JP2015502167A5 - - Google Patents

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Publication number
JP2015502167A5
JP2015502167A5 JP2014548013A JP2014548013A JP2015502167A5 JP 2015502167 A5 JP2015502167 A5 JP 2015502167A5 JP 2014548013 A JP2014548013 A JP 2014548013A JP 2014548013 A JP2014548013 A JP 2014548013A JP 2015502167 A5 JP2015502167 A5 JP 2015502167A5
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JP
Japan
Prior art keywords
light chain
amino acid
enterokinase light
peptide
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2014548013A
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English (en)
Japanese (ja)
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JP2015502167A (ja
JP6138151B2 (ja
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Publication date
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Priority claimed from PCT/EP2012/076372 external-priority patent/WO2013092855A1/en
Publication of JP2015502167A publication Critical patent/JP2015502167A/ja
Publication of JP2015502167A5 publication Critical patent/JP2015502167A5/ja
Application granted granted Critical
Publication of JP6138151B2 publication Critical patent/JP6138151B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2014548013A 2011-12-23 2012-12-20 修飾されたエンテロキナーゼ軽鎖 Active JP6138151B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2011/002169 2011-12-23
CN2011002169 2011-12-23
PCT/EP2012/076372 WO2013092855A1 (en) 2011-12-23 2012-12-20 Modified enterokinase light chain

Publications (3)

Publication Number Publication Date
JP2015502167A JP2015502167A (ja) 2015-01-22
JP2015502167A5 true JP2015502167A5 (enExample) 2016-02-12
JP6138151B2 JP6138151B2 (ja) 2017-05-31

Family

ID=47561561

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014548013A Active JP6138151B2 (ja) 2011-12-23 2012-12-20 修飾されたエンテロキナーゼ軽鎖

Country Status (5)

Country Link
US (1) US9611466B2 (enExample)
EP (1) EP2794875B1 (enExample)
JP (1) JP6138151B2 (enExample)
ES (1) ES2819288T3 (enExample)
WO (1) WO2013092855A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6200087B2 (ja) * 2013-12-17 2017-09-20 ノヴォ ノルディスク アー/エス エンテロキナーゼ切断性ポリペプチド
WO2017118752A1 (en) * 2016-01-07 2017-07-13 Novo Nordisk A/S Modified enterokinase light chain and its preparation method
CN109136209B (zh) * 2018-07-18 2021-07-06 上海雅心生物技术有限公司 肠激酶轻链突变体及其应用
CN114807101B (zh) * 2022-06-20 2022-09-16 北京惠之衡生物科技有限公司 包含牛肠激酶轻链蛋白的融合蛋白及其表达载体和重组工程菌
CN116064491A (zh) * 2022-06-20 2023-05-05 北京惠之衡生物科技有限公司 牛肠激酶轻链蛋白突变体及其重组融合蛋白

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679189B1 (en) 1993-01-15 2003-06-04 Genetics Institute, LLC Cloning of enterokinase and method of use
KR19990073067A (ko) 1999-03-13 1999-10-05 문정복 레일천공기
KR100507980B1 (ko) 2002-06-18 2005-08-17 프로테온 주식회사 엔테로키나제 경사슬의 아미노말단 또는 카르복실말단이 변형된 재조합 엔테로키나제
CN1214107C (zh) 2002-07-26 2005-08-10 刘建宁 一种具有高活性和高稳定性的肠激酶轻链变体
CN1869236A (zh) 2005-05-24 2006-11-29 上海新生源医药研究有限公司 一种重组牛肠激酶的生产方法
WO2008136014A1 (en) 2007-05-07 2008-11-13 Usv Limited Cloning and expression of enterokinase and its process for production
CN101624587A (zh) 2007-05-11 2010-01-13 上海张江生物技术有限公司 重组牛肠激酶、其制备方法及用途
CN102061302B (zh) 2010-11-26 2012-07-04 扬子江药业集团北京海燕药业有限公司 肠激酶轻链基因的合成及其表达产物的制备方法

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