JP2013545448A5 - - Google Patents
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- Publication number
- JP2013545448A5 JP2013545448A5 JP2013535100A JP2013535100A JP2013545448A5 JP 2013545448 A5 JP2013545448 A5 JP 2013545448A5 JP 2013535100 A JP2013535100 A JP 2013535100A JP 2013535100 A JP2013535100 A JP 2013535100A JP 2013545448 A5 JP2013545448 A5 JP 2013545448A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide antigen
- antigen
- polypeptide
- composition
- chlamydia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims description 792
- 102000036639 antigens Human genes 0.000 claims description 792
- 108091007433 antigens Proteins 0.000 claims description 792
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 652
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 651
- 229920001184 polypeptide Polymers 0.000 claims description 650
- 241000606161 Chlamydia Species 0.000 claims description 113
- 239000000203 mixture Substances 0.000 claims description 103
- 239000002671 adjuvant Substances 0.000 claims description 27
- 150000001413 amino acids Chemical class 0.000 claims description 21
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 8
- 230000002163 immunogen Effects 0.000 claims description 8
- 210000001744 T-lymphocyte Anatomy 0.000 claims description 6
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 6
- 230000021633 leukocyte mediated immunity Effects 0.000 claims description 6
- 239000011707 mineral Substances 0.000 claims description 6
- 241000606153 Chlamydia trachomatis Species 0.000 claims description 5
- 229940038705 chlamydia trachomatis Drugs 0.000 claims description 5
- 230000028993 immune response Effects 0.000 claims description 5
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 4
- 108091034117 Oligonucleotide Proteins 0.000 claims description 3
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 3
- 230000005875 antibody response Effects 0.000 claims description 3
- 239000000839 emulsion Substances 0.000 claims description 3
- 230000002519 immonomodulatory effect Effects 0.000 claims description 3
- 239000001397 quillaja saponaria molina bark Substances 0.000 claims description 3
- 229930182490 saponin Natural products 0.000 claims description 3
- 150000007949 saponins Chemical class 0.000 claims description 3
- 230000004936 stimulating effect Effects 0.000 claims description 3
- 229960005486 vaccine Drugs 0.000 claims description 2
- 241000124008 Mammalia Species 0.000 description 9
- 108020004707 nucleic acids Proteins 0.000 description 7
- 102000039446 nucleic acids Human genes 0.000 description 7
- 150000007523 nucleic acids Chemical class 0.000 description 7
- 239000002773 nucleotide Substances 0.000 description 4
- 125000003729 nucleotide group Chemical group 0.000 description 4
- 230000005867 T cell response Effects 0.000 description 3
- 230000001939 inductive effect Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40516210P | 2010-10-20 | 2010-10-20 | |
| US61/405,162 | 2010-10-20 | ||
| PCT/US2011/057143 WO2012054755A1 (en) | 2010-10-20 | 2011-10-20 | Chlamydia antigens and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016032672A Division JP2016106117A (ja) | 2010-10-20 | 2016-02-24 | クラミジア抗原及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013545448A JP2013545448A (ja) | 2013-12-26 |
| JP2013545448A5 true JP2013545448A5 (enExample) | 2014-12-04 |
Family
ID=45975625
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013535100A Pending JP2013545448A (ja) | 2010-10-20 | 2011-10-20 | クラミジア抗原及びその使用 |
| JP2016032672A Pending JP2016106117A (ja) | 2010-10-20 | 2016-02-24 | クラミジア抗原及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016032672A Pending JP2016106117A (ja) | 2010-10-20 | 2016-02-24 | クラミジア抗原及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20120135025A1 (enExample) |
| EP (1) | EP2629793A4 (enExample) |
| JP (2) | JP2013545448A (enExample) |
| AU (2) | AU2011316924A1 (enExample) |
| CA (1) | CA2849391A1 (enExample) |
| WO (1) | WO2012054755A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106924728B (zh) | 2009-05-22 | 2021-02-05 | 健诺西生物科学公司 | 针对ⅱ型单纯疱疹病毒的疫苗：诱发免疫应答的组合物和方法 |
| WO2011112906A2 (en) | 2010-03-12 | 2011-09-15 | Children's Medical Center Corporation | Novel immunogens and methods for discovery and screening thereof |
| WO2012074881A2 (en) | 2010-11-24 | 2012-06-07 | Genocea Biosciences, Inc. | Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response |
| JP6199878B2 (ja) * | 2011-11-23 | 2017-09-20 | ジェノセア バイオサイエンシーズ， インコーポレイテッド | 単純ヘルペスウイルス２型に対する核酸ワクチン：免疫応答を誘発する組成物及び方法 |
| WO2014124228A1 (en) | 2013-02-07 | 2014-08-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
| WO2018064232A1 (en) | 2016-09-28 | 2018-04-05 | Genocea Biosciences, Inc. | Methods and compositions for treating herpes |
| WO2018070067A1 (ja) | 2016-10-14 | 2018-04-19 | パナソニックＩｐマネジメント株式会社 | プロジェクションシステム、プロジェクション方法、飛行体システム及び飛行体 |
| JP2021535921A (ja) | 2018-09-12 | 2021-12-23 | アフィニバックス、インコーポレイテッド | 多価肺炎球菌ワクチン |
| WO2023039223A1 (en) | 2021-09-09 | 2023-03-16 | Affinivax, Inc. | Multivalent pneumococcal vaccines |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7041490B1 (en) * | 1997-11-28 | 2006-05-09 | Serono Genetics Institute, S.A. | Chlamydia trachomatis polynucleotides and vectors, recombinant host cells, DNA chips or kits containing the same |
| EP1133572A4 (en) * | 1998-11-12 | 2005-06-15 | Univ California | GENOMIC SEQUENCE OF CHLAMYDIA PNEUMONIAE |
| US20020061848A1 (en) * | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| ES2312649T3 (es) * | 2001-12-12 | 2009-03-01 | Novartis Vaccines And Diagnostics S.R.L. | Inmunizacion frente a chlamydia trachomatis. |
| WO2004074318A2 (en) * | 2003-02-24 | 2004-09-02 | Institut Pasteur | Secreted chlamydia polypeptides, polynucleotides coding therefor, therapeutic and diagnostic uses thereof. |
| JP4896715B2 (ja) * | 2003-06-26 | 2012-03-14 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | Ｃｈｌａｍｙｄｉａｔｒａｃｈｏｍａｔｉｓに対する免疫原性組成物 |
| EP1812058B1 (en) * | 2004-10-25 | 2012-06-13 | Statens Serum Institut | Chlamydia trachomatis antigens for vaccine and diagnostic use |
| GB0428394D0 (en) * | 2004-12-24 | 2005-02-02 | Chiron Srl | Saccharide conjugate vaccines |
| EP1976557A2 (en) * | 2005-12-22 | 2008-10-08 | Novartis Vaccines and Diagnostics S.r.l. | Chlamydial antigens |
| US9068007B2 (en) * | 2008-10-09 | 2015-06-30 | Board Of Regents, The University Of Texas System | Methods and compositions for chlamydial antigens for diagnosis and treatment of chlamydial infection and disease |
| WO2010078027A1 (en) * | 2008-12-17 | 2010-07-08 | Genocea Biosciences, Inc. | Chlamydia antigens and uses thereof |
| US8568732B2 (en) * | 2009-03-06 | 2013-10-29 | Novartis Ag | Chlamydia antigens |
-
2011
- 2011-10-20 CA CA2849391A patent/CA2849391A1/en not_active Abandoned
- 2011-10-20 AU AU2011316924A patent/AU2011316924A1/en not_active Abandoned
- 2011-10-20 JP JP2013535100A patent/JP2013545448A/ja active Pending
- 2011-10-20 EP EP11835162.6A patent/EP2629793A4/en not_active Withdrawn
- 2011-10-20 WO PCT/US2011/057143 patent/WO2012054755A1/en not_active Ceased
- 2011-10-20 US US13/277,996 patent/US20120135025A1/en not_active Abandoned
-
2016
- 2016-02-24 JP JP2016032672A patent/JP2016106117A/ja active Pending
- 2016-03-24 US US15/080,324 patent/US20170043005A1/en not_active Abandoned
- 2016-04-21 AU AU2016202528A patent/AU2016202528A1/en not_active Abandoned
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