JP2015503560A5 - - Google Patents
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- Publication number
- JP2015503560A5 JP2015503560A5 JP2014550335A JP2014550335A JP2015503560A5 JP 2015503560 A5 JP2015503560 A5 JP 2015503560A5 JP 2014550335 A JP2014550335 A JP 2014550335A JP 2014550335 A JP2014550335 A JP 2014550335A JP 2015503560 A5 JP2015503560 A5 JP 2015503560A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- solid dispersion
- hcv
- solid
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161581146P | 2011-12-29 | 2011-12-29 | |
| US61/581,146 | 2011-12-29 | ||
| US201261645696P | 2012-05-11 | 2012-05-11 | |
| US61/645,696 | 2012-05-11 | ||
| PCT/US2012/070349 WO2013101550A1 (en) | 2011-12-29 | 2012-12-18 | Solid compositions comprising an hcv inhibitor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015140513A Division JP2015227352A (ja) | 2011-12-29 | 2015-07-14 | Hcv阻害剤を含む固体組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015503560A JP2015503560A (ja) | 2015-02-02 |
| JP2015503560A5 true JP2015503560A5 (enExample) | 2015-03-12 |
| JP5781706B2 JP5781706B2 (ja) | 2015-09-24 |
Family
ID=47470243
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014550335A Expired - Fee Related JP5781706B2 (ja) | 2011-12-29 | 2012-12-18 | Hcv阻害剤を含む固体組成物 |
| JP2015140513A Pending JP2015227352A (ja) | 2011-12-29 | 2015-07-14 | Hcv阻害剤を含む固体組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015140513A Pending JP2015227352A (ja) | 2011-12-29 | 2015-07-14 | Hcv阻害剤を含む固体組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20130172239A1 (enExample) |
| EP (2) | EP2797586A1 (enExample) |
| JP (2) | JP5781706B2 (enExample) |
| CN (1) | CN104010631B (enExample) |
| CA (1) | CA2857339C (enExample) |
| DE (1) | DE212012000197U1 (enExample) |
| HK (1) | HK1201186A1 (enExample) |
| MX (1) | MX2014008008A (enExample) |
| WO (1) | WO2013101550A1 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2709613T2 (sl) | 2011-09-16 | 2020-12-31 | Gilead Pharmasset LLC c/o Gilead Sciences, Inc. | Postopki za zdravljenje HCV |
| PT2907816T (pt) | 2011-11-16 | 2018-10-18 | Gilead Pharmasset Llc | Imidazolilimidazóis condensados como compostos antivirais |
| US9326973B2 (en) | 2012-01-13 | 2016-05-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| WO2013169577A1 (en) * | 2012-05-07 | 2013-11-14 | Bristol-Myers Squibb Company | Oral solid dosage formulation of 1,1-dimethylethyl [(1s)-1-{[(2s,4r)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-({(1r,2s)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}carbamoyl)pyrrolidin-1-yl]carbonyl}-2,2-dimethylpropyl]carbamate |
| US8969588B2 (en) * | 2012-06-05 | 2015-03-03 | Gilead Pharmasset Llc | Solid forms of an antiviral compound |
| NZ729172A (en) * | 2013-01-31 | 2018-06-29 | Gilead Pharmasset Llc | Combination formulation of two antiviral compounds |
| TW201446286A (zh) * | 2013-01-31 | 2014-12-16 | Gilead Pharmasset Llc | 抗病毒化合物之固態分散調製劑 |
| CN105228593B (zh) * | 2013-03-15 | 2018-08-28 | 勃林格殷格翰国际有限公司 | 呈无定形状态的hcv抑制剂的固体口服剂型 |
| EP2968171A1 (en) * | 2013-03-15 | 2016-01-20 | Achillion Pharmaceuticals, Inc. | Sovaprevir tablets |
| BR112015025766A2 (pt) | 2013-04-12 | 2017-10-17 | Achillion Pharmaceuticals Inc | derivado de nucleosídeo altamente ativo para o tratamento de hcv |
| US9717712B2 (en) | 2013-07-02 | 2017-08-01 | Bristol-Myers Squibb Company | Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus |
| US20150023913A1 (en) | 2013-07-02 | 2015-01-22 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| CN105530933B (zh) | 2013-07-17 | 2018-12-11 | 百时美施贵宝公司 | 用于治疗hcv的包含联苯衍生物的组合产品 |
| JP2016529293A (ja) * | 2013-08-27 | 2016-09-23 | ギリアド ファーマセット エルエルシー | 2つの抗ウイルス化合物の組合せ製剤 |
| US20160346198A1 (en) * | 2014-02-05 | 2016-12-01 | Merck Sharp & Dohme Corp. | Novel disintegration systems for pharmaceutical dosage forms |
| EP3102210A4 (en) * | 2014-02-05 | 2017-10-11 | Merck Sharp & Dohme Corp. | Pharmaceutical composition of selective hcv ns3/4a inhibitors |
| CA2937942A1 (en) * | 2014-02-05 | 2015-08-13 | Merck Sharp & Dohme Corp. | Fixed-dose combinations of antiviral compounds |
| CA2943574A1 (en) * | 2014-04-03 | 2015-10-08 | Sandoz Ag | Solid composition comprising amorphous sofosbuvir |
| TWI721947B (zh) | 2014-06-11 | 2021-03-21 | 美商基利法瑪席特有限責任公司 | 抗病毒化合物的固態形式 |
| WO2016038542A2 (en) * | 2014-09-10 | 2016-03-17 | Mylan Laboratories Limited | Polymorphic forms of sofosbuvir |
| WO2016075588A1 (en) * | 2014-11-11 | 2016-05-19 | Sun Pharmaceutical Industries Limited | Stable amorphous daclatasvir dihydrochloride |
| WO2016128453A1 (en) * | 2015-02-13 | 2016-08-18 | Sandoz Ag | Pharmaceutical compositions comprising ledipasvir and sofosbuvir |
| WO2016145269A1 (en) | 2015-03-12 | 2016-09-15 | Teva Pharmaceuticals International Gmbh | Solid state forms ledipasvir and processes for preparation of ledipasvir |
| WO2017021904A1 (en) * | 2015-08-03 | 2017-02-09 | Laurus Labs Private Limited | Daclatasvir free base and process for the preparation thereof |
| US20180228828A1 (en) * | 2015-08-04 | 2018-08-16 | Merck Sharp & Dohme Corp. | Fixed-dose combinations of antiviral compounds |
| WO2017023714A1 (en) * | 2015-08-04 | 2017-02-09 | Merck Sharp & Dohme Corp. | Fixed-dose combinations of antiviral compounds |
| US20180221282A1 (en) * | 2015-08-04 | 2018-08-09 | Merck Sharp & Dohme Corp. | Methods for making pharmaceutical solid dosage forms of spray-dried dispersions |
| US20180228827A1 (en) * | 2015-08-04 | 2018-08-16 | Merck Sharp & Dohme Corp. | Fixed-dose combinations of antiviral compounds |
| WO2017023631A1 (en) | 2015-08-06 | 2017-02-09 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| US20180271890A1 (en) * | 2015-10-07 | 2018-09-27 | Sandoz Ag | Solid Pharmaceutical Composition Comprising Amorphous Sofosbuvir |
| WO2017072714A1 (en) | 2015-10-30 | 2017-05-04 | Lupin Limited | Stable ledipasvir premix and process of preparation thereof |
| JOP20170127A1 (ar) * | 2016-06-02 | 2017-12-02 | Gilead Pharmasset Llc | صيغة مشتركة مكونة من ثلاث مركبات مضادة للفيروسات |
| BR112019002729A2 (pt) | 2016-08-12 | 2019-05-14 | Sandoz Ag | composição farmacêutica sólida e processo para preparar uma composição farmacêutica sólida |
| WO2018078536A1 (en) | 2016-10-26 | 2018-05-03 | Lupin Limited | Stable solid dispersion of sofosbuvir and process for preparation thereof |
| CN106727516A (zh) * | 2017-01-10 | 2017-05-31 | 山东省立医院 | 一种治疗丙型肝炎的药物组合物 |
| WO2019134971A1 (en) * | 2018-01-04 | 2019-07-11 | Sandoz Ag | Encapsulated particles comprising a pharmaceutically active ingredient |
| US11378965B2 (en) | 2018-11-15 | 2022-07-05 | Toyota Research Institute, Inc. | Systems and methods for controlling a vehicle based on determined complexity of contextual environment |
| CN113209087B (zh) * | 2020-02-05 | 2023-11-07 | 歌礼药业(浙江)有限公司 | 一种抑制冠状病毒的药物组合物及其用途 |
| CN116887866A (zh) | 2020-12-03 | 2023-10-13 | 巴特尔纪念研究院 | 聚合物纳米颗粒和dna纳米结构组合物及用于非病毒递送的方法 |
| JP2024516108A (ja) | 2021-04-07 | 2024-04-12 | バテル・メモリアル・インスティテュート | 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術 |
| NL2028762B1 (en) * | 2021-07-16 | 2023-01-23 | Seranovo Holding B V | Micelle-generating formulations for enhanced bioavailability |
| KR102842201B1 (ko) * | 2023-09-19 | 2025-08-06 | 한국해양과학기술원 | Lng 추진 선박용 이산화탄소 액화 시스템 및 방법 |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| US12441996B2 (en) | 2023-12-08 | 2025-10-14 | Battelle Memorial Institute | Use of DNA origami nanostructures for molecular information based data storage systems |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100664822B1 (ko) * | 2002-02-01 | 2007-01-04 | 화이자 프로덕츠 인코포레이티드 | 변형된 분무-건조 장치를 이용한 균질한 분무-건조된 고체비결정성 약물 분산액의 제조 방법 |
| AU2005253957B2 (en) * | 2004-06-08 | 2011-08-25 | Janssen Pharmaceutica Nv | Pharmaceutical compositions |
| WO2007109604A2 (en) * | 2006-03-20 | 2007-09-27 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions |
| US7964580B2 (en) * | 2007-03-30 | 2011-06-21 | Pharmasset, Inc. | Nucleoside phosphoramidate prodrugs |
| PE20091041A1 (es) * | 2007-10-19 | 2009-08-22 | Abbott Gmbh & Co Kg | Producto de dispersion solida que contiene un compuesto a base de n-aril urea |
| US20110207660A1 (en) * | 2008-08-07 | 2011-08-25 | Schering Corporation | Pharmaceutical formulations of an hcv protease inhibitor in a solid molecular dispersion |
| MX340792B (es) * | 2009-02-27 | 2016-07-25 | Ortho-Mcneil-Janssen Pharmaceuticals Inc * | Sal amorfa de un inhibidor macrociclico de virus de hepatitis c. |
| RS56654B8 (sr) * | 2009-05-13 | 2021-06-30 | Gilead Pharmasset Llc | Antiviralna jedinjenja |
| US8937150B2 (en) * | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| EA020031B1 (ru) * | 2009-06-11 | 2014-08-29 | Эббви Бахамаз Лтд. | Противовирусные соединения |
| US8415374B2 (en) * | 2009-10-12 | 2013-04-09 | Bristol-Myers Squibb Company | Combinations of hepatitis C virus inhibitors |
| NZ605440A (en) * | 2010-06-10 | 2014-05-30 | Abbvie Bahamas Ltd | Solid compositions comprising an hcv inhibitor |
| TW201446286A (zh) * | 2013-01-31 | 2014-12-16 | Gilead Pharmasset Llc | 抗病毒化合物之固態分散調製劑 |
-
2012
- 2012-12-18 HK HK15101710.0A patent/HK1201186A1/xx unknown
- 2012-12-18 CN CN201280064815.5A patent/CN104010631B/zh active Active
- 2012-12-18 JP JP2014550335A patent/JP5781706B2/ja not_active Expired - Fee Related
- 2012-12-18 CA CA2857339A patent/CA2857339C/en active Active
- 2012-12-18 MX MX2014008008A patent/MX2014008008A/es unknown
- 2012-12-18 WO PCT/US2012/070349 patent/WO2013101550A1/en not_active Ceased
- 2012-12-18 EP EP12809070.1A patent/EP2797586A1/en not_active Withdrawn
- 2012-12-18 DE DE212012000197.2U patent/DE212012000197U1/de not_active Expired - Lifetime
- 2012-12-18 EP EP15156387.1A patent/EP2907505A3/en not_active Withdrawn
- 2012-12-18 US US13/717,993 patent/US20130172239A1/en not_active Abandoned
-
2015
- 2015-07-14 JP JP2015140513A patent/JP2015227352A/ja active Pending
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