|
US5168062A
(en)
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4866132A
(en)
|
1986-04-17 |
1989-09-12 |
The Research Foundation Of State University Of New York |
Novel radiopaque barium polymer complexes, compositions of matter and articles prepared therefrom
|
|
US5256334A
(en)
|
1988-09-08 |
1993-10-26 |
The Research Foundation Of The State University Of New York |
Homogeneous radiopaque polymer-organobismuth composites
|
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
US5585362A
(en)
|
1989-08-22 |
1996-12-17 |
The Regents Of The University Of Michigan |
Adenovirus vectors for gene therapy
|
|
US5595732A
(en)
|
1991-03-25 |
1997-01-21 |
Hoffmann-La Roche Inc. |
Polyethylene-protein conjugates
|
|
TW197439B
(enExample)
|
1991-04-04 |
1993-01-01 |
Ueno Pharmaceutics Applic Res Co Ltd |
|
|
WO1993003769A1
(en)
|
1991-08-20 |
1993-03-04 |
THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTEMENT OF HEALTH AND HUMAN SERVICES |
Adenovirus mediated transfer of genes to the gastrointestinal tract
|
|
US5283253A
(en)
|
1991-09-23 |
1994-02-01 |
Florida State University |
Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
|
|
US5621083A
(en)
|
1991-11-04 |
1997-04-15 |
Xoma Corporation |
Immunotoxins comprising ribosome-inactivating proteins
|
|
US5252479A
(en)
|
1991-11-08 |
1993-10-12 |
Research Corporation Technologies, Inc. |
Safe vector for gene therapy
|
|
WO1993010076A1
(en)
|
1991-11-22 |
1993-05-27 |
The University Of Mississippi |
Synthesis and optical resolution of the taxol side chain and related compounds
|
|
DK0617706T3
(da)
|
1991-11-25 |
2001-11-12 |
Enzon Inc |
Multivalente antigenbindende proteiner
|
|
US5200534A
(en)
|
1992-03-13 |
1993-04-06 |
University Of Florida |
Process for the preparation of taxol and 10-deacetyltaxol
|
|
FR2688514A1
(fr)
|
1992-03-16 |
1993-09-17 |
Centre Nat Rech Scient |
Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
|
|
WO1993023555A1
(en)
|
1992-05-21 |
1993-11-25 |
The Penn State Research Foundation |
Cultured taxus tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds
|
|
US5686072A
(en)
|
1992-06-17 |
1997-11-11 |
Board Of Regents, The University Of Texas |
Epitope-specific monoclonal antibodies and immunotoxins and uses thereof
|
|
US5274137A
(en)
|
1992-06-23 |
1993-12-28 |
Nicolaou K C |
Intermediates for preparation of taxols
|
|
US5294637A
(en)
|
1992-07-01 |
1994-03-15 |
Bristol-Myers Squibb Company |
Fluoro taxols
|
|
US5202448A
(en)
|
1992-08-14 |
1993-04-13 |
Napro Biotherapeutics, Inc. |
Processes of converting taxanes into baccatin III
|
|
CA2100808A1
(en)
|
1992-10-01 |
1994-04-02 |
Vittorio Farina |
Deoxy paclitaxels
|
|
FR2696463B1
(fr)
|
1992-10-05 |
1994-11-25 |
Rhone Poulenc Rorer Sa |
Procédé d'obtention de la désacétyl-10 baccatine III.
|
|
FR2696464B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
|
|
FR2696458B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Procédé de préparation de dérivés du taxane.
|
|
FR2696462B1
(fr)
|
1992-10-05 |
1994-11-25 |
Rhone Poulenc Rorer Sa |
Procédé d'obtention de la désacétyl-10 baccatine III.
|
|
FR2696461B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Nouveaux dérivés d'analogues du taxol, leur préparation et les compositions qui les contiennent.
|
|
EP1024198A3
(en)
|
1992-12-03 |
2002-05-29 |
Genzyme Corporation |
Pseudo-adenoviral vectors for the gene therapy of haemophiliae
|
|
US5279949A
(en)
|
1992-12-07 |
1994-01-18 |
Board Of Trustees Operating Michigan State University |
Process for the isolation and purification of taxol and taxanes from Taxus spp
|
|
US5346981A
(en)
|
1993-01-13 |
1994-09-13 |
Miles Inc. |
Radiopaque polyurethanes
|
|
US5484892A
(en)
|
1993-05-21 |
1996-01-16 |
Dana-Farber Cancer Institute, Inc. |
Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells
|
|
ATE304604T1
(de)
|
1993-06-24 |
2005-09-15 |
Frank L Graham |
Adenovirus vektoren für gentherapie
|
|
US5824701A
(en)
|
1993-10-20 |
1998-10-20 |
Enzon, Inc. |
Taxane-based prodrugs
|
|
BR9407956A
(pt)
|
1993-10-25 |
1996-11-26 |
Canji Inc |
Composiçao farmacêutica vetor de express o de adenovirus recombinante e kit par reduzir a proliferaçao de células tumorais
|
|
US5643575A
(en)
|
1993-10-27 |
1997-07-01 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
|
US5415869A
(en)
|
1993-11-12 |
1995-05-16 |
The Research Foundation Of State University Of New York |
Taxol formulation
|
|
EP0771208B1
(en)
|
1994-08-12 |
2005-10-19 |
Immunomedics, Inc. |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
|
US5625048A
(en)
|
1994-11-10 |
1997-04-29 |
The Regents Of The University Of California |
Modified green fluorescent proteins
|
|
US5599902A
(en)
|
1994-11-10 |
1997-02-04 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Cancer inhibitory peptides
|
|
CN1510137A
(zh)
|
1994-12-09 |
2004-07-07 |
�۹���ѧ�ĸ�����˾ |
基因的鉴定
|
|
WO1996019487A1
(en)
|
1994-12-22 |
1996-06-27 |
Nissan Chemical Industries, Ltd. |
Organobismuth derivatives and process for producing the same
|
|
US5958713A
(en)
|
1995-01-31 |
1999-09-28 |
Novo Nordisk A/S |
Method of detecting biologically active substances by using green fluorescent protein
|
|
US5670477A
(en)
|
1995-04-20 |
1997-09-23 |
Joseph F. Poduslo |
Method to enhance permeability of the blood/brain blood/nerve bariers to therapeutic agents
|
|
KR100408909B1
(ko)
|
1995-04-21 |
2004-04-29 |
데이꼬꾸 조끼 세이야꾸 가부시키가이샤 |
신규펩티드유도체
|
|
DE69629580D1
(de)
|
1995-10-13 |
2003-09-25 |
Us Gov Health & Human Serv |
Immunotoxin enthaltend ein disulfid-stabilisiertes antikörperfragment
|
|
US5968738A
(en)
|
1995-12-06 |
1999-10-19 |
The Board Of Trustees Of The Leland Stanford Junior University |
Two-reporter FACS analysis of mammalian cells using green fluorescent proteins
|
|
US6020192A
(en)
|
1996-01-18 |
2000-02-01 |
University Of Florida |
Humanized green fluorescent protein genes and methods
|
|
US5874304A
(en)
|
1996-01-18 |
1999-02-23 |
University Of Florida Research Foundation, Inc. |
Humanized green fluorescent protein genes and methods
|
|
US6254868B1
(en)
|
1996-03-20 |
2001-07-03 |
Immunomedics, Inc. |
Glycosylated humanized B-cell specific antibodies
|
|
WO1998008833A1
(en)
|
1996-08-26 |
1998-03-05 |
Bristol-Myers Squibb Company |
Sulfenamide taxane derivatives
|
|
JP4162267B2
(ja)
|
1996-08-27 |
2008-10-08 |
カイロン コーポレイション |
Neisseria meningitidis血清型B複合糖質およびその使用法
|
|
CA2264227A1
(en)
|
1996-09-27 |
1998-04-02 |
Raymond A. Firestone |
Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
|
|
US5976796A
(en)
|
1996-10-04 |
1999-11-02 |
Loma Linda University |
Construction and expression of renilla luciferase and green fluorescent protein fusion genes
|
|
TW371617B
(en)
|
1996-10-09 |
1999-10-11 |
Of Animal And Plant Health Inspection And Quarantine Council Of Agriculture Executive Yuan Bureau |
Method to transplant GFP into autographa californica multiple nuclear polyhedrosis virus for inflicting pest in an attempt to detect and flow up it existence and to improve life span against UV
|
|
US6653104B2
(en)
|
1996-10-17 |
2003-11-25 |
Immunomedics, Inc. |
Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells
|
|
WO1998022451A1
(en)
|
1996-11-19 |
1998-05-28 |
Daiichi Pharmaceutical Co., Ltd. |
Taxol derivatives
|
|
US5977386A
(en)
|
1996-12-24 |
1999-11-02 |
Bristol-Myers Squibb Company |
6-thio-substituted paclitaxels
|
|
JP2002501488A
(ja)
|
1997-03-20 |
2002-01-15 |
アメリカ合衆国 |
Cd22を保有する細胞および腫瘍へ標的化された、組換え抗体および免疫複合体
|
|
US6183744B1
(en)
|
1997-03-24 |
2001-02-06 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
DE69831224T2
(de)
|
1997-05-02 |
2006-03-23 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Immuntoxine, die ein onc protein enthalten, gegen bösartige zellen
|
|
HUP0002521A3
(en)
|
1997-06-20 |
2002-04-29 |
Baker Norton Pharma |
Onium salts of paclitaxel, process for producing them and medicaments comprising the same
|
|
GB9712892D0
(en)
|
1997-06-20 |
1997-08-20 |
Eclagen Ltd |
Identification of mhc binding peptides
|
|
US7288665B1
(en)
|
1997-08-18 |
2007-10-30 |
Florida State University |
Process for selective derivatization of taxanes
|
|
US6080849A
(en)
|
1997-09-10 |
2000-06-27 |
Vion Pharmaceuticals, Inc. |
Genetically modified tumor-targeted bacteria with reduced virulence
|
|
JPH1192468A
(ja)
|
1997-09-17 |
1999-04-06 |
Yakult Honsha Co Ltd |
新規なタキサン誘導体
|
|
JP4153660B2
(ja)
|
1997-10-08 |
2008-09-24 |
株式会社横浜国際バイオ研究所 |
タキソイド誘導体およびその製造方法
|
|
US6046305A
(en)
|
1997-12-12 |
2000-04-04 |
Macromed, Inc. |
Heterofunctionalized star-shaped poly(ethylene gycols) for protein modification
|
|
US5985577A
(en)
|
1998-10-14 |
1999-11-16 |
The Trustees Of Columbia University In The City Of New York |
Protein conjugates containing multimers of green fluorescent protein
|
|
AU782160B2
(en)
|
1999-06-09 |
2005-07-07 |
Immunomedics Inc. |
Immunotherapy of autoimmune disorders using antibodies which target B-cells
|
|
US6323315B1
(en)
|
1999-09-10 |
2001-11-27 |
Basf Aktiengesellschaft |
Dolastatin peptides
|
|
SG138469A1
(en)
|
2001-01-05 |
2008-01-28 |
Pfizer |
Antibodies to insulin-like growth factor i receptor
|
|
GB0105924D0
(en)
|
2001-03-09 |
2001-04-25 |
Microscience Ltd |
Promoter
|
|
US7321026B2
(en)
|
2001-06-27 |
2008-01-22 |
Skytech Technology Limited |
Framework-patched immunoglobulins
|
|
EP1448584B1
(en)
|
2001-09-26 |
2010-05-19 |
The Government of the United States of America as represented by The Secretary of Health and Human Services |
Mutated anti-cd22 antibodies with increased affinity to cd22-expressing leukemia cells
|
|
US20040001828A1
(en)
*
|
2002-02-21 |
2004-01-01 |
Joseph Tuscano |
Treatment methods using anti-CD22 antibodies
|
|
MY139983A
(en)
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
GB0210121D0
(en)
|
2002-05-02 |
2002-06-12 |
Celltech R&D Ltd |
Biological products
|
|
CA2487321A1
(en)
*
|
2002-06-17 |
2003-12-24 |
The Government Of The United States Of America, As Represented By The Se Cretary Of The Department Of Health And Human Services |
Specificity grafting of a murine antibody onto a human framework
|
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
|
US7534427B2
(en)
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
|
NZ551335A
(en)
|
2004-06-18 |
2010-03-26 |
Ambrx Inc |
Antibodies and fragments thereof comprising an non naturally encoded amino acid coupled to a linker
|
|
CN104447992A
(zh)
|
2004-09-23 |
2015-03-25 |
健泰科生物技术公司 |
半胱氨酸改造的抗体和偶联物
|
|
US7255012B2
(en)
|
2004-12-01 |
2007-08-14 |
Rosemount Inc. |
Process fluid flow device with variable orifice
|
|
DK1844074T3
(da)
|
2005-02-03 |
2013-07-15 |
Antitope Ltd |
Humane antistoffer og proteiner
|
|
JP5142707B2
(ja)
*
|
2005-02-08 |
2013-02-13 |
一般財団法人化学及血清療法研究所 |
抗体の改良方法
|
|
CA2644906C
(en)
|
2006-03-06 |
2016-05-10 |
Medimmune, Inc. |
Humanized anti-cd22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
SG172656A1
(en)
*
|
2006-05-30 |
2011-07-28 |
Genentech Inc |
Antibodies and immunoconjugates and uses therefor
|
|
US7985783B2
(en)
*
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
|
CA2671457C
(en)
*
|
2006-12-01 |
2017-09-26 |
Medarex, Inc. |
Human antibodies that bind cd22 and uses thereof
|
|
WO2010096394A2
(en)
*
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
|
PL2516460T3
(pl)
*
|
2009-12-22 |
2015-08-31 |
Hoffmann La Roche |
Agregacja zależna od sekwencji
|
|
UY33679A
(es)
*
|
2010-10-22 |
2012-03-30 |
Esbatech |
Anticuerpos estables y solubles
|
|
KR102165464B1
(ko)
*
|
2012-07-19 |
2020-10-14 |
레드우드 바이오사이언스 인코포레이티드 |
Cd22에 대해 특이적인 항체 및 이들의 사용 방법
|