JP2015503560A5 - - Google Patents

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Publication number
JP2015503560A5
JP2015503560A5 JP2014550335A JP2014550335A JP2015503560A5 JP 2015503560 A5 JP2015503560 A5 JP 2015503560A5 JP 2014550335 A JP2014550335 A JP 2014550335A JP 2014550335 A JP2014550335 A JP 2014550335A JP 2015503560 A5 JP2015503560 A5 JP 2015503560A5
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JP
Japan
Prior art keywords
composition
solid dispersion
hcv
solid
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2014550335A
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English (en)
Japanese (ja)
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JP2015503560A (ja
JP5781706B2 (ja
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Priority claimed from PCT/US2012/070349 external-priority patent/WO2013101550A1/en
Publication of JP2015503560A publication Critical patent/JP2015503560A/ja
Publication of JP2015503560A5 publication Critical patent/JP2015503560A5/ja
Application granted granted Critical
Publication of JP5781706B2 publication Critical patent/JP5781706B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2014550335A 2011-12-29 2012-12-18 Ｈｃｖ阻害剤を含む固体組成物 Active JP5781706B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161581146P 2011-12-29 2011-12-29
US61/581,146 2011-12-29
US201261645696P 2012-05-11 2012-05-11
US61/645,696 2012-05-11
PCT/US2012/070349 WO2013101550A1 (en) 2011-12-29 2012-12-18 Solid compositions comprising an hcv inhibitor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015140513A Division JP2015227352A (ja) 2011-12-29 2015-07-14 Ｈｃｖ阻害剤を含む固体組成物

Publications (3)

Publication Number Publication Date
JP2015503560A JP2015503560A (ja) 2015-02-02
JP2015503560A5 true JP2015503560A5 (enExample) 2015-03-12
JP5781706B2 JP5781706B2 (ja) 2015-09-24

Family

ID=47470243

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014550335A Active JP5781706B2 (ja) 2011-12-29 2012-12-18 Ｈｃｖ阻害剤を含む固体組成物
JP2015140513A Pending JP2015227352A (ja) 2011-12-29 2015-07-14 Ｈｃｖ阻害剤を含む固体組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015140513A Pending JP2015227352A (ja) 2011-12-29 2015-07-14 Ｈｃｖ阻害剤を含む固体組成物

Country Status (9)

Country Link
US (1) US20130172239A1 (enExample)
EP (2) EP2907505A3 (enExample)
JP (2) JP5781706B2 (enExample)
CN (1) CN104010631B (enExample)
CA (1) CA2857339C (enExample)
DE (1) DE212012000197U1 (enExample)
HK (1) HK1201186A1 (enExample)
MX (1) MX2014008008A (enExample)
WO (1) WO2013101550A1 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2840242C (en) 2011-09-16 2019-03-26 Gilead Sciences, Inc. Methods for treating hcv
PL2635588T3 (pl) 2011-11-16 2015-10-30 Gilead Pharmasset Llc Skondensowane imidazoliloimidazole jako związki antywirusowe
US9326973B2 (en) 2012-01-13 2016-05-03 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
CN104363898A (zh) * 2012-05-07 2015-02-18 百时美施贵宝爱尔兰控股公司 [(1s)-1-{[(2s,4r)-4-(7-氯-4-甲氧基异喹啉-1-基氧基)-2-({(1r,2s)-1-[(环丙基磺酰基)氨甲酰基]-2-乙烯基环丙基}氨甲酰基)吡咯烷-1-基]羰基}-2,2-二甲基丙基]氨基甲酸1,1-二甲基乙基酯的口服固体给药制剂
US8969588B2 (en) * 2012-06-05 2015-03-03 Gilead Pharmasset Llc Solid forms of an antiviral compound
TW201446286A (zh) * 2013-01-31 2014-12-16 Gilead Pharmasset Llc 抗病毒化合物之固態分散調製劑
KR20200060782A (ko) * 2013-01-31 2020-06-01 길리애드 파마셋 엘엘씨 두 항바이러스 화합물의 병용 제형물
CA2903831A1 (en) * 2013-03-15 2014-09-25 Boehringer Ingelheim International Gmbh Solid oral dosage formulation of hcv inhibitor in the amorphous state
US20140271855A1 (en) * 2013-03-15 2014-09-18 Achillion Pharmaceuticals Inc. Sovaprevir tablets
CN105705511A (zh) 2013-04-12 2016-06-22 艾其林医药公司 用于治疗hcv的氘化核苷前药
US20150023913A1 (en) 2013-07-02 2015-01-22 Bristol-Myers Squibb Company Hepatitis C Virus Inhibitors
US9717712B2 (en) 2013-07-02 2017-08-01 Bristol-Myers Squibb Company Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus
WO2015009744A1 (en) 2013-07-17 2015-01-22 Bristol-Myers Squibb Company Combinations comprising biphenyl derivatives for use in the treatment of hcv
EP3650014B1 (en) 2013-08-27 2021-10-06 Gilead Pharmasset LLC Combination formulation of two antiviral compounds
CA2937942A1 (en) * 2014-02-05 2015-08-13 Merck Sharp & Dohme Corp. Fixed-dose combinations of antiviral compounds
US20160339074A1 (en) * 2014-02-05 2016-11-24 Merck Sharp & Dohme Corp. Pharmaceutical composition of selective hcv ns3/4a inhibitors
EP3102188A4 (en) * 2014-02-05 2017-07-12 Merck Sharp & Dohme Corp. Novel disintegration systems for pharmaceutical dosage forms
CN106163529A (zh) * 2014-04-03 2016-11-23 桑多斯股份公司 包含无定形索非布韦的固体组合物
TWI721947B (zh) 2014-06-11 2021-03-21 美商基利法瑪席特有限責任公司 抗病毒化合物的固態形式
WO2016038542A2 (en) * 2014-09-10 2016-03-17 Mylan Laboratories Limited Polymorphic forms of sofosbuvir
WO2016075588A1 (en) * 2014-11-11 2016-05-19 Sun Pharmaceutical Industries Limited Stable amorphous daclatasvir dihydrochloride
EP3256104A1 (en) * 2015-02-13 2017-12-20 Sandoz AG Pharmaceutical compositions comprising ledipasvir and sofosbuvir
WO2016145269A1 (en) 2015-03-12 2016-09-15 Teva Pharmaceuticals International Gmbh Solid state forms ledipasvir and processes for preparation of ledipasvir
WO2017021904A1 (en) * 2015-08-03 2017-02-09 Laurus Labs Private Limited Daclatasvir free base and process for the preparation thereof
US20180228826A1 (en) * 2015-08-04 2018-08-16 Merck Sharp & Dohme Corp. Fixed-dose combinations of antiviral compounds
US20180228827A1 (en) * 2015-08-04 2018-08-16 Merck Sharp & Dohme Corp. Fixed-dose combinations of antiviral compounds
WO2017023716A1 (en) * 2015-08-04 2017-02-09 Merck Sharp & Dohme Corp. Fixed-dose combinations of antiviral compounds
WO2017023713A1 (en) * 2015-08-04 2017-02-09 Merck Sharp & Dohme Corp. Methods for making pharmaceutical solid dosage forms of spray-dried dispersions
US10617675B2 (en) 2015-08-06 2020-04-14 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
EP3359199A1 (en) 2015-10-07 2018-08-15 Sandoz AG Solid pharmaceutical composition comprising amorphous sofosbuvir
WO2017072714A1 (en) 2015-10-30 2017-05-04 Lupin Limited Stable ledipasvir premix and process of preparation thereof
BR102017011025A2 (pt) * 2016-06-02 2017-12-19 Gilead Pharmasset Llc Formulation of combination of three antiviral compounds
BR112019002729A2 (pt) 2016-08-12 2019-05-14 Sandoz Ag composição farmacêutica sólida e processo para preparar uma composição farmacêutica sólida
WO2018078536A1 (en) 2016-10-26 2018-05-03 Lupin Limited Stable solid dispersion of sofosbuvir and process for preparation thereof
CN106727516A (zh) * 2017-01-10 2017-05-31 山东省立医院 一种治疗丙型肝炎的药物组合物
WO2019134971A1 (en) * 2018-01-04 2019-07-11 Sandoz Ag Encapsulated particles comprising a pharmaceutically active ingredient
US11378965B2 (en) 2018-11-15 2022-07-05 Toyota Research Institute, Inc. Systems and methods for controlling a vehicle based on determined complexity of contextual environment
CN113209087B (zh) * 2020-02-05 2023-11-07 歌礼药业（浙江）有限公司 一种抑制冠状病毒的药物组合物及其用途
US20220175812A1 (en) 2020-12-03 2022-06-09 Battelle Memorial Institute Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
JP2024516108A (ja) 2021-04-07 2024-04-12 バテル・メモリアル・インスティテュート 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術
NL2028762B1 (en) * 2021-07-16 2023-01-23 Seranovo Holding B V Micelle-generating formulations for enhanced bioavailability
KR102842201B1 (ko) * 2023-09-19 2025-08-06 한국해양과학기술원 Lng 추진 선박용 이산화탄소 액화 시스템 및 방법
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
US12441996B2 (en) 2023-12-08 2025-10-14 Battelle Memorial Institute Use of DNA origami nanostructures for molecular information based data storage systems

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003063822A2 (en) * 2002-02-01 2003-08-07 Pfizer Products Inc. Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus
ZA200700030B (en) * 2004-06-08 2009-06-24 Vertex Pharma Pharmaceutical compositions
CN101494979A (zh) * 2006-03-20 2009-07-29 沃泰克斯药物股份有限公司 药物组合物
US7964580B2 (en) * 2007-03-30 2011-06-21 Pharmasset, Inc. Nucleoside phosphoramidate prodrugs
US20090143423A1 (en) * 2007-10-19 2009-06-04 Abbott Gmbh & Co. Kg Solid dispersion product containing n-aryl urea-based compound
JP2011530532A (ja) * 2008-08-07 2011-12-22 シェーリング コーポレイション 固体分子分散物中のｈｃｖプロテアーゼインヒビターの薬学的処方物
EP3150596A1 (en) * 2009-02-27 2017-04-05 Janssen Pharmaceuticals, Inc. Amorphous salt of a macrocyclic inhibitor of hcv
MX363732B (es) * 2009-05-13 2019-04-01 Gilead Pharmasset Llc Star Compuestos antivirales.
US8937150B2 (en) * 2009-06-11 2015-01-20 Abbvie Inc. Anti-viral compounds
DK2368890T3 (da) * 2009-06-11 2013-07-22 Abbvie Bahamas Ltd Hepatitis C-virusinhibitorer
US8415374B2 (en) * 2009-10-12 2013-04-09 Bristol-Myers Squibb Company Combinations of hepatitis C virus inhibitors
NZ605440A (en) * 2010-06-10 2014-05-30 Abbvie Bahamas Ltd Solid compositions comprising an hcv inhibitor
TW201446286A (zh) * 2013-01-31 2014-12-16 Gilead Pharmasset Llc 抗病毒化合物之固態分散調製劑

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