JP 2015535889A JP 2015534564 A JP2015534564 A JP 2015534564A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/112—Gait analysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1124—Determining motor skills
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
- A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physiology (AREA)
- Pathology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dentistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Zoology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261711638P | 2012-10-09 | 2012-10-09 | |
US61/711,638 | 2012-10-09 | ||
PCT/US2013/063873 WO2014058875A2 (fr) | 2012-10-09 | 2013-10-08 | Polythérapies et leurs utilisations pour le traitement de troubles de la démyélinisation |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017247590A Division JP2018044014A (ja) | 2012-10-09 | 2017-12-25 | 脱髄障害の治療のための併用療法および使用 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2015534564A true JP2015534564A (ja) | 2015-12-03 |
JP2015534564A5 JP2015534564A5 (fr) | 2016-11-24 |
Family
ID=49484444
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015535889A Withdrawn JP2015534564A (ja) | 2012-10-09 | 2013-10-08 | 脱髄障害の治療のための併用療法および使用 |
JP2017247590A Withdrawn JP2018044014A (ja) | 2012-10-09 | 2017-12-25 | 脱髄障害の治療のための併用療法および使用 |
JP2020004952A Withdrawn JP2020055881A (ja) | 2012-10-09 | 2020-01-16 | 脱髄障害の治療のための併用療法および使用 |
JP2021176294A Pending JP2022023182A (ja) | 2012-10-09 | 2021-10-28 | 脱髄障害の治療のための併用療法および使用 |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017247590A Withdrawn JP2018044014A (ja) | 2012-10-09 | 2017-12-25 | 脱髄障害の治療のための併用療法および使用 |
JP2020004952A Withdrawn JP2020055881A (ja) | 2012-10-09 | 2020-01-16 | 脱髄障害の治療のための併用療法および使用 |
JP2021176294A Pending JP2022023182A (ja) | 2012-10-09 | 2021-10-28 | 脱髄障害の治療のための併用療法および使用 |
Country Status (13)
Country | Link |
---|---|
US (4) | US20150238602A1 (fr) |
EP (2) | EP3750560A3 (fr) |
JP (4) | JP2015534564A (fr) |
KR (2) | KR102257645B1 (fr) |
CN (2) | CN109364250A (fr) |
AU (3) | AU2013329421A1 (fr) |
BR (1) | BR112015007780A2 (fr) |
CA (1) | CA2887682A1 (fr) |
EA (1) | EA201590709A1 (fr) |
HK (1) | HK1213794A1 (fr) |
IL (2) | IL238117B (fr) |
MX (2) | MX2015004436A (fr) |
WO (1) | WO2014058875A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2019524731A (ja) * | 2016-07-13 | 2019-09-05 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | Lingo−1アンタゴニストの投与計画及び脱髄障害の処置のための使用 |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2010005570A2 (fr) | 2008-07-09 | 2010-01-14 | Biogen Idec Ma Inc. | Compositions comprenant des anticorps anti-lingo ou leurs fragments |
EA030716B1 (ru) | 2012-05-14 | 2018-09-28 | Байоджен Ма Инк. | Антагонисты lingo-2 для лечения заболеваний, в которых участвуют двигательные нейроны |
US20170283804A1 (en) * | 2014-09-19 | 2017-10-05 | Ionis Pharmaceuticals, Inc. | Antisense compounds and uses thereof |
MA41139A (fr) | 2014-12-11 | 2017-10-17 | Actelion Pharmaceuticals Ltd | Combinaison pharmaceutique comportant un agoniste sélectif du récepteur sip1 |
US10435467B2 (en) * | 2015-01-08 | 2019-10-08 | Biogen Ma Inc. | LINGO-1 antagonists and uses for treatment of demyelinating disorders |
EP3302465A1 (fr) | 2015-06-05 | 2018-04-11 | Vertex Pharmaceuticals Incorporated | Triazoles pour le traitement de maladies liées à la démyélinisation |
WO2018106641A1 (fr) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Pyrazoles pour le traitement de maladies démyélinisantes |
WO2018106646A1 (fr) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Aminotriazoles pour traiter des maladies démyélinisantes |
WO2018106643A1 (fr) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Azoles hétérocycliques pour le traitement de maladies de démyélinisation |
EP3600553A4 (fr) | 2017-03-26 | 2020-09-02 | Mapi Pharma Ltd. | Systèmes de dépôt de glatiramère pour le traitement de formes progressives de sclérose en plaques |
EP3624838B1 (fr) * | 2017-05-15 | 2023-01-25 | Oncoimmune, Inc. | Procédés d'utilisation de cd24 soluble pour la neuroprotection et la remyélinisation |
US11412968B2 (en) | 2017-09-12 | 2022-08-16 | Get Together, Inc | System and method for a digital therapeutic delivery of generalized clinician tips (GCT) |
CN112153967A (zh) * | 2018-04-13 | 2020-12-29 | 莫迪凯·舍维龙 | 治疗脱髓鞘的组合物和方法 |
CA3144567A1 (fr) | 2019-06-21 | 2020-12-24 | Scott Crowe | Polypeptides |
MX2021015763A (es) | 2019-06-21 | 2022-04-18 | Sorriso Pharmaceuticals Inc | Polipeptidos. |
CN113584041A (zh) * | 2021-04-15 | 2021-11-02 | 浙江警察学院 | 一种转基因斑马鱼(mbp:egfp)脱脊髓疾病模型的构建方法 |
KR20230171226A (ko) * | 2022-06-13 | 2023-12-20 | 고려대학교 산학협력단 | 키나아제 저해제를 유효성분으로 포함하는 탈수초성 질환 예방 또는 치료용 약학적 조성물 |
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- 2013-10-08 US US14/434,292 patent/US20150238602A1/en not_active Abandoned
- 2013-10-08 CN CN201380063471.0A patent/CN104870014A/zh active Pending
- 2013-10-08 EP EP20173044.7A patent/EP3750560A3/fr not_active Withdrawn
- 2013-10-08 KR KR1020157012062A patent/KR102257645B1/ko active IP Right Grant
- 2013-10-08 CA CA2887682A patent/CA2887682A1/fr not_active Abandoned
- 2013-10-08 AU AU2013329421A patent/AU2013329421A1/en not_active Abandoned
- 2013-10-08 EP EP13780458.9A patent/EP2906240A2/fr not_active Withdrawn
- 2013-10-08 KR KR1020217015388A patent/KR20210063443A/ko not_active Application Discontinuation
- 2013-10-08 BR BR112015007780A patent/BR112015007780A2/pt not_active Application Discontinuation
- 2013-10-08 WO PCT/US2013/063873 patent/WO2014058875A2/fr active Application Filing
- 2013-10-08 EA EA201590709A patent/EA201590709A1/ru unknown
- 2013-10-08 MX MX2015004436A patent/MX2015004436A/es unknown
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2015
- 2015-04-02 IL IL23811715A patent/IL238117B/en active IP Right Grant
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2016
- 2016-02-18 HK HK16101834.0A patent/HK1213794A1/zh unknown
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2017
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2018
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2019
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2020
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- 2020-05-15 AU AU2020203196A patent/AU2020203196A1/en not_active Abandoned
- 2020-11-30 US US17/107,554 patent/US20210260185A1/en not_active Abandoned
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JP2019524731A (ja) * | 2016-07-13 | 2019-09-05 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | Lingo−1アンタゴニストの投与計画及び脱髄障害の処置のための使用 |
JP7149257B2 (ja) | 2016-07-13 | 2022-10-06 | バイオジェン・エムエイ・インコーポレイテッド | Lingo-1アンタゴニストの投与計画及び脱髄障害の処置のための使用 |
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AU2013329421A1 (en) | 2015-04-30 |
EP3750560A2 (fr) | 2020-12-16 |
CA2887682A1 (fr) | 2014-04-17 |
US20190038744A1 (en) | 2019-02-07 |
MX2020006431A (es) | 2020-09-17 |
KR20210063443A (ko) | 2021-06-01 |
US20200276303A1 (en) | 2020-09-03 |
AU2018203688A1 (en) | 2018-06-14 |
US20150238602A1 (en) | 2015-08-27 |
JP2018044014A (ja) | 2018-03-22 |
US20210260185A1 (en) | 2021-08-26 |
HK1213794A1 (zh) | 2016-07-15 |
CN109364250A (zh) | 2019-02-22 |
IL269852A (en) | 2019-11-28 |
BR112015007780A2 (pt) | 2017-11-28 |
CN104870014A (zh) | 2015-08-26 |
AU2020203196A1 (en) | 2020-06-04 |
EP2906240A2 (fr) | 2015-08-19 |
IL238117B (en) | 2019-10-31 |
EA201590709A1 (ru) | 2015-09-30 |
KR102257645B1 (ko) | 2021-06-01 |
JP2022023182A (ja) | 2022-02-07 |
IL238117A0 (en) | 2015-05-31 |
IL269852B (en) | 2021-08-31 |
WO2014058875A2 (fr) | 2014-04-17 |
KR20150064752A (ko) | 2015-06-11 |
WO2014058875A3 (fr) | 2014-06-12 |
JP2020055881A (ja) | 2020-04-09 |
EP3750560A3 (fr) | 2021-03-24 |
MX2015004436A (es) | 2015-06-24 |
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