JP2015120736A5 - - Google Patents
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- JP2015120736A5 JP2015120736A5 JP2015028510A JP2015028510A JP2015120736A5 JP 2015120736 A5 JP2015120736 A5 JP 2015120736A5 JP 2015028510 A JP2015028510 A JP 2015028510A JP 2015028510 A JP2015028510 A JP 2015028510A JP 2015120736 A5 JP2015120736 A5 JP 2015120736A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- pharmaceutically acceptable
- composition according
- methylsulfanyl
- triol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 208000030159 metabolic disease Diseases 0.000 claims 3
- QKDRXGFQVGOQKS-CRSSMBPESA-N (2s,3r,4r,5s,6r)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-methylsulfanyloxane-3,4,5-triol Chemical compound C1=CC(OCC)=CC=C1CC1=CC([C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](SC)O2)O)=CC=C1Cl QKDRXGFQVGOQKS-CRSSMBPESA-N 0.000 claims 2
- 208000016097 disease of metabolism Diseases 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84815606P | 2006-09-29 | 2006-09-29 | |
| US60/848,156 | 2006-09-29 | ||
| US90571407P | 2007-03-08 | 2007-03-08 | |
| US60/905,714 | 2007-03-08 | ||
| US94878007P | 2007-07-10 | 2007-07-10 | |
| US60/948,780 | 2007-07-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012254023A Division JP5701845B2 (ja) | 2006-09-29 | 2012-11-20 | ナトリウム／グルコース共輸送体２の阻害剤としてのフロリジンアナログ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015120736A JP2015120736A (ja) | 2015-07-02 |
| JP2015120736A5 true JP2015120736A5 (enExample) | 2015-11-26 |
| JP5889453B2 JP5889453B2 (ja) | 2016-03-22 |
Family
ID=38947681
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009530593A Active JP5283625B2 (ja) | 2006-09-29 | 2007-09-27 | ナトリウム／グルコース共輸送体２の阻害剤としてのフロリジンアナログ |
| JP2012254023A Active JP5701845B2 (ja) | 2006-09-29 | 2012-11-20 | ナトリウム／グルコース共輸送体２の阻害剤としてのフロリジンアナログ |
| JP2015028510A Active JP5889453B2 (ja) | 2006-09-29 | 2015-02-17 | ナトリウム／グルコース共輸送体２の阻害剤としてのフロリジンアナログ |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009530593A Active JP5283625B2 (ja) | 2006-09-29 | 2007-09-27 | ナトリウム／グルコース共輸送体２の阻害剤としてのフロリジンアナログ |
| JP2012254023A Active JP5701845B2 (ja) | 2006-09-29 | 2012-11-20 | ナトリウム／グルコース共輸送体２の阻害剤としてのフロリジンアナログ |
Country Status (24)
| Country | Link |
|---|---|
| US (5) | US7781577B2 (enExample) |
| EP (2) | EP2308841B1 (enExample) |
| JP (3) | JP5283625B2 (enExample) |
| KR (2) | KR101492277B1 (enExample) |
| AR (1) | AR063047A1 (enExample) |
| AT (1) | ATE496888T1 (enExample) |
| AU (1) | AU2007304971B2 (enExample) |
| BR (1) | BRPI0717156B8 (enExample) |
| CA (1) | CA2664688C (enExample) |
| DE (1) | DE602007012292D1 (enExample) |
| DK (2) | DK2308841T3 (enExample) |
| EA (1) | EA016511B1 (enExample) |
| ES (1) | ES2477216T3 (enExample) |
| FR (1) | FR19C1053I2 (enExample) |
| HU (1) | HUS1900038I1 (enExample) |
| IL (1) | IL197836A (enExample) |
| MX (1) | MX2009003305A (enExample) |
| NL (1) | NL301003I2 (enExample) |
| NO (1) | NO345139B1 (enExample) |
| NZ (1) | NZ575811A (enExample) |
| PL (2) | PL2089361T4 (enExample) |
| PT (2) | PT2089361E (enExample) |
| TW (1) | TWI499414B (enExample) |
| WO (1) | WO2008042688A2 (enExample) |
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| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| WO2010009243A1 (en) | 2008-07-15 | 2010-01-21 | Theracos, Inc. | Deuterated benzylbenzene derivatives and methods of use |
| TWI472521B (zh) * | 2008-07-17 | 2015-02-11 | Lexicon Pharmaceuticals Inc | （２ｓ，３ｒ，４ｒ，５ｓ，６ｒ）－２－（４－氯－３－（４－乙氧苄基）苯基）－６－（甲硫）四氫－２ｈ－哌喃－３，４，５－三醇的固體形態與其使用方法 |
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| WO2011070592A2 (en) | 2009-12-09 | 2011-06-16 | Panacea Biotec Ltd. | Novel sugar derivatives |
| TWI562775B (en) * | 2010-03-02 | 2016-12-21 | Lexicon Pharmaceuticals Inc | Methods of using inhibitors of sodium-glucose cotransporters 1 and 2 |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8933024B2 (en) | 2010-06-18 | 2015-01-13 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| WO2012025857A1 (en) * | 2010-08-23 | 2012-03-01 | Hetero Research Foundation | Cycloalkyl methoxybenzyl phenyl pyran derivatives as sodium dependent glucose co transporter (sglt2) inhibitors |
| CN102453026A (zh) | 2010-10-27 | 2012-05-16 | 上海艾力斯医药科技有限公司 | C-芳基葡糖苷衍生物、制备方法及其应用 |
| IL295438B2 (en) | 2011-01-05 | 2026-05-01 | Lexicon Pharmaceuticals Inc | Compositions containing and methods for using inhibitors of sodium-glucose cotransporters 1 and 2 |
| JP5876570B2 (ja) * | 2011-06-01 | 2016-03-02 | グリーン・クロス・コーポレイションＧｒｅｅｎ Ｃｒｏｓｓ Ｃｏｒｐ． | Ｓｇｌｔ２阻害剤としての新規のジフェニルメタン誘導体 |
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| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2755722B1 (en) | 2011-09-13 | 2017-05-24 | Panacea Biotec Ltd. | Novel sglt inhibitors |
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| HUE068152T2 (hu) | 2014-09-25 | 2024-12-28 | Boehringer Ingelheim Vetmedica Gmbh | SGLT2-gátlók és dopamin agonisták kombinációs kezelése anyagcserezavarok megelõzésére lófélékben |
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| EA201990951A1 (ru) | 2016-10-19 | 2019-11-29 | Комбинации, содержащие ssao/vap-1 ингибитор и sglt2-ингибитор, и их применение | |
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| CN111989103A (zh) | 2018-04-17 | 2020-11-24 | 勃林格殷格翰国际有限公司 | 药物组合物、其治疗方法和用途 |
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| WO2020039394A1 (en) | 2018-08-24 | 2020-02-27 | Novartis Ag | New drug combinations |
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| SG11202102440SA (en) | 2018-10-29 | 2021-04-29 | Boehringer Ingelheim Int | Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof |
| JP7482146B2 (ja) * | 2019-03-01 | 2024-05-13 | レクシコン ファーマシューティカルズ インコーポレイテッド | １型真性糖尿病を有する患者の治療のためのソタグリフロジンの使用 |
| US20220324897A1 (en) * | 2019-07-05 | 2022-10-13 | Shandong Danhong Pharmaceutical Co., Ltd. | Crystal form of sglt inhibitor and application thereof |
| CA3145678C (en) * | 2019-07-26 | 2022-08-23 | Medshine Discovery Inc. | Sglt2/dpp4 inhibitor and application thereof |
| MX2022001029A (es) * | 2019-07-26 | 2022-05-24 | Dongbao Purple Star Hangzhou Biopharmaceutical Co Ltd | Inhibidor de sglts/dpp4 y aplicación del mismo. |
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