JP2015513557A5 - - Google Patents

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Publication number
JP2015513557A5
JP2015513557A5 JP2014561064A JP2014561064A JP2015513557A5 JP 2015513557 A5 JP2015513557 A5 JP 2015513557A5 JP 2014561064 A JP2014561064 A JP 2014561064A JP 2014561064 A JP2014561064 A JP 2014561064A JP 2015513557 A5 JP2015513557 A5 JP 2015513557A5
Authority
JP
Japan
Prior art keywords
agent according
therapeutic agent
pain
peripheral neuropathy
neuropathic pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014561064A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015513557A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/029258 external-priority patent/WO2013134336A2/en
Publication of JP2015513557A publication Critical patent/JP2015513557A/ja
Publication of JP2015513557A5 publication Critical patent/JP2015513557A5/ja
Pending legal-status Critical Current

Links

JP2014561064A 2012-03-09 2013-03-06 疼痛の治療に対するアダプター関連キナーゼ１の阻害 Pending JP2015513557A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261608849P 2012-03-09 2012-03-09
US61/608,849 2012-03-09
PCT/US2013/029258 WO2013134336A2 (en) 2012-03-09 2013-03-06 Inhibition of adaptor associated kinase 1 for the treatment of pain

Publications (2)

Publication Number Publication Date
JP2015513557A JP2015513557A (ja) 2015-05-14
JP2015513557A5 true JP2015513557A5 (enExample) 2016-04-21

Family

ID=47884616

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014561064A Pending JP2015513557A (ja) 2012-03-09 2013-03-06 疼痛の治療に対するアダプター関連キナーゼ１の阻害

Country Status (14)

Country Link
US (4) US20140080834A1 (enExample)
EP (2) EP2822555B1 (enExample)
JP (1) JP2015513557A (enExample)
CN (1) CN104220071A (enExample)
AU (1) AU2013230066A1 (enExample)
CA (1) CA2866145A1 (enExample)
DK (1) DK2822555T3 (enExample)
ES (1) ES2657061T3 (enExample)
HK (1) HK1199814A1 (enExample)
HU (1) HUE036040T2 (enExample)
NO (1) NO2935475T3 (enExample)
PL (1) PL2822555T3 (enExample)
PT (1) PT2822555T (enExample)
WO (1) WO2013134336A2 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8969565B2 (en) 2012-03-09 2015-03-03 Lexicon Pharmaceuticals, Inc. Imidazo[1,2-b]pyridazine-based compounds, compositions comprising them, and methods of their use
CN104302649B (zh) * 2012-03-09 2017-06-23 莱西肯医药有限公司 基于吡唑并[1,5‑a]嘧啶的化合物、包含它们的组合物及其使用方法
US8901305B2 (en) 2012-07-31 2014-12-02 Bristol-Myers Squibb Company Aryl lactam kinase inhibitors
WO2014130258A1 (en) 2013-02-22 2014-08-28 Bristol-Myers Squibb Company 5h-chromeno[3,4-c]pyridines as inhibitors of adaptor associated kinase 1 (aak1)
WO2014175370A1 (ja) * 2013-04-25 2014-10-30 塩野義製薬株式会社 ピロリジン誘導体およびそれらを含有する医薬組成物
TW201506024A (zh) * 2013-07-02 2015-02-16 必治妥美雅史谷比公司 作為有效ｒｏｃｋ抑制劑的三環甲醯胺衍生物
EP3019475A1 (en) 2013-07-08 2016-05-18 Bristol-Myers Squibb Company Aryl amide kinase inhibitors
TW201542550A (zh) * 2013-09-06 2015-11-16 Lexicon Pharmaceuticals Inc 吡唑并［１，５－ａ］嘧啶基化合物、包含彼之組合物以及使用彼之方法
AR097543A1 (es) * 2013-09-06 2016-03-23 Lexicon Pharmaceuticals Inc COMPUESTOS BASADOS EN IMIDAZO[1,2-b]PIRIDAZINA, COMPOSICIONES QUE LOS COMPRENDEN Y SUS MÉTODOS DE USO
CN105683196B (zh) * 2013-09-11 2018-12-21 百时美施贵宝公司 基于芳基醚的激酶抑制剂
JP6473146B2 (ja) * 2013-10-11 2019-02-20 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ ピロロトリアジンキナーゼ阻害剤
EA201691397A1 (ru) * 2014-01-31 2016-11-30 Бристол-Майерс Сквибб Компани Хинолиновые ингибиторы киназы
TW201620911A (zh) * 2014-03-17 2016-06-16 雷西肯製藥股份有限公司 銜接子關聯激酶１之抑制劑、包含其之組成物、及其使用方法
EA028942B1 (ru) * 2014-04-02 2018-01-31 Бристол-Майерс Сквибб Компани Биарильные ингибиторы киназы
EP3177604A1 (en) * 2014-08-05 2017-06-14 Bristol-Myers Squibb Company Heterocyclic kinase inhibitors
HRP20240644T1 (hr) 2014-11-06 2024-08-02 Bial-R&D Investments, S.A. Supstituirani pirazolo(1,5-a)pirimidini i njihova uporaba u liječenju medicinskih poremećaja
US10174044B2 (en) 2015-04-10 2019-01-08 Bristol-Myers Squibb Company Fused pyridines as kinase inhibitors
CN108290843B (zh) 2015-10-01 2021-08-24 百时美施贵宝公司 联芳基激酶抑制剂
ES2765730T3 (es) 2015-10-01 2020-06-10 Bristol Myers Squibb Co Inhibidores de biaril cinasa
JP7046827B2 (ja) 2016-04-06 2022-04-04 リソソーマル・セラピューティクス・インコーポレイテッド イミダゾ［１，５－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用
SG11201808830YA (en) 2016-04-06 2018-11-29 Lysosomal Therapeutics Inc Pyrazolo[1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders
JP7164774B2 (ja) 2016-05-05 2022-11-02 ビアル－アール・アンド・ディ・インベストメンツ・ソシエダーデ・アノニマ 置換イミダゾ［１，２－ｂ］ピリダジン、置換イミダゾ［１，５－ｂ］ピリダジン、関連化合物、および医学的障害の治療におけるその使用
WO2018013430A2 (en) 2016-07-12 2018-01-18 Arisan Therapeutics Inc. Heterocyclic compounds for the treatment of arenavirus infection
US12419865B2 (en) 2018-12-06 2025-09-23 Arisan Therapeutics Inc. Compounds for the treatment of arenavirus infection
KR102590438B1 (ko) * 2020-10-16 2023-10-18 김홍렬 Pmca 억제제를 포함하는 코로나바이러스 감염 또는 감염 질환의 예방 또는 소독용 조성물
KR102590444B1 (ko) * 2020-10-16 2023-10-18 김홍렬 Pmca 억제제를 포함하는 코로나바이러스 감염 또는 감염 질환의 치료용 조성물
WO2023196584A2 (en) * 2022-04-08 2023-10-12 New York University Endocytosis inhibitors and their use for pain treatment
WO2025225608A1 (en) * 2024-04-23 2025-10-30 Otsuka Pharmaceutical Co., Ltd. Tetrahydropyrazolopyridine derivative
WO2025230262A1 (ko) * 2024-04-29 2025-11-06 심플렉스 주식회사 신규한 헤테로아릴 유도체 및 이의 aak1 억제 용도

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US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
WO1993004169A1 (en) 1991-08-20 1993-03-04 Genpharm International, Inc. Gene targeting in animal cells using isogenic dna constructs
WO2007025090A2 (en) * 2005-08-25 2007-03-01 Kalypsys, Inc. Heterobicyclic and - tricyclic inhibitors of mapk/erk kinase
JP2010508315A (ja) * 2006-10-30 2010-03-18 ノバルティス アーゲー 抗炎症剤としてのヘテロ環式化合物
EA019507B1 (ru) * 2008-05-13 2014-04-30 Айрм Ллк Конденсированные азотсодержащие гетероциклы и содержащие их композиции в качестве ингибиторов киназы
WO2010028005A1 (en) * 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules

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