JP2014139185A5 - - Google Patents
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- Publication number
- JP2014139185A5 JP2014139185A5 JP2014027157A JP2014027157A JP2014139185A5 JP 2014139185 A5 JP2014139185 A5 JP 2014139185A5 JP 2014027157 A JP2014027157 A JP 2014027157A JP 2014027157 A JP2014027157 A JP 2014027157A JP 2014139185 A5 JP2014139185 A5 JP 2014139185A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- rhoc
- peptide fragment
- amino acids
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 102000007079 Peptide Fragments Human genes 0.000 claims 16
- 108010033276 Peptide Fragments Proteins 0.000 claims 16
- 150000001413 amino acids Chemical class 0.000 claims 12
- 235000001014 amino acid Nutrition 0.000 claims 11
- 210000001744 T-lymphocyte Anatomy 0.000 claims 8
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 201000011510 cancer Diseases 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 229960005486 vaccine Drugs 0.000 claims 4
- 230000002163 immunogen Effects 0.000 claims 3
- 210000000265 leukocyte Anatomy 0.000 claims 3
- 208000037819 metastatic cancer Diseases 0.000 claims 3
- 208000011575 metastatic malignant neoplasm Diseases 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical group CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Chemical group CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 2
- 235000004279 alanine Nutrition 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 101800001415 Bri23 peptide Proteins 0.000 claims 1
- 102400000107 C-terminal peptide Human genes 0.000 claims 1
- 101800000655 C-terminal peptide Proteins 0.000 claims 1
- 238000011510 Elispot assay Methods 0.000 claims 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- 102000043129 MHC class I family Human genes 0.000 claims 1
- 108091054437 MHC class I family Proteins 0.000 claims 1
- 102000043131 MHC class II family Human genes 0.000 claims 1
- 108091054438 MHC class II family Proteins 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 125000003295 alanine group Chemical group N[C@@H](C)C(=O)* 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000003114 enzyme-linked immunosorbent spot assay Methods 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000011065 in-situ storage Methods 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200701844 | 2007-12-19 | ||
| DKPA200701844 | 2007-12-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538345A Division JP2011506497A (ja) | 2007-12-19 | 2008-12-18 | ＲｈｏＣに基づく免疫療法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015182828A Division JP6084671B2 (ja) | 2007-12-19 | 2015-09-16 | ＲｈｏＣに基づく免疫療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014139185A JP2014139185A (ja) | 2014-07-31 |
| JP2014139185A5 true JP2014139185A5 (enExample) | 2014-09-25 |
| JP5813801B2 JP5813801B2 (ja) | 2015-11-17 |
Family
ID=59270757
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538345A Pending JP2011506497A (ja) | 2007-12-19 | 2008-12-18 | ＲｈｏＣに基づく免疫療法 |
| JP2014027157A Active JP5813801B2 (ja) | 2007-12-19 | 2014-02-17 | ＲｈｏＣに基づく免疫療法 |
| JP2015182828A Active JP6084671B2 (ja) | 2007-12-19 | 2015-09-16 | ＲｈｏＣに基づく免疫療法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538345A Pending JP2011506497A (ja) | 2007-12-19 | 2008-12-18 | ＲｈｏＣに基づく免疫療法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015182828A Active JP6084671B2 (ja) | 2007-12-19 | 2015-09-16 | ＲｈｏＣに基づく免疫療法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9163077B2 (enExample) |
| EP (1) | EP2234635B1 (enExample) |
| JP (3) | JP2011506497A (enExample) |
| AU (1) | AU2008338063B2 (enExample) |
| CA (1) | CA2710061C (enExample) |
| DK (1) | DK2234635T3 (enExample) |
| ES (1) | ES2623447T3 (enExample) |
| PL (1) | PL2234635T3 (enExample) |
| WO (1) | WO2009076966A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2234635T3 (en) * | 2007-12-19 | 2017-05-01 | Rhovac Aps | RhoC-based immunotherapy |
| US10019634B2 (en) * | 2010-06-04 | 2018-07-10 | Masoud Vaziri | Method and apparatus for an eye tracking wearable computer |
| US20190382454A1 (en) * | 2015-03-05 | 2019-12-19 | Amrita Therapeutics Limited | A modified peptide as an anticancer agent |
| JP2021502329A (ja) | 2017-11-08 | 2021-01-28 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｒｈｏａドミナントネガティブフォームを使用して癌を治療するための組成物および方法 |
| KR101947452B1 (ko) * | 2018-04-26 | 2019-02-13 | 주식회사 에스와이테크 | 하이브리드 acp 시스템 및 그 제조방법 |
| KR200488051Y1 (ko) * | 2018-05-28 | 2018-12-07 | 주식회사 에스와이테크 | 완충 z-바 |
| WO2022017895A1 (en) | 2020-07-21 | 2022-01-27 | Rhovac Aps | Treatment of residual disease |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2205499A (en) * | 1997-12-31 | 1999-07-19 | Incyte Pharmaceuticals, Inc. | Human regulatory proteins |
| US6814968B1 (en) | 1998-06-04 | 2004-11-09 | Vanderbilt University | Inhibition of viral infection and spread with viral and RhoA-derived peptides |
| US20030039635A1 (en) * | 1998-09-30 | 2003-02-27 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| CA2390687A1 (en) * | 1999-12-10 | 2001-06-14 | Whitehead Institute For Biomedical Research | Metastasis genes and uses thereof |
| ATE536187T1 (de) * | 2000-10-19 | 2011-12-15 | Epimmune Inc | Hla-klasse-i- und -klasse-ii-bindende peptide und ihre verwendungen |
| WO2002034771A2 (en) * | 2000-10-27 | 2002-05-02 | Chiron Srl | Nucleic acids and proteins from streptococcus groups a & b |
| WO2003008537A2 (en) | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Epitope sequences |
| US7194802B2 (en) * | 2002-03-26 | 2007-03-27 | Seagate Technology Llc | Tool for certifying a head-gimbal assembly |
| DE10217035A1 (de) | 2002-04-11 | 2004-01-22 | Universitätsklinikum Charité Medizinische Fakultät der Humboldt-Universität Akademische Verwaltung - Forschung | Rekrutierungsmodule von RhoA und RhoC |
| US7417026B2 (en) * | 2003-08-13 | 2008-08-26 | Children's Hospital Medical Center | Mobilization of hematopoietic cells |
| US7960100B1 (en) * | 2004-04-30 | 2011-06-14 | Celera Corporation | Colon cancer targets and uses thereof |
| US7763418B2 (en) * | 2005-07-05 | 2010-07-27 | Cytoskeleton, Inc. | Detection of Rho proteins |
| DK2234635T3 (en) * | 2007-12-19 | 2017-05-01 | Rhovac Aps | RhoC-based immunotherapy |
-
2008
- 2008-12-18 DK DK08862897.9T patent/DK2234635T3/en active
- 2008-12-18 CA CA2710061A patent/CA2710061C/en active Active
- 2008-12-18 JP JP2010538345A patent/JP2011506497A/ja active Pending
- 2008-12-18 EP EP08862897.9A patent/EP2234635B1/en active Active
- 2008-12-18 PL PL08862897T patent/PL2234635T3/pl unknown
- 2008-12-18 US US12/808,649 patent/US9163077B2/en active Active
- 2008-12-18 AU AU2008338063A patent/AU2008338063B2/en active Active
- 2008-12-18 ES ES08862897.9T patent/ES2623447T3/es active Active
- 2008-12-18 WO PCT/DK2008/050324 patent/WO2009076966A2/en not_active Ceased
-
2014
- 2014-02-17 JP JP2014027157A patent/JP5813801B2/ja active Active
-
2015
- 2015-09-16 JP JP2015182828A patent/JP6084671B2/ja active Active
- 2015-09-24 US US14/863,691 patent/US20160008448A1/en not_active Abandoned
-
2019
- 2019-04-19 US US16/389,676 patent/US20190247480A1/en not_active Abandoned
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