JP2019534883A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019534883A5 JP2019534883A5 JP2019519219A JP2019519219A JP2019534883A5 JP 2019534883 A5 JP2019534883 A5 JP 2019534883A5 JP 2019519219 A JP2019519219 A JP 2019519219A JP 2019519219 A JP2019519219 A JP 2019519219A JP 2019534883 A5 JP2019534883 A5 JP 2019534883A5
- Authority
- JP
- Japan
- Prior art keywords
- acceptable salt
- pharmaceutically acceptable
- stereoisomer
- item
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662404592P | 2016-10-05 | 2016-10-05 | |
| US62/404,592 | 2016-10-05 | ||
| PCT/US2017/055109 WO2018067685A1 (en) | 2016-10-05 | 2017-10-04 | Small molecule ampk activators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019534883A JP2019534883A (ja) | 2019-12-05 |
| JP2019534883A5 true JP2019534883A5 (https=) | 2020-11-12 |
| JP7034152B2 JP7034152B2 (ja) | 2022-03-11 |
Family
ID=61832129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019519219A Active JP7034152B2 (ja) | 2016-10-05 | 2017-10-04 | 小分子ａｍｐｋ活性化剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11040935B2 (https=) |
| EP (1) | EP3522877B1 (https=) |
| JP (1) | JP7034152B2 (https=) |
| KR (1) | KR20190096949A (https=) |
| CN (1) | CN110035745B (https=) |
| AU (1) | AU2017340403B2 (https=) |
| RU (1) | RU2766146C2 (https=) |
| WO (1) | WO2018067685A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3522877B1 (en) | 2016-10-05 | 2023-12-06 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Small molecule ampk activators |
| AU2020345766A1 (en) | 2019-09-10 | 2022-03-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods and materials for increasing level of phosphorylated AMPK protein |
| CN111925345B (zh) * | 2020-08-21 | 2023-09-29 | 上海科利生物医药有限公司 | 一种手性2-氨甲基四氢呋喃的制备方法 |
| US20250129093A1 (en) * | 2022-02-15 | 2025-04-24 | The Children's Medical Center Corporation | Compositions and methods relating to atp/p2x7r signaling inhibition |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2547524A1 (de) * | 1975-10-23 | 1977-04-28 | Bayer Ag | Disubstituierte phenolaether des 3-amino-2-hydroxypropans, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| JPS5726653A (en) | 1980-05-09 | 1982-02-12 | Ciba Geigy Ag | Substituted phenyl ether |
| US4410472A (en) | 1982-01-15 | 1983-10-18 | Aluminum Company Of America | Method for making spherical binderless pellets |
| US4552960A (en) | 1983-06-20 | 1985-11-12 | Eli Lilly And Company | Fungicidal amines |
| DE4017019A1 (de) | 1990-05-26 | 1991-11-28 | Hoechst Ag | Verwendung von substituierten ss-hydroxyethylaminen als potente hemmstoffe der exoenzyme von pilzen |
| TW205034B (https=) * | 1990-09-13 | 1993-05-01 | Pola Kasei Kogyo Kk | |
| FI924053A7 (fi) | 1991-09-14 | 1993-03-15 | Hoechst Ag | Substituoidut aminopropaanit, menetelmä niiden valmistamiseksi ja niiden käyttö |
| US5541204A (en) | 1994-12-02 | 1996-07-30 | Bristol-Myers Squibb Company | Aryloxypropanolamine β 3 adrenergic agonists |
| MXPA01011956A (es) * | 1999-05-27 | 2002-06-21 | Dimensional Pharm Inc | Oxazaheterociclos como inhibidores de proteasas. |
| AUPQ841300A0 (en) * | 2000-06-27 | 2000-07-20 | Fujisawa Pharmaceutical Co., Ltd. | New aminoalcohol derivatives |
| US6395762B1 (en) * | 2000-07-17 | 2002-05-28 | American Home Products Corporation | Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists |
| US6476016B2 (en) * | 2000-07-17 | 2002-11-05 | 3-Dimensional Pharmaceuticals, Inc. | Cyclic oxyguanidine pyrazinones as protease inhibitors |
| WO2003024953A1 (en) * | 2000-08-10 | 2003-03-27 | Nisshin Pharma Inc. | Propanolamine derivative having 1,4-benzodioxane ring |
| AR035605A1 (es) | 2000-12-11 | 2004-06-16 | Bayer Corp | Derivados de aminometil cromano di-sustituidos, un metodo para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la manufactura de medicamentos utiles como agonistas beta-3-adreno-receptores |
| DE10219542A1 (de) * | 2001-06-05 | 2002-12-12 | Merck Patent Gmbh | CF2O-verbrückte, axial substituierte Cyclohexan-Derivate |
| US20030158195A1 (en) | 2001-12-21 | 2003-08-21 | Cywin Charles L. | 1,6 naphthyridines useful as inhibitors of SYK kinase |
| EP1575495A4 (en) | 2002-03-27 | 2009-12-02 | Smithkline Beecham Corp | COMPOUNDS AND METHODS |
| EP1754483A1 (en) * | 2005-08-18 | 2007-02-21 | Merck Sante | Use of thienopyridone derivatives as AMPK activators and pharmaceutical compositions containing them |
| US20090275611A1 (en) * | 2006-04-07 | 2009-11-05 | Boehringer Ingelheim International Gmbh | Compounds Which Modulate The CB2 Receptor |
| ITMI20061581A1 (it) * | 2006-08-04 | 2008-02-05 | Univ Bari | Ligandi del recettore beta-3 adrenergico e loro uso in terapia |
| WO2008142454A1 (en) * | 2007-05-22 | 2008-11-27 | Prosidion Limited | Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders |
| US20100029689A1 (en) * | 2008-07-02 | 2010-02-04 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors |
| US20100279997A1 (en) | 2009-05-04 | 2010-11-04 | Lindsay Burns Barbier | Analgesic that binds filamin a |
| EP2882428B1 (en) | 2012-07-13 | 2019-01-16 | Pain Therapeutics, Inc. | A method of inhibiting tau phosphorylation |
| WO2014012054A1 (en) | 2012-07-13 | 2014-01-16 | Pain Therapeutics, Inc. | Alzheimer's disease assay in a living patent |
| WO2014144130A2 (en) | 2013-03-15 | 2014-09-18 | Als Mountain Llc | Pharmaceutical composition comprising an ampk activator and a serotonergic agent and methods of use thereof |
| US9433604B2 (en) | 2013-10-08 | 2016-09-06 | Pain Therapeutics Inc. | Method for inhibiting growth of cancer cells |
| EP3522877B1 (en) | 2016-10-05 | 2023-12-06 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Small molecule ampk activators |
-
2017
- 2017-10-04 EP EP17859107.9A patent/EP3522877B1/en active Active
- 2017-10-04 AU AU2017340403A patent/AU2017340403B2/en not_active Ceased
- 2017-10-04 WO PCT/US2017/055109 patent/WO2018067685A1/en not_active Ceased
- 2017-10-04 RU RU2019113149A patent/RU2766146C2/ru active
- 2017-10-04 JP JP2019519219A patent/JP7034152B2/ja active Active
- 2017-10-04 KR KR1020197012800A patent/KR20190096949A/ko not_active Ceased
- 2017-10-04 CN CN201780075212.8A patent/CN110035745B/zh active Active
- 2017-10-04 US US16/339,534 patent/US11040935B2/en active Active
-
2021
- 2021-05-06 US US17/313,577 patent/US11673853B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019534883A5 (https=) | ||
| JP2016518430A5 (https=) | ||
| JP2013508288A5 (https=) | ||
| JP2015520143A5 (https=) | ||
| JP2011037841A5 (https=) | ||
| RU2011102587A (ru) | Дизамещенные фенильные соединения | |
| JP2010535722A5 (https=) | ||
| JP2015531371A5 (https=) | ||
| DE05705627T1 (de) | Trägerampholyte mit hohem ph-wert-bereich | |
| JP2015523383A5 (https=) | ||
| JP2011137045A5 (https=) | ||
| JP2019513770A5 (https=) | ||
| JP2016531126A5 (https=) | ||
| RU2018110372A (ru) | Полоски с хирургическими скобами, допускающие наличие скоб с переменными свойствами и обеспечивающие простую загрузку кассеты | |
| RU2012123154A (ru) | Способы лечения синдрома фибромиалгии | |
| ME02754B (me) | Ligandi opioidnih receptora i postupci njihove upotrebe i pripreme | |
| JP2015509098A5 (https=) | ||
| RU2016118399A (ru) | Производные 4-аминометилбензойной кислоты | |
| AR082519A1 (es) | Fenilamidinas que tienen alta actividad fungicida, y su utilizacion | |
| RU2015131103A (ru) | Синергические фунгицидные смеси для борьбы с грибковыми болезнями злаков | |
| JP2015518821A5 (https=) | ||
| RU2015122126A (ru) | Производное пиррол сульфонамида, метод его получения и применение в медицине | |
| JP2017521436A5 (https=) | ||
| JP2022518741A5 (https=) | ||
| RU2017115809A (ru) | Комбинированная терапия ингибиторами с-с хемокинового рецептора 9 (ccr9) и антителами, блокирующими альфа4бета7-интегрин |