JP2015515493A5 - - Google Patents
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- Publication number
- JP2015515493A5 JP2015515493A5 JP2015509056A JP2015509056A JP2015515493A5 JP 2015515493 A5 JP2015515493 A5 JP 2015515493A5 JP 2015509056 A JP2015509056 A JP 2015509056A JP 2015509056 A JP2015509056 A JP 2015509056A JP 2015515493 A5 JP2015515493 A5 JP 2015515493A5
- Authority
- JP
- Japan
- Prior art keywords
- extract
- tomato
- composition
- composition according
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000284 extract Substances 0.000 claims description 77
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims description 60
- 240000003768 Solanum lycopersicum Species 0.000 claims description 60
- 238000000034 method Methods 0.000 claims description 53
- 239000000203 mixture Substances 0.000 claims description 53
- 230000000694 effects Effects 0.000 claims description 18
- 206010020772 Hypertension Diseases 0.000 claims description 16
- 235000013399 edible fruits Nutrition 0.000 claims description 14
- 235000000346 sugar Nutrition 0.000 claims description 10
- 239000003814 drug Substances 0.000 claims description 9
- 239000000706 filtrate Substances 0.000 claims description 9
- 150000001875 compounds Chemical class 0.000 claims description 8
- 239000012141 concentrate Substances 0.000 claims description 8
- 235000008504 concentrate Nutrition 0.000 claims description 8
- 208000029078 coronary artery disease Diseases 0.000 claims description 8
- 238000000108 ultra-filtration Methods 0.000 claims description 7
- 239000002775 capsule Substances 0.000 claims description 6
- 230000001575 pathological effect Effects 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 206010002329 Aneurysm Diseases 0.000 claims description 4
- 201000001320 Atherosclerosis Diseases 0.000 claims description 4
- 206010007559 Cardiac failure congestive Diseases 0.000 claims description 4
- 201000005569 Gout Diseases 0.000 claims description 4
- 206010019280 Heart failures Diseases 0.000 claims description 4
- 208000007177 Left Ventricular Hypertrophy Diseases 0.000 claims description 4
- 206010038926 Retinopathy hypertensive Diseases 0.000 claims description 4
- 208000006011 Stroke Diseases 0.000 claims description 4
- 208000001871 Tachycardia Diseases 0.000 claims description 4
- 206010012601 diabetes mellitus Diseases 0.000 claims description 4
- 201000001948 hypertensive retinopathy Diseases 0.000 claims description 4
- 208000010125 myocardial infarction Diseases 0.000 claims description 4
- 208000031225 myocardial ischemia Diseases 0.000 claims description 4
- 230000008085 renal dysfunction Effects 0.000 claims description 4
- 239000008299 semisolid dosage form Substances 0.000 claims description 4
- 239000007909 solid dosage form Substances 0.000 claims description 4
- 230000006794 tachycardia Effects 0.000 claims description 4
- 235000015113 tomato pastes and purées Nutrition 0.000 claims description 4
- 238000005119 centrifugation Methods 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 150000008163 sugars Chemical class 0.000 claims description 3
- 239000006188 syrup Substances 0.000 claims description 3
- 235000020357 syrup Nutrition 0.000 claims description 3
- 230000006931 brain damage Effects 0.000 claims description 2
- 231100000874 brain damage Toxicity 0.000 claims description 2
- 208000029028 brain injury Diseases 0.000 claims description 2
- 238000007865 diluting Methods 0.000 claims description 2
- 238000004128 high performance liquid chromatography Methods 0.000 claims description 2
- 239000013618 particulate matter Substances 0.000 claims description 2
- 102000004270 Peptidyl-Dipeptidase A Human genes 0.000 description 21
- 108090000882 Peptidyl-Dipeptidase A Proteins 0.000 description 21
- UUUHXMGGBIUAPW-UHFFFAOYSA-N 1-[1-[2-[[5-amino-2-[[1-[5-(diaminomethylideneamino)-2-[[1-[3-(1h-indol-3-yl)-2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbon Chemical compound C1CCC(C(=O)N2C(CCC2)C(O)=O)N1C(=O)C(C(C)CC)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C1CCC(=O)N1 UUUHXMGGBIUAPW-UHFFFAOYSA-N 0.000 description 17
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 5
- 210000004623 platelet-rich plasma Anatomy 0.000 description 5
- 235000015067 sauces Nutrition 0.000 description 5
- 235000014347 soups Nutrition 0.000 description 5
- 239000004480 active ingredient Substances 0.000 description 3
- 239000006286 aqueous extract Substances 0.000 description 3
- 230000036772 blood pressure Effects 0.000 description 3
- 230000036996 cardiovascular health Effects 0.000 description 3
- 239000008194 pharmaceutical composition Substances 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 3
- 239000005541 ACE inhibitor Substances 0.000 description 2
- 208000018152 Cerebral disease Diseases 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 241000208292 Solanaceae Species 0.000 description 2
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 description 2
- 239000002220 antihypertensive agent Substances 0.000 description 2
- 229940127088 antihypertensive drug Drugs 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 239000007937 lozenge Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 206010053567 Coagulopathies Diseases 0.000 description 1
- 235000014678 Fruitflow® Nutrition 0.000 description 1
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 1
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 230000003276 anti-hypertensive effect Effects 0.000 description 1
- 230000000702 anti-platelet effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 description 1
- 229960004999 lycopene Drugs 0.000 description 1
- 235000012661 lycopene Nutrition 0.000 description 1
- 239000001751 lycopene Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000002777 nucleoside Substances 0.000 description 1
- 125000003835 nucleoside group Chemical group 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261636813P | 2012-04-23 | 2012-04-23 | |
| US61/636,813 | 2012-04-23 | ||
| PCT/US2013/037524 WO2013163057A1 (en) | 2012-04-23 | 2013-04-22 | Use of tomato extract as antihypertensive agent and process for making water soluble sugar free tomato extract |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018211985A Division JP2019038844A (ja) | 2012-04-23 | 2018-11-12 | 抗高血圧症薬としてのトマト抽出物の使用及び水溶性の糖を含まないトマト抽出物の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015515493A JP2015515493A (ja) | 2015-05-28 |
| JP2015515493A5 true JP2015515493A5 (enExample) | 2016-06-16 |
Family
ID=48225147
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015509056A Pending JP2015515493A (ja) | 2012-04-23 | 2013-04-22 | 抗高血圧症薬としてのトマト抽出物の使用及び水溶性の糖を含まないトマト抽出物の製造方法 |
| JP2018211985A Pending JP2019038844A (ja) | 2012-04-23 | 2018-11-12 | 抗高血圧症薬としてのトマト抽出物の使用及び水溶性の糖を含まないトマト抽出物の製造方法 |
| JP2020156083A Pending JP2021008474A (ja) | 2012-04-23 | 2020-09-17 | 抗高血圧症薬としてのトマト抽出物の使用及び水溶性の糖を含まないトマト抽出物の製造方法 |
| JP2022165980A Pending JP2023009053A (ja) | 2012-04-23 | 2022-10-17 | 抗高血圧症薬としてのトマト抽出物の使用及び水溶性の糖を含まないトマト抽出物の製造方法 |
| JP2024166969A Pending JP2025010139A (ja) | 2012-04-23 | 2024-09-26 | 抗高血圧症薬としてのトマト抽出物の使用及び水溶性の糖を含まないトマト抽出物の製造方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018211985A Pending JP2019038844A (ja) | 2012-04-23 | 2018-11-12 | 抗高血圧症薬としてのトマト抽出物の使用及び水溶性の糖を含まないトマト抽出物の製造方法 |
| JP2020156083A Pending JP2021008474A (ja) | 2012-04-23 | 2020-09-17 | 抗高血圧症薬としてのトマト抽出物の使用及び水溶性の糖を含まないトマト抽出物の製造方法 |
| JP2022165980A Pending JP2023009053A (ja) | 2012-04-23 | 2022-10-17 | 抗高血圧症薬としてのトマト抽出物の使用及び水溶性の糖を含まないトマト抽出物の製造方法 |
| JP2024166969A Pending JP2025010139A (ja) | 2012-04-23 | 2024-09-26 | 抗高血圧症薬としてのトマト抽出物の使用及び水溶性の糖を含まないトマト抽出物の製造方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20150132371A1 (enExample) |
| EP (1) | EP2844083B1 (enExample) |
| JP (5) | JP2015515493A (enExample) |
| CN (2) | CN104363774A (enExample) |
| AU (1) | AU2013252637B2 (enExample) |
| CA (1) | CA2881555C (enExample) |
| DK (1) | DK2844083T3 (enExample) |
| ES (1) | ES2692158T3 (enExample) |
| IN (1) | IN2014MN02392A (enExample) |
| NZ (1) | NZ630482A (enExample) |
| PL (1) | PL2844083T3 (enExample) |
| PT (1) | PT2844083T (enExample) |
| TR (1) | TR201815457T4 (enExample) |
| WO (1) | WO2013163057A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0819959D0 (en) * | 2008-10-31 | 2008-12-10 | Provexis Natural Products Ltd | Fruit extracts |
| PL2844083T3 (pl) | 2012-04-23 | 2018-12-31 | University Of Oslo | Zastosowanie ekstraktu pomidorowego jako środka przeciwdziałającego nadciśnieniu i proces do sporządzania rozpuszczalnego w wodzie ekstraktu pomidorowego bez cukru |
| GB201223365D0 (en) | 2012-12-24 | 2013-02-06 | Provexis Natural Products Ltd | Compositions |
| MX2019005054A (es) | 2016-11-02 | 2019-06-20 | Provexis Natural Products Ltd | Extracto de jitomate soluble en agua protege contra los efectos adversos de la contaminacion del aire. |
| CN109380728B (zh) * | 2018-10-17 | 2022-03-22 | 汤臣倍健股份有限公司 | 一种具有辅助降血压功效的组合物及保健食品 |
| TW202034936A (zh) * | 2019-02-15 | 2020-10-01 | 國立大學法人信州大學 | 具有降低血壓的作用之源自茄子的組成物 |
| CN110638902A (zh) * | 2019-09-30 | 2020-01-03 | 白冬平 | 番茄提取物在制备降血压药物中的应用及其降血压组合物 |
| DE102020001722A1 (de) | 2020-03-14 | 2021-09-16 | DÖHLER GmbH | Verfahren zur Herstellung eines aromabeladenen Gases, aromabeladenes Gas und Verwendung des aromabeladenen Gases |
| WO2022238727A1 (en) * | 2021-05-08 | 2022-11-17 | Momand Hossay | Methods for preparing white heirloom tomato-based compositions for skin lightening via enhanced glutathione, and associated compositions thereof |
| CN114617920B (zh) * | 2022-04-11 | 2023-10-13 | 汤臣倍健股份有限公司 | 一种具有改善记忆力功能的水溶性番茄提取物及其应用 |
| GB202208323D0 (en) * | 2022-06-07 | 2022-07-20 | Provexis Natural Products Ltd | Compostions |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6467173A (en) | 1987-09-04 | 1989-03-13 | Sanei Kagaku Kogyo Kk | Preparation of vegetable or fruit juices |
| JP2722670B2 (ja) * | 1989-05-30 | 1998-03-04 | ライオン株式会社 | 高血圧症予防用飲食品及びその製造方法 |
| JP2997358B2 (ja) | 1992-01-30 | 2000-01-11 | ポーラ化成工業株式会社 | 皮膚外用剤 |
| DK0656881T3 (da) | 1992-07-30 | 1999-06-23 | Cal Int Ltd | Ester og kombinationer af et organisk nitrat og et salicylat |
| US5502038A (en) | 1993-06-21 | 1996-03-26 | Medical Research Foundation Of Oregon | Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption |
| JP2905725B2 (ja) * | 1995-07-01 | 1999-06-14 | カゴメ株式会社 | トマト由来の食品組成物 |
| FR2759904B1 (fr) | 1997-02-25 | 2000-01-28 | Alma Heny Reza | Compositions a usage cosmetique et/ou pharmaceutique et/ou dermatologique et leurs procedes de fabrication |
| DE19720767A1 (de) | 1997-05-07 | 1998-11-12 | Protekum Umweltinstitut Gmbh O | Pharmazeutisches Produkt, insbesondere zur Therapie und Prophylaxe von Herz-Kreislauf-Erkrankungen |
| GB9808796D0 (en) | 1998-04-24 | 1998-06-24 | Rowett Research Services Limit | Antithrombotic agents |
| DE69907342T2 (de) | 1998-09-02 | 2004-03-25 | Unilever N.V. | Mit beta-cyclocitral angereicherte Tomatenprodukte |
| AU5965399A (en) | 1998-10-12 | 2000-05-01 | Andreas Bockelmann | Pharmaceutically active composition |
| CN1352941A (zh) | 2000-11-11 | 2002-06-12 | 吉建军 | 亚油酸胶囊 |
| WO2002090386A2 (en) | 2001-05-04 | 2002-11-14 | Ato B.V. | Regulatory protein involved in pectin modification |
| DE10300049A1 (de) | 2003-01-03 | 2004-07-15 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen, die Faktor VIIa inhibieren |
| ITMI20020632A1 (it) | 2002-03-27 | 2003-09-29 | Indena Spa | Processo per la preparazione di estratti di pomodoro ad elevato contenuto di licopene |
| EP1559421B1 (en) | 2002-11-06 | 2016-07-27 | Kao Corporation | Blood circulation promoting agent |
| JP4684893B2 (ja) | 2003-03-27 | 2011-05-18 | ユニジェン インク． | 炎症性及び血液循環疾患の治療及び予防活性を示す、竹抽出物並びにそれから分離された化合物を含有する組成物 |
| JP4571783B2 (ja) | 2003-04-14 | 2010-10-27 | 林原 健 | 抗微生物剤 |
| US20040223962A1 (en) | 2003-05-07 | 2004-11-11 | Riordan Neil H. | Method and composition for preventing or reducing edema, deep vein thrombosis and/or pulmonary embolism |
| EP1481669A1 (en) | 2003-05-30 | 2004-12-01 | Yamanouchi Pharmaceutical Co. Ltd. | Use of polyhydroxy phenols and polyphenols for modulating p-selectin activity |
| ES2322757T3 (es) | 2003-08-21 | 2009-06-26 | Nestec S.A. | Concentrado natural de licopeno y procedimiento de obtencion. |
| JP2004137287A (ja) * | 2003-12-08 | 2004-05-13 | Kao Corp | 高血圧症予防・治療剤 |
| FR2871378B1 (fr) | 2004-06-15 | 2007-03-30 | Seppic Sa | Nouveau medicament a base de flavanois et de leurs derives et son utilisation pour obtenir un medicament destine a la prevention de la restenose et de la maladie atheromateuse chez les patients coronariens |
| EP1640001A1 (en) | 2004-09-24 | 2006-03-29 | New Pharma Investments Holding | Composition against cardiovascular diseases |
| CN100488535C (zh) | 2004-12-09 | 2009-05-20 | 郭富凤 | 一种番茄红素混合物 |
| US7419960B2 (en) | 2005-01-07 | 2008-09-02 | Hong Kong Baptist University | Hemiterpene glycosides with anti-platelet aggregation activities from Ilex pubescens |
| JP2006193435A (ja) | 2005-01-11 | 2006-07-27 | Kagome Co Ltd | 疲労改善剤 |
| GB0502985D0 (en) * | 2005-02-14 | 2005-03-16 | Provexis Ltd | Therapeutic uses of tomato extracts |
| WO2006094120A2 (en) | 2005-03-02 | 2006-09-08 | The Regents Of The University Of California | Treatment for embolic stroke |
| JP4260158B2 (ja) | 2005-07-07 | 2009-04-30 | 長谷川香料株式会社 | トマトジュース濃縮物の製造方法およびトマト風味組成物 |
| US20070082071A1 (en) | 2005-10-07 | 2007-04-12 | Willimann John A | Composition for controlling the respiratory effects of inhaled pollutants & allergens |
| AT503521A1 (de) | 2006-05-05 | 2007-11-15 | Omnica Gmbh | Verwendung eines extraktes von kiwi-frucht |
| GB0610790D0 (en) | 2006-06-02 | 2006-07-12 | Provexis Natural Products Ltd | Therapeutic uses of tomato extracts |
| US20080009449A1 (en) | 2006-07-07 | 2008-01-10 | Kailash Prasad | Lignan complex derived from flax seed used for treatment of hypercholesterolemic atherosclerosis |
| SG191445A1 (en) | 2006-12-22 | 2013-07-31 | Univ Johns Hopkins | Anti-cholesterolemic compounds and methods of use |
| US8759327B2 (en) | 2007-04-16 | 2014-06-24 | The Regents Of The University Of Michigan | Plasminogen activator inhibitor-1 inhibitors and methods of use thereof to modulate lipid metabolism |
| EP2036568A1 (en) | 2007-09-12 | 2009-03-18 | Nestec S.A. | Wolfberries and inflammation |
| JP2009240191A (ja) | 2008-03-31 | 2009-10-22 | Shimizu Shoko Kaigisho | 光照射によるリグナン類・リグニン類合成系遺伝子の発現増強 |
| GB0819958D0 (en) | 2008-10-31 | 2008-12-10 | Provexis Natural Products Ltd | Therapeutic compositions |
| GB0819959D0 (en) * | 2008-10-31 | 2008-12-10 | Provexis Natural Products Ltd | Fruit extracts |
| CA2785581A1 (en) | 2009-12-24 | 2011-06-30 | Stanley Kubow | Compositions and methods for preventing and treating diseases and environmentally induced health disorders |
| JP6058872B2 (ja) * | 2010-01-18 | 2017-01-11 | キッコーマン株式会社 | 抗ストレス作用を有するｇａｂａ高含有トマト由来組成物 |
| PL2844083T3 (pl) | 2012-04-23 | 2018-12-31 | University Of Oslo | Zastosowanie ekstraktu pomidorowego jako środka przeciwdziałającego nadciśnieniu i proces do sporządzania rozpuszczalnego w wodzie ekstraktu pomidorowego bez cukru |
| GB201223365D0 (en) | 2012-12-24 | 2013-02-06 | Provexis Natural Products Ltd | Compositions |
| MX2019005054A (es) | 2016-11-02 | 2019-06-20 | Provexis Natural Products Ltd | Extracto de jitomate soluble en agua protege contra los efectos adversos de la contaminacion del aire. |
-
2013
- 2013-04-22 PL PL13719356T patent/PL2844083T3/pl unknown
- 2013-04-22 CA CA2881555A patent/CA2881555C/en active Active
- 2013-04-22 DK DK13719356.1T patent/DK2844083T3/en active
- 2013-04-22 EP EP13719356.1A patent/EP2844083B1/en active Active
- 2013-04-22 IN IN2392MUN2014 patent/IN2014MN02392A/en unknown
- 2013-04-22 WO PCT/US2013/037524 patent/WO2013163057A1/en not_active Ceased
- 2013-04-22 TR TR2018/15457T patent/TR201815457T4/tr unknown
- 2013-04-22 JP JP2015509056A patent/JP2015515493A/ja active Pending
- 2013-04-22 AU AU2013252637A patent/AU2013252637B2/en active Active
- 2013-04-22 PT PT13719356T patent/PT2844083T/pt unknown
- 2013-04-22 CN CN201380031408.9A patent/CN104363774A/zh not_active Withdrawn
- 2013-04-22 CN CN201710610558.5A patent/CN107397830A/zh active Pending
- 2013-04-22 US US14/395,884 patent/US20150132371A1/en not_active Abandoned
- 2013-04-22 NZ NZ630482A patent/NZ630482A/en unknown
- 2013-04-22 ES ES13719356.1T patent/ES2692158T3/es active Active
-
2017
- 2017-12-21 US US15/850,107 patent/US10864241B2/en active Active
-
2018
- 2018-11-12 JP JP2018211985A patent/JP2019038844A/ja active Pending
-
2020
- 2020-09-17 JP JP2020156083A patent/JP2021008474A/ja active Pending
- 2020-11-12 US US17/096,086 patent/US20210236578A1/en not_active Abandoned
-
2022
- 2022-10-17 JP JP2022165980A patent/JP2023009053A/ja active Pending
-
2024
- 2024-09-26 JP JP2024166969A patent/JP2025010139A/ja active Pending
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