JP2015198665A5 - - Google Patents

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Publication number
JP2015198665A5
JP2015198665A5 JP2015117465A JP2015117465A JP2015198665A5 JP 2015198665 A5 JP2015198665 A5 JP 2015198665A5 JP 2015117465 A JP2015117465 A JP 2015117465A JP 2015117465 A JP2015117465 A JP 2015117465A JP 2015198665 A5 JP2015198665 A5 JP 2015198665A5
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JP
Japan
Prior art keywords
enzyme
cell
seq
nicotinamide
nicotinamidase
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JP2015117465A
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English (en)
Japanese (ja)
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JP6602561B2 (ja
JP2015198665A (ja
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Publication of JP2015198665A publication Critical patent/JP2015198665A/ja
Publication of JP2015198665A5 publication Critical patent/JP2015198665A5/ja
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Publication of JP6602561B2 publication Critical patent/JP6602561B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2015117465A 2002-08-09 2015-06-10 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物 Expired - Fee Related JP6602561B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US40225402P 2002-08-09 2002-08-09
US60/402,254 2002-08-09
US42861402P 2002-11-22 2002-11-22
US60/428,614 2002-11-22

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2010162637A Division JP2011015682A (ja) 2002-08-09 2010-07-20 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物

Publications (3)

Publication Number Publication Date
JP2015198665A JP2015198665A (ja) 2015-11-12
JP2015198665A5 true JP2015198665A5 (enExample) 2016-05-26
JP6602561B2 JP6602561B2 (ja) 2019-11-06

Family

ID=31720582

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2004529297A Pending JP2005535342A (ja) 2002-08-09 2003-08-08 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物
JP2010162637A Pending JP2011015682A (ja) 2002-08-09 2010-07-20 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物
JP2015117465A Expired - Fee Related JP6602561B2 (ja) 2002-08-09 2015-06-10 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2004529297A Pending JP2005535342A (ja) 2002-08-09 2003-08-08 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物
JP2010162637A Pending JP2011015682A (ja) 2002-08-09 2010-07-20 細胞及び生物の寿命を延ばし、ストレス耐性を増す方法及び組成物

Country Status (5)

Country Link
EP (2) EP2431480A3 (enExample)
JP (3) JP2005535342A (enExample)
AU (2) AU2003264037B2 (enExample)
CA (2) CA2421269A1 (enExample)
WO (1) WO2004016726A2 (enExample)

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US20050096256A1 (en) 2003-07-01 2005-05-05 President And Fellows Of Harvard College Compositions for manipulating the lifespan and stress response of cells and organisms
US20060025337A1 (en) 2003-07-01 2006-02-02 President And Fellows Of Harvard College Sirtuin related therapeutics and diagnostics for neurodegenerative diseases
AU2004324323A1 (en) * 2003-10-31 2006-06-15 Robarts Research Institute Methods and formulations for protecting cells, and for treating diseases and conditions by optimising the intracellular concentration of NAD
CN101247793B (zh) 2003-12-29 2013-04-10 哈佛大学校长及研究员协会 治疗或预防肥胖和胰岛素抗性病症的组合物
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
CN1964627B (zh) * 2004-06-04 2011-10-19 华盛顿大学 治疗神经病变的方法和组合物
EP1794306B1 (en) 2004-09-24 2009-12-16 Bayer BioScience N.V. Stress resistant plants
US20090012130A1 (en) * 2005-01-25 2009-01-08 The Johns Hopkins University Strategies for Designing Drugs that Target the Sir2 Family of Enzymes
EP1877054A2 (en) 2005-03-30 2008-01-16 Sirtris Pharmaceuticals, Inc. Nicotinamide riboside and analogues thereof
WO2006138418A2 (en) 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
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CA2646476A1 (en) * 2006-03-21 2007-09-27 Bayer Bioscience N.V. Stress resistant plants
RU2415573C2 (ru) 2006-12-11 2011-04-10 Джапэн Сайенс Энд Текнолоджи Эйдженси Регулятор роста растений и его применение
WO2009063806A1 (ja) * 2007-11-13 2009-05-22 Japan Science And Technology Agency 糖度が向上した植物体を作出するための組成物及びその利用
JP5570731B2 (ja) * 2008-02-28 2014-08-13 旭化成ファーマ株式会社 ピロリン酸の測定方法
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JP2011115098A (ja) * 2009-12-04 2011-06-16 Nippon Menaade Keshohin Kk 加齢による皮膚明度の低下を予測する皮膚評価方法
CN103987249B (zh) 2011-12-12 2015-10-21 冈山县 用于提高植物的氨基酸含量的化合物及其应用
WO2014059034A2 (en) 2012-10-09 2014-04-17 President And Fellows Of Harvard College Nad biosynthesis and precursors for the treatment and prevention of cancer and proliferation
US20160287621A1 (en) * 2013-11-06 2016-10-06 President And Fellows Of Harvard College Biological production of nad precursors and analogs
CN106536535A (zh) 2014-06-02 2017-03-22 葛兰素史密斯克莱知识产权（第2 号）有限公司 结晶的β‑D‑烟酰胺核苷的制备和用途
WO2015186114A1 (en) 2014-06-06 2015-12-10 Glaxosmithkline Intellectual Property (No.2) Limited Nicotinamide riboside analogs and pharmaceutical compositions and uses thereof
JP6623015B2 (ja) * 2014-09-29 2019-12-18 国立研究開発法人理化学研究所 植物の耐塩性向上剤
WO2020097116A1 (en) * 2018-11-05 2020-05-14 Rejuvenation Therapeutics Compositions and methods for culturing yeast cells
JP7702934B2 (ja) * 2019-08-14 2025-07-04 メトロ インターナショナル バイオテック，エルエルシー ニコチンアミドアデニンジヌクレオチドの差次的モジュレーションのための化合物及び組成物
CN111394268B (zh) * 2019-12-20 2021-06-18 合肥康诺生物制药有限公司 基因工程菌及其构建方法、应用，生产nad+的方法
CN112451673A (zh) * 2020-12-10 2021-03-09 汤臣倍健股份有限公司 线粒体功能干预材料在制备改善线粒体功能的保健品或药品中的应用及其筛选方法

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US7977049B2 (en) * 2002-08-09 2011-07-12 President And Fellows Of Harvard College Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
EP1794306B1 (en) * 2004-09-24 2009-12-16 Bayer BioScience N.V. Stress resistant plants
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US9609948B2 (en) 2015-04-28 2017-04-04 Qianglong Furniture Co., Ltd. Rotating armrest apparatus

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