JP2015530971A5 - - Google Patents
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- JP2015530971A5 JP2015530971A5 JP2015520685A JP2015520685A JP2015530971A5 JP 2015530971 A5 JP2015530971 A5 JP 2015530971A5 JP 2015520685 A JP2015520685 A JP 2015520685A JP 2015520685 A JP2015520685 A JP 2015520685A JP 2015530971 A5 JP2015530971 A5 JP 2015530971A5
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- JP
- Japan
- Prior art keywords
- seq
- tau
- amino acid
- antibody
- acid sequence
- Prior art date
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261667515P | 2012-07-03 | 2012-07-03 | |
| US61/667,515 | 2012-07-03 | ||
| US201261694989P | 2012-08-30 | 2012-08-30 | |
| US61/694,989 | 2012-08-30 | ||
| PCT/US2013/049333 WO2014008404A1 (en) | 2012-07-03 | 2013-07-03 | Antibodies to tau |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018098889A Division JP2018184398A (ja) | 2012-07-03 | 2018-05-23 | タウに対する抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015530971A JP2015530971A (ja) | 2015-10-29 |
| JP2015530971A5 true JP2015530971A5 (https=) | 2016-08-18 |
| JP6345655B2 JP6345655B2 (ja) | 2018-06-20 |
Family
ID=49882495
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015520685A Expired - Fee Related JP6345655B2 (ja) | 2012-07-03 | 2013-07-03 | タウに対する抗体 |
| JP2018098889A Pending JP2018184398A (ja) | 2012-07-03 | 2018-05-23 | タウに対する抗体 |
| JP2020070416A Pending JP2020125310A (ja) | 2012-07-03 | 2020-04-09 | タウに対する抗体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018098889A Pending JP2018184398A (ja) | 2012-07-03 | 2018-05-23 | タウに対する抗体 |
| JP2020070416A Pending JP2020125310A (ja) | 2012-07-03 | 2020-04-09 | タウに対する抗体 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9834596B2 (https=) |
| EP (2) | EP3838921A3 (https=) |
| JP (3) | JP6345655B2 (https=) |
| KR (3) | KR20150036346A (https=) |
| CN (2) | CN104781278B (https=) |
| AU (3) | AU2013286680B2 (https=) |
| BR (1) | BR112014033116B1 (https=) |
| CA (1) | CA2877397A1 (https=) |
| HK (1) | HK1209768A1 (https=) |
| IL (3) | IL236409B (https=) |
| IN (1) | IN2015KN00007A (https=) |
| MX (2) | MX359555B (https=) |
| MY (1) | MY171473A (https=) |
| NZ (2) | NZ703423A (https=) |
| RU (2) | RU2668159C2 (https=) |
| SG (3) | SG10201913370PA (https=) |
| WO (1) | WO2014008404A1 (https=) |
Families Citing this family (54)
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|---|---|---|---|---|
| HK1209768A1 (en) | 2012-07-03 | 2016-04-08 | Washington University | Antibodies to tau |
| PE20150646A1 (es) | 2012-08-16 | 2015-05-21 | Ipierian Inc | Metodos de tratamiento de una tauopatia |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| CA2902026C (en) * | 2013-03-13 | 2023-08-29 | Prothena Biosciences Limited | Tau immunotherapy |
| WO2015122922A1 (en) | 2014-02-14 | 2015-08-20 | Ipierian, Inc. | Tau peptides, anti-tau antibodies, and methods of use thereof |
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| WO2015197820A1 (en) * | 2014-06-26 | 2015-12-30 | Crucell Holland B.V. | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
| ZA201608812B (en) | 2014-06-26 | 2019-08-28 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
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| PL3484916T3 (pl) | 2016-07-12 | 2021-07-19 | H. Lundbeck A/S | Przeciwciała swoiste wobec hiperfosforylowanego białka tau i sposoby ich zastosowania |
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| CN117820467A (zh) | 2016-12-07 | 2024-04-05 | 基因泰克公司 | 抗tau抗体和使用方法 |
| MA48595A (fr) | 2016-12-07 | 2020-03-18 | Ac Immune Sa | Anticorps anti-tau et leurs méthodes d'utilisation |
| CN106749658B (zh) * | 2016-12-15 | 2019-11-12 | 北京师范大学 | 抑制Tau蛋白聚集的抗体型分子伴侣 |
| CN110072888B (zh) | 2016-12-16 | 2023-07-18 | H.隆德贝克有限公司 | 药剂、用途和方法 |
| US10364286B2 (en) * | 2016-12-22 | 2019-07-30 | H. Lundbeck A/S | Monoclonal anti-alpha-synuclein antibodies for preventing tau aggregation |
| BR112019017021A2 (pt) | 2017-02-17 | 2020-04-14 | Denali Therapeutics Inc | anticorpos anti-tau e métodos de uso dos mesmos |
| US11078272B2 (en) * | 2017-03-09 | 2021-08-03 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of pediatric brain tumors with targeting of CD47 pathway |
| CN110881274B (zh) | 2017-05-02 | 2024-11-15 | 普罗塞纳生物科学有限公司 | 识别tau的抗体 |
| EP3697814A1 (en) | 2017-10-16 | 2020-08-26 | Eisai R&D Management Co., Ltd. | Anti-tau antibodies and uses thereof |
| CN112004827A (zh) | 2018-03-23 | 2020-11-27 | 艾伯维德国有限责任两合公司 | 稳定的水性抗tau抗体调配物 |
| EP3784687A1 (en) * | 2018-04-27 | 2021-03-03 | Ecole Polytechnique Federale De Lausanne (Epfl) | A method for preparing phfs-like tau aggregates |
| CA3107788A1 (en) | 2018-07-31 | 2020-02-06 | Eli Lilly And Company | Combination of anti-tau antibody and oga inhibitor for treatment of diseases characterized by aberrant tau aggregation |
| CN109613242A (zh) * | 2018-11-01 | 2019-04-12 | 深圳天辰医疗科技有限公司 | 一种肌酸激酶同工酶检测试剂盒及其制备方法 |
| EP3935083A4 (en) | 2019-03-03 | 2022-11-30 | Prothena Biosciences Limited | Antibodies recognizing tau |
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| CA3159964A1 (en) * | 2019-12-04 | 2021-06-10 | Ac Immune Sa | Novel molecules for therapy and diagnosis |
| WO2022099314A1 (en) * | 2020-11-09 | 2022-05-12 | Meso Scale Technologies, Llc. | Methods and kits for detecting tau |
| US20240101654A1 (en) | 2020-12-29 | 2024-03-28 | Neurimmune Ag | Human anti-tau antibodies |
| IL307170A (en) | 2021-03-26 | 2023-11-01 | Janssen Biotech Inc | Anti-tau antibodies and their uses |
| MX2023011340A (es) | 2021-03-26 | 2023-12-14 | Janssen Biotech Inc | Anticuerpos humanizados contra el filamento helicoidal emparejado tau y usos de estos. |
| CL2021001380A1 (es) | 2021-05-26 | 2022-01-14 | Corporacion Centro Int De Biomedicina Icc | Generación de un nuevo anticuerpo monoclonal sitio específico para la proteína tau y su uso como herramienta en biomarcadores específicos para la detección temprana de enfermedades neurodegenerativas y patologías involucradas con la proteína tau como alzheimer y otras demencias. |
| PE20251318A1 (es) * | 2022-08-23 | 2025-05-16 | Washington University St Louis | Anticuerpos mtbr anti-tau y metodos para detectar fragmentos escindidos de tau y sus usos |
| CN121773336A (zh) * | 2023-07-20 | 2026-03-31 | 拉亚·蒙托柳加亚 | P-tau免疫测定 |
| WO2025216325A1 (ja) * | 2024-04-11 | 2025-10-16 | 国立大学法人東京大学 | 生体から脳間質液中のタウシードを回収する方法 |
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| EP2968548B1 (en) | 2013-03-15 | 2020-09-09 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the generation and use of conformation-specific antibodies |
| CN105143258B (zh) | 2013-03-15 | 2020-06-23 | Ac免疫有限公司 | 抗Tau抗体和使用方法 |
| TWI664190B (zh) | 2014-06-27 | 2019-07-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
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2013
- 2013-07-03 HK HK15110657.6A patent/HK1209768A1/xx unknown
- 2013-07-03 MY MYPI2014704038A patent/MY171473A/en unknown
- 2013-07-03 SG SG10201913370PA patent/SG10201913370PA/en unknown
- 2013-07-03 NZ NZ703423A patent/NZ703423A/en not_active IP Right Cessation
- 2013-07-03 RU RU2015103228A patent/RU2668159C2/ru active
- 2013-07-03 KR KR20157002867A patent/KR20150036346A/ko not_active Abandoned
- 2013-07-03 EP EP20199802.8A patent/EP3838921A3/en not_active Withdrawn
- 2013-07-03 MX MX2014016024A patent/MX359555B/es active IP Right Grant
- 2013-07-03 US US14/412,309 patent/US9834596B2/en active Active
- 2013-07-03 IN IN7KON2015 patent/IN2015KN00007A/en unknown
- 2013-07-03 CN CN201380045706.3A patent/CN104781278B/zh active Active
- 2013-07-03 JP JP2015520685A patent/JP6345655B2/ja not_active Expired - Fee Related
- 2013-07-03 AU AU2013286680A patent/AU2013286680B2/en active Active
- 2013-07-03 BR BR112014033116-2A patent/BR112014033116B1/pt active IP Right Grant
- 2013-07-03 SG SG11201408626YA patent/SG11201408626YA/en unknown
- 2013-07-03 EP EP13813988.6A patent/EP2870176A4/en not_active Withdrawn
- 2013-07-03 WO PCT/US2013/049333 patent/WO2014008404A1/en not_active Ceased
- 2013-07-03 NZ NZ739622A patent/NZ739622A/en not_active IP Right Cessation
- 2013-07-03 KR KR1020207002242A patent/KR20200013072A/ko not_active Ceased
- 2013-07-03 SG SG10201708959WA patent/SG10201708959WA/en unknown
- 2013-07-03 CA CA2877397A patent/CA2877397A1/en not_active Abandoned
- 2013-07-03 KR KR1020207033554A patent/KR102494798B1/ko active Active
- 2013-07-03 RU RU2018132044A patent/RU2018132044A/ru unknown
- 2013-07-03 CN CN201810507442.3A patent/CN108623682A/zh active Pending
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2014
- 2014-12-19 MX MX2022000026A patent/MX2022000026A/es unknown
- 2014-12-23 IL IL236409A patent/IL236409B/en active IP Right Grant
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2017
- 2017-06-02 US US15/612,695 patent/US20180037641A1/en not_active Abandoned
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2018
- 2018-05-23 JP JP2018098889A patent/JP2018184398A/ja active Pending
- 2018-09-17 AU AU2018229564A patent/AU2018229564A1/en not_active Abandoned
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2020
- 2020-04-09 JP JP2020070416A patent/JP2020125310A/ja active Pending
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2021
- 2021-12-21 IL IL289241A patent/IL289241A/en unknown
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