JP2015517402A5 - - Google Patents
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- JP2015517402A5 JP2015517402A5 JP2015512799A JP2015512799A JP2015517402A5 JP 2015517402 A5 JP2015517402 A5 JP 2015517402A5 JP 2015512799 A JP2015512799 A JP 2015512799A JP 2015512799 A JP2015512799 A JP 2015512799A JP 2015517402 A5 JP2015517402 A5 JP 2015517402A5
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- Prior art keywords
- butyl
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- groups
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000000034 method Methods 0.000 claims 24
- 125000000217 alkyl group Chemical group 0.000 claims 16
- 239000000463 material Substances 0.000 claims 12
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 11
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 10
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 10
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 10
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 10
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 9
- 230000005526 G1 to G0 transition Effects 0.000 claims 9
- 239000011148 porous material Substances 0.000 claims 9
- 235000013877 carbamide Nutrition 0.000 claims 7
- 239000011162 core material Substances 0.000 claims 7
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 6
- 150000001408 amides Chemical class 0.000 claims 6
- 125000003118 aryl group Chemical group 0.000 claims 6
- 125000000524 functional group Chemical group 0.000 claims 6
- 125000000623 heterocyclic group Chemical group 0.000 claims 6
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims 6
- 230000014759 maintenance of location Effects 0.000 claims 6
- 150000003568 thioethers Chemical class 0.000 claims 6
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 claims 6
- 150000003852 triazoles Chemical class 0.000 claims 6
- 150000002148 esters Chemical class 0.000 claims 5
- 125000001153 fluoro group Chemical group F* 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 4
- 150000001412 amines Chemical class 0.000 claims 4
- 239000004202 carbamide Substances 0.000 claims 4
- 238000004587 chromatography analysis Methods 0.000 claims 4
- 150000002431 hydrogen Chemical class 0.000 claims 4
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims 3
- 238000010485 C−C bond formation reaction Methods 0.000 claims 3
- GNVMUORYQLCPJZ-UHFFFAOYSA-M Thiocarbamate Chemical compound NC([S-])=O GNVMUORYQLCPJZ-UHFFFAOYSA-M 0.000 claims 3
- 239000012491 analyte Substances 0.000 claims 3
- 150000004657 carbamic acid derivatives Chemical class 0.000 claims 3
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims 3
- 150000002170 ethers Chemical class 0.000 claims 3
- 125000005842 heteroatom Chemical group 0.000 claims 3
- 150000003949 imides Chemical class 0.000 claims 3
- 125000003010 ionic group Chemical group 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 claims 3
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 claims 3
- 150000003462 sulfoxides Chemical class 0.000 claims 3
- 239000002344 surface layer Substances 0.000 claims 3
- 150000003672 ureas Chemical class 0.000 claims 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 2
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- -1 cyano, hydroxyl Chemical group 0.000 claims 2
- FDYPWIDITZJTAI-UHFFFAOYSA-N n-ethyl-n-trimethoxysilylethanamine Chemical compound CCN(CC)[Si](OC)(OC)OC FDYPWIDITZJTAI-UHFFFAOYSA-N 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 229910000077 silane Inorganic materials 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 239000011593 sulfur Substances 0.000 claims 2
- XVZMLSWFBPLMEA-UHFFFAOYSA-N trimethoxy(2-pyridin-2-ylethyl)silane Chemical compound CO[Si](OC)(OC)CCC1=CC=CC=N1 XVZMLSWFBPLMEA-UHFFFAOYSA-N 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- 229920001400 block copolymer Polymers 0.000 claims 1
- 229910002092 carbon dioxide Inorganic materials 0.000 claims 1
- 239000001569 carbon dioxide Substances 0.000 claims 1
- 238000013375 chromatographic separation Methods 0.000 claims 1
- 150000002009 diols Chemical class 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 229910010272 inorganic material Inorganic materials 0.000 claims 1
- 239000011147 inorganic material Substances 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 230000001788 irregular Effects 0.000 claims 1
- 239000010410 layer Substances 0.000 claims 1
- 150000004706 metal oxides Chemical group 0.000 claims 1
- 230000000116 mitigating effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- XIQGSQJCEPBGBB-UHFFFAOYSA-N nitrooxy-N-oxoboronamidic acid Chemical compound [N+](=O)([O-])OB(O)N=O XIQGSQJCEPBGBB-UHFFFAOYSA-N 0.000 claims 1
- 125000003107 substituted aryl group Chemical group 0.000 claims 1
- 238000004808 supercritical fluid chromatography Methods 0.000 claims 1
- 239000004753 textile Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261647303P | 2012-05-15 | 2012-05-15 | |
| US61/647,303 | 2012-05-15 | ||
| PCT/US2013/041207 WO2013173494A1 (en) | 2012-05-15 | 2013-05-15 | Chromatographic materials |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015517402A JP2015517402A (ja) | 2015-06-22 |
| JP2015517402A5 true JP2015517402A5 (https=) | 2016-06-30 |
Family
ID=49584263
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512799A Pending JP2015517402A (ja) | 2012-05-15 | 2013-05-15 | クロマトグラフィー材料 |
| JP2015512802A Expired - Fee Related JP6401151B2 (ja) | 2012-05-15 | 2013-05-15 | クロマトグラフィー材料 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512802A Expired - Fee Related JP6401151B2 (ja) | 2012-05-15 | 2013-05-15 | クロマトグラフィー材料 |
Country Status (8)
| Country | Link |
|---|---|
| US (9) | US9925521B2 (https=) |
| EP (1) | EP3113857B1 (https=) |
| JP (2) | JP2015517402A (https=) |
| CN (3) | CN107754776B (https=) |
| DE (2) | DE112013002532T5 (https=) |
| GB (3) | GB2553727B (https=) |
| HK (1) | HK1211258A1 (https=) |
| WO (3) | WO2013173501A2 (https=) |
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| US11092574B2 (en) | 2013-12-24 | 2021-08-17 | Waters Technologies Corporation | Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides |
| JP6821435B2 (ja) * | 2014-03-01 | 2021-01-27 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 不飽和分子を分離するためのクロマトグラフィー材料 |
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| EP3266870A4 (en) * | 2015-03-05 | 2018-10-17 | The University of Tokyo | Conjugate and use thereof |
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| EP2262576B1 (en) | 2008-04-08 | 2025-03-12 | Waters Technologies Corporation | Composite materials containing nanoparticles and their use in chromatography |
| DE102008032687B4 (de) | 2008-07-02 | 2021-05-06 | Hansgrohe Se | Befestigungsanordnung für wasserdurchflossene Sanitärbauteile |
| US20100061367A1 (en) | 2008-09-11 | 2010-03-11 | Pradeep Sindhu | Methods and apparatus related to lossless operation within a data center |
| SG171795A1 (en) | 2008-11-26 | 2011-07-28 | Univ College Cork Nat Univ Ie | A process for preparing silica microparticles |
| JP6151021B2 (ja) * | 2009-06-01 | 2017-06-21 | ウオーターズ・テクノロジーズ・コーポレイシヨン | クロマトグラフ分離用ハイブリッド材料 |
| US10150098B2 (en) | 2009-08-04 | 2018-12-11 | Waters Technologies Corporation | High purity chromatographic materials comprising an ionizable modifier |
| GB2473814B (en) * | 2009-09-16 | 2014-06-11 | Spheritech Ltd | Hollow particulate support |
| US8748582B2 (en) * | 2009-10-15 | 2014-06-10 | Monash University | Affinity ligands and methods for protein purification |
| CN109078626A (zh) * | 2009-12-15 | 2018-12-25 | 沃特世科技公司 | 实施体积排阻色谱的设备和方法 |
| JP5856162B2 (ja) | 2010-07-26 | 2016-02-09 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 粒度分布の狭い実質的に非多孔質のハイブリッドコアを含む表面多孔質材料 |
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2013
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