JP2015505966A5 - - Google Patents
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- Publication number
- JP2015505966A5 JP2015505966A5 JP2014546147A JP2014546147A JP2015505966A5 JP 2015505966 A5 JP2015505966 A5 JP 2015505966A5 JP 2014546147 A JP2014546147 A JP 2014546147A JP 2014546147 A JP2014546147 A JP 2014546147A JP 2015505966 A5 JP2015505966 A5 JP 2015505966A5
- Authority
- JP
- Japan
- Prior art keywords
- well
- sample
- cell
- tumor cells
- circulating tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 26
- 238000000034 method Methods 0.000 claims 19
- 208000005443 Circulating Neoplastic Cells Diseases 0.000 claims 13
- 238000004458 analytical method Methods 0.000 claims 10
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 7
- 102000011782 Keratins Human genes 0.000 claims 7
- 108010076876 Keratins Proteins 0.000 claims 7
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 7
- 239000000758 substrate Substances 0.000 claims 7
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 5
- 238000012512 characterization method Methods 0.000 claims 4
- 238000003384 imaging method Methods 0.000 claims 4
- 239000008280 blood Substances 0.000 claims 3
- 210000004369 blood Anatomy 0.000 claims 3
- 239000003153 chemical reaction reagent Substances 0.000 claims 3
- 238000001514 detection method Methods 0.000 claims 3
- 238000004393 prognosis Methods 0.000 claims 3
- FWBHETKCLVMNFS-UHFFFAOYSA-N 4',6-Diamino-2-phenylindol Chemical compound C1=CC(C(=N)N)=CC=C1C1=CC2=CC=C(C(N)=N)C=C2N1 FWBHETKCLVMNFS-UHFFFAOYSA-N 0.000 claims 2
- 239000002771 cell marker Substances 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 238000013523 data management Methods 0.000 claims 2
- 238000013500 data storage Methods 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 239000011521 glass Substances 0.000 claims 2
- 239000003550 marker Substances 0.000 claims 2
- 230000004987 nonapoptotic effect Effects 0.000 claims 2
- 230000004043 responsiveness Effects 0.000 claims 2
- 239000002356 single layer Substances 0.000 claims 2
- 238000000116 DAPI staining Methods 0.000 claims 1
- 230000001464 adherent effect Effects 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 238000000423 cell based assay Methods 0.000 claims 1
- 239000002458 cell surface marker Substances 0.000 claims 1
- 238000009104 chemotherapy regimen Methods 0.000 claims 1
- 239000006059 cover glass Substances 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 230000005284 excitation Effects 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 238000005286 illumination Methods 0.000 claims 1
- 238000011269 treatment regimen Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161568793P | 2011-12-09 | 2011-12-09 | |
| US61/568,793 | 2011-12-09 | ||
| PCT/US2012/068586 WO2013086428A1 (en) | 2011-12-09 | 2012-12-07 | Apparatus, system and method for identifying circulating tumor cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015505966A JP2015505966A (ja) | 2015-02-26 |
| JP2015505966A5 true JP2015505966A5 (enExample) | 2016-03-31 |
Family
ID=48574948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014546147A Pending JP2015505966A (ja) | 2011-12-09 | 2012-12-07 | 循環腫瘍細胞を特定するための装置、システム、及び方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20140329917A1 (enExample) |
| EP (1) | EP2788773A4 (enExample) |
| JP (1) | JP2015505966A (enExample) |
| KR (1) | KR20150008842A (enExample) |
| CN (1) | CN104428677A (enExample) |
| AU (1) | AU2012347526A1 (enExample) |
| BR (1) | BR112014013956A8 (enExample) |
| CA (1) | CA2858689A1 (enExample) |
| EA (1) | EA201491140A1 (enExample) |
| HK (1) | HK1201916A1 (enExample) |
| IL (1) | IL233007A0 (enExample) |
| MX (1) | MX2014006884A (enExample) |
| SG (1) | SG11201403041TA (enExample) |
| WO (1) | WO2013086428A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2784011T3 (es) | 2002-10-16 | 2020-09-21 | Streck Inc | Procedimiento y dispositivo para recoger y preservar las células para su análisis |
| US11634747B2 (en) | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
| EP3290530B1 (en) | 2009-02-18 | 2020-09-02 | Streck Inc. | Preservation of cell-free nucleic acids |
| EP2491395B1 (en) | 2009-10-21 | 2015-09-16 | The Scripps Research Institute | Method of using non-rare cells to detect rare cells |
| WO2012151391A2 (en) | 2011-05-04 | 2012-11-08 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
| US9396532B2 (en) * | 2012-11-15 | 2016-07-19 | Siemens Healthcare Diagnostics, Inc. | Cell feature-based automatic circulating tumor cell detection |
| EP4136972A1 (en) | 2013-07-24 | 2023-02-22 | Streck, Inc. | Compositions and methods for stabilizing circulating tumor cells |
| WO2015017046A1 (en) * | 2013-07-31 | 2015-02-05 | The Regents Of The University Of California | Fluorescent imaging using a flatbed scanner |
| EP3060680B1 (en) * | 2013-10-21 | 2019-02-27 | The General Hospital Corporation | Methods relating to circulating tumor cell clusters and the treatment of cancer |
| US20160011198A1 (en) * | 2014-01-27 | 2016-01-14 | Epic Sciences, Inc. | Detection of prostate specific membrane antigen (psma) expression on circulating tumor cells (ctc) |
| WO2015112955A1 (en) | 2014-01-27 | 2015-07-30 | Epic Sciences, Inc. | Circulating tumor cell diagnostics for prostate cancer biomarkers |
| EP3100052B1 (en) * | 2014-01-30 | 2021-03-10 | Epic Sciences, Inc. | Circulating tumor cell diagnostics for biomarkers predictive of resistance to androgen receptor (ar) targeted therapies |
| EA201691682A1 (ru) | 2014-02-21 | 2017-02-28 | Эпик Сайенсиз, Инк. | Способы анализирования редких циркулирующих в крови клеток |
| CN104062428B (zh) * | 2014-07-09 | 2016-08-17 | 郑勤 | 一种检测循环肿瘤细胞的试剂盒 |
| CN113528663A (zh) * | 2014-12-10 | 2021-10-22 | 得克萨斯州大学系统董事会 | 使用基因组特异性探针的循环肿瘤和肿瘤干细胞检测 |
| US20160178630A1 (en) * | 2014-12-18 | 2016-06-23 | Creatv Microtech, Inc. | Methods for predicting overall survival of cancer patients based on numbers of circulating tumor cells |
| WO2016121574A1 (ja) * | 2015-01-29 | 2016-08-04 | コニカミノルタ株式会社 | 相互作用する分子を有する血中細胞の同時検出方法 |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| EP3286565B1 (en) * | 2015-04-21 | 2025-01-15 | Genentech, Inc. | Compositions and methods for prostate cancer analysis |
| JP2018518689A (ja) * | 2015-05-14 | 2018-07-12 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイＴｈｅ Ｂｏａｒｄ Ｏｆ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｉｌｌｉｎｏｉｓ | バイオマーカーとして循環腫瘍細胞を使用するがん治療の有効性をモニタリングするための方法 |
| WO2016207986A1 (ja) | 2015-06-24 | 2016-12-29 | 株式会社日立製作所 | 検査システム、検査装置、及び検査方法 |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| US10641689B2 (en) * | 2016-07-25 | 2020-05-05 | Optnics Precision Co., Ltd. | Method of preparing glass slide specimen of cells |
| WO2018022991A1 (en) | 2016-07-29 | 2018-02-01 | Streck, Inc. | Suspension composition for hematology analysis control |
| JPWO2018116465A1 (ja) * | 2016-12-22 | 2019-10-24 | 日立化成株式会社 | Ｈｅｒ２陽性癌細胞の検出方法 |
| US9738937B1 (en) | 2017-03-31 | 2017-08-22 | Cellmax, Ltd. | Identifying candidate cells using image analysis |
| IT201700085439A1 (it) * | 2017-07-26 | 2019-01-26 | Tethis S P A | Metodo di immobilizzazione di campioni biologici a scopo analitico e diagnostico |
| US12378543B2 (en) | 2017-10-19 | 2025-08-05 | Streck Llc | Compositions for hemolysis and coagulation regulation and stabilization of extracellular vesicles |
| JP6485576B2 (ja) * | 2018-04-19 | 2019-03-20 | 日立化成株式会社 | 標準細胞液 |
| CN109887542A (zh) * | 2019-02-12 | 2019-06-14 | 嘉兴海云惠智医疗科技有限公司 | 一种基于云计算的肿瘤个体化基因检测智能解读系统 |
| CN110146704A (zh) * | 2019-03-28 | 2019-08-20 | 苏州举健生物科技有限公司 | 一种基于循环肿瘤细胞的用药及病理检测数据系统 |
| JP2021110664A (ja) * | 2020-01-14 | 2021-08-02 | 学校法人杏林学園 | 癌被験体の予後を予測する方法 |
| CN111323362A (zh) * | 2020-03-17 | 2020-06-23 | 宁波江丰生物信息技术有限公司 | 一种基于荧光切片的循环肿瘤细胞检测系统及检测方法 |
| CN114092934A (zh) * | 2020-07-31 | 2022-02-25 | 骏实生物科技(上海)有限公司 | 循环肿瘤细胞的分类方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3830721A1 (de) * | 1988-09-09 | 1990-03-22 | Michael Dr Menton | In labors, insbesondere in medizinischen labors, zu verwendender objekttraeger |
| CN2265982Y (zh) * | 1996-05-20 | 1997-10-29 | 中国农业大学 | 平底方槽型细胞显微操作载片 |
| US8192994B2 (en) * | 1998-02-10 | 2012-06-05 | Angros Lee H | Method of applying a biological specimen to an analytic plate |
| JP2002526785A (ja) * | 1998-08-07 | 2002-08-20 | バイオジェネックス ラボラトリーズ | 疎水性防壁によって規定された反応区域を有するスライド |
| CN2377532Y (zh) * | 1999-06-10 | 2000-05-10 | 中国人民解放军第二军医大学 | 微量荧光细胞计数板 |
| US20020187485A1 (en) * | 2000-10-25 | 2002-12-12 | Jakobsen Mogens Hausteen | Open substrate platforms suitable for analysis of biomolecules |
| US7943093B2 (en) * | 2001-12-12 | 2011-05-17 | Erie Scientific Company | Cover slip |
| US20070009389A1 (en) * | 2005-07-08 | 2007-01-11 | Antti Seppo | Slide deposition chamber |
| EP1984030B1 (en) * | 2006-01-30 | 2013-05-08 | The Scripps Research Institute | Methods for detection of circulating tumor cells and methods of diagnosis of cancer in a mammalian subject |
| US8244021B2 (en) * | 2006-12-20 | 2012-08-14 | Ventana Medical Systems, Inc. | Quantitative, multispectral image analysis of tissue specimens stained with quantum dots |
| US20100184629A1 (en) * | 2007-06-05 | 2010-07-22 | Nanopoint, Inc. | Cell tray systems and methods |
| CN201184866Y (zh) * | 2008-02-26 | 2009-01-21 | 强实贸易(上海)有限公司 | 定量细胞计数系统装置 |
| EP2350617B1 (en) * | 2008-10-21 | 2018-01-10 | ChemoMetec A/S | Fluorescence imaging apparatus and method |
| CA2788245A1 (en) * | 2010-01-27 | 2011-08-04 | Duke University | Biomarkers for circulating tumor cells |
-
2012
- 2012-12-07 BR BR112014013956A patent/BR112014013956A8/pt not_active Application Discontinuation
- 2012-12-07 WO PCT/US2012/068586 patent/WO2013086428A1/en not_active Ceased
- 2012-12-07 US US14/363,290 patent/US20140329917A1/en not_active Abandoned
- 2012-12-07 JP JP2014546147A patent/JP2015505966A/ja active Pending
- 2012-12-07 EA EA201491140A patent/EA201491140A1/ru unknown
- 2012-12-07 MX MX2014006884A patent/MX2014006884A/es unknown
- 2012-12-07 KR KR20147018924A patent/KR20150008842A/ko not_active Withdrawn
- 2012-12-07 EP EP12855719.6A patent/EP2788773A4/en not_active Withdrawn
- 2012-12-07 HK HK15102251.3A patent/HK1201916A1/xx unknown
- 2012-12-07 SG SG11201403041TA patent/SG11201403041TA/en unknown
- 2012-12-07 CN CN201280069331.XA patent/CN104428677A/zh active Pending
- 2012-12-07 AU AU2012347526A patent/AU2012347526A1/en not_active Abandoned
- 2012-12-07 CA CA2858689A patent/CA2858689A1/en not_active Abandoned
-
2014
- 2014-06-08 IL IL233007A patent/IL233007A0/en unknown
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