|
US5168062A
(en)
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4866132A
(en)
|
1986-04-17 |
1989-09-12 |
The Research Foundation Of State University Of New York |
Novel radiopaque barium polymer complexes, compositions of matter and articles prepared therefrom
|
|
US5256334A
(en)
|
1988-09-08 |
1993-10-26 |
The Research Foundation Of The State University Of New York |
Homogeneous radiopaque polymer-organobismuth composites
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
US5585362A
(en)
|
1989-08-22 |
1996-12-17 |
The Regents Of The University Of Michigan |
Adenovirus vectors for gene therapy
|
|
US5595732A
(en)
|
1991-03-25 |
1997-01-21 |
Hoffmann-La Roche Inc. |
Polyethylene-protein conjugates
|
|
TW197439B
(enExample)
|
1991-04-04 |
1993-01-01 |
Ueno Pharmaceutics Applic Res Co Ltd |
|
|
AU663725B2
(en)
|
1991-08-20 |
1995-10-19 |
United States Of America, Represented By The Secretary, Department Of Health And Human Services, The |
Adenovirus mediated transfer of genes to the gastrointestinal tract
|
|
US5283253A
(en)
|
1991-09-23 |
1994-02-01 |
Florida State University |
Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
|
|
US5621083A
(en)
|
1991-11-04 |
1997-04-15 |
Xoma Corporation |
Immunotoxins comprising ribosome-inactivating proteins
|
|
US5252479A
(en)
|
1991-11-08 |
1993-10-12 |
Research Corporation Technologies, Inc. |
Safe vector for gene therapy
|
|
AU3140093A
(en)
|
1991-11-22 |
1993-06-15 |
University Of Mississippi, The |
Synthesis and optical resolution of the taxol side chain and related compounds
|
|
JPH07501451A
(ja)
|
1991-11-25 |
1995-02-16 |
エンゾン・インコーポレイテッド |
多価抗原結合タンパク質
|
|
US5200534A
(en)
|
1992-03-13 |
1993-04-06 |
University Of Florida |
Process for the preparation of taxol and 10-deacetyltaxol
|
|
FR2688514A1
(fr)
|
1992-03-16 |
1993-09-17 |
Centre Nat Rech Scient |
Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
|
|
EP0642586A4
(en)
|
1992-05-21 |
1995-11-29 |
Penn State Res Found |
CULTURAL -i (TAXUS) FABRIC AS A SOURCE OF TAXOL, RELATED TAXANS AND OTHER NEW ANTI-TUMOR / ANTI-VIRAL SUBSTANCES (01/20/94).
|
|
US5686072A
(en)
|
1992-06-17 |
1997-11-11 |
Board Of Regents, The University Of Texas |
Epitope-specific monoclonal antibodies and immunotoxins and uses thereof
|
|
US5274137A
(en)
|
1992-06-23 |
1993-12-28 |
Nicolaou K C |
Intermediates for preparation of taxols
|
|
US5294637A
(en)
|
1992-07-01 |
1994-03-15 |
Bristol-Myers Squibb Company |
Fluoro taxols
|
|
US5202448A
(en)
|
1992-08-14 |
1993-04-13 |
Napro Biotherapeutics, Inc. |
Processes of converting taxanes into baccatin III
|
|
CA2100808A1
(en)
|
1992-10-01 |
1994-04-02 |
Vittorio Farina |
Deoxy paclitaxels
|
|
FR2696458B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Procédé de préparation de dérivés du taxane.
|
|
FR2696461B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Nouveaux dérivés d'analogues du taxol, leur préparation et les compositions qui les contiennent.
|
|
FR2696463B1
(fr)
|
1992-10-05 |
1994-11-25 |
Rhone Poulenc Rorer Sa |
Procédé d'obtention de la désacétyl-10 baccatine III.
|
|
FR2696464B1
(fr)
|
1992-10-05 |
1994-11-10 |
Rhone Poulenc Rorer Sa |
Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
|
|
FR2696462B1
(fr)
|
1992-10-05 |
1994-11-25 |
Rhone Poulenc Rorer Sa |
Procédé d'obtention de la désacétyl-10 baccatine III.
|
|
JPH08503855A
(ja)
|
1992-12-03 |
1996-04-30 |
ジェンザイム・コーポレイション |
嚢胞性線維症に対する遺伝子治療
|
|
US5279949A
(en)
|
1992-12-07 |
1994-01-18 |
Board Of Trustees Operating Michigan State University |
Process for the isolation and purification of taxol and taxanes from Taxus spp
|
|
US5346981A
(en)
|
1993-01-13 |
1994-09-13 |
Miles Inc. |
Radiopaque polyurethanes
|
|
US5484892A
(en)
|
1993-05-21 |
1996-01-16 |
Dana-Farber Cancer Institute, Inc. |
Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells
|
|
ES2249761T3
(es)
|
1993-06-24 |
2006-04-01 |
Advec Inc. |
Vectores de adenovirus para terapia genica.
|
|
US5824701A
(en)
|
1993-10-20 |
1998-10-20 |
Enzon, Inc. |
Taxane-based prodrugs
|
|
SK283703B6
(sk)
|
1993-10-25 |
2003-12-02 |
Canji, Inc. |
Rekombinantný adenovírusový vektor a jeho použitie
|
|
US5643575A
(en)
|
1993-10-27 |
1997-07-01 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
|
US5415869A
(en)
|
1993-11-12 |
1995-05-16 |
The Research Foundation Of State University Of New York |
Taxol formulation
|
|
CA2195557C
(en)
|
1994-08-12 |
2006-10-17 |
Shui-On Leung |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
|
US5599902A
(en)
|
1994-11-10 |
1997-02-04 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Cancer inhibitory peptides
|
|
US5625048A
(en)
|
1994-11-10 |
1997-04-29 |
The Regents Of The University Of California |
Modified green fluorescent proteins
|
|
KR100551104B1
(ko)
|
1994-12-09 |
2006-02-09 |
임페리얼 컬리지 이노베이션스 리미티드 |
유전자의 동정
|
|
AU4188196A
(en)
|
1994-12-22 |
1996-07-10 |
Nissan Chemical Industries Ltd. |
Organobismuth derivatives and process for producing the same
|
|
US5958713A
(en)
|
1995-01-31 |
1999-09-28 |
Novo Nordisk A/S |
Method of detecting biologically active substances by using green fluorescent protein
|
|
US5670477A
(en)
|
1995-04-20 |
1997-09-23 |
Joseph F. Poduslo |
Method to enhance permeability of the blood/brain blood/nerve bariers to therapeutic agents
|
|
AU704973B2
(en)
|
1995-04-21 |
1999-05-13 |
Teikoku Hormone Mfg. Co., Ltd. |
Novel peptide derivatives
|
|
JPH11513669A
(ja)
|
1995-10-13 |
1999-11-24 |
アメリカ合衆国 |
ジスルフィド安定化抗体フラグメントを含む免疫毒素
|
|
US5968738A
(en)
|
1995-12-06 |
1999-10-19 |
The Board Of Trustees Of The Leland Stanford Junior University |
Two-reporter FACS analysis of mammalian cells using green fluorescent proteins
|
|
US6020192A
(en)
|
1996-01-18 |
2000-02-01 |
University Of Florida |
Humanized green fluorescent protein genes and methods
|
|
US5874304A
(en)
|
1996-01-18 |
1999-02-23 |
University Of Florida Research Foundation, Inc. |
Humanized green fluorescent protein genes and methods
|
|
EP0888125B1
(en)
|
1996-03-20 |
2004-05-26 |
Immunomedics, Inc. |
GLYCOSYLATED IgG ANTIBODIES
|
|
AU3740997A
(en)
|
1996-08-26 |
1998-03-19 |
Bristol-Myers Squibb Company |
Sulfenamide taxane derivatives
|
|
JP4162267B2
(ja)
|
1996-08-27 |
2008-10-08 |
カイロン コーポレイション |
Neisseria meningitidis血清型B複合糖質およびその使用法
|
|
CA2264227A1
(en)
|
1996-09-27 |
1998-04-02 |
Raymond A. Firestone |
Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
|
|
US5976796A
(en)
|
1996-10-04 |
1999-11-02 |
Loma Linda University |
Construction and expression of renilla luciferase and green fluorescent protein fusion genes
|
|
TW371617B
(en)
|
1996-10-09 |
1999-10-11 |
Of Animal And Plant Health Inspection And Quarantine Council Of Agriculture Executive Yuan Bureau |
Method to transplant GFP into autographa californica multiple nuclear polyhedrosis virus for inflicting pest in an attempt to detect and flow up it existence and to improve life span against UV
|
|
US6653104B2
(en)
|
1996-10-17 |
2003-11-25 |
Immunomedics, Inc. |
Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells
|
|
WO1998022451A1
(en)
|
1996-11-19 |
1998-05-28 |
Daiichi Pharmaceutical Co., Ltd. |
Taxol derivatives
|
|
US5977386A
(en)
|
1996-12-24 |
1999-11-02 |
Bristol-Myers Squibb Company |
6-thio-substituted paclitaxels
|
|
ATE383430T1
(de)
*
|
1997-03-20 |
2008-01-15 |
Us Gov Health & Human Serv |
Rekombinante antikörper und immunkonjugate gezielt auf cd22-tragende zellen und tumoren
|
|
US6183744B1
(en)
|
1997-03-24 |
2001-02-06 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
EP0975674B1
(en)
|
1997-05-02 |
2005-08-17 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services |
Immunotoxins, comprising an onc protein, directed against malignant cells
|
|
GB9712892D0
(en)
|
1997-06-20 |
1997-08-20 |
Eclagen Ltd |
Identification of mhc binding peptides
|
|
CA2294606A1
(en)
|
1997-06-20 |
1998-12-30 |
Baker Norton Pharmaceuticals, Inc. |
Soluble prodrugs of paclitaxel
|
|
US7288665B1
(en)
|
1997-08-18 |
2007-10-30 |
Florida State University |
Process for selective derivatization of taxanes
|
|
US6080849A
(en)
|
1997-09-10 |
2000-06-27 |
Vion Pharmaceuticals, Inc. |
Genetically modified tumor-targeted bacteria with reduced virulence
|
|
JPH1192468A
(ja)
|
1997-09-17 |
1999-04-06 |
Yakult Honsha Co Ltd |
新規なタキサン誘導体
|
|
AU741433B2
(en)
|
1997-10-08 |
2001-11-29 |
Bio Research Corporation Of Yokohama |
Taxoid derivatives and process for producing the same
|
|
AR014621A1
(es)
|
1997-12-12 |
2001-03-28 |
Macromed Inc |
Un poli (etilenglicol) con forma de estrella, heterofuncional, biocompatible, metodo para su obtencion y metodo para conjugarlo con una proteina
|
|
US5985577A
(en)
|
1998-10-14 |
1999-11-16 |
The Trustees Of Columbia University In The City Of New York |
Protein conjugates containing multimers of green fluorescent protein
|
|
EP1194167B1
(en)
|
1999-06-09 |
2009-08-19 |
Immunomedics, Inc. |
Immunotherapy of autoimmune disorders using antibodies which target b-cells
|
|
US6323315B1
(en)
|
1999-09-10 |
2001-11-27 |
Basf Aktiengesellschaft |
Dolastatin peptides
|
|
EP2796468A2
(en)
|
2001-01-05 |
2014-10-29 |
Pfizer Inc |
Antibodies to insulin-like growth factor I receptor
|
|
GB0105924D0
(en)
|
2001-03-09 |
2001-04-25 |
Microscience Ltd |
Promoter
|
|
US7321026B2
(en)
*
|
2001-06-27 |
2008-01-22 |
Skytech Technology Limited |
Framework-patched immunoglobulins
|
|
ATE468348T1
(de)
|
2001-09-26 |
2010-06-15 |
Government Of The Us Secretary |
Mutierte anti-cd22-antikörper mit erhöhter affinität zu cd22-exprimierenden leukämiezellen
|
|
WO2003072736A2
(en)
*
|
2002-02-21 |
2003-09-04 |
Duke University |
Reagents and treatment methods for autoimmune diseases
|
|
MY139983A
(en)
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
GB0210121D0
(en)
|
2002-05-02 |
2002-06-12 |
Celltech R&D Ltd |
Biological products
|
|
US7456260B2
(en)
|
2002-06-17 |
2008-11-25 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Humanized antibody
|
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
|
US7534427B2
(en)
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
|
KR101699142B1
(ko)
|
2004-06-18 |
2017-01-23 |
암브룩스, 인코포레이티드 |
신규 항원-결합 폴리펩티드 및 이의 용도
|
|
KR101270829B1
(ko)
|
2004-09-23 |
2013-06-07 |
제넨테크, 인크. |
시스테인 유전자조작 항체 및 접합체
|
|
US7255012B2
(en)
|
2004-12-01 |
2007-08-14 |
Rosemount Inc. |
Process fluid flow device with variable orifice
|
|
JP2008528668A
(ja)
|
2005-02-03 |
2008-07-31 |
アンチトープ リミテッド |
ヒト抗体及びタンパク質
|
|
EP1860120B1
(en)
*
|
2005-02-08 |
2018-01-24 |
The Chemo-Sero-Therapeutic Research Institute |
Method for improving antibody
|
|
AU2007223903B2
(en)
|
2006-03-06 |
2013-09-05 |
Medimmune, Llc |
Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
|
CL2007001536A1
(es)
|
2006-05-30 |
2008-01-25 |
Genentech Inc |
Anticuerpos anti-cd22; polinucleotidos que los codifica; vector y celula huesped que los comprende; metodo de fabricacion; metodo de deteccion del anticuerpo en una muestra biologica; inmunoconjugado que comprende al anticuerpo; composicion que lo comprende y su uso para tratar trastornos proliferativos de celulas b.
|
|
US7985783B2
(en)
*
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
|
BRPI0717902A2
(pt)
*
|
2006-12-01 |
2013-10-29 |
Medarex Inc |
"anticorpo monoclonal humano isolado, composição, conjugado anticorpo-molécula parceria, imunoconjugado, molécula de ácido nucléico isolada, vetor de expressão, célula hospedeira, método para prepar um anticorpo anti-cd22, método para inibir o desenvolvimento de uma célula tumoral que expressa cd22 e método para tratar uma doença inflamatória ou autoimuneem um indivíduo"
|
|
WO2010096394A2
(en)
*
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
|
US9150641B2
(en)
*
|
2009-12-22 |
2015-10-06 |
Hoffmann—La Roche Inc. |
Sequence dependent aggregation
|
|
AR083495A1
(es)
*
|
2010-10-22 |
2013-02-27 |
Esbatech Alcon Biomed Res Unit |
Anticuerpos estables y solubles
|
|
WO2014014821A1
(en)
*
|
2012-07-19 |
2014-01-23 |
Redwood Biosciences, Inc. |
Antibody specific for cd22 and methods of use thereof
|