JP2015501843A - miR−21およびmiR−29a、エキソソーム阻害、およびがん転移に関する方法および組成物 - Google Patents
miR−21およびmiR−29a、エキソソーム阻害、およびがん転移に関する方法および組成物 Download PDFInfo
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- JP2015501843A JP2015501843A JP2014547416A JP2014547416A JP2015501843A JP 2015501843 A JP2015501843 A JP 2015501843A JP 2014547416 A JP2014547416 A JP 2014547416A JP 2014547416 A JP2014547416 A JP 2014547416A JP 2015501843 A JP2015501843 A JP 2015501843A
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/323—Chemical structure of the sugar modified ring structure
- C12N2310/3231—Chemical structure of the sugar modified ring structure having an additional ring, e.g. LNA, ENA
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- C12N2320/00—Applications; Uses
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- C12Q2600/00—Oligonucleotides characterized by their use
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- C12Q2600/00—Oligonucleotides characterized by their use
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161569862P | 2011-12-13 | 2011-12-13 | |
| US61/569,862 | 2011-12-13 | ||
| US201261644980P | 2012-05-09 | 2012-05-09 | |
| US61/644,980 | 2012-05-09 | ||
| PCT/US2012/069484 WO2013090556A1 (en) | 2011-12-13 | 2012-12-13 | Methods and compositions related to mir-21 and mir-29a, exosome inhibition, and cancer metastasis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015501843A true JP2015501843A (ja) | 2015-01-19 |
| JP2015501843A5 JP2015501843A5 (enExample) | 2016-01-21 |
Family
ID=48613170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014547416A Pending JP2015501843A (ja) | 2011-12-13 | 2012-12-13 | miR−21およびmiR−29a、エキソソーム阻害、およびがん転移に関する方法および組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9481885B2 (enExample) |
| EP (1) | EP2790735A4 (enExample) |
| JP (1) | JP2015501843A (enExample) |
| CN (1) | CN104619353A (enExample) |
| AU (1) | AU2012352265B2 (enExample) |
| CA (1) | CA2859430A1 (enExample) |
| WO (1) | WO2013090556A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015138426A1 (en) * | 2014-03-10 | 2015-09-17 | Croce Carlo M | Compositions and methods for treating cachexia |
| CN105316336B (zh) * | 2015-10-20 | 2018-01-12 | 浙江大学 | 一种抑制Bid蛋白表达的miR‑29a模拟物及其应用 |
| CN107206104A (zh) * | 2015-11-13 | 2017-09-26 | 擎新(厦门)生物科技有限公司 | 基于微小RNA miR‑574‑5p的化合物作为免疫调节剂的用途及它们的组合物 |
| US11243215B2 (en) | 2016-01-14 | 2022-02-08 | The Regents Of The University Of California | 3D-exoquant method for the analysis of surface molecules and quantification of tissue-specific exosomes in biological fluids |
| WO2017139553A1 (en) * | 2016-02-10 | 2017-08-17 | Ymir Genomics Llc | Bioparticle isolation and therapeutic application thereof |
| EP3417877A4 (en) * | 2016-02-18 | 2019-10-02 | Kyoto University | FOR INHIBITING THE GENETIC FUNCTION IN EXOSOM COMPLEX AND CANCER REPRODUCTION AND / OR METASTASE UPPRESSOR |
| US20180235936A1 (en) * | 2017-02-17 | 2018-08-23 | University Of Notre Dame Du Lac | Cancer treatment methods |
| WO2018160699A1 (en) * | 2017-03-01 | 2018-09-07 | University Of Notre Dame Du Lac | Biomarkers for diagnosis, prediction and/or prognosis of pancreatic cancer and uses thereof |
| CN107412250B (zh) * | 2017-05-11 | 2019-03-05 | 南京北恒生物科技有限公司 | miR-193a-3p的应用 |
| CN115856300B (zh) * | 2022-08-01 | 2024-06-21 | 南京大学 | 一种与肺癌相关的血浆外泌体蛋白标志物、抗体及其应用 |
| CN116650513A (zh) * | 2023-07-25 | 2023-08-29 | 中国农业大学 | miR-29在制备调节细胞能量代谢和细胞干性的制剂中的应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009521952A (ja) * | 2006-01-05 | 2009-06-11 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | 膵内分泌腫瘍及び膵腺房腫瘍におけるマイクロrna発現異常 |
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| US8664192B2 (en) | 2011-03-07 | 2014-03-04 | The Ohio State University | Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer |
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2012
- 2012-12-13 CN CN201280067430.4A patent/CN104619353A/zh active Pending
- 2012-12-13 US US14/364,159 patent/US9481885B2/en not_active Expired - Fee Related
- 2012-12-13 WO PCT/US2012/069484 patent/WO2013090556A1/en not_active Ceased
- 2012-12-13 JP JP2014547416A patent/JP2015501843A/ja active Pending
- 2012-12-13 AU AU2012352265A patent/AU2012352265B2/en not_active Ceased
- 2012-12-13 EP EP12857918.2A patent/EP2790735A4/en not_active Withdrawn
- 2012-12-13 CA CA2859430A patent/CA2859430A1/en not_active Abandoned
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2016
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| JP2009521952A (ja) * | 2006-01-05 | 2009-06-11 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | 膵内分泌腫瘍及び膵腺房腫瘍におけるマイクロrna発現異常 |
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|---|---|
| US20170002353A1 (en) | 2017-01-05 |
| WO2013090556A1 (en) | 2013-06-20 |
| EP2790735A4 (en) | 2015-12-09 |
| US9481885B2 (en) | 2016-11-01 |
| CN104619353A (zh) | 2015-05-13 |
| AU2012352265B2 (en) | 2017-02-16 |
| EP2790735A1 (en) | 2014-10-22 |
| US20140323553A1 (en) | 2014-10-30 |
| CA2859430A1 (en) | 2013-06-20 |
| AU2012352265A1 (en) | 2014-06-26 |
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