JP2014534202A5 - - Google Patents
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- JP2014534202A5 JP2014534202A5 JP2014536116A JP2014536116A JP2014534202A5 JP 2014534202 A5 JP2014534202 A5 JP 2014534202A5 JP 2014536116 A JP2014536116 A JP 2014536116A JP 2014536116 A JP2014536116 A JP 2014536116A JP 2014534202 A5 JP2014534202 A5 JP 2014534202A5
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- JP
- Japan
- Prior art keywords
- vaccine composition
- peptide fragment
- amino acid
- acid residues
- composition according
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201170574 | 2011-10-17 | ||
| DKPA201170574 | 2011-10-17 | ||
| PCT/DK2012/050386 WO2013056716A1 (en) | 2011-10-17 | 2012-10-17 | Pd-l1 based immunotherapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014534202A JP2014534202A (ja) | 2014-12-18 |
| JP2014534202A5 true JP2014534202A5 (enExample) | 2015-12-03 |
| JP6259763B2 JP6259763B2 (ja) | 2018-01-10 |
Family
ID=47115103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014536116A Active JP6259763B2 (ja) | 2011-10-17 | 2012-10-17 | Ｐｄ−ｌ１に基づく免疫療法 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9669078B2 (enExample) |
| EP (2) | EP2768524B1 (enExample) |
| JP (1) | JP6259763B2 (enExample) |
| CN (2) | CN113444165A (enExample) |
| BR (1) | BR112014009526B8 (enExample) |
| CA (1) | CA2850245C (enExample) |
| CY (1) | CY1125453T1 (enExample) |
| DK (1) | DK2768524T3 (enExample) |
| ES (1) | ES2918580T3 (enExample) |
| HR (1) | HRP20220924T1 (enExample) |
| HU (1) | HUE059406T2 (enExample) |
| LT (1) | LT2768524T (enExample) |
| PL (1) | PL2768524T3 (enExample) |
| PT (1) | PT2768524T (enExample) |
| SI (1) | SI2768524T1 (enExample) |
| WO (1) | WO2013056716A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2850245C (en) * | 2011-10-17 | 2020-04-28 | Herlev Hospital | Pd-l1 based immunotherapy |
| TWI676636B (zh) * | 2013-07-12 | 2019-11-11 | Ｖｌｐ醫療股份有限公司 | 包含ｐｄ－１抗原或ｐｄ－１配體抗原的類病毒粒子 |
| US10816554B2 (en) * | 2014-04-04 | 2020-10-27 | The Board Of Trustees Of The Leland Stanford Junior University | Ligand discovery for T cell receptors |
| WO2016015095A1 (en) * | 2014-07-31 | 2016-02-04 | The University Of Western Australia | A method for the identification of immunotherapy-drug combinations using a network approach |
| SI3193917T1 (sl) | 2014-09-17 | 2022-02-28 | Io Biotech Aps | Sestavki cepiva, ki vsebujejo triptofan 2,3-dioksigenazo ali njene delce |
| JP6918333B2 (ja) * | 2014-09-17 | 2021-08-11 | 学校法人近畿大学 | 細胞性免疫に認識されるペプチド、及びそれを利用した医薬薬剤 |
| WO2016057898A1 (en) | 2014-10-10 | 2016-04-14 | Idera Pharmaceuticals, Inc. | Treatment of cancer using tlr9 agonist with checkpoint inhibitors |
| WO2016077709A1 (en) * | 2014-11-14 | 2016-05-19 | Liquid Genomics, Inc. | Use of circulating cell-free rna for diagnosis and/or monitoring cancer |
| EP3294329B1 (en) * | 2015-05-15 | 2020-04-15 | Reber Genetics Co., Ltd. | Novel baculovirus vectors and methods of use |
| CN108368507B (zh) | 2015-09-02 | 2022-03-22 | 阿尔尼拉姆医药品有限公司 | 程序性细胞死亡1配体1(PD-L1)的iRNA组合物及其使用方法 |
| IL257940B (en) | 2015-09-16 | 2022-08-01 | Herlev Hospital | Vaccines that include the CC motif. Chemokine 22 or fragments thereof |
| EP4316517A3 (en) * | 2016-03-04 | 2024-05-29 | IO Biotech ApS | Combination therapy against cancer |
| TWI794662B (zh) * | 2016-03-14 | 2023-03-01 | 瑞士商赫孚孟拉羅股份公司 | 用於降低pd-l1表現之寡核苷酸 |
| BR112018068461A2 (pt) | 2016-03-15 | 2019-01-22 | Mersana Therapeutics Inc | conjugado, composição farmacêutica, métodos para preparação de um conjugado e para alívio de um sintoma de um câncer. |
| EP3468585A2 (en) | 2016-06-10 | 2019-04-17 | IO Biotech APS | Calr and jak2 vaccine compositions |
| CN109641936B (zh) * | 2016-06-21 | 2023-11-28 | Io生物技术公司 | 用于癌症疫苗中的pdl1肽 |
| CN109983121A (zh) | 2016-06-30 | 2019-07-05 | 昂克诺斯公司 | 治疗性多肽的假型化溶瘤病毒递送 |
| US11135307B2 (en) | 2016-11-23 | 2021-10-05 | Mersana Therapeutics, Inc. | Peptide-containing linkers for antibody-drug conjugates |
| US20190381157A1 (en) * | 2017-01-29 | 2019-12-19 | Zequn Tang | Methods of immune modulation against foreign and/or auto antigens |
| CN108503691B (zh) * | 2017-02-25 | 2021-07-23 | 复旦大学 | 一种人pd-l1蛋白高亲和性肽及其应用 |
| WO2018160538A1 (en) | 2017-02-28 | 2018-09-07 | Mersana Therapeutics, Inc. | Combination therapies of her2-targeted antibody-drug conjugates |
| CA3056807A1 (en) * | 2017-03-17 | 2018-09-20 | Vaximm Ag | Novel pd-l1 targeting dna vaccine for cancer immunotherapy |
| CN111372656A (zh) * | 2017-11-24 | 2020-07-03 | Io生物技术公司 | 抗体依赖性细胞介导的细胞毒性(adcc)的增强 |
| EP3717021A1 (en) | 2017-11-27 | 2020-10-07 | Mersana Therapeutics, Inc. | Pyrrolobenzodiazepine antibody conjugates |
| JP2021506883A (ja) | 2017-12-21 | 2021-02-22 | メルサナ セラピューティクス インコーポレイテッド | ピロロベンゾジアゼピン抗体結合体 |
| EP3731850A4 (en) | 2017-12-29 | 2021-12-01 | Oncorus, Inc. | ONCOLYTIC VIRUS DELIVERY OF THERAPEUTIC POLYPEPTIDES |
| FR3086534B1 (fr) * | 2018-10-01 | 2020-11-06 | Univ Bordeaux | Methode pour traiter une infection par le virus de l'immunodeficience humaine |
| MX2021004906A (es) | 2018-10-29 | 2021-09-10 | Mersana Therapeutics Inc | Conjugados de anticuerpo modificado con cisteína-fármaco con enlazadores que contienen péptidos. |
| CN109593135B (zh) * | 2018-12-29 | 2021-01-15 | 百奥赛图江苏基因生物技术有限公司 | 抗人pd-l1单克隆抗体及其应用 |
| WO2020181402A1 (zh) * | 2019-03-10 | 2020-09-17 | 胡西木 | 一种抗肿瘤多肽及其应用 |
| CN110268071A (zh) * | 2019-04-26 | 2019-09-20 | 嘉兴允英医学检验有限公司 | 一种pd-l1表达水平检测的方法和试剂盒 |
| BR112022005044A2 (pt) * | 2019-09-17 | 2022-07-05 | Ohio State Innovation Foundation | Peptídeo quimérico, peptídeo sintético, composição farmacêutica, anticorpo, método de tratamento |
| US20230227533A1 (en) * | 2020-04-18 | 2023-07-20 | Beijing Zeqin Biomedical Co., Ltd | Fusion peptide for treating autoimmune disease |
| CU24705B1 (es) * | 2020-10-22 | 2024-06-11 | Ct Ingenieria Genetica Biotecnologia | Antígeno quimérico que comprende el dominio extracelular de pd-l1 |
| GB202103673D0 (en) | 2021-03-17 | 2021-04-28 | Io Biotech Aps | Combination therapy for cancer |
| WO2022245841A1 (en) * | 2021-05-17 | 2022-11-24 | Wisconsin Alumni Research Foundation | Synthetic protein for inducing immune tolerance |
| KR102421307B1 (ko) * | 2021-11-19 | 2022-07-14 | 을지대학교 산학협력단 | 암 발생 및 성장 억제를 위한 신규 항암 백신 조성물 및 그를 이용한 백신화 방법 |
| WO2023161350A1 (en) | 2022-02-24 | 2023-08-31 | Io Biotech Aps | Nucleotide delivery of cancer therapy |
| CN114702569B (zh) * | 2022-05-25 | 2023-01-10 | 深圳吉诺因生物科技有限公司 | Pd-l1相关疫苗及其应用 |
| WO2025043075A1 (en) * | 2023-08-24 | 2025-02-27 | The Johns Hopkins University | Methods of treating myocardial infarction, ischemia, and ischemia reperfusion injury |
| EP4527849A1 (en) | 2023-09-19 | 2025-03-26 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz | Hla-independent antigen binders, such as t-cell receptors, against pd-l1 |
| WO2026008026A1 (en) * | 2024-07-03 | 2026-01-08 | Everest Medicines (China) Co., Ltd. | Pd-l1 cancer vaccines and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US58767A (en) | 1866-10-16 | John brougjbton | ||
| US5554372A (en) | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
| US6096313A (en) | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
| CA2389722A1 (en) * | 1999-11-09 | 2001-05-17 | Human Genome Sciences, Inc. | 15 human secreted proteins |
| WO2002079499A1 (en) * | 2001-04-02 | 2002-10-10 | Wyeth | Pd-1, a receptor for b7-4, and uses therefor |
| US7794710B2 (en) | 2001-04-20 | 2010-09-14 | Mayo Foundation For Medical Education And Research | Methods of enhancing T cell responsiveness |
| PT1537878E (pt) * | 2002-07-03 | 2010-11-18 | Ono Pharmaceutical Co | Composições de imunopotenciação |
| WO2004056875A1 (en) * | 2002-12-23 | 2004-07-08 | Wyeth | Antibodies against pd-1 and uses therefor |
| US20090304711A1 (en) * | 2006-09-20 | 2009-12-10 | Drew Pardoll | Combinatorial Therapy of Cancer and Infectious Diseases with Anti-B7-H1 Antibodies |
| US20120269806A1 (en) * | 2007-08-21 | 2012-10-25 | The General Hospital Corporation | Methods of inducing tolerance |
| JP2012500652A (ja) * | 2008-08-25 | 2012-01-12 | アンプリミューン、インコーポレーテッド | 標的化共刺激ポリペプチドおよび癌を処置するための使用方法 |
| US20130017199A1 (en) | 2009-11-24 | 2013-01-17 | AMPLIMMUNE ,Inc. a corporation | Simultaneous inhibition of pd-l1/pd-l2 |
| PT2542590T (pt) * | 2010-03-05 | 2017-08-31 | Univ Johns Hopkins | Composições e métodos para anticorpos e proteínas de fusão imunomoduladores direcionados |
| CA2850245C (en) * | 2011-10-17 | 2020-04-28 | Herlev Hospital | Pd-l1 based immunotherapy |
-
2012
- 2012-10-17 CA CA2850245A patent/CA2850245C/en active Active
- 2012-10-17 LT LTEPPCT/DK2012/050386T patent/LT2768524T/lt unknown
- 2012-10-17 US US14/352,407 patent/US9669078B2/en active Active
- 2012-10-17 CN CN202110437930.3A patent/CN113444165A/zh active Pending
- 2012-10-17 HR HRP20220924TT patent/HRP20220924T1/hr unknown
- 2012-10-17 PL PL12780408.6T patent/PL2768524T3/pl unknown
- 2012-10-17 JP JP2014536116A patent/JP6259763B2/ja active Active
- 2012-10-17 HU HUE12780408A patent/HUE059406T2/hu unknown
- 2012-10-17 PT PT127804086T patent/PT2768524T/pt unknown
- 2012-10-17 BR BR112014009526A patent/BR112014009526B8/pt active IP Right Grant
- 2012-10-17 EP EP12780408.6A patent/EP2768524B1/en active Active
- 2012-10-17 WO PCT/DK2012/050386 patent/WO2013056716A1/en not_active Ceased
- 2012-10-17 DK DK12780408.6T patent/DK2768524T3/da active
- 2012-10-17 ES ES12780408T patent/ES2918580T3/es active Active
- 2012-10-17 CN CN201280050948.7A patent/CN103917243B/zh active Active
- 2012-10-17 SI SI201232003T patent/SI2768524T1/sl unknown
- 2012-10-17 EP EP22163851.3A patent/EP4079319A1/en active Pending
-
2022
- 2022-08-02 CY CY20221100528T patent/CY1125453T1/el unknown
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